Erlotinib-Impurities | Pharmaffiliates

erlotinib

An orally active tyrosine kinase inhibitor, Erlotinib is an anti cancer drug. It acts on the epidermal growth factor receptor (EGFR) and it is used for the treatment of several types of cancer like lung cancer, pancreatic cancer etc. Reference standards of Erlotinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Erlotinib - API Standards 
    [catalogue_number] => PA 05 14000
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 393.44
    [form] => C22H23N3O4
    [cas] => 183321-74-6
    [pslug] => 183321-74-6-erlotinib-api-pa0514000
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PA 05 14000

Erlotinib - API Standards


  • Catalogue No.:PA 05 14000

  • CAS :

    183321-74-6

  • Molecular Formula : C22H23N3O4

  • Molecular Weight : 393.44

stdClass Object
(
    [pname] => Erlotinib O-Desmethyl Metabolite (M14)
    [catalogue_number] => PA 05 14510
    [category_ids] => ,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 379.41
    [form] => C21H21N3O4
    [cas] => 183321-86-0
    [pslug] => 183321-86-0-erlotinib-o-desmethyl-metabolite-m14-pa0514510
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PA 05 14510

Erlotinib O-Desmethyl Metabolite (M14)


  • Catalogue No.:PA 05 14510

  • CAS :

    183321-86-0

  • Molecular Formula : C21H21N3O4

  • Molecular Weight : 379.41

stdClass Object
(
    [pname] => Didesmethyl Erlotinib Hydrochloride Salt
    [catalogue_number] => PA 05 14530
    [category_ids] => ,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 401.84
    [form] => C20H20ClN3O4
    [cas] => 183320-12-9
    [pslug] => 183320-12-9-didesmethyl-erlotinib-hydrochloride-salt-pa0514530
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PA 05 14530

Didesmethyl Erlotinib Hydrochloride Salt


  • Catalogue No.:PA 05 14530

  • CAS :

    183320-12-9

  • Molecular Formula : C20H20ClN3O4

  • Molecular Weight : 401.84

stdClass Object
(
    [pname] => Erlotinib Carboxylic Acid (M6)
    [catalogue_number] => PA 05 14540
    [category_ids] => ,70,71,78,82,
    [chemical_name] => 
    [weight] => 427.45
    [form] => C22H25N3O6
    [cas] => 882420-21-5
    [pslug] => 882420-21-5-erlotinib-carboxylic-acid-m6-pa0514540
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PA 05 14540

Erlotinib Carboxylic Acid (M6)


  • Catalogue No.:PA 05 14540

  • CAS :

    882420-21-5

  • Molecular Formula : C22H25N3O6

  • Molecular Weight : 427.45

stdClass Object
(
    [pname] => Erlotinib Hydroxy Metabolite
    [catalogue_number] => PA 05 14550
    [category_ids] => 82,78,71,70
    [chemical_name] => 
    [weight] => 409.44
    [form] => C22H23N3O5
    [cas] => 882420-22-6
    [pslug] => 882420-22-6-erlotinib-hydroxy-metabolite-pa0514550
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PA 05 14550

Erlotinib Hydroxy Metabolite


  • Catalogue No.:PA 05 14550

  • CAS :

    882420-22-6

  • Molecular Formula : C22H23N3O5

  • Molecular Weight : 409.44

stdClass Object
(
    [pname] => 6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride
    [catalogue_number] => PA 05 14630
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 434.32
    [form] => C21H21Cl2N3O3
    [cas] => 183320-04-9
    [pslug] => 183320-04-9-6-o-desmethoxyethyl-6-o-chloroethyl-erlotinib-hydrochloride-pa0514630
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PA 05 14630

6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride


  • Catalogue No.:PA 05 14630

  • CAS :

    183320-04-9

  • Molecular Formula : C21H21Cl2N3O3

  • Molecular Weight : 434.32

stdClass Object
(
    [pname] => 7-O-Desmethoxy-7-O-chloroethyl Erlotinib Hydrochloride
    [catalogue_number] => PA 05 14640
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 434.32
    [form] => C21H21Cl2N3O3
    [cas] => 183320-19-6
    [pslug] => 183320-19-6-7-o-desmethoxy-7-o-chloroethyl-erlotinib-hydrochloride-pa0514640
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PA 05 14640

7-O-Desmethoxy-7-O-chloroethyl Erlotinib Hydrochloride


  • Catalogue No.:PA 05 14640

  • CAS :

    183320-19-6

  • Molecular Formula : C21H21Cl2N3O3

  • Molecular Weight : 434.32

stdClass Object
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    [pname] => 7-(2'-Desmethyl) Erlotinib
    [catalogue_number] => PA 05 14650
    [category_ids] => ,70,71,74,78,79,80,81,82,117,
    [chemical_name] => 
    [weight] => 379.41
    [form] => C21H21N3O4
    [cas] => 183320-29-8
    [pslug] => 183320-29-8-7-2-desmethyl-erlotinib-pa0514650
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PA 05 14650

