nilotinib

Heterocycles - Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Nilotinib - Impurity C
    [catalogue_number] => PA 14 64520
    [category_ids] => ,80,79,71,
    [chemical_name] => 
    [weight] => 151.16
    [form] => C8H9NO2
    [cas] => 2458-12-0
    [pslug] => 2458-12-0-nilotinib-impurity-c-pa1464520
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PA 14 64520
PA 14 64520

Nilotinib - Impurity C

  • Catalogue No.:PA 14 64520

  • CAS :

    2458-12-0

  • Molecular Formula : C8H9NO2

  • Molecular Weight : 151.16

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stdClass Object
(
    [pname] => 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
    [catalogue_number] => PA 14 64540
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 271.2
    [form] => C11H8F3N3O2
    [cas] => 916975-92-3
    [pslug] => 916975-92-3-4-methyl-1-3-nitro-5-trifluoromethyl-phenyl-1h-imidazole-pa1464540
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PA 14 64540
PA 14 64540

4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole

  • Catalogue No.:PA 14 64540

  • CAS :

    916975-92-3

  • Molecular Formula : C11H8F3N3O2

  • Molecular Weight : 271.2

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Details 
stdClass Object
(
    [pname] => Nilotinib - Impurity H (Hydrochloride Salt)
    [catalogue_number] => PA 14 64550
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 565.98
    [form] => C28H23ClF3N7O
    [cas] => NA
    [pslug] => -nilotinib-impurity-h-hydrochloride-salt-pa1464550
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PA 14 64550
PA 14 64550

Nilotinib - Impurity H (Hydrochloride Salt)

  • Catalogue No.:PA 14 64550

  • CAS :

    NA

  • Molecular Formula : C28H23ClF3N7O

  • Molecular Weight : 565.98

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stdClass Object
(
    [pname] => 3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 14 64560
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 563.96
    [form] => C28H21ClF3N7O
    [cas] => NA
    [pslug] => 3-4-chloro-6-pyridin-3-yl-pyrimidin-2-yl-amino-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-pa1464560
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PA 14 64560
PA 14 64560

3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 14 64560

  • CAS :

    NA

  • Molecular Formula : C28H21ClF3N7O

  • Molecular Weight : 563.96

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Details 
stdClass Object
(
    [pname] => Nilotinib - Impurity H (Freebase)
    [catalogue_number] => PA 14 64570
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 529.52
    [form] => C28H22F3N7O
    [cas] => 641571-15-5
    [pslug] => 641571-15-5-nilotinib-impurity-h-freebase-pa1464570
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PA 14 64570
PA 14 64570

Nilotinib - Impurity H (Freebase)

  • Catalogue No.:PA 14 64570

  • CAS :

    641571-15-5

  • Molecular Formula : C28H22F3N7O

  • Molecular Weight : 529.52

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stdClass Object
(
    [pname] => 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride
    [catalogue_number] => PA 14 64580
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 291.7
    [form] => C12H13ClF3N3
    [cas] => NA
    [pslug] => 3-4-ethyl-1h-imidazol-1-yl-5-trifluoromethyl-aniline-hydrochloride-pa1464580
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PA 14 64580
PA 14 64580

3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride

  • Catalogue No.:PA 14 64580

  • CAS :

    NA

  • Molecular Formula : C12H13ClF3N3

  • Molecular Weight : 291.7

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stdClass Object
(
    [pname] => 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
    [catalogue_number] => PA 14 64590
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 227.19
    [form] => C10H8F3N3
    [cas] => 943320-48-7
    [pslug] => 943320-48-7-3-1h-imidazol-1-yl-5-trifluoromethyl-aniline-pa1464590
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PA 14 64590
PA 14 64590

3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline

  • Catalogue No.:PA 14 64590

  • CAS :

    943320-48-7

  • Molecular Formula : C10H8F3N3

  • Molecular Weight : 227.19

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stdClass Object
(
    [pname] => 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
    [catalogue_number] => PA STI 062190
    [category_ids] => ,79,80,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 244.23
    [form] => C11H7D3F3N3
    [cas] => 1246815-34-8
    [pslug] => 1246815-34-8-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethylaniline-d3-pasti062190
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PA STI 062190
PA STI 062190

3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3

  • Catalogue No.:PA STI 062190

  • CAS :

    1246815-34-8

  • Molecular Formula : C11H7D3F3N3

  • Molecular Weight : 244.23

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stdClass Object
(
    [pname] => 3-Iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide-d3
    [catalogue_number] => PA STI 053340
    [category_ids] => ,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 488.26
    [form] => C19H12D3F3IN3O
    [cas] => 1246818-65-4
    [pslug] => 1246818-65-4-3-iodo-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-d3-pasti053340
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PA STI 053340
PA STI 053340

3-Iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide-d3

  • Catalogue No.:PA STI 053340

  • CAS :

    1246818-65-4

  • Molecular Formula : C19H12D3F3IN3O

  • Molecular Weight : 488.26

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stdClass Object
(
    [pname] => Nilotinib N-Oxide
    [catalogue_number] => PA 14 64600
    [category_ids] => ,85,83,75,76,78,82,71,70,80,
    [chemical_name] => 
    [weight] => 545.53
    [form] => C28H22F3N7O2
    [cas] => 1246817-85-5
    [pslug] => 1246817-85-5-nilotinib-n-oxide-pa1464600
    [latest_product] => 0
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PA 14 64600
PA 14 64600

Nilotinib N-Oxide

  • Catalogue No.:PA 14 64600

  • CAS :

