Osimertinib is used to treat locally advanced or metastatic non-small-cell lung cancer. It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor.Reference standards of Osimertinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => 3,3'-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) [catalogue_number] => PA 15 51510 [category_ids] => ,70,71,75,78,80,82, [chemical_name] => [weight] => 338.41 [form] => C22H18N4 [cas] => 2364486-24-6 [pslug] => 2364486-24-6-3-3-pyrimidine-2-4-diyl-bis-1-methyl-1h-indole-pa1551510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 15 51510
CAS :
Molecular Formula : C22H18N4
Molecular Weight : 338.41
stdClass Object ( [pname] => 3-(4-Chloropyrimidin-2-yl)-1-methyl-1H-indole [catalogue_number] => PA 15 51520 [category_ids] => ,70,71,75,78,80,82, [chemical_name] => [weight] => 243.69 [form] => C13H10ClN3 [cas] => 2364486-23-5 [pslug] => 2364486-23-5-3-4-chloropyrimidin-2-yl-1-methyl-1h-indole-pa1551520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 15 51520
Molecular Formula : C13H10ClN3
Molecular Weight : 243.69
stdClass Object ( [pname] => Osimertinib N-Oxide [catalogue_number] => PA 15 0511000 [category_ids] => 82,80,78,75,71,70 [chemical_name] => [weight] => 515.62 [form] => C28H33N7O3 [cas] => 2411395-22-5 [pslug] => 2411395-22-5-osimertinib-n-oxide-pa150511000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 15 0511000
Molecular Formula : C28H33N7O3
Molecular Weight : 515.62
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