regorafenib
A multikinase inhibitor, Regorafenib is used in the treatment of metastatic colorectal cancer and advanced gastrointestinal stromal tumors. Shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.Reference standards of Regorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => 4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide
[catalogue_number] => PA 18 49520
[category_ids] => ,79,80,71,76,75,78,70,82,89,
[chemical_name] =>
[weight] => 491.45
[form] => C25H19F2N5O4
[cas] => 2518234-85-8
[pslug] => 2518234-85-8-4-4-amino-3-fluorophenoxy-n-2-fluoro-4-2-methylcarbamoyl-pyridin-4-yl-oxy-phenyl-picolinamide-pa1849520
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4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide
Catalogue No.:PA 18 49520
Molecular Formula : C25H19F2N5O4
Molecular Weight : 491.45
stdClass Object
(
[pname] => 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic Acid
[catalogue_number] => PA 18 49570
[category_ids] => ,71,75,79,80,89,
[chemical_name] =>
[weight] => 469.77
[form] => C20H12ClF4N3O4
[cas] => 1187945-05-6
[pslug] => 1187945-05-6-4-4-3-4-chloro-3-trifluoromethyl-phenyl-ureido-3-fluorophenoxy-picolinic-acid-pa1849570
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4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic Acid
Catalogue No.:PA 18 49570
Molecular Formula : C20H12ClF4N3O4
Molecular Weight : 469.77
stdClass Object
(
[pname] => (2-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamic Acid
[catalogue_number] => PA 18 49610
[category_ids] => ,80,78,70,82,79,89,
[chemical_name] =>
[weight] => 305.26
[form] => C14H12FN3O4
[cas] => NA
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(2-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamic Acid
Catalogue No.:PA 18 49610
Molecular Formula : C14H12FN3O4
Molecular Weight : 305.26
