sofosbuvir

A recently approved nucleotide analog used in the treatment of hepatitis. Sofosbuvir works by inhibiting the hepatitis C NS5B protein. It is a a prodrug of its active antiviral agent GS-461203 Reference standards of Sofosbuvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
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    [pname] => (3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one
    [catalogue_number] => PA 19 51560
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 164.13
    [form] => C6H9FO4
    [cas] => 879551-04-9
    [pslug] => 879551-04-9-3r-4r-5r-3-fluoro-4-hydroxy-5-hydroxymethyl-3-methyl-dihydrofuran-2-3h-one-pa1951560
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PA 19 51560

(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one

  • Catalogue No.:PA 19 51560

  • CAS :

    879551-04-9

  • Molecular Formula : C6H9FO4

  • Molecular Weight : 164.13

Enquire
Details 
stdClass Object
(
    [pname] => ((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl Benzoate
    [catalogue_number] => PA 19 51570
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 372.34
    [form] => C20H17FO6
    [cas] => 874638-80-9
    [pslug] => 874638-80-9-2r-3r-4r-3-benzoyloxy-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl-methyl-benzoate-pa1951570
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PA 19 51570

((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl Benzoate

  • Catalogue No.:PA 19 51570

  • CAS :

    874638-80-9

  • Molecular Formula : C20H17FO6

  • Molecular Weight : 372.34

Enquire
Details 
stdClass Object
(
    [pname] => [(2R,3R,4R,5R)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl]methyl Benzoate
    [catalogue_number] => PA 19 51580
    [category_ids] => 76,89,70,78,82
    [chemical_name] => 
    [weight] => 374.36
    [form] => C20H19FO6
    [cas] => 1199809-22-7
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PA 19 51580

[(2R,3R,4R,5R)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl]methyl Benzoate

  • Catalogue No.:PA 19 51580

  • CAS :

    1199809-22-7

  • Molecular Formula : C20H19FO6

  • Molecular Weight : 374.36

Enquire
Details 
stdClass Object
(
    [pname] => [(2R,3R,4R,5S)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl]methyl Benzoate
    [catalogue_number] => PA 19 51590
    [category_ids] => 82,78,70,89,76
    [chemical_name] => 
    [weight] => 374.36
    [form] => C20H19FO6
    [cas] => 1639301-16-8
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PA 19 51590

[(2R,3R,4R,5S)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl]methyl Benzoate

  • Catalogue No.:PA 19 51590

  • CAS :

    1639301-16-8

  • Molecular Formula : C20H19FO6

  • Molecular Weight : 374.36

Enquire
Details 
stdClass Object
(
    [pname] => [(2R,3R,4R,5R)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl]methyl Benzoate
    [catalogue_number] => PA 19 51600
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 392.81
    [form] => C20H18ClFO5
    [cas] => 1199809-23-8
    [pslug] => 1199809-23-8-2r-3r-4r-5r-3-benzoyloxy-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl-methyl-benzoate-pa1951600
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PA 19 51600

[(2R,3R,4R,5R)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl]methyl Benzoate

  • Catalogue No.:PA 19 51600

  • CAS :

    1199809-23-8

  • Molecular Formula : C20H18ClFO5

  • Molecular Weight : 392.81

Enquire
Details 
stdClass Object
(
    [pname] => [(2R,3R,4R,5S)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl]methyl Benzoate
    [catalogue_number] => PA 19 51610
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 392.81
    [form] => C20H18ClFO5
    [cas] => 1500076-79-8
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PA 19 51610

[(2R,3R,4R,5S)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl]methyl Benzoate

  • Catalogue No.:PA 19 51610

  • CAS :

    1500076-79-8

  • Molecular Formula : C20H18ClFO5

  • Molecular Weight : 392.81

Enquire
Details 
stdClass Object
(
    [pname] => (2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate
    [catalogue_number] => PA 19 51620
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 571.55
    [form] => C31H26FN3O7
    [cas] => 817204-32-3
    [pslug] => 817204-32-3-2r-3r-4r-5r-5-4-benzamido-2-oxopyrimidin-1-2h-yl-2-benzoyloxy-methyl-4-fluoro-4-methyltetrahydrofuran-3-yl-benzoate-pa1951620
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PA 19 51620

