darunavir

Heterocycles - A second-generation protease inhibitor, it is used for the treatment of HIV infections. It is administered along with ritonavir or cobicistat, to decrease metabolism and increase concentration.. Reference standards of Darunavir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Darunavir
    [catalogue_number] => PA 04 06000
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => 206361-99-1
    [pslug] => 206361-99-1-darunavir-api-pa0406000
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PA 04 06000
PA 04 06000

Darunavir


  • Catalogue No.:PA 04 06000

  • CAS :

    206361-99-1

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir O-β-D-Glucuronide
    [catalogue_number] => PA 04 06520
    [category_ids] => ,79,80,95,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 723.79
    [form] => C33H45N3O13S
    [cas] => 1159613-25-8
    [pslug] => 1159613-25-8-darunavir-o-beta-d-glucuronide-pa0406520
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PA 04 06520
PA 04 06520

Darunavir O-β-D-Glucuronide


  • Catalogue No.:PA 04 06520

  • CAS :

    1159613-25-8

  • Molecular Formula : C33H45N3O13S

  • Molecular Weight : 723.79

stdClass Object
(
    [pname] => (3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl Acetate
    [catalogue_number] => PA 04 06530
    [category_ids] => ,69,71,70,
    [chemical_name] => 
    [weight] => 172.18
    [form] => C8H12O4
    [cas] => 162020-29-3
    [pslug] => 162020-29-3-3s-3ar-6as-hexahydrofuro-2-3-b-furan-3-yl-acetate-pa0406530
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PA 04 06530
PA 04 06530

(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl Acetate


  • Catalogue No.:PA 04 06530

  • CAS :

    162020-29-3

  • Molecular Formula : C8H12O4

  • Molecular Weight : 172.18

stdClass Object
(
    [pname] => (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl-4-(N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenylcarbamate
    [catalogue_number] => PA 04 06540
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => NA
    [pslug] => 3r-3as-6ar-hexahydrofuro-2-3-b-furan-3-yl-4-n-2r-3s-3-amino-2-hydroxy-4-phenylbutyl-n-isobutylsulfamoyl-phenylcarbamate-pa0406540
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PA 04 06540
PA 04 06540

(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl-4-(N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenylcarbamate


  • Catalogue No.:PA 04 06540

  • CAS :

    NA

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => [(3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate
    [catalogue_number] => PA 04 06550
    [category_ids] => ,69,71,70,
    [chemical_name] => 
    [weight] => 271.22
    [form] => C11H13NO7
    [cas] => 253265-97-3
    [pslug] => 253265-97-3-3r-3as-6ar-hydroxyhexahydrofuro-2-3-b-furanyl-succinimidyl-carbonate-pa0406550
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PA 04 06550
PA 04 06550

[(3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate


  • Catalogue No.:PA 04 06550

  • CAS :

    253265-97-3

  • Molecular Formula : C11H13NO7

  • Molecular Weight : 271.22

stdClass Object
(
    [pname] => (3aS,4S,6aR)-Tetrahydro-4-methoxyfuro[3,4-b]furan-2(3H)-one
    [catalogue_number] => PA 04 06560
    [category_ids] => ,69,71,75,70,
    [chemical_name] => 
    [weight] => 158.15
    [form] => C7H10O4
    [cas] => 866594-60-7
    [pslug] => 866594-60-7-3as-4s-6ar-tetrahydro-4-methoxyfuro-3-4-b-furan-2-3h-one-pa0406560
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PA 04 06560
PA 04 06560

(3aS,4S,6aR)-Tetrahydro-4-methoxyfuro[3,4-b]furan-2(3H)-one


  • Catalogue No.:PA 04 06560

  • CAS :

    866594-60-7

  • Molecular Formula : C7H10O4

  • Molecular Weight : 158.15

stdClass Object
(
    [pname] => Darunavir Amine Dimer Impurity
    [catalogue_number] => PA 04 06590
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 965.19
    [form] => C48H64N6O11S2
    [cas] => NA
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PA 04 06590
PA 04 06590

Darunavir Amine Dimer Impurity


  • Catalogue No.:PA 04 06590

  • CAS :

    NA

  • Molecular Formula : C48H64N6O11S2

  • Molecular Weight : 965.19

stdClass Object
(
    [pname] => Darunavir Furan Dimer Impurity
    [catalogue_number] => PA 04 06600
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 703.8
    [form] => C34H45N3O11S
    [cas] => NA
    [pslug] => darunavir-furan-dimer-impurity-pa0406600
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PA 04 06600
PA 04 06600

Darunavir Furan Dimer Impurity


  • Catalogue No.:PA 04 06600

  • CAS :

    NA

  • Molecular Formula : C34H45N3O11S

  • Molecular Weight : 703.8

stdClass Object
(
    [pname] => Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
    [catalogue_number] => PA 04 06610
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 867.09
    [form] => C43H58N6O9S2
    [cas] => NA
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PA 04 06610
PA 04 06610

Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate


  • Catalogue No.:PA 04 06610

  • CAS :

    NA

  • Molecular Formula : C43H58N6O9S2

  • Molecular Weight : 867.09

stdClass Object
(
    [pname] => Darunavir Ethanolate
    [catalogue_number] => PA 04 06650
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 593.73
    [form] => C29H43N3O8S
    [cas] => 635728-49-3
    [pslug] => 635728-49-3-darunavir-ethanolate-pa0406650
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PA 04 06650
PA 04 06650

Darunavir Ethanolate


  • Catalogue No.:PA 04 06650

  • CAS :

