ezetimibe

Heterocycles - An anti-hyperlipidemic medication, it is used for cholesterol lowering that decreases the absorption of cholesterol in the small intestine. Ezetimibe is hence used for treating high cholesterol. Reference standards of Ezetimibe API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ezetimibe - Impurity F
    [catalogue_number] => PA 05 41510
    [category_ids] => ,89,82,81,80,78,75,71,70,
    [chemical_name] => 
    [weight] => 391.43
    [form] => C24H22FNO3
    [cas] => 302781-98-2
    [pslug] => 302781-98-2-ezetimibe-impurity-f-pa0541510
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PA 05 41510
PA 05 41510

Ezetimibe - Impurity F


  • Catalogue No.:PA 05 41510

  • CAS :

    302781-98-2

  • Molecular Formula : C24H22FNO3

  • Molecular Weight : 391.43

stdClass Object
(
    [pname] => (3'R,3R,4R)-Ezetimibe
    [catalogue_number] => PA 05 41520
    [category_ids] => ,80,71,81,78,70,82,89,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1593542-96-1
    [pslug] => 1593542-96-1-3r-3r-4r-ezetimibe-pa0541520
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PA 05 41520
PA 05 41520

(3'R,3R,4R)-Ezetimibe


  • Catalogue No.:PA 05 41520

  • CAS :

    1593542-96-1

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe - Impurity A
    [catalogue_number] => PA 05 41550
    [category_ids] => ,89,82,80,79,78,74,71,70,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1593543-07-7
    [pslug] => 1593543-07-7-ezetimibe-impurity-a-pa0541550
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PA 05 41550
PA 05 41550

Ezetimibe - Impurity A


  • Catalogue No.:PA 05 41550

  • CAS :

    1593543-07-7

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe - Impurity B
    [catalogue_number] => PA 05 41560
    [category_ids] => ,70,71,74,78,79,80,82,89,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 163380-16-3
    [pslug] => 163380-16-3-ezetimibe-impurity-b-pa0541560
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PA 05 41560
PA 05 41560

Ezetimibe - Impurity B


  • Catalogue No.:PA 05 41560

  • CAS :

    163380-16-3

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe - Impurity G
    [catalogue_number] => PA 05 41580
    [category_ids] => ,79,81,80,71,70,78,82,75,89,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1376614-99-1
    [pslug] => 1376614-99-1-ezetimibe-impurity-g-pa0541580
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PA 05 41580
PA 05 41580

Ezetimibe - Impurity G


  • Catalogue No.:PA 05 41580

  • CAS :

    1376614-99-1

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe Diol Impurity
    [catalogue_number] => PA 05 41590
    [category_ids] => ,80,71,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 413.46
    [form] => C24H25F2NO3
    [cas] => 1374250-08-4
    [pslug] => 1374250-08-4-ezetimibe-diol-impurity-pa0541590
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PA 05 41590
PA 05 41590

Ezetimibe Diol Impurity


  • Catalogue No.:PA 05 41590

  • CAS :

    1374250-08-4

  • Molecular Formula : C24H25F2NO3

  • Molecular Weight : 413.46

stdClass Object
(
    [pname] => Ezetimibe o-Fluoroaniline Analog
    [catalogue_number] => PA 05 41600
    [category_ids] => ,69,70,71,78,80,82,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 2191318-99-5
    [pslug] => 2191318-99-5-ezetimibe-o-fluoroaniline-analog-pa0541600
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PA 05 41600
PA 05 41600

Ezetimibe o-Fluoroaniline Analog


  • Catalogue No.:PA 05 41600

  • CAS :

    2191318-99-5

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => 4'-O-Benzyloxy (3S,4S)-Ezetimibe
    [catalogue_number] => PA 05 41610
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 499.55
    [form] => C31H27F2NO3
    [cas] => 1683564-73-9
    [pslug] => 1683564-73-9-4-o-benzyloxy-3s-4s-ezetimibe-pa0541610
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PA 05 41610
PA 05 41610

4'-O-Benzyloxy (3S,4S)-Ezetimibe


  • Catalogue No.:PA 05 41610

  • CAS :

    1683564-73-9

  • Molecular Formula : C31H27F2NO3

  • Molecular Weight : 499.55

stdClass Object
(
    [pname] => 4'-O-Benzyloxy Ezetimibe
    [catalogue_number] => PA 05 41630
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 499.55
    [form] => C31H27F2NO3
    [cas] => 163222-32-0
    [pslug] => 163222-32-0-4-o-benzyloxy-ezetimibe-pa0541630
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PA 05 41630
PA 05 41630