(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate

  • Catalogue No.:PA 19 51620

  • CAS :

    817204-32-3

  • Molecular Formula : C31H26FN3O7

  • Molecular Weight : 571.55

Enquire
Details 
stdClass Object
(
    [pname] => ((2R,3R,4R,5R)-3-(Benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl Benzoate
    [catalogue_number] => PA 19 51630
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 468.43
    [form] => C24H21FN2O7
    [cas] => 863329-65-1
    [pslug] => 863329-65-1-2r-3r-4r-5r-3-benzoyloxy-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-4-fluoro-4-methyltetrahydrofuran-2-yl-methyl-benzoate-pa1951630
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PA 19 51630

((2R,3R,4R,5R)-3-(Benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl Benzoate

  • Catalogue No.:PA 19 51630

  • CAS :

    863329-65-1

  • Molecular Formula : C24H21FN2O7

  • Molecular Weight : 468.43

Enquire
Details 
stdClass Object
(
    [pname] => 1-((2S,3S,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
    [catalogue_number] => PA 19 51640
    [category_ids] => 76,89,70,78,82
    [chemical_name] => 
    [weight] => 260.22
    [form] => C10H13FN2O5
    [cas] => 1946820-96-7
    [pslug] => 1946820-96-7-1-2s-3s-4s-5s-3-fluoro-4-hydroxy-5-hydroxymethyl-3-methyltetrahydrofuran-2-yl-pyrimidine-2-4-1h-3h-dione-pa1951640
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PA 19 51640

1-((2S,3S,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

  • Catalogue No.:PA 19 51640

  • CAS :

    1946820-96-7

  • Molecular Formula : C10H13FN2O5

  • Molecular Weight : 260.22

Enquire
Details 
stdClass Object
(
    [pname] => 1-((2S,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
    [catalogue_number] => PA 19 51650
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 260.22
    [form] => C10H13FN2O5
    [cas] => 2041584-99-8
    [pslug] => 2041584-99-8-1-2s-3r-4r-5r-3-fluoro-4-hydroxy-5-hydroxymethyl-3-methyltetrahydrofuran-2-yl-pyrimidine-2-4-1h-3h-dione-pa1951650
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PA 19 51650

1-((2S,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

  • Catalogue No.:PA 19 51650

  • CAS :

    2041584-99-8

  • Molecular Formula : C10H13FN2O5

  • Molecular Weight : 260.22

Enquire
Details 
stdClass Object
(
    [pname] => Mixture of (Pentafluorophenol, Sofosbuvir-14-ethyl impurity, Sofosbuvir-14, And n-Propyl Sofosbuvir-14)
    [catalogue_number] => PA 19 51720
    [category_ids] => ,71,85,78,70,82,72,89,
    [chemical_name] => 
    [weight] => 1529.93
    [form] => C59H50F20N3O16P3
    [cas] => NA
    [pslug] => mixture-of-pentafluorophenol-sofosbuvir-14-ethyl-impurity-sofosbuvir-14-and-n-propyl-sofosbuvir-14-pa1951720
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PA 19 51720

Mixture of (Pentafluorophenol, Sofosbuvir-14-ethyl impurity, Sofosbuvir-14, And n-Propyl Sofosbuvir-14)

  • Catalogue No.:PA 19 51720

  • CAS :

    NA

  • Molecular Formula : C59H50F20N3O16P3

  • Molecular Weight : 1529.93

Enquire
Details 
stdClass Object
(
    [pname] => Mixture of (Sofosbuvir-14 And L-Rp-Sofosbuvir-14)
    [catalogue_number] => PA 19 51730
    [category_ids] => ,71,85,78,70,82,72,89,
    [chemical_name] => 
    [weight] => 906.59
    [form] => C36H34F10N2O10P2
    [cas] => NA
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PA 19 51730

Mixture of (Sofosbuvir-14 And L-Rp-Sofosbuvir-14)

  • Catalogue No.:PA 19 51730

  • CAS :

