ivabradine hydrochloride
Ivabradine Hydrochloride is used for the symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm who cannot take beta blockers. It is marketed under the trade name Corlanor. Reference standards of Ivabradine Hydrochloride API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Ivabradine Hydrochloride - API Standards
Catalogue No.:PA 09 24000
Molecular Formula : C27H37ClN2O5
Molecular Weight : 505.05
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(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride
Catalogue No.:PA 09 24650
Molecular Formula : C12H18ClNO2
Molecular Weight : 243.73
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[catalogue_number] => PA 09 24720
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3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one
Catalogue No.:PA 09 24720
Molecular Formula : C15H18ClNO3
Molecular Weight : 295.76
stdClass Object
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[pname] => Hydroxy Ivabradine
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[weight] => 279.33
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Catalogue No.:PA 09 24570
Molecular Formula : C15H21NO4
Molecular Weight : 279.33
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[catalogue_number] => PA 09 24580
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[weight] => 468.59
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Catalogue No.:PA 09 24580
Molecular Formula : C27H36N2O5
Molecular Weight : 468.59
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(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine
Catalogue No.:PA 09 24590
Molecular Formula : C11H15NO2
Molecular Weight : 193.24
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(7R)-3,4-dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride
Catalogue No.:PA 09 24600
Molecular Formula : C12H18ClNO2
Molecular Weight : 243.73
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[weight] => 283.32
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N-(2,2-Dimethoxyethyl)-2-(3,4-dimethoxyphenyl)acetamide
Catalogue No.:PA 09 24610
Molecular Formula : C14H21NO5
Molecular Weight : 283.32
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[pname] => Ivabradine R-Isomer Hydrochloride
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Ivabradine R-Isomer Hydrochloride
Catalogue No.:PA 09 24620
Molecular Formula : C27H37ClN2O5
Molecular Weight : 505.05
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[weight] => 519.03
[form] => C27H35ClN2O6
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2-Oxo-ivabradine Hydrochloride
Catalogue No.:PA 09 24630
Molecular Formula : C27H35ClN2O6
Molecular Weight : 519.03
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[pname] => (R)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine
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[weight] => 207.27
[form] => C12H17NO2
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(R)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine
Catalogue No.:PA 09 24660
Molecular Formula : C12H17NO2
Molecular Weight : 207.27
stdClass Object
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[weight] => 243.73
[form] => C12H18ClNO2
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(RS)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine
Catalogue No.:PA 09 24670
Molecular Formula : C12H18ClNO2
Molecular Weight : 243.73
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7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
Catalogue No.:PA 09 24710
Molecular Formula : C12H13NO3
Molecular Weight : 219.24
stdClass Object
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[weight] => 486.61
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(S)-2-(2-(2-((3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)acetic Acid
Catalogue No.:PA 09 24730
Molecular Formula : C27H38N2O6
Molecular Weight : 486.61
stdClass Object
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[weight] => 483.58
[form] => C27H35N2O6+
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(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-4-hydroxy-7,8-dimethoxy-5-oxo-2,5-dihydro-1H-benzo[d]azepin-3-ium
Catalogue No.:PA 09 24740
Molecular Formula : C27H35N2O6+
Molecular Weight : 483.58
stdClass Object
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[pname] => (S)-3,3'-((((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)azanediyl)bis(propane-3,1-diyl))bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one) Hydrochloride
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[weight] => 752.34
[form] => C41H54ClN3O8
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(S)-3,3'-((((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)azanediyl)bis(propane-3,1-diyl))bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one) Hydrochloride
Catalogue No.:PA 09 24770
Molecular Formula : C41H54ClN3O8
Molecular Weight : 752.34
stdClass Object
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[pname] => 2-Oxo-Ivabradine
[catalogue_number] => PA 09 0241010
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[weight] => 482.58
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Catalogue No.:PA 09 0241010
Molecular Formula : C27H34N2O6
Molecular Weight : 482.58