4'-O-Benzyloxy Ezetimibe


  • Catalogue No.:PA 05 41630

  • CAS :

    163222-32-0

  • Molecular Formula : C31H27F2NO3

  • Molecular Weight : 499.55

stdClass Object
(
    [pname] => (3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one
    [catalogue_number] => PA 05 41640
    [category_ids] => ,80,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 497.53
    [form] => C31H25F2NO3
    [cas] => 190595-65-4
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PA 05 41640
PA 05 41640

(3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one


  • Catalogue No.:PA 05 41640

  • CAS :

    190595-65-4

  • Molecular Formula : C31H25F2NO3

  • Molecular Weight : 497.53

stdClass Object
(
    [pname] => 3-Dehydroxy Ezetimibe
    [catalogue_number] => PA 05 41650
    [category_ids] => ,80,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 393.43
    [form] => C24H21F2NO2
    [cas] => 204589-58-2
    [pslug] => 204589-58-2-3-dehydroxy-ezetimibe-pa0541650
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PA 05 41650
PA 05 41650

3-Dehydroxy Ezetimibe


  • Catalogue No.:PA 05 41650

  • CAS :

    204589-58-2

  • Molecular Formula : C24H21F2NO2

  • Molecular Weight : 393.43

stdClass Object
(
    [pname] => Ezetimibe meta-Fluorobenzene Isomer
    [catalogue_number] => PA 05 41660
    [category_ids] => ,80,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => NA
    [pslug] => ezetimibe-meta-fluorobenzene-isomer-pa0541660
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PA 05 41660
PA 05 41660

Ezetimibe meta-Fluorobenzene Isomer


  • Catalogue No.:PA 05 41660

  • CAS :

    NA

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => (4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41670
    [category_ids] => ,80,78,70,82,89,79,71,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => 272778-12-8
    [pslug] => 272778-12-8-4s3-2r-5s-5-4-fluorophenyl-2-s-4-fluorophenyl-amino-4-trimethylsilyl-oxy-phenyl-methyl-1-oxo-5-trimethylsilyl-oxy-pentyl-4-phenyl-2-oxazolidinone-pa0541670
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PA 05 41670
PA 05 41670

(4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41670

  • CAS :

    272778-12-8

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => Ezetimibe - Impurity E
    [catalogue_number] => PA 05 41680
    [category_ids] => ,81,80,71,70,78,82,75,
    [chemical_name] => 
    [weight] => 391.43
    [form] => C24H22FNO3
    [cas] => 190595-66-5
    [pslug] => 190595-66-5-ezetimibe-impurity-e-pa0541680
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PA 05 41680
PA 05 41680

Ezetimibe - Impurity E


  • Catalogue No.:PA 05 41680

  • CAS :

    190595-66-5

  • Molecular Formula : C24H22FNO3

  • Molecular Weight : 391.43

stdClass Object
(
    [pname] => (E)-4-((Phenylimino)methyl)phenol
    [catalogue_number] => PA 05 41900
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 197.24
    [form] => C13H11NO
    [cas] => 2505-66-0
    [pslug] => 2505-66-0-e-4-phenylimino-methyl-phenol-pa0541900
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PA 05 41900
PA 05 41900

(E)-4-((Phenylimino)methyl)phenol


  • Catalogue No.:PA 05 41900

  • CAS :

    2505-66-0

  • Molecular Formula : C13H11NO

  • Molecular Weight : 197.24

stdClass Object
(
    [pname] => (S)-4-Phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41910
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 163.17
    [form] => C9H9NO2
    [cas] => 99395-88-7
    [pslug] => 99395-88-7-s-4-phenyl-2-oxazolidinone-pa0541910
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PA 05 41910
PA 05 41910

(S)-4-Phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41910

  • CAS :

    99395-88-7

  • Molecular Formula : C9H9NO2

  • Molecular Weight : 163.17

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    [pname] => (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41920
    [category_ids] => ,79,80,71,78,70,82,
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    [weight] => 572.6
    [form] => C33H30F2N2O5
    [cas] => 1185883-40-2
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PA 05 41920
PA 05 41920

(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41920

  • CAS :