7-(2'-Desmethyl) Erlotinib


  • Catalogue No.:PA 05 14650

  • CAS :

    183320-29-8

  • Molecular Formula : C21H21N3O4

  • Molecular Weight : 379.41

stdClass Object
(
    [pname] => Desmethyl Erlotinib Hydrochloride
    [catalogue_number] => PA 05 14660
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 415.87
    [form] => C21H22ClN3O4
    [cas] => 183320-51-6
    [pslug] => 183320-51-6-desmethyl-erlotinib-hydrochloride-pa0514660
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PA 05 14660

Desmethyl Erlotinib Hydrochloride


  • Catalogue No.:PA 05 14660

  • CAS :

    183320-51-6

  • Molecular Formula : C21H22ClN3O4

  • Molecular Weight : 415.87

stdClass Object
(
    [pname] => Erlotinib-3-vinyl Hydrochloride
    [catalogue_number] => PA 05 14680
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 431.91
    [form] => C22H26ClN3O4
    [cas] => 1624294-38-7
    [pslug] => 1624294-38-7-erlotinib-3-vinyl-hydrochloride-pa0514680
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PA 05 14680

Erlotinib-3-vinyl Hydrochloride


  • Catalogue No.:PA 05 14680

  • CAS :

    1624294-38-7

  • Molecular Formula : C22H26ClN3O4

  • Molecular Weight : 431.91

stdClass Object
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    [pname] => 6,7-Bis(2-methoxyethoxy)-N-(3-ethylphenyl)-N-(2-methoxyethyl)-quinazoline-4-amine
    [catalogue_number] => PA 05 14710
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 455.55
    [form] => C25H33N3O5
    [cas] => NA
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PA 05 14710

6,7-Bis(2-methoxyethoxy)-N-(3-ethylphenyl)-N-(2-methoxyethyl)-quinazoline-4-amine


  • Catalogue No.:PA 05 14710

  • CAS :

    NA

  • Molecular Formula : C25H33N3O5

  • Molecular Weight : 455.55

stdClass Object
(
    [pname] => Tetrahydro Erlotinib
    [catalogue_number] => PA 05 14720
    [category_ids] => 117,82,81,80,79,78,74,71,70
    [chemical_name] => 
    [weight] => 397.47
    [form] => C22H27N3O4
    [cas] => 299912-61-1
    [pslug] => 299912-61-1-tetrahydro-erlotinib-pa0514720
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PA 05 14720

Tetrahydro Erlotinib


  • Catalogue No.:PA 05 14720

  • CAS :

    299912-61-1

  • Molecular Formula : C22H27N3O4

  • Molecular Weight : 397.47

stdClass Object
(
    [pname] => 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester
    [catalogue_number] => PA 05 14740
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 313.35
    [form] => C15H23NO6
    [cas] => 179688-27-8
    [pslug] => 179688-27-8-2-amino-4-5-bis-2-methoxyethoxy-benzoic-acid-ethyl-ester-pa0514740
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PA 05 14740

2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester


  • Catalogue No.:PA 05 14740

  • CAS :

    179688-27-8

  • Molecular Formula : C15H23NO6

  • Molecular Weight : 313.35

stdClass Object
(
    [pname] => Ethyl 3,4-bis(2-methoxyethoxy)benzoate
    [catalogue_number] => PA 05 14770
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 298.34
    [form] => C15H22O6
    [cas] => 183322-16-9
    [pslug] => 183322-16-9-ethyl-3-4-bis-2-methoxyethoxy-benzoate-pa0514770
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PA 05 14770

Ethyl 3,4-bis(2-methoxyethoxy)benzoate


  • Catalogue No.:PA 05 14770

  • CAS :

    183322-16-9

  • Molecular Formula : C15H22O6

  • Molecular Weight : 298.34

stdClass Object
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    [pname] => 2-Amino-4,5-bis(2-methoxyethoxy)benzamide
    [catalogue_number] => PA 05 14780
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 284.31
    [form] => C13H20N2O5
    [cas] => 236750-62-2
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PA 05 14780

2-Amino-4,5-bis(2-methoxyethoxy)benzamide


  • Catalogue No.:PA 05 14780

  • CAS :

    236750-62-2

  • Molecular Formula : C13H20N2O5

  • Molecular Weight : 284.31

stdClass Object
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    [pname] => 3-Ethynylaniline Hydrochloride
    [catalogue_number] => PA 05 14790
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 153.61
    [form] => C8H8ClN
    [cas] => 207226-02-6
    [pslug] => 207226-02-6-3-ethynylaniline-hydrochloride-pa0514790
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PA 05 14790

3-Ethynylaniline Hydrochloride


  • Catalogue No.:PA 05 14790

  • CAS :

