nintedanib
A Nintedanib is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer. It is a small molecule kinase inhibitor. Reference standards of Nintedanib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[catalogue_number] => PA 14 54000
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[weight] => 539.62
[form] => C31H33N5O4
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Nintedanib - API Standards
Catalogue No.:PA 14 54000
Molecular Formula : C31H33N5O4
Molecular Weight : 539.62
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[pname] => Nintedanib Esylate - API Standards
[catalogue_number] => PA 14 54620
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[weight] => 649.76
[form] => C33H39N5O7S
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Nintedanib Esylate - API Standards
Catalogue No.:PA 14 54620
Molecular Formula : C33H39N5O7S
Molecular Weight : 649.76
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[catalogue_number] => PA 14 54510
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Catalogue No.:PA 14 54510
Molecular Formula : C31H33N5O4
Molecular Weight : 539.62
stdClass Object
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(Z)-3-(((4-(N-Methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid
stdClass Object
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[catalogue_number] => PA 14 54530
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(Z)-1-(2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1,4-dioxide
Catalogue No.:PA 14 54530
Molecular Formula : C31H33N5O6
Molecular Weight : 571.62
stdClass Object
(
[pname] => (Z)-Methyl 3-((methyl(4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
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(Z)-Methyl 3-((methyl(4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 54540
Molecular Formula : C32H35N5O4
Molecular Weight : 553.65
stdClass Object
(
[pname] => (Z)-Methyl 1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
[catalogue_number] => PA 14 54560
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(Z)-Methyl 1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 54560
Molecular Formula : C33H35N5O5
Molecular Weight : 581.66
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(Z)-Methyl 3-(((4-(N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 54570
Molecular Formula : C26H23N3O4
Molecular Weight : 441.48
stdClass Object
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[catalogue_number] => PA 14 54580
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(3Z,3'Z)-Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))bis(2-oxoindoline-6-carboxylate)
Catalogue No.:PA 14 54580
Molecular Formula : C56H52N8O8
Molecular Weight : 965.06
stdClass Object
(
[pname] => Methyl (3Z)-3-[({4-[2-(4-ethylpiperazin-1-yl)-N-methylacetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
[catalogue_number] => PA 14 54590
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[weight] => 553.65
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Methyl (3Z)-3-[({4-[2-(4-ethylpiperazin-1-yl)-N-methylacetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
Catalogue No.:PA 14 54590
Molecular Formula : C32H35N5O4
Molecular Weight : 553.65
stdClass Object
(
[pname] => (Z)-1-(2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1-oxide
[catalogue_number] => PA 14 54600
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[weight] => 555.62
[form] => C31H33N5O5
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(Z)-1-(2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1-oxide
Catalogue No.:PA 14 54600
Molecular Formula : C31H33N5O5
Molecular Weight : 555.62
stdClass Object
(
[pname] => Ethyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
[catalogue_number] => PA 14 54610
[category_ids] => 85,83,77,71,70,78,82
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[weight] => 553.65
[form] => C32H35N5O4
[cas] => 1139455-52-9
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Ethyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
Catalogue No.:PA 14 54610
Molecular Formula : C32H35N5O4
Molecular Weight : 553.65
stdClass Object
(
[pname] => Intedanib-d3
[catalogue_number] => PA STI 053200
[category_ids] => 98,82,79,78,71,70
[chemical_name] =>
[weight] => 542.64
[form] => C31H30D3N5O4
[cas] => 1624587-84-3
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Catalogue No.:PA STI 053200
Molecular Formula : C31H30D3N5O4
Molecular Weight : 542.64
stdClass Object
(
[pname] => Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxo-1-propionylindoline-6-carboxylate
[catalogue_number] => PA 14 0541035
[category_ids] => ,71,78,70,82,
[chemical_name] =>
[weight] => 595.7
[form] => C34H37N5O5
[cas] => 2097505-01-4
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Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxo-1-propionylindoline-6-carboxylate
