Cabozantinib-impurities | Pharmaffiliates

cabozantinib

Cabozantinib is used in two forms. A capsule form is used since 2012 to treat medullary thyroid cancer and a tablet form is used since 2016 as a second line treatment for renal cell carcinoma.. Reference standards of Cabozantinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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(
    [pname] => Cabozantinib - API Standards 
    [catalogue_number] => PA 30 62000
    [category_ids] => ,79,80,71,78,70,82,89,
    [chemical_name] => 
    [weight] => 501.51
    [form] => C28H24FN3O5
    [cas] => 849217-68-1
    [pslug] => 849217-68-1-cabozantinib-api-pa3062000
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PA 30 62000

Cabozantinib - API Standards


  • Catalogue No.:PA 30 62000

  • CAS :

    849217-68-1

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

stdClass Object
(
    [pname] => Cabozantinib Chloro Analog
    [catalogue_number] => PA 30 62530
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 223.66
    [form] => C11H10ClNO2
    [cas] => 35654-56-9
    [pslug] => 35654-56-9-cabozantinib-chloro-analog-pa3062530
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PA 30 62530

Cabozantinib Chloro Analog


  • Catalogue No.:PA 30 62530

  • CAS :

    35654-56-9

  • Molecular Formula : C11H10ClNO2

  • Molecular Weight : 223.66

stdClass Object
(
    [pname] => Cabozantinib Nitro Analog
    [catalogue_number] => PA 30 62540
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 326.3
    [form] => C17H14N2O5
    [cas] => 190728-24-6
    [pslug] => 190728-24-6-cabozantinib-nitro-analog-pa3062540
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PA 30 62540

Cabozantinib Nitro Analog


  • Catalogue No.:PA 30 62540

  • CAS :

    190728-24-6

  • Molecular Formula : C17H14N2O5

  • Molecular Weight : 326.3

stdClass Object
(
    [pname] => Cabozantinib Amine Analog
    [catalogue_number] => PA 30 62550
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 296.32
    [form] => C17H16N2O3
    [cas] => 190728-25-7
    [pslug] => 190728-25-7-cabozantinib-amine-analog-pa3062550
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PA 30 62550

Cabozantinib Amine Analog


  • Catalogue No.:PA 30 62550

  • CAS :

    190728-25-7

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.32

stdClass Object
(
    [pname] => Cabozantinib Carboxylic Acid Analog
    [catalogue_number] => PA 30 62560
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 408.4
    [form] => C22H20N2O6
    [cas] => NA
    [pslug] => cabozantinib-carboxylic-acid-analog-pa3062560
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PA 30 62560

Cabozantinib Carboxylic Acid Analog


  • Catalogue No.:PA 30 62560

  • CAS :

    NA

  • Molecular Formula : C22H20N2O6

  • Molecular Weight : 408.4

stdClass Object
(
    [pname] => Cabozantinib Methyl Ester Analog
    [catalogue_number] => PA 30 62570
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 422.43
    [form] => C23H22N2O6
    [cas] => NA
    [pslug] => cabozantinib-methyl-ester-analog-pa3062570
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PA 30 62570

Cabozantinib Methyl Ester Analog


  • Catalogue No.:PA 30 62570

  • CAS :

    NA

  • Molecular Formula : C23H22N2O6

  • Molecular Weight : 422.43

stdClass Object
(
    [pname] => Cabozantinib Ethyl Ester Analog
    [catalogue_number] => PA 30 62580
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 436.46
    [form] => C24H24N2O6
    [cas] => NA
    [pslug] => cabozantinib-ethyl-ester-analog-pa3062580
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PA 30 62580

Cabozantinib Ethyl Ester Analog


  • Catalogue No.:PA 30 62580

  • CAS :

    NA

  • Molecular Formula : C24H24N2O6

  • Molecular Weight : 436.46

stdClass Object
(
    [pname] => Cabozantinib L-Malate Salt
    [catalogue_number] => PA 30 62590
    [category_ids] => 121,82,80,78,71,70
    [chemical_name] => 
    [weight] => 635.59
    [form] => C32H30FN3O10
    [cas] => 1140909-48-3
    [pslug] => 1140909-48-3-cabozantinib-l-malate-salt-pa3062590
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PA 30 62590

Cabozantinib L-Malate Salt


  • Catalogue No.:PA 30 62590

  • CAS :

