Olaparib

Heterocycles - Olaparib is used to treat ovarian cancer in people with a specific gene who have not improved or who have worsened after treatment with at least three other therapies.Reference standards of Olaparib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Olaparib
    [catalogue_number] => PA 15 70000
    [category_ids] => ,71,80,81,78,82,70,
    [chemical_name] => 
    [weight] => 434.47
    [form] => C24H23FN4O3
    [cas] => 763113-22-0
    [pslug] => 763113-22-0-olaparib-api-pa1570000
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PA 15 70000
PA 15 70000

Olaparib


  • Catalogue No.:PA 15 70000

  • CAS :

    763113-22-0

  • Molecular Formula : C24H23FN4O3

  • Molecular Weight : 434.47

stdClass Object
(
    [pname] => 4-((3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorophenyl)(2-oxopyrrolidin-1-yl)methyl)phthalazin-1(2H)-one
    [catalogue_number] => PA 15 0701027
    [category_ids] => ,75,76,80,71,81,78,82,
    [chemical_name] => 
    [weight] => 517.56
    [form] => C28H28FN5O4
    [cas] => NA
    [pslug] => 4-3-4-cyclopropanecarbonyl-piperazine-1-carbonyl-4-fluorophenyl-2-oxopyrrolidin-1-yl-methyl-phthalazin-1-2h-one-pa150701027
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PA 15 0701027
PA 15 0701027

4-((3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorophenyl)(2-oxopyrrolidin-1-yl)methyl)phthalazin-1(2H)-one


  • Catalogue No.:PA 15 0701027

  • CAS :

    NA

  • Molecular Formula : C28H28FN5O4

  • Molecular Weight : 517.56

stdClass Object
(
    [pname] => 4-(5-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-2-fluorobenzyl)phthalazin-1(2H)-one
    [catalogue_number] => PA 15 0701028
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 434.47
    [form] => C24H23FN4O3
    [cas] => NA
    [pslug] => 4-5-4-cyclopropanecarbonyl-piperazine-1-carbonyl-2-fluorobenzyl-phthalazin-1-2h-one-pa150701028
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PA 15 0701028
PA 15 0701028

4-(5-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-2-fluorobenzyl)phthalazin-1(2H)-one


  • Catalogue No.:PA 15 0701028

  • CAS :

    NA

  • Molecular Formula : C24H23FN4O3

  • Molecular Weight : 434.47

stdClass Object
(
    [pname] => 4-(2-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
    [catalogue_number] => PA 15 0701029
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 434.47
    [form] => C24H23FN4O3
    [cas] => NA
    [pslug] => 4-2-4-cyclopropanecarbonyl-piperazine-1-carbonyl-4-fluorobenzyl-phthalazin-1-2h-one-pa150701029
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PA 15 0701029
PA 15 0701029

4-(2-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one


  • Catalogue No.:PA 15 0701029

  • CAS :

    NA

  • Molecular Formula : C24H23FN4O3

  • Molecular Weight : 434.47

stdClass Object
(
    [pname] => 4-(4-Fluorobenzyl)phthalazin-1(2H)-one
    [catalogue_number] => PA 15 0701030
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 254.26
    [form] => C15H11FN2O
    [cas] => 120359-17-3
    [pslug] => 120359-17-3-4-4-fluorobenzyl-phthalazin-1-2h-one-pa150701030
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PA 15 0701030
PA 15 0701030

4-(4-Fluorobenzyl)phthalazin-1(2H)-one


  • Catalogue No.:PA 15 0701030

  • CAS :

    120359-17-3

  • Molecular Formula : C15H11FN2O

  • Molecular Weight : 254.26

stdClass Object
(
    [pname] => 4-(3-Bromo-4-fluorobenzyl)phthalazin-1(2H)-one
    [catalogue_number] => PA 15 0701031
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 333.16
    [form] => C15H10BrFN2O
    [cas] => 1062292-60-7
    [pslug] => 1062292-60-7-4-3-bromo-4-fluorobenzyl-phthalazin-1-2h-one-pa150701031
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PA 15 0701031
PA 15 0701031