    1185883-40-2

  • Molecular Formula : C33H30F2N2O5

  • Molecular Weight : 572.6

stdClass Object
(
    [pname] => (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41940
    [category_ids] => ,78,70,82,71,89,80,79,
    [chemical_name] => 
    [weight] => 644.78
    [form] => C36H38F2N2O5Si
    [cas] => NA
    [pslug] => s-3-2r-5s-5-4-fluorophenyl-2-s-4-fluorophenyl-amino-4-hydroxyphenyl-methyl-5-trimethylsilyl-oxy-pentanoyl-4-phenyloxazolidin-2-one-pa0541940
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PA 05 41940
PA 05 41940

(S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41940

  • CAS :

    NA

  • Molecular Formula : C36H38F2N2O5Si

  • Molecular Weight : 644.78

stdClass Object
(
    [pname] => (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(R)-[(3-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41950
    [category_ids] => ,78,70,82,71,89,80,79,
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    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => NA
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PA 05 41950
PA 05 41950

(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(R)-[(3-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41950

  • CAS :

    NA

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => (S)-3-((2R,5R)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41960
    [category_ids] => ,78,70,82,71,89,80,79,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => 1809031-15-9
    [pslug] => 1809031-15-9-s-3-2r-5r-5-4-fluorophenyl-2-s-4-fluorophenyl-amino-4-trimethylsilyl-oxy-phenyl-methyl-5-trimethylsilyl-oxy-pentanoyl-4-phenyloxazolidin-2-one-pa0541960
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PA 05 41960
PA 05 41960

(S)-3-((2R,5R)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41960

  • CAS :

    1809031-15-9

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => Ezetimibe Triol Impurity
    [catalogue_number] => PA 05 41970
    [category_ids] => ,78,70,82,71,89,80,
    [chemical_name] => 
    [weight] => 572.61
    [form] => C33H30F2N2O5
    [cas] => 2363086-22-8
    [pslug] => 2363086-22-8-ezetimibe-triol-impurity-pa0541970
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PA 05 41970
PA 05 41970

Ezetimibe Triol Impurity


  • Catalogue No.:PA 05 41970

  • CAS :

    2363086-22-8

  • Molecular Formula : C33H30F2N2O5

  • Molecular Weight : 572.61

stdClass Object
(
    [pname] => 4-O-Methylphenyl Ezetimibe-d4 Ketone
    [catalogue_number] => PA STI 062700
    [category_ids] => ,80,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 501.56
    [form] => C31H21D4F2NO3
    [cas] => NA
    [pslug] => 4-o-methylphenyl-ezetimibe-d4-ketone-pasti062700
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PA STI 062700
PA STI 062700

4-O-Methylphenyl Ezetimibe-d4 Ketone


  • Catalogue No.:PA STI 062700

  • CAS :

    NA

  • Molecular Formula : C31H21D4F2NO3

  • Molecular Weight : 501.56

stdClass Object
(
    [pname] => Ezetimibe Tetrahydropyran-d4 Impurity
    [catalogue_number] => PA STI 040540
    [category_ids] => ,79,80,69,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 413.45
    [form] => C24H17D4F2NO3
    [cas] => NA
    [pslug] => ezetimibe-tetrahydropyran-d4-impurity-pasti040540
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PA STI 040540
PA STI 040540

Ezetimibe Tetrahydropyran-d4 Impurity


  • Catalogue No.:PA STI 040540

  • CAS :

    NA

  • Molecular Formula : C24H17D4F2NO3

  • Molecular Weight : 413.45

stdClass Object
(
    [pname] => (3R)-N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide
    [catalogue_number] => PA 05 0411057
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 2468151-76-8
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PA 05 0411057
PA 05 0411057

(3R)-N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide


  • Catalogue No.:PA 05 0411057

  • CAS :

    2468151-76-8

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => (5S)-N,5-Bis(4-fluorophenyl)-5-hydroxy-2-(4-hydroxybenzyl)pentanamide
    [catalogue_number] => PA 05 0411058
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 411.45
    [form] => C24H23F2NO3
    [cas] => 2933154-47-1
    [pslug] => 2933154-47-1-5s-n-5-bis-4-fluorophenyl-5-hydroxy-2-4-hydroxybenzyl-pentanamide-pa050411058
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PA 05 0411058
PA 05 0411058

(5S)-N,5-Bis(4-fluorophenyl)-5-hydroxy-2-(4-hydroxybenzyl)pentanamide


  • Catalogue No.:PA 05 0411058

  • CAS :

    2933154-47-1

  • Molecular Formula : C24H23F2NO3

  • Molecular Weight : 411.45

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