argatroban
The American College of Cardiologists recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia and are undergoing percutaneous coronary intervention. It is a direct, selective thrombin inhibitor.. Reference standards of Argatroban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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Argatroban - API Standards
Catalogue No.:PA 01 68000
Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
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(2S,4S)-1-[(2S)-2-Amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid Benzyl Ester Hydrochloride
Catalogue No.:PA 01 68510
Molecular Formula : C20H31ClN6O5
Molecular Weight : 470.95
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(2R,4R)-rel-N-tert-Butyloxycarbonyl-4-methyl-2-piperidinecarboxylic Acid Benzyl Ester
Catalogue No.:PA 01 68520
Molecular Formula : C19H27NO4
Molecular Weight : 333.42
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(2S,4S)-1-[(2S)-2-[(tert-Butyloxycarbonyl)amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid Benzyl Ester
Catalogue No.:PA 01 68530
Molecular Formula : C25H38N6O7
Molecular Weight : 534.61
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(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid Benzyl Ester
Catalogue No.:PA 01 68540
Molecular Formula : C25H38N6O7
Molecular Weight : 534.61
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Ethyl (2R,4R)-4-Methylpipecolate
Catalogue No.:PA 01 68550
Molecular Formula : C9H17NO2
Molecular Weight : 171.24
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Ethyl (2R,4S)-4-Methylpipecolate
Catalogue No.:PA 01 68560
Molecular Formula : C9H17NO2
Molecular Weight : 171.24
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Ethyl (2S,4R)-4-Methylpipecolate
Catalogue No.:PA 01 68570
Molecular Formula : C9H17NO2
Molecular Weight : 171.24
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Ethyl (2S,4S)-4-Methylpipecolate
Catalogue No.:PA 01 68580
Molecular Formula : C9H17NO2
Molecular Weight : 171.24
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N-Nitro-1,2,3,4-tetradehydro Argatroban
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N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester
Catalogue No.:PA 01 68600
Molecular Formula : C25H35N7O7S
Molecular Weight : 577.65
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N-Nitro-1,2,3,4-tetradehydro (2S,4S)-Argatroban Benzyl Ester
Catalogue No.:PA 01 68610
Molecular Formula : C30H37N7O7S
Molecular Weight : 639.72
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Catalogue No.:PA 01 68620
Molecular Formula : C25H40N6O5S
Molecular Weight : 536.69
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Catalogue No.:PA 01 68630
Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
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Catalogue No.:PA 01 68640
Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
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Catalogue No.:PA 01 68650
Molecular Formula : C22H35ClN4O5S
Molecular Weight : 503.06
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Catalogue No.:PA 01 68660
Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
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Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
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Molecular Formula : C23H36N6O5S
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Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
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(2S,4R)-1-((2S)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic Acid
Catalogue No.:PA 01 68700
Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
stdClass Object
(
[pname] => (2R,4S)-1-((2R)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic Acid
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(2R,4S)-1-((2R)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic Acid
Catalogue No.:PA 01 68710
Molecular Formula : C23H36N6O5S
Molecular Weight : 508.63
stdClass Object
(
[pname] => (2R,4R)-Ethyl 4-methyl-1-((3-methylquinolin-8-yl)sulfonyl)piperidine-2-carboxylate
[catalogue_number] => PA 01 68720
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[chemical_name] =>
[weight] => 376.47
[form] => C19H24N2O4S
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(2R,4R)-Ethyl 4-methyl-1-((3-methylquinolin-8-yl)sulfonyl)piperidine-2-carboxylate
Catalogue No.:PA 01 68720
Molecular Formula : C19H24N2O4S
Molecular Weight : 376.47
stdClass Object
(
[pname] => (2R,4R)1-[(2S)2-Amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid Ethyl Ester Hydrochloride
[catalogue_number] => PA 01 68730
[category_ids] => ,79,69,71,78,70,82,88,
[chemical_name] =>
[weight] => 408.88
[form] => C15H29ClN6O5
[cas] => 74874-08-1