4-(3-Bromo-4-fluorobenzyl)phthalazin-1(2H)-one


  • Catalogue No.:PA 15 0701031

  • CAS :

    1062292-60-7

  • Molecular Formula : C15H10BrFN2O

  • Molecular Weight : 333.16

stdClass Object
(
    [pname] => (4-Fluoro-1,3-phenylene)bis((4-(cyclopropanecarbonyl)piperazin-1-yl)methanone)
    [catalogue_number] => PA 15 0701032
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 456.52
    [form] => C24H29FN4O4
    [cas] => 2795135-26-9
    [pslug] => 2795135-26-9-4-fluoro-1-3-phenylene-bis-4-cyclopropanecarbonyl-piperazin-1-yl-methanone-pa150701032
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PA 15 0701032
PA 15 0701032

(4-Fluoro-1,3-phenylene)bis((4-(cyclopropanecarbonyl)piperazin-1-yl)methanone)


  • Catalogue No.:PA 15 0701032

  • CAS :

    2795135-26-9

  • Molecular Formula : C24H29FN4O4

  • Molecular Weight : 456.52

stdClass Object
(
    [pname] => 1-(Cyclopropylmethyl)-4-nitrosopiperazine
    [catalogue_number] => PA 15 0701034
    [category_ids] => ,79,80,71,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 169.23
    [form] => C8H15N3O
    [cas] => NA
    [pslug] => 1-cyclopropylmethyl-4-nitrosopiperazine-pa150701034
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PA 15 0701034
PA 15 0701034

1-(Cyclopropylmethyl)-4-nitrosopiperazine


  • Catalogue No.:PA 15 0701034

  • CAS :

    NA

  • Molecular Formula : C8H15N3O

  • Molecular Weight : 169.23

stdClass Object
(
    [pname] => 1-Methanesulfonyloxy-1,2,3-benzotriazole
    [catalogue_number] => PA 15 0701035
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 213.21
    [form] => C7H7N3O3S
    [cas] => 54769-22-1
    [pslug] => 54769-22-1-1-methanesulfonyloxy-1-2-3-benzotriazole-pa150701035
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PA 15 0701035
PA 15 0701035

1-Methanesulfonyloxy-1,2,3-benzotriazole


  • Catalogue No.:PA 15 0701035

  • CAS :

    54769-22-1

  • Molecular Formula : C7H7N3O3S

  • Molecular Weight : 213.21

stdClass Object
(
    [pname] => 4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-hydroxybenzyl)phthalazin-1(2H)-one
    [catalogue_number] => PA 15 0701036
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 432.48
    [form] => C24H24N4O4
    [cas] => NA
    [pslug] => 4-3-4-cyclopropanecarbonyl-piperazine-1-carbonyl-4-hydroxybenzyl-phthalazin-1-2h-one-pa150701036
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PA 15 0701036
PA 15 0701036

4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-hydroxybenzyl)phthalazin-1(2H)-one


  • Catalogue No.:PA 15 0701036

  • CAS :

    NA

  • Molecular Formula : C24H24N4O4

  • Molecular Weight : 432.48

stdClass Object
(
    [pname] => 4-(3-(4-Nitrosopiperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
    [catalogue_number] => PA 15 0701037
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 377.4
    [form] => C20H19N5O3
    [cas] => NA
    [pslug] => 4-3-4-nitrosopiperazine-1-carbonyl-benzyl-phthalazin-1-2h-one-pa150701037
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PA 15 0701037
PA 15 0701037

4-(3-(4-Nitrosopiperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one


  • Catalogue No.:PA 15 0701037

  • CAS :

