apixaban
Apixaban, sold under the trade name Eliquis among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation.. Reference standards of Apixaban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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[pname] => Apixaban - API Standards
[catalogue_number] => PA 28 11000
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[chemical_name] =>
[weight] => 459.50
[form] => C25H25N5O4
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Catalogue No.:PA 28 11000
Molecular Formula : C25H25N5O4
Molecular Weight : 459.50
stdClass Object
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[pname] => O-Desmethyl Apixaban
[catalogue_number] => PA 28 11510
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[chemical_name] =>
[weight] => 445.47
[form] => C24H23N5O4
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Catalogue No.:PA 28 11510
Molecular Formula : C24H23N5O4
Molecular Weight : 445.47
stdClass Object
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[pname] => 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid
[catalogue_number] => PA 28 11560
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[chemical_name] =>
[weight] => 477.51
[form] => C25H27N5O5
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3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid
Catalogue No.:PA 28 11560
Molecular Formula : C25H27N5O5
Molecular Weight : 477.51
stdClass Object
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[pname] => Apixaban Methyl Ester Impurity
[catalogue_number] => PA 28 11610
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[chemical_name] =>
[weight] => 474.51
[form] => C26H26N4O5
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Apixaban Methyl Ester Impurity
Catalogue No.:PA 28 11610
Molecular Formula : C26H26N4O5
Molecular Weight : 474.51
stdClass Object
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[pname] => Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
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[chemical_name] =>
[weight] => 525
[form] => C27H29ClN4O5
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Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
stdClass Object
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[pname] => O-Desmethyl Apixaban Sulfate
[catalogue_number] => PA 28 11520
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[weight] => 525.53
[form] => C24H23N5O7S
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O-Desmethyl Apixaban Sulfate
Catalogue No.:PA 28 11520
Molecular Formula : C24H23N5O7S
Molecular Weight : 525.53
stdClass Object
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[pname] => Hydroxy Apixaban
[catalogue_number] => PA 28 11530
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[weight] => 475.5
[form] => C25H25N5O5
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[pname] => Hydroxy O-Demethyl Apixaban
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[weight] => 461.47
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Hydroxy O-Demethyl Apixaban
Catalogue No.:PA 28 11540
Molecular Formula : C24H23N5O5
Molecular Weight : 461.47
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[pname] => Hydroxy O-Demethyl Apixaban Sulfate
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[weight] => 541.53
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Hydroxy O-Demethyl Apixaban Sulfate
Catalogue No.:PA 28 11550
Molecular Formula : C24H23N5O8S
Molecular Weight : 541.53
stdClass Object
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[pname] => Apixaban Carboxylic Acid Impurity
[catalogue_number] => PA 28 11570
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[weight] => 460.48
[form] => C25H24N4O5
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Apixaban Carboxylic Acid Impurity
Catalogue No.:PA 28 11570
Molecular Formula : C25H24N4O5
Molecular Weight : 460.48
stdClass Object
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[pname] => 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid
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[weight] => 378.38
[form] => C20H18N4O4
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6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid
Catalogue No.:PA 28 11580
Molecular Formula : C20H18N4O4
Molecular Weight : 378.38
stdClass Object
(
[pname] => Methyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
[catalogue_number] => PA 28 11600
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[weight] => 392.41
[form] => C21H20N4O4
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Methyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Catalogue No.:PA 28 11600
Molecular Formula : C21H20N4O4
Molecular Weight : 392.41
