ponatinib

Heterocycles - A multi-targeted tyrosine-kinase inhibitor, Ponatinib is used in treating chronic myeloid leukemia. Shows antiangiogenic and antineoplastic activities.Reference standards of Ponatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ponatinib
    [catalogue_number] => PA 16 91000
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 532.56
    [form] => C29H27F3N6O
    [cas] => 943319-70-8
    [pslug] => 943319-70-8-ponatinib-api-pa1691000
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PA 16 91000
PA 16 91000

Ponatinib


  • Catalogue No.:PA 16 91000

  • CAS :

    943319-70-8

  • Molecular Formula : C29H27F3N6O

  • Molecular Weight : 532.56

stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide
    [catalogue_number] => PA 16 91520
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 433.16
    [form] => C16H11F3INO2
    [cas] => 1638193-91-5
    [pslug] => 1638193-91-5-n-4-formyl-3-trifluoromethyl-phenyl-3-iodo-4-methylbenzamide-pa1691520
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PA 16 91520
PA 16 91520

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide


  • Catalogue No.:PA 16 91520

  • CAS :

    1638193-91-5

  • Molecular Formula : C16H11F3INO2

  • Molecular Weight : 433.16

stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide
    [catalogue_number] => PA 16 91530
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 448.4
    [form] => C24H15F3N4O2
    [cas] => 1638193-92-6
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PA 16 91530
PA 16 91530

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide


  • Catalogue No.:PA 16 91530

  • CAS :

    1638193-92-6

  • Molecular Formula : C24H15F3N4O2

  • Molecular Weight : 448.4

stdClass Object
(
    [pname] => 3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 91540
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 415.45
    [form] => C23H24F3N3O
    [cas] => 957147-18-1
    [pslug] => 957147-18-1-3-ethynyl-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa1691540
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PA 16 91540
PA 16 91540

3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 91540

  • CAS :

    957147-18-1

  • Molecular Formula : C23H24F3N3O

  • Molecular Weight : 415.45

stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
    [catalogue_number] => PA 16 0911002
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 277.28
    [form] => C16H11N3O2
    [cas] => 1300690-48-5
    [pslug] => 1300690-48-5-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzoic-acid-pa160911002
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PA 16 0911002
PA 16 0911002

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid


  • Catalogue No.:PA 16 0911002

  • CAS :

    1300690-48-5

  • Molecular Formula : C16H11N3O2

  • Molecular Weight : 277.28

stdClass Object
(
    [pname] => Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate
    [catalogue_number] => PA 16 0911003
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 291.31
    [form] => C17H13N3O2
    [cas] => 1356385-96-0
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PA 16 0911003
PA 16 0911003

Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate


  • Catalogue No.:PA 16 0911003

  • CAS :

    1356385-96-0

  • Molecular Formula : C17H13N3O2

  • Molecular Weight : 291.31

stdClass Object
(
    [pname] => 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911004
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 273.3
    [form] => C13H18F3N3
    [cas] => 694499-26-8
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PA 16 0911004
PA 16 0911004

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline


  • Catalogue No.:PA 16 0911004

  • CAS :

    694499-26-8

  • Molecular Formula : C13H18F3N3

  • Molecular Weight : 273.3

stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 0911006
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 547.54
    [form] => C28H24F3N7O2
    [cas] => NA
    [pslug] => 3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methyl-n-4-4-nitrosopiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911006
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PA 16 0911006
PA 16 0911006

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 0911006

  • CAS :

    NA

  • Molecular Formula : C28H24F3N7O2

  • Molecular Weight : 547.54

stdClass Object
(
    [pname] => 4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911007
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 288.27
    [form] => C12H15F3N4O
    [cas] => NA
    [pslug] => 4-4-nitrosopiperazin-1-yl-methyl-3-trifluoromethyl-aniline-pa160911007
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PA 16 0911007
PA 16 0911007

4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline


  • Catalogue No.:PA 16 0911007

  • CAS :

    NA

  • Molecular Formula : C12H15F3N4O

  • Molecular Weight : 288.27

stdClass Object
(
    [pname] => Ponatinib N-beta-D-Glucuronide
    [catalogue_number] => PA 16 0911008
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 789.61
    [form] => C35H36BrF3N6O7
    [cas] => NA
    [pslug] => ponatinib-n-beta-d-glucuronide-pa160911008
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PA 16 0911008
PA 16 0911008

Ponatinib N-beta-D-Glucuronide


  • Catalogue No.:PA 16 0911008

  • CAS :

    NA

  • Molecular Formula : C35H36BrF3N6O7

  • Molecular Weight : 789.61

stdClass Object
(
    [pname] => Methyl 3-iodo-4-methylbenzoate
    [catalogue_number] => PA 16 0911009
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 276.07
    [form] => C9H9IO2
    [cas] => 90347-66-3
    [pslug] => 90347-66-3-methyl-3-iodo-4-methylbenzoate-pa160911009
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PA 16 0911009
PA 16 0911009

Methyl 3-iodo-4-methylbenzoate


  • Catalogue No.:PA 16 0911009

  • CAS :

    90347-66-3

  • Molecular Formula : C9H9IO2

  • Molecular Weight : 276.07

stdClass Object
(
    [pname] => 7-((Triisopropylsilyl)ethynyl)-3H-imidazo[4,5-b]pyridine
    [catalogue_number] => PA 16 0911010
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 299.49
    [form] => C17H25N3Si
    [cas] => 2500888-31-1
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PA 16 0911010
PA 16 0911010

7-((Triisopropylsilyl)ethynyl)-3H-imidazo[4,5-b]pyridine


  • Catalogue No.:PA 16 0911010

  • CAS :

    2500888-31-1

  • Molecular Formula : C17H25N3Si

  • Molecular Weight : 299.49

stdClass Object
(
    [pname] => 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine
    [catalogue_number] => PA 16 0911011
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 215.33
    [form] => C11H13N3Si
    [cas] => 943320-60-3
    [pslug] => 943320-60-3-3-trimethylsilyl-ethynyl-imidazo-1-2-b-pyridazine-pa160911011
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PA 16 0911011
PA 16 0911011

3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine


  • Catalogue No.:PA 16 0911011

  • CAS :

    943320-60-3

  • Molecular Formula : C11H13N3Si

  • Molecular Weight : 215.33

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