    NA

  • Molecular Formula : C20H19N5O3

  • Molecular Weight : 377.4

stdClass Object
(
    [pname] => 2-Fluoro-5-formylbenzonitrile
    [catalogue_number] => PA 15 0701052
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 149.12
    [form] => C8H4FNO
    [cas] => 218301-22-5
    [pslug] => 218301-22-5-2-fluoro-5-formylbenzonitrile-pa150701052
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PA 15 0701052
PA 15 0701052

2-Fluoro-5-formylbenzonitrile


  • Catalogue No.:PA 15 0701052

  • CAS :

    218301-22-5

  • Molecular Formula : C8H4FNO

  • Molecular Weight : 149.12

stdClass Object
(
    [pname] => Dimethyl (5-bromo-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
    [catalogue_number] => PA 15 0701053
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 321.06
    [form] => C10H10BrO5P
    [cas] => NA
    [pslug] => dimethyl-5-bromo-3-oxo-1-3-dihydroisobenzofuran-1-yl-phosphonate-pa150701053
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PA 15 0701053
PA 15 0701053

Dimethyl (5-bromo-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate


  • Catalogue No.:PA 15 0701053

  • CAS :

    NA

  • Molecular Formula : C10H10BrO5P

  • Molecular Weight : 321.06

stdClass Object
(
    [pname] => 3-Chlorophthalide
    [catalogue_number] => PA 15 0701054
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 168.58
    [form] => C8H5ClO2
    [cas] => 6295-21-2
    [pslug] => 6295-21-2-3-chlorophthalide-pa150701054
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PA 15 0701054
PA 15 0701054

3-Chlorophthalide


  • Catalogue No.:PA 15 0701054

  • CAS :

    6295-21-2

  • Molecular Formula : C8H5ClO2

  • Molecular Weight : 168.58

stdClass Object
(
    [pname] => Dimethyl (5-chloro-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
    [catalogue_number] => PA 15 0701055
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 276.61
    [form] => C10H10ClO5P
    [cas] => NA
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PA 15 0701055
PA 15 0701055

Dimethyl (5-chloro-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate


  • Catalogue No.:PA 15 0701055

  • CAS :

    NA

  • Molecular Formula : C10H10ClO5P

  • Molecular Weight : 276.61

stdClass Object
(
    [pname] => Cyclopropyl(4-ethylpiperazin-1-yl)methanone
    [catalogue_number] => PA 15 0701056
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 182.27
    [form] => C10H18N2O
    [cas] => 547698-14-6
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PA 15 0701056
PA 15 0701056

Cyclopropyl(4-ethylpiperazin-1-yl)methanone


  • Catalogue No.:PA 15 0701056

  • CAS :

    547698-14-6

  • Molecular Formula : C10H18N2O

  • Molecular Weight : 182.27

stdClass Object
(
    [pname] => Ethyl cyclopropanecarboxylate
    [catalogue_number] => PA 15 0701057
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 114.14
    [form] => C6H10O2
    [cas] => 4606-07-9
    [pslug] => 4606-07-9-ethyl-cyclopropanecarboxylate-pa150701057
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PA 15 0701057
PA 15 0701057

Ethyl cyclopropanecarboxylate


  • Catalogue No.:PA 15 0701057

  • CAS :

    4606-07-9

  • Molecular Formula : C6H10O2

  • Molecular Weight : 114.14

stdClass Object
(
    [pname] => (4-(5-((4-Chlorophthalazin-1-yl)methyl)-2-fluorobenzoyl)piperazin-1-yl)(cyclopropyl)methanone
    [catalogue_number] => PA 15 0701058
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 452.91
    [form] => C24H22ClFN4O2
    [cas] => NA
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PA 15 0701058
PA 15 0701058

(4-(5-((4-Chlorophthalazin-1-yl)methyl)-2-fluorobenzoyl)piperazin-1-yl)(cyclopropyl)methanone


  • Catalogue No.:PA 15 0701058

  • CAS :