stdClass Object
(
[pname] => Methyl 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoate
[catalogue_number] => PA 28 11620
[category_ids] => ,80,71,76,75,78,70,82,
[chemical_name] =>
[weight] => 491.54
[form] => C26H29N5O5
[cas] => 2203740-09-2
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Methyl 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoate
Catalogue No.:PA 28 11620
Molecular Formula : C26H29N5O5
Molecular Weight : 491.54
stdClass Object
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[pname] => Apixaban Dehydro Impurity
[catalogue_number] => PA 28 11630
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[chemical_name] =>
[weight] => 457.48
[form] => C25H23N5O4
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Apixaban Dehydro Impurity
Catalogue No.:PA 28 11630
Molecular Formula : C25H23N5O4
Molecular Weight : 457.48
stdClass Object
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[pname] => Apixaban Carboxylic Acid O-Desmethyl Impurity
[catalogue_number] => PA 28 11640
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[chemical_name] =>
[weight] => 446.46
[form] => C24H22N4O5
[cas] => NA
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Apixaban Carboxylic Acid O-Desmethyl Impurity
Catalogue No.:PA 28 11640
Molecular Formula : C24H22N4O5
Molecular Weight : 446.46
stdClass Object
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[pname] => Apixaban Chloro Impurity
[catalogue_number] => PA 28 11650
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[chemical_name] =>
[weight] => 463.92
[form] => C24H22ClN5O3
[cas] => 2029205-64-7
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Catalogue No.:PA 28 11650
Molecular Formula : C24H22ClN5O3
Molecular Weight : 463.92
stdClass Object
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[pname] => Apixaban Isopropyl Ester Impurity
[catalogue_number] => PA 28 11670
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[weight] => 502.56
[form] => C28H30N4O5
[cas] => NA
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Apixaban Isopropyl Ester Impurity
Catalogue No.:PA 28 11670
Molecular Formula : C28H30N4O5
Molecular Weight : 502.56
stdClass Object
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[pname] => 6-(4-((5-Amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
[catalogue_number] => PA 28 11680
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[weight] => 476.53
[form] => C25H28N6O4
[cas] => 2187409-01-2
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6-(4-((5-Amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Catalogue No.:PA 28 11680
Molecular Formula : C25H28N6O4
Molecular Weight : 476.53
stdClass Object
(
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[catalogue_number] => PA 28 11690
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[weight] => 473.52
[form] => C26H27N5O4
[cas] => 1686149-74-5
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1-(4-Methoxyphenyl)-6-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Catalogue No.:PA 28 11690
Molecular Formula : C26H27N5O4
Molecular Weight : 473.52
stdClass Object
(
[pname] => 1-(4-Methoxyphenyl)-6-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
[catalogue_number] => PA 28 11700
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[weight] => 473.52
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1-(4-Methoxyphenyl)-6-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Catalogue No.:PA 28 11700
Molecular Formula : C26H27N5O4
Molecular Weight : 473.52
stdClass Object
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[pname] => (E)-Ethyl 2-(2-(4-methoxyphenyl)hydrazono)propanoate
[catalogue_number] => PA 28 11710
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[chemical_name] =>
[weight] => 236.27
[form] => C12H16N2O3
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(E)-Ethyl 2-(2-(4-methoxyphenyl)hydrazono)propanoate
Catalogue No.:PA 28 11710
Molecular Formula : C12H16N2O3
Molecular Weight : 236.27
stdClass Object
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[catalogue_number] => PA 28 11720
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[weight] => 252.65
[form] => C11H9ClN2O3
[cas] => 536760-29-9
[pslug] => 536760-29-9-3-chloro-1-4-nitrophenyl-5-6-dihydropyridin-2-1h-one-pa2811720
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3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
Catalogue No.:PA 28 11720
Molecular Formula : C11H9ClN2O3
Molecular Weight : 252.65
stdClass Object
(
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[catalogue_number] => PA 28 11760
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 445.47
[form] => C24H23N5O4
[cas] => NA