    635728-49-3

  • Molecular Formula : C29H43N3O8S

  • Molecular Weight : 593.73

stdClass Object
(
    [pname] => Darunavir Carbamic Acid Impurity
    [catalogue_number] => PA 04 06660
    [category_ids] => ,80,71,78,70,82,79,88,
    [chemical_name] => 
    [weight] => 435.54
    [form] => C21H29N3O5S
    [cas] => 1526916-56-2
    [pslug] => 1526916-56-2-darunavir-carbamic-acid-impurity-pa0406660
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PA 04 06660
PA 04 06660

Darunavir Carbamic Acid Impurity


  • Catalogue No.:PA 04 06660

  • CAS :

    1526916-56-2

  • Molecular Formula : C21H29N3O5S

  • Molecular Weight : 435.54

stdClass Object
(
    [pname] => 4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide
    [catalogue_number] => PA 04 06670
    [category_ids] => ,88,82,80,79,71,70,78,
    [chemical_name] => 
    [weight] => 417.52
    [form] => C21H27N3O4S
    [cas] => 1418639-27-6
    [pslug] => 1418639-27-6-4-amino-n-2-methylpropyl-n-4s-5r-2-oxo-4-phenylmethyl-5-oxazolidinyl-methyl-benzenesulfonamide-pa0406670
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PA 04 06670
PA 04 06670

4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide


  • Catalogue No.:PA 04 06670

  • CAS :

    1418639-27-6

  • Molecular Formula : C21H27N3O4S

  • Molecular Weight : 417.52

stdClass Object
(
    [pname] => Darunavir-d9
    [catalogue_number] => PA STI 024400
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 556.72
    [form] => C27H28D9N3O7S
    [cas] => 1133378-37-6
    [pslug] => 1133378-37-6-darunavir-d9-pasti024400
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PA STI 024400
PA STI 024400

Darunavir-d9


  • Catalogue No.:PA STI 024400

  • CAS :

    1133378-37-6

  • Molecular Formula : C27H28D9N3O7S

  • Molecular Weight : 556.72

stdClass Object
(
    [pname] => (3S,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol
    [catalogue_number] => PA 04 06840
    [category_ids] => ,69,71,75,70,
    [chemical_name] => 
    [weight] => 130.14
    [form] => C6H10O3
    [cas] => 252873-50-0
    [pslug] => 252873-50-0-3s-3as-6ar-hexahydrofuro-2-3-b-furan-3-ol-pa0406840
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PA 04 06840
PA 04 06840

(3S,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol


  • Catalogue No.:PA 04 06840

  • CAS :

    252873-50-0

  • Molecular Formula : C6H10O3

  • Molecular Weight : 130.14

stdClass Object
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    [weight] => 130.14
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PA 04 06850
PA 04 06850

(3R,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol


  • Catalogue No.:PA 04 06850

  • CAS :

    252873-00-0

  • Molecular Formula : C6H10O3

  • Molecular Weight : 130.14

stdClass Object
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    [pname] => (3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol
    [catalogue_number] => PA 04 06860
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    [weight] => 130.14
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    [cas] => 156928-10-8
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PA 04 06860
PA 04 06860

(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol


  • Catalogue No.:PA 04 06860

  • CAS :

    156928-10-8

  • Molecular Formula : C6H10O3

  • Molecular Weight : 130.14

stdClass Object
(
    [pname] => Di-tert-butyl ((2S,2'S,3R,3'R)-(isobutylazanediyl)bis(3-hydroxy-1-phenylbutane-4,2-diyl))dicarbamate
    [catalogue_number] => PA 04 0061035
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    [weight] => 599.81
    [form] => C34H53N3O6
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PA 04 0061035
PA 04 0061035

Di-tert-butyl ((2S,2'S,3R,3'R)-(isobutylazanediyl)bis(3-hydroxy-1-phenylbutane-4,2-diyl))dicarbamate


  • Catalogue No.:PA 04 0061035

  • CAS :

    2307745-62-4

  • Molecular Formula : C34H53N3O6

  • Molecular Weight : 599.81

stdClass Object
(
    [pname] => Tert-butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate
    [catalogue_number] => PA 04 0061036
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    [chemical_name] => 
    [weight] => 299.8
    [form] => C15H22ClNO3
    [cas] => 165727-45-7
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PA 04 0061036
PA 04 0061036

Tert-butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate


  • Catalogue No.:PA 04 0061036

  • CAS :

    165727-45-7

  • Molecular Formula : C15H22ClNO3

  • Molecular Weight : 299.8

stdClass Object
(
    [pname] => N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-(methylamino)benzenesulfonamide
    [catalogue_number] => PA 04 0061037
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    [chemical_name] => 
    [weight] => 405.56
    [form] => C21H31N3O3S
    [cas] => 2765293-23-8
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PA 04 0061037
PA 04 0061037

N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-(methylamino)benzenesulfonamide


  • Catalogue No.:PA 04 0061037

  • CAS :

    2765293-23-8

  • Molecular Formula : C21H31N3O3S

  • Molecular Weight : 405.56

stdClass Object
(
    [pname] => (2R,3S)-3-Amino-1-(isobutylamino)-4-phenylbutan-2-ol Hydrochloride
    [catalogue_number] => PA 04 0061038
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 272.82
    [form] => C14H25ClN2O
    [cas] => NA
    [pslug] => 2r-3s-3-amino-1-isobutylamino-4-phenylbutan-2-ol-hydrochloride-pa040061038
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PA 04 0061038
PA 04 0061038

(2R,3S)-3-Amino-1-(isobutylamino)-4-phenylbutan-2-ol Hydrochloride


  • Catalogue No.:PA 04 0061038

  • CAS :

    NA

  • Molecular Formula : C14H25ClN2O

  • Molecular Weight : 272.82

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