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(2R,4R)1-[(2S)2-Amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid Ethyl Ester Hydrochloride
Catalogue No.:PA 01 68730
Molecular Formula : C15H29ClN6O5
Molecular Weight : 408.88
stdClass Object
(
[pname] => (2R,4R)-4-Methyl-1-((2S)-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)-5-(3-nitroguanidino)pentanoyl)piperidine-2-carboxylic Acid
[catalogue_number] => PA 01 68740
[category_ids] => 88,82,79,78,71,70
[chemical_name] =>
[weight] => 553.63
[form] => C23H35N7O7S
[cas] => 1448301-07-2
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(2R,4R)-4-Methyl-1-((2S)-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)-5-(3-nitroguanidino)pentanoyl)piperidine-2-carboxylic Acid
Catalogue No.:PA 01 68740
Molecular Formula : C23H35N7O7S
Molecular Weight : 553.63
stdClass Object
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[pname] => Argatroban-d3
[catalogue_number] => PA STI 008610
[category_ids] => ,79,69,71,78,70,82,88,98,
[chemical_name] =>
[weight] => 511.65
[form] => C23H33D3N6O5S
[cas] => 1356847-56-7
[pslug] => 1356847-56-7-argatroban-d3-pasti008610
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Catalogue No.:PA STI 008610
Molecular Formula : C23H33D3N6O5S
Molecular Weight : 511.65
stdClass Object
(
[pname] => (2R,4R)-4-Methyl-1-(((3-methyl-1-nitroso-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl)-L-arginyl)piperidine-2-carboxylic Acid
[catalogue_number] => PA 01 0681015
[category_ids] => ,69,70,71,78,79,82,88,162,
[chemical_name] =>
[weight] => 537.64
[form] => C23H35N7O6S
[cas] => NA
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(2R,4R)-4-Methyl-1-(((3-methyl-1-nitroso-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl)-L-arginyl)piperidine-2-carboxylic Acid
Catalogue No.:PA 01 0681015
Molecular Formula : C23H35N7O6S
Molecular Weight : 537.64
stdClass Object
(
[pname] => cis-4-Aminocyclohexanecarboxylic Acid
[catalogue_number] => PA 01 0681016
[category_ids] => ,79,69,71,78,70,82,
[chemical_name] =>
[weight] => 143.19
[form] => C7H13NO2
[cas] => 3685-23-2
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cis-4-Aminocyclohexanecarboxylic Acid
Catalogue No.:PA 01 0681016
Molecular Formula : C7H13NO2
Molecular Weight : 143.19
stdClass Object
(
[pname] => 3-Methyl-1,2,3,4-tetrahydroquinoline-8-sulfonic Acid
[catalogue_number] => PA 01 0681017
[category_ids] => ,69,71,78,70,82,
[chemical_name] =>
[weight] => 227.28
[form] => C10H13NO3S
[cas] => 153886-68-1
[pslug] => 153886-68-1-3-methyl-1-2-3-4-tetrahydroquinoline-8-sulfonic-acid-pa010681017
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3-Methyl-1,2,3,4-tetrahydroquinoline-8-sulfonic Acid
Catalogue No.:PA 01 0681017
Molecular Formula : C10H13NO3S
Molecular Weight : 227.28
stdClass Object
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[catalogue_number] => PA 01 0681018
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[chemical_name] =>
[weight] => 285.36
[form] => C13H19NO4S
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2-Hydroxypropyl 3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonate
Catalogue No.:PA 01 0681018
Molecular Formula : C13H19NO4S
Molecular Weight : 285.36
stdClass Object
(
[pname] => Nomega-Nitro-L-arginine methyl ester Hydrochloride
[catalogue_number] => PA 01 0681019
[category_ids] => ,79,69,71,78,70,82,
[chemical_name] =>
[weight] => 269.69
[form] => C7H16ClN5O4
[cas] => 51298-62-5
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Nomega-Nitro-L-arginine methyl ester Hydrochloride
Catalogue No.:PA 01 0681019
Molecular Formula : C7H16ClN5O4
Molecular Weight : 269.69
stdClass Object
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[pname] => 4-Methylpiperidine-2-carboxylic Acid
[catalogue_number] => PA 01 0681020
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[weight] => 143.19
[form] => C7H13NO2
[cas] => 172823-76-6
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4-Methylpiperidine-2-carboxylic Acid
Catalogue No.:PA 01 0681020
Molecular Formula : C7H13NO2
Molecular Weight : 143.19
stdClass Object
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[catalogue_number] => PA 01 0681021
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[weight] => 143.19
[form] => C7H13NO2
[cas] => 79199-63-6
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(2S,4S)-4-Methylpiperidine-2-carboxylic Acid
Catalogue No.:PA 01 0681021
Molecular Formula : C7H13NO2
Molecular Weight : 143.19
stdClass Object
(
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[catalogue_number] => PA 01 0681022
[category_ids] => ,69,71,78,70,
[chemical_name] =>
[weight] => 171.24
[form] => C9H17NO2
[cas] => 66937-93-7
[pslug] => 66937-93-7-ethyl-4-methylpiperidine-2-carboxylate-pa010681022
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Ethyl 4-methylpiperidine-2-carboxylate
Catalogue No.:PA 01 0681022
Molecular Formula : C9H17NO2
Molecular Weight : 171.24