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1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopyrrolidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Catalogue No.:PA 28 11760
Molecular Formula : C24H23N5O4
Molecular Weight : 445.47
stdClass Object
(
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[catalogue_number] => PA 28 11770
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 377.4
[form] => C20H19N5O3
[cas] => 1423803-24-0
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6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
stdClass Object
(
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[catalogue_number] => PA 28 11780
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 529.59
[form] => C29H31N5O5
[cas] => NA
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1-(4-Methoxyphenyl)-3-(morpholine-4-carbonyl)-6-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one
Catalogue No.:PA 28 11780
Molecular Formula : C29H31N5O5
Molecular Weight : 529.59
stdClass Object
(
[pname] => (E)-1,2-Bis(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)diazene oxide
[catalogue_number] => PA 28 11790
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 766.76
[form] => C40H34N10O7
[cas] => NA
[pslug] => e-1-2-bis-4-3-carbamoyl-1-4-methoxyphenyl-7-oxo-4-5-dihydro-1h-pyrazolo-3-4-c-pyridin-6-7h-yl-phenyl-diazene-oxide-pa2811790
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(E)-1,2-Bis(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)diazene oxide
Catalogue No.:PA 28 11790
Molecular Formula : C40H34N10O7
Molecular Weight : 766.76
stdClass Object
(
[pname] => 5-Chloro-N-(4-(3-morpholino-2-oxo-5,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide
[catalogue_number] => PA 28 11800
[category_ids] => 82,80,78,75,71,70
[chemical_name] =>
[weight] => 391.89
[form] => C20H26ClN3O3
[cas] => 1643330-62-4
[pslug] => 1643330-62-4-5-chloro-n-4-3-morpholino-2-oxo-5-6-dihydropyridin-1-2h-yl-phenyl-pentanamide-pa2811800
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5-Chloro-N-(4-(3-morpholino-2-oxo-5,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide
Catalogue No.:PA 28 11800
Molecular Formula : C20H26ClN3O3
Molecular Weight : 391.89
stdClass Object
(
[pname] => (Z)-Ethyl 2-chloro-2-(2-(3-methoxyphenyl)hydrazono)acetate
[catalogue_number] => PA 28 11820
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 256.69
[form] => C11H13ClN2O3
[cas] => 405872-78-8
[pslug] => 405872-78-8-z-ethyl-2-chloro-2-2-3-methoxyphenyl-hydrazono-acetate-pa2811820
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(Z)-Ethyl 2-chloro-2-(2-(3-methoxyphenyl)hydrazono)acetate
Catalogue No.:PA 28 11820
Molecular Formula : C11H13ClN2O3
Molecular Weight : 256.69
stdClass Object
(
[pname] => N-Formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
[catalogue_number] => PA 28 11830
[category_ids] => 82,80,78,75,71,70
[chemical_name] =>
[weight] => 487.51
[form] => C26H25N5O5
[cas] => 1351611-14-7
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N-Formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Catalogue No.:PA 28 11830
Molecular Formula : C26H25N5O5
Molecular Weight : 487.51
stdClass Object
(
[pname] => Ethyl-2-chloro-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]acetate
[catalogue_number] => PA 28 11840
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 256.69
[form] => C11H13ClN2O3
[cas] => 1644619-42-0
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Ethyl-2-chloro-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]acetate
Catalogue No.:PA 28 11840
Molecular Formula : C11H13ClN2O3
Molecular Weight : 256.69
stdClass Object
(
[pname] => 3-(Morpholinyl)-N-(4-nitrophenyl)-5,6-dihydropyridin-2-one
[catalogue_number] => PA 28 11850
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 303.31
[form] => C15H17N3O4
[cas] => 503615-03-0
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3-(Morpholinyl)-N-(4-nitrophenyl)-5,6-dihydropyridin-2-one
Catalogue No.:PA 28 11850
Molecular Formula : C15H17N3O4
Molecular Weight : 303.31
stdClass Object
(
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[catalogue_number] => PA 28 0111057
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[weight] => 222.67
[form] => C11H11ClN2O
[cas] => 1801881-15-1
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1-(4-Aminophenyl)-3-chloro-5,6-dihydropyridin-2(1H)-one
Catalogue No.:PA 28 0111057
Molecular Formula : C11H11ClN2O
Molecular Weight : 222.67
stdClass Object
(
[pname] => 1-(4-Methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
[catalogue_number] => PA 28 0111060
[category_ids] => ,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 546.63
[form] => C29H34N6O5
[cas] => NA