    1140909-48-3

  • Molecular Formula : C32H30FN3O10

  • Molecular Weight : 635.59

stdClass Object
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    [pname] => 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid
    [catalogue_number] => PA 30 62600
    [category_ids] => ,80,79,89,71,
    [chemical_name] => 
    [weight] => 223.2
    [form] => C11H10FNO3
    [cas] => 849217-48-7
    [pslug] => 849217-48-7-1-4-fluorophenyl-carbamoyl-cyclopropanecarboxylic-acid-pa3062600
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PA 30 62600

1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid


  • Catalogue No.:PA 30 62600

  • CAS :

    849217-48-7

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

stdClass Object
(
    [pname] => N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
    [catalogue_number] => PA 30 62610
    [category_ids] => ,80,79,89,71,78,82,70,
    [chemical_name] => 
    [weight] => 314.31
    [form] => C17H15FN2O3
    [cas] => 849217-60-3
    [pslug] => 849217-60-3-n-4-fluorophenyl-n-4-hydroxyphenyl-cyclopropane-1-1-dicarboxamide-pa3062610
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PA 30 62610

N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 62610

  • CAS :

    849217-60-3

  • Molecular Formula : C17H15FN2O3

  • Molecular Weight : 314.31

stdClass Object
(
    [pname] => N1,N2-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)oxalamide
    [catalogue_number] => PA 30 62620
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 646.65
    [form] => C36H30N4O8
    [cas] => NA
    [pslug] => n1-n2-bis-4-6-7-dimethoxyquinolin-4-yl-oxy-phenyl-oxalamide-pa3062620
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PA 30 62620

N1,N2-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)oxalamide


  • Catalogue No.:PA 30 62620

  • CAS :

    NA

  • Molecular Formula : C36H30N4O8

  • Molecular Weight : 646.65

stdClass Object
(
    [pname] => Cabozantinib-d4
    [catalogue_number] => PA STI 089396
    [category_ids] => ,98,79,80,71,78,70,82,89,
    [chemical_name] => 
    [weight] => 505.54
    [form] => C28H20D4FN3O5
    [cas] => 1802168-53-1
    [pslug] => 1802168-53-1-cabozantinib-d4-pasti089396
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PA STI 089396

Cabozantinib-d4


  • Catalogue No.:PA STI 089396

  • CAS :

    1802168-53-1

  • Molecular Formula : C28H20D4FN3O5

  • Molecular Weight : 505.54

stdClass Object
(
    [pname] => N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine
    [catalogue_number] => PA 30 0621022
    [category_ids] => ,75,76,79,80,71,78,82,
    [chemical_name] => 
    [weight] => 483.52
    [form] => C28H25N3O5
    [cas] => NA
    [pslug] => n-4-6-7-dimethoxyquinolin-4-yl-oxy-phenyl-6-7-dimethoxyquinolin-4-amine-pa300621022
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PA 30 0621022

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine


  • Catalogue No.:PA 30 0621022

  • CAS :

    NA

  • Molecular Formula : C28H25N3O5

  • Molecular Weight : 483.52

stdClass Object
(
    [pname] => (E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide
    [catalogue_number] => PA 30 0621032
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 295.25
    [form] => C12H13N3O6
    [cas] => NA
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PA 30 0621032

(E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide


  • Catalogue No.:PA 30 0621032

  • CAS :

    NA

  • Molecular Formula : C12H13N3O6

  • Molecular Weight : 295.25

stdClass Object
(
    [pname] => 4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutyl (Z)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carbimidate
    [catalogue_number] => PA 30 0621033
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 1003.03
    [form] => C56H48F2N6O10
    [cas] => NA
    [pslug] => 4-4-6-7-dimethoxyquinolin-4-yl-oxy-phenyl-amino-3-4-fluorophenyl-carbamoyl-4-oxobutyl-z-n-4-6-7-dimethoxyquinolin-4-yl-oxy-phenyl-1-4-fluorophenyl-carbamoyl-cyclopropane-1-carbimidate-pa300621033
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PA 30 0621033

4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutyl (Z)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carbimidate


  • Catalogue No.:PA 30 0621033

  • CAS :

    NA

  • Molecular Formula : C56H48F2N6O10

  • Molecular Weight : 1003.03

stdClass Object
(
    [pname] => 5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
    [catalogue_number] => PA 30 0621034
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 307.3
    [form] => C15H17NO6
    [cas] => 213699-53-7
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PA 30 0621034

5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione


  • Catalogue No.:PA 30 0621034

  • CAS :

    213699-53-7

  • Molecular Formula : C15H17NO6

  • Molecular Weight : 307.3