    1246817-85-5

  • Molecular Formula : C28H22F3N7O2

  • Molecular Weight : 545.53

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Details 
stdClass Object
(
    [pname] => Nilotinib System Suitability Mixture
    [catalogue_number] => PA 14 0641001
    [category_ids] => ,80,71,76,75,93,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
    [pslug] => nilotinib-system-suitability-mixture-pa140641001
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PA 14 0641001
PA 14 0641001

Nilotinib System Suitability Mixture

  • Catalogue No.:PA 14 0641001

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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stdClass Object
(
    [pname] => Nilotinib N-Oxide (Pyrimidine N3-Oxide)
    [catalogue_number] => PA 14 0641034
    [category_ids] => ,75,76,78,82,71,70,
    [chemical_name] => 
    [weight] => 545.53
    [form] => C28H22F3N7O2
    [cas] => NA
    [pslug] => nilotinib-n-oxide-pyrimidine-n3-oxide-pa140641034
    [latest_product] => 0
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PA 14 0641034
PA 14 0641034

Nilotinib N-Oxide (Pyrimidine N3-Oxide)

  • Catalogue No.:PA 14 0641034

  • CAS :

    NA

  • Molecular Formula : C28H22F3N7O2

  • Molecular Weight : 545.53

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stdClass Object
(
    [pname] => Nilotinib N-Oxide (Pyrimidine N1-Oxide)
    [catalogue_number] => PA 14 0641035
    [category_ids] => ,75,76,78,82,71,70,
    [chemical_name] => 
    [weight] => 545.53
    [form] => C28H22F3N7O2
    [cas] => NA
    [pslug] => nilotinib-n-oxide-pyrimidine-n1-oxide-pa140641035
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PA 14 0641035
PA 14 0641035

Nilotinib N-Oxide (Pyrimidine N1-Oxide)

  • Catalogue No.:PA 14 0641035

  • CAS :

    NA

  • Molecular Formula : C28H22F3N7O2

  • Molecular Weight : 545.53

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Details 
stdClass Object
(
    [pname] => 5-Amino-2-methylbenzoic Acid
    [catalogue_number] => PA 14 0641036
    [category_ids] => ,75,76,78,82,71,70,
    [chemical_name] => 
    [weight] => 151.17
    [form] => C8H9NO2
    [cas] => 2840-04-2
    [pslug] => 2840-04-2-5-amino-2-methylbenzoic-acid-pa140641036
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PA 14 0641036
PA 14 0641036

5-Amino-2-methylbenzoic Acid

  • Catalogue No.:PA 14 0641036

  • CAS :

    2840-04-2

  • Molecular Formula : C8H9NO2

  • Molecular Weight : 151.17

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Details 
stdClass Object
(
    [pname] => 3-Amino-2-methylbenzoic Acid
    [catalogue_number] => PA 14 0641037
    [category_ids] => ,75,76,78,82,71,70,
    [chemical_name] => 
    [weight] => 151.17
    [form] => C8H9NO2
    [cas] => 52130-17-3
    [pslug] => 52130-17-3-3-amino-2-methylbenzoic-acid-pa140641037
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PA 14 0641037
PA 14 0641037

3-Amino-2-methylbenzoic Acid

  • Catalogue No.:PA 14 0641037

  • CAS :

    52130-17-3

  • Molecular Formula : C8H9NO2

  • Molecular Weight : 151.17

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Details 
stdClass Object
(
    [pname] => 3-Amino-5-methylbenzoic Acid
    [catalogue_number] => PA 14 0641038
    [category_ids] => ,75,76,78,82,71,70,
    [chemical_name] => 
    [weight] => 151.17
    [form] => C8H9NO2
    [cas] => 2305-37-5
    [pslug] => 2305-37-5-3-amino-5-methylbenzoic-acid-pa140641038
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PA 14 0641038
PA 14 0641038

3-Amino-5-methylbenzoic Acid

  • Catalogue No.:PA 14 0641038

  • CAS :

    2305-37-5

  • Molecular Formula : C8H9NO2

  • Molecular Weight : 151.17

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Details 
stdClass Object
(
    [pname] => 3-(2-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
    [catalogue_number] => PA 14 0641039
    [category_ids] => ,75,76,78,82,71,70,
    [chemical_name] => 
    [weight] => 255.24
    [form] => C12H12F3N3
    [cas] => 1260802-16-1
    [pslug] => 1260802-16-1-3-2-ethyl-1h-imidazol-1-yl-5-trifluoromethyl-aniline-pa140641039
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PA 14 0641039
PA 14 0641039

3-(2-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

  • Catalogue No.:PA 14 0641039

  • CAS :

    1260802-16-1

  • Molecular Formula : C12H12F3N3

  • Molecular Weight : 255.24

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stdClass Object
(
    [pname] => Ethyl 3-(3-(diaminomethylene)guanidino)-4-methylbenzoate
    [catalogue_number] => PA 14 0641040
    [category_ids] => ,75,76,78,82,71,70,
    [chemical_name] => 
    [weight] => 263.3
    [form] => C12H17N5O2
    [cas] => NA
    [pslug] => ethyl-3-3-diaminomethylene-guanidino-4-methylbenzoate-pa140641040
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PA 14 0641040
PA 14 0641040

Ethyl 3-(3-(diaminomethylene)guanidino)-4-methylbenzoate

  • Catalogue No.:PA 14 0641040

  • CAS :

    NA

  • Molecular Formula : C12H17N5O2

  • Molecular Weight : 263.3

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