[pslug] => 1-4-methoxyphenyl-7a-morpholino-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-3a-4-5-6-7-7a-hexahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxamide-pa280111060
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1-(4-Methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Catalogue No.:PA 28 0111060
Molecular Formula : C29H34N6O5
Molecular Weight : 546.63
stdClass Object
(
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[catalogue_number] => PA 28 0111061
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[weight] => 273.34
[form] => C15H19N3O2
[cas] => 2437650-75-2
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1-(3-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one
Catalogue No.:PA 28 0111061
Molecular Formula : C15H19N3O2
Molecular Weight : 273.34
stdClass Object
(
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[catalogue_number] => PA 28 0111062
[category_ids] => ,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 190.25
[form] => C11H14N2O
[cas] => 438056-68-9
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1-(4-Aminophenyl)piperidin-2-one
Catalogue No.:PA 28 0111062
Molecular Formula : C11H14N2O
Molecular Weight : 190.25
stdClass Object
(
[pname] => Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
[catalogue_number] => PA 28 0111065
[category_ids] => ,80,71,81,78,70,82,
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[weight] => 488.54
[form] => C27H28N4O5
[cas] => 1801881-20-8
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Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Catalogue No.:PA 28 0111065
Molecular Formula : C27H28N4O5
Molecular Weight : 488.54
stdClass Object
(
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[catalogue_number] => PA 28 0111066
[category_ids] => ,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 458.52
[form] => C26H26N4O4
[cas] => 1801881-21-9
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Ethyl 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Catalogue No.:PA 28 0111066
Molecular Formula : C26H26N4O4
Molecular Weight : 458.52
stdClass Object
(
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[weight] => 402.45
[form] => C20H26N4O5
[cas] => NA
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5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)(nitroso)amino)pentanoic Acid
Catalogue No.:PA 28 0111067
Molecular Formula : C20H26N4O5
Molecular Weight : 402.45
stdClass Object
(
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[catalogue_number] => PA 28 0111068
[category_ids] => ,80,71,81,78,70,82,162,
[chemical_name] =>
[weight] => 420.89
[form] => C20H25ClN4O4
[cas] => NA
[pslug] => 5-chloro-n-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-n-nitrosopentanamide-pa280111068
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5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide
Catalogue No.:PA 28 0111068
Molecular Formula : C20H25ClN4O4
Molecular Weight : 420.89
stdClass Object
(
[pname] => N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide
[catalogue_number] => PA 28 0111071
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[chemical_name] =>
[weight] => 301.35
[form] => C16H19N3O3
[cas] => NA
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N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide
Catalogue No.:PA 28 0111071
Molecular Formula : C16H19N3O3
Molecular Weight : 301.35
stdClass Object
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[weight] => 357.45
[form] => C20H27N3O3
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3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one
Catalogue No.:PA 28 0111072
Molecular Formula : C20H27N3O3
Molecular Weight : 357.45
stdClass Object
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[catalogue_number] => PA 28 0111073
[category_ids] => ,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 357.45
[form] => C20H27N3O3
[cas] => NA
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3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one
Catalogue No.:PA 28 0111073
Molecular Formula : C20H27N3O3
Molecular Weight : 357.45
stdClass Object
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[pname] => Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
[catalogue_number] => PA 28 0111074
[category_ids] => ,80,71,81,78,70,82,
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[weight] => 486.53
[form] => C27H26N4O5
[cas] => 2514951-00-7
[pslug] => 2514951-00-7-ethyl-1-4-methoxyphenyl-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-6-7-dihydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111074
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Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Catalogue No.:PA 28 0111074
Molecular Formula : C27H26N4O5
Molecular Weight : 486.53