    NA

  • Molecular Formula : C36H34F10N2O10P2

  • Molecular Weight : 906.59

Enquire
Details 
stdClass Object
(
    [pname] => Mixture of (Pentafluorophenol, Sofosbuvir, Rp-Sofosbuvir, n-Propyl Sofosbuvir)
    [catalogue_number] => PA 19 51740
    [category_ids] => ,71,85,78,70,82,72,89,
    [chemical_name] => 
    [weight] => 1772.42
    [form] => C72H88F8N9O28P3
    [cas] => NA
    [pslug] => mixture-of-pentafluorophenol-sofosbuvir-rp-sofosbuvir-n-propyl-sofosbuvir-pa1951740
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PA 19 51740

Mixture of (Pentafluorophenol, Sofosbuvir, Rp-Sofosbuvir, n-Propyl Sofosbuvir)

  • Catalogue No.:PA 19 51740

  • CAS :

    NA

  • Molecular Formula : C72H88F8N9O28P3

  • Molecular Weight : 1772.42

Enquire
Details 
stdClass Object
(
    [pname] => Sofosbuvir-12 And Sofosbuvir-12 Anomer
    [catalogue_number] => PA 19 51750
    [category_ids] => ,71,78,70,82,89,
    [chemical_name] => 
    [weight] => 1143.1
    [form] => C62H52F2N6O14
    [cas] => NA
    [pslug] => sofosbuvir-12-and-sofosbuvir-12-anomer-pa1951750
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PA 19 51750

Sofosbuvir-12 And Sofosbuvir-12 Anomer

  • Catalogue No.:PA 19 51750

  • CAS :

    NA

  • Molecular Formula : C62H52F2N6O14

  • Molecular Weight : 1143.1

Enquire
Details 
stdClass Object
(
    [pname] => Mixture of (Sofosbuvir-7 Sofosbuvir-7 Anomer)
    [catalogue_number] => PA 19 51760
    [category_ids] => ,71,78,70,82,89,
    [chemical_name] => 
    [weight] => 520.44
    [form] => C20H26F2N4O10
    [cas] => NA
    [pslug] => mixture-of-sofosbuvir-7-sofosbuvir-7-anomer-pa1951760
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PA 19 51760

Mixture of (Sofosbuvir-7 Sofosbuvir-7 Anomer)

  • Catalogue No.:PA 19 51760

  • CAS :

    NA

  • Molecular Formula : C20H26F2N4O10

  • Molecular Weight : 520.44

Enquire
Details 
stdClass Object
(
    [pname] => 1-((3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
    [catalogue_number] => PA 19 51910
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 260.22
    [form] => C10H13FN2O5
    [cas] => NA
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PA 19 51910

1-((3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

  • Catalogue No.:PA 19 51910

  • CAS :

    NA

  • Molecular Formula : C10H13FN2O5

  • Molecular Weight : 260.22

Enquire
Details 
stdClass Object
(
    [pname] => (2S,2'S)-Isopropyl 2,2'-phenoxyphosphoryl-bis-azanediyl dipropanoate
    [catalogue_number] => PA 19 51920
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 400.41
    [form] => C18H29N2O6P
    [cas] => NA
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PA 19 51920

(2S,2'S)-Isopropyl 2,2'-phenoxyphosphoryl-bis-azanediyl dipropanoate

  • Catalogue No.:PA 19 51920

  • CAS :

    NA

  • Molecular Formula : C18H29N2O6P

  • Molecular Weight : 400.41

Enquire
Details 
stdClass Object
(
    [pname] => Isopropyl ((((2R,3R,4R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate
    [catalogue_number] => PA 19 51930
    [category_ids] => ,76,78,70,82,89,
    [chemical_name] => 
    [weight] => 798.69
    [form] => C34H45FN4O13P2
    [cas] => NA
    [pslug] => isopropyl-2r-3r-4r-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-4-fluoro-2-s-1-isopropoxy-1-oxopropan-2-yl-amino-phenoxy-phosphoryl-oxy-methyl-4-methyltetrahydrofuran-3-yl-oxy-phenoxy-phosphoryl-l-alaninate-pa1951930
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PA 19 51930

Isopropyl ((((2R,3R,4R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate

  • Catalogue No.:PA 19 51930

  • CAS :

    NA

  • Molecular Formula : C34H45FN4O13P2

  • Molecular Weight : 798.69

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CPHI INDIA- 28, 30 November