    NA

  • Molecular Formula : C24H22ClFN4O2

  • Molecular Weight : 452.91

stdClass Object
(
    [pname] => (4-(5-((1H-Indol-3-yl)methyl)-2-fluorobenzoyl)piperazin-1-yl)(cyclopropyl)methanone
    [catalogue_number] => PA 15 0701059
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 405.47
    [form] => C24H24FN3O2
    [cas] => NA
    [pslug] => 4-5-1h-indol-3-yl-methyl-2-fluorobenzoyl-piperazin-1-yl-cyclopropyl-methanone-pa150701059
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PA 15 0701059
PA 15 0701059

(4-(5-((1H-Indol-3-yl)methyl)-2-fluorobenzoyl)piperazin-1-yl)(cyclopropyl)methanone


  • Catalogue No.:PA 15 0701059

  • CAS :

    NA

  • Molecular Formula : C24H24FN3O2

  • Molecular Weight : 405.47

stdClass Object
(
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    [catalogue_number] => PA 15 0701060
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 284.24
    [form] => C16H9FO4
    [cas] => 1831142-42-7
    [pslug] => 1831142-42-7-2-fluoro-5-3-oxoisobenzofuran-1-3h-ylidene-methyl-benzoic-acid-pa150701060
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PA 15 0701060
PA 15 0701060

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzoic Acid


  • Catalogue No.:PA 15 0701060

  • CAS :

    1831142-42-7

  • Molecular Formula : C16H9FO4

  • Molecular Weight : 284.24

stdClass Object
(
    [pname] => Dimethyl (5,7-dichloro-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
    [catalogue_number] => PA 15 0701063
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 311.05
    [form] => C10H9Cl2O5P
    [cas] => NA
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PA 15 0701063
PA 15 0701063

Dimethyl (5,7-dichloro-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate


  • Catalogue No.:PA 15 0701063

  • CAS :

    NA

  • Molecular Formula : C10H9Cl2O5P

  • Molecular Weight : 311.05

stdClass Object
(
    [pname] => 5-((7-Bromo-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-2-fluorobenzoic Acid
    [catalogue_number] => PA 15 0701064
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 377.17
    [form] => C16H10BrFN2O3
    [cas] => 1174044-56-4
    [pslug] => 1174044-56-4-5-7-bromo-4-oxo-3-4-dihydrophthalazin-1-yl-methyl-2-fluorobenzoic-acid-pa150701064
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PA 15 0701064
PA 15 0701064

5-((7-Bromo-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-2-fluorobenzoic Acid


  • Catalogue No.:PA 15 0701064

  • CAS :

    1174044-56-4

  • Molecular Formula : C16H10BrFN2O3

  • Molecular Weight : 377.17

stdClass Object
(
    [pname] => 5-((8-Chloro-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-2-fluorobenzoic Acid
    [catalogue_number] => PA 15 0701065
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 332.72
    [form] => C16H10ClFN2O3
    [cas] => 1174044-59-7
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PA 15 0701065
PA 15 0701065

5-((8-Chloro-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-2-fluorobenzoic Acid


  • Catalogue No.:PA 15 0701065

  • CAS :

    1174044-59-7

  • Molecular Formula : C16H10ClFN2O3

  • Molecular Weight : 332.72

stdClass Object
(
    [pname] => 5-((6,8-Dichloro-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-2-fluorobenzoic Acid
    [catalogue_number] => PA 15 0701066
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 367.16
    [form] => C16H9Cl2FN2O3
    [cas] => NA
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PA 15 0701066
PA 15 0701066

5-((6,8-Dichloro-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-2-fluorobenzoic Acid


  • Catalogue No.:PA 15 0701066

  • CAS :

    NA

  • Molecular Formula : C16H9Cl2FN2O3

  • Molecular Weight : 367.16

stdClass Object
(
    [pname] => 5,5'-(1-Hydroxy-2-oxoethane-1,2-diyl)bis(2-fluorobenzoic Acid)
    [catalogue_number] => PA 15 0701067
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 336.25
    [form] => C16H10F2O6
    [cas] => NA
    [pslug] => 5-5-1-hydroxy-2-oxoethane-1-2-diyl-bis-2-fluorobenzoic-acid-pa150701067
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PA 15 0701067
PA 15 0701067

