sorafenib
A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Sorafenib β-D-Glucuronide
[catalogue_number] => PA 19 69540
[category_ids] => ,70,71,75,79,80,82,89,95,
[chemical_name] =>
[weight] => 640.95
[form] => C27H24ClF3N4O9
[cas] => 1130164-93-0
[pslug] => 1130164-93-0-sorafenib-beta-d-glucuronide-pa1969540
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Sorafenib β-D-Glucuronide
Catalogue No.:PA 19 69540
Molecular Formula : C27H24ClF3N4O9
Molecular Weight : 640.95
stdClass Object
(
[pname] => Sorafenib Hemi-Tosylate
[catalogue_number] => PA 19 69550
[category_ids] => ,89,80,79,75,71,82,70,
[chemical_name] =>
[weight] => 464.83
[form] => C21H16ClF3N4O3 .1/2 C7H8O3S
[cas] => 2056030-06-7
[pslug] => 2056030-06-7-sorafenib-hemi-tosylate-pa1969550
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Catalogue No.:PA 19 69550
Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S
Molecular Weight : 464.83