stdClass Object
(
[pname] => N-nitroso-N-desmethylnintedanib
[catalogue_number] => PA 14 0541039
[category_ids] => ,70,71,78,79,82,162,
[chemical_name] =>
[weight] => 554.61
[form] => C30H30N6O5
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N-nitroso-N-desmethylnintedanib
Catalogue No.:PA 14 0541039
Molecular Formula : C30H30N6O5
Molecular Weight : 554.61
stdClass Object
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[pname] => Nintedanib Acetamide Impurity
[catalogue_number] => PA 14 0541040
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[chemical_name] =>
[weight] => 248.33
[form] => C13H20N4O
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Nintedanib Acetamide Impurity
Catalogue No.:PA 14 0541040
Molecular Formula : C13H20N4O
Molecular Weight : 248.33
stdClass Object
(
[pname] => Nintedanib 4-Nitrophenyl 2-(4-Nitroso)
[catalogue_number] => PA 14 0541042
[category_ids] => ,70,71,78,79,82,162,
[chemical_name] =>
[weight] => 307.31
[form] => C13H17N5O4
[cas] => 2490403-92-2
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Nintedanib 4-Nitrophenyl 2-(4-Nitroso)
Catalogue No.:PA 14 0541042
Molecular Formula : C13H17N5O4
Molecular Weight : 307.31
stdClass Object
(
[pname] => Methyl 1-acetyl-2-oxoindoline-6-carboxylate
[catalogue_number] => PA 14 0541043
[category_ids] => ,79,71,78,70,82,
[chemical_name] =>
[weight] => 233.22
[form] => C12H11NO4
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Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 0541043
Molecular Formula : C12H11NO4
Molecular Weight : 233.22
stdClass Object
(
[pname] => Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))bis(1-acetyl-2-oxoindoline-6-carboxylate)
[catalogue_number] => PA 14 0541044
[category_ids] => ,79,71,78,82,
[chemical_name] =>
[weight] => 1049.15
[form] => C60H56N8O10
[cas] => 2410649-55-5
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Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))bis(1-acetyl-2-oxoindoline-6-carboxylate)
Catalogue No.:PA 14 0541044
Molecular Formula : C60H56N8O10
Molecular Weight : 1049.15
stdClass Object
(
[pname] => 1-(2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1,4-dioxide
[catalogue_number] => PA 14 0541045
[category_ids] => ,79,71,78,70,82,
[chemical_name] =>
[weight] => 571.63
[form] => C31H33N5O6
[cas] => 2734676-68-5
[pslug] => 2734676-68-5-1-2-4-6-methoxycarbonyl-2-oxoindolin-3-ylidene-phenyl-methyl-amino-phenyl-methyl-amino-2-oxoethyl-4-methylpiperazine-1-4-dioxide-pa140541045
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1-(2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1,4-dioxide
Catalogue No.:PA 14 0541045
Molecular Formula : C31H33N5O6
Molecular Weight : 571.63
stdClass Object
(
[pname] => N-(4-Aminophenyl)-2-chloro-N-methylacetamide
[catalogue_number] => PA 14 0541046
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[chemical_name] =>
[weight] => 198.65
[form] => C9H11ClN2O
[cas] => 855860-75-2
[pslug] => 855860-75-2-n-4-aminophenyl-2-chloro-n-methylacetamide-pa140541046
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N-(4-Aminophenyl)-2-chloro-N-methylacetamide
Catalogue No.:PA 14 0541046
Molecular Formula : C9H11ClN2O
Molecular Weight : 198.65
stdClass Object
(
[pname] => Methyl 4-chloro-3-nitrobenzoate
[catalogue_number] => PA 14 0541047
[category_ids] => ,82,78,76,79,71,78,70,82,75,70,
[chemical_name] =>
[weight] => 215.59
[form] => C8H6ClNO4
[cas] => 14719-83-6
[pslug] => 14719-83-6-methyl-4-chloro-3-nitrobenzoate-pa140541047
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Methyl 4-chloro-3-nitrobenzoate
Catalogue No.:PA 14 0541047
Molecular Formula : C8H6ClNO4
Molecular Weight : 215.59
stdClass Object
(
[pname] => N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
[catalogue_number] => PA 14 0541048
[category_ids] => ,82,78,76,79,71,78,70,82,75,70,
[chemical_name] =>
[weight] => 292.34
[form] => C14H20N4O3
[cas] => 1139453-98-7
[pslug] => 1139453-98-7-n-methyl-2-4-methylpiperazin-1-yl-n-4-nitrophenyl-acetamide-pa140541048
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N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Catalogue No.:PA 14 0541048
Molecular Formula : C14H20N4O3
Molecular Weight : 292.34
stdClass Object
(
[pname] => Methyl 3-(((4-hydroxyphenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
[catalogue_number] => PA 14 0541049
[category_ids] => ,79,71,78,70,82,
[chemical_name] =>
[weight] => 386.41
[form] => C23H18N2O4
[cas] => 2519501-85-8
[pslug] => 2519501-85-8-methyl-3-4-hydroxyphenyl-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541049
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Methyl 3-(((4-hydroxyphenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 0541049
Molecular Formula : C23H18N2O4
Molecular Weight : 386.41