5,5'-(1-Hydroxy-2-oxoethane-1,2-diyl)bis(2-fluorobenzoic Acid)


  • Catalogue No.:PA 15 0701067

  • CAS :

    NA

  • Molecular Formula : C16H10F2O6

  • Molecular Weight : 336.25

stdClass Object
(
    [pname] => 6,6'-Oxybis(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic Acid)
    [catalogue_number] => PA 15 0701068
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 574.55
    [form] => C32H22N4O7
    [cas] => NA
    [pslug] => 6-6-oxybis-3-4-oxo-3-4-dihydrophthalazin-1-yl-methyl-benzoic-acid-pa150701068
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PA 15 0701068
PA 15 0701068

6,6'-Oxybis(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic Acid)


  • Catalogue No.:PA 15 0701068

  • CAS :

    NA

  • Molecular Formula : C32H22N4O7

  • Molecular Weight : 574.55

stdClass Object
(
    [pname] => 5-((2-Carboxyphenyl)ethynyl)-2-fluorobenzoic Acid
    [catalogue_number] => PA 15 0701069
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 284.24
    [form] => C16H9FO4
    [cas] => 2447717-11-3
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PA 15 0701069
PA 15 0701069

5-((2-Carboxyphenyl)ethynyl)-2-fluorobenzoic Acid


  • Catalogue No.:PA 15 0701069

  • CAS :

    2447717-11-3

  • Molecular Formula : C16H9FO4

  • Molecular Weight : 284.24

stdClass Object
(
    [pname] => 1-(4-(Cyclopropanecarbonyl)piperazin-1-yl)-2,2,2-trifluoroethan-1-one
    [catalogue_number] => PA 15 0701082
    [category_ids] => ,70,71,78,80,82,
    [chemical_name] => 
    [weight] => 250.22
    [form] => C10H13F3N2O2
    [cas] => 1467759-67-6
    [pslug] => 1467759-67-6-1-4-cyclopropanecarbonyl-piperazin-1-yl-2-2-2-trifluoroethan-1-one-pa150701082
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PA 15 0701082
PA 15 0701082

1-(4-(Cyclopropanecarbonyl)piperazin-1-yl)-2,2,2-trifluoroethan-1-one


  • Catalogue No.:PA 15 0701082

  • CAS :

    1467759-67-6

  • Molecular Formula : C10H13F3N2O2

  • Molecular Weight : 250.22

stdClass Object
(
    [pname] => Olaparib Methoxy Derivative
    [catalogue_number] => PA 15 0701083
    [category_ids] => ,82,81,80,78,71,70,
    [chemical_name] => 
    [weight] => 446.51
    [form] => C25H26N4O4
    [cas] => NA
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PA 15 0701083
PA 15 0701083

Olaparib Methoxy Derivative


  • Catalogue No.:PA 15 0701083

  • CAS :

    NA

  • Molecular Formula : C25H26N4O4

  • Molecular Weight : 446.51

stdClass Object
(
    [pname] => 2-Fluoro-5-(3-hydroxy-1-oxo-1H-inden-2-yl)benzoic Acid
    [catalogue_number] => PA 15 0701084
    [category_ids] => ,82,81,80,78,71,70,
    [chemical_name] => 
    [weight] => 284.24
    [form] => C16H9FO4
    [cas] => 1831142-43-8
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PA 15 0701084

2-Fluoro-5-(3-hydroxy-1-oxo-1H-inden-2-yl)benzoic Acid


  • Catalogue No.:PA 15 0701084

  • CAS :

    1831142-43-8

  • Molecular Formula : C16H9FO4

  • Molecular Weight : 284.24

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