    207226-02-6

  • Molecular Formula : C8H8ClN

  • Molecular Weight : 153.61

stdClass Object
(
    [pname] => (E)-N'-(2-cyano-4,5-bis(2-methoxyethoxy)phenyl)-N,N-dimethylformimidamide
    [catalogue_number] => PA 05 14800
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 321.37
    [form] => C16H23N3O4
    [cas] => 950596-59-5
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PA 05 14800

(E)-N'-(2-cyano-4,5-bis(2-methoxyethoxy)phenyl)-N,N-dimethylformimidamide


  • Catalogue No.:PA 05 14800

  • CAS :

    950596-59-5

  • Molecular Formula : C16H23N3O4

  • Molecular Weight : 321.37

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    [catalogue_number] => PA 05 14810
    [category_ids] => ,79,80,74,71,81,78,70,82,117,
    [chemical_name] => 
    [weight] => 293.32
    [form] => C14H19N3O4
    [cas] => 1417161-98-8
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PA 05 14810

6,7-Bis(2-methoxyethoxy)quinazolin-4-amine


  • Catalogue No.:PA 05 14810

  • CAS :

    1417161-98-8

  • Molecular Formula : C14H19N3O4

  • Molecular Weight : 293.32

stdClass Object
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    [pname] => Ethyl 2-amino-4,5-bis(2-methoxyethoxy)-benzoate Hydrochloride
    [catalogue_number] => PA 05 14820
    [category_ids] => ,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 349.81
    [form] => C15H24ClNO6
    [cas] => 183322-17-0
    [pslug] => 183322-17-0-ethyl-2-amino-4-5-bis-2-methoxyethoxy-benzoate-hydrochloride-pa0514820
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PA 05 14820

Ethyl 2-amino-4,5-bis(2-methoxyethoxy)-benzoate Hydrochloride


  • Catalogue No.:PA 05 14820

  • CAS :

    183322-17-0

  • Molecular Formula : C15H24ClNO6

  • Molecular Weight : 349.81

stdClass Object
(
    [pname] => 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester-d6 Hydrochloride
    [catalogue_number] => PA STI 005390
    [category_ids] => 98,71,70,78,82
    [chemical_name] => 
    [weight] => 355.84
    [form] => C15H18D6ClNO6
    [cas] => NA
    [pslug] => 2-amino-4-5-bis-2-methoxyethoxy-benzoic-acid-ethyl-ester-d6-hydrochloride-pasti005390
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PA STI 005390

2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester-d6 Hydrochloride


  • Catalogue No.:PA STI 005390

  • CAS :

    NA

  • Molecular Formula : C15H18D6ClNO6

  • Molecular Weight : 355.84

stdClass Object
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    [pname] => N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib Hydrochloride-D6
    [catalogue_number] => PA STI 027940
    [category_ids] => ,79,80,74,71,81,78,70,82,117,98,
    [chemical_name] => 
    [weight] => 490.81
    [form] => C20H17D6BrClN3O4
    [cas] => 2733154-09-9
    [pslug] => 2733154-09-9-n-3-desethynylphenyl-n-3-bromophenyl-erlotinib-hydrochloride-d6-pasti027940
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PA STI 027940

N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib Hydrochloride-D6


  • Catalogue No.:PA STI 027940

  • CAS :

    2733154-09-9

  • Molecular Formula : C20H17D6BrClN3O4

  • Molecular Weight : 490.81

stdClass Object
(
    [pname] => Erlotinib-d6 Hydrochloride
    [catalogue_number] => PA STI 037670
    [category_ids] => ,70,71,78,82,98,
    [chemical_name] => 
    [weight] => 435.93
    [form] => C22H18D6ClN3O4
    [cas] => 1189953-78-3
    [pslug] => 1189953-78-3-erlotinib-d6-hydrochloride-pasti037670
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PA STI 037670

Erlotinib-d6 Hydrochloride


  • Catalogue No.:PA STI 037670

  • CAS :

    1189953-78-3

  • Molecular Formula : C22H18D6ClN3O4

  • Molecular Weight : 435.93

stdClass Object
(
    [pname] => OSI-420-d4
    [catalogue_number] => PA STI 070430
    [category_ids] => ,80,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 383.43
    [form] => C21H17D4N3O4
    [cas] => 1216420-11-9
    [pslug] => 1216420-11-9-osi-420-d4-pasti070430
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PA STI 070430

OSI-420-d4


  • Catalogue No.:PA STI 070430

  • CAS :

    1216420-11-9

  • Molecular Formula : C21H17D4N3O4

  • Molecular Weight : 383.43

stdClass Object
(
    [pname] => Desmethyl Erlotinib Acetate
    [catalogue_number] => PA 05 14840
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 421.45
    [form] => C23H23N3O5
    [cas] => 183320-15-2
    [pslug] => 183320-15-2-desmethyl-erlotinib-acetate-pa0514840
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PA 05 14840

Desmethyl Erlotinib Acetate


  • Catalogue No.:PA 05 14840

  • CAS :

    183320-15-2

  • Molecular Formula : C23H23N3O5

  • Molecular Weight : 421.45