Roflumilast is used in the prevention of lung attacks in severe COPD. It is a long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4).Reference standards of Roflumilast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => 5-Dechloro Roflumilast [catalogue_number] => PA 18 15510 [category_ids] => ,71,75,81,78,70,82, [chemical_name] => [weight] => 368.76 [form] => C17H15ClF2N2O3 [cas] => 1391053-75-0 [pslug] => 1391053-75-0-5-dechloro-roflumilast-pa1815510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15510
CAS :
Molecular Formula : C17H15ClF2N2O3
Molecular Weight : 368.76
stdClass Object ( [pname] => 3-O-Decyclopropyl Roflumilast [catalogue_number] => PA 18 15520 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 349.12 [form] => C13H8Cl2F2N2O3 [cas] => 1391052-76-8 [pslug] => 1391052-76-8-3-o-decyclopropyl-roflumilast-pa1815520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15520
Molecular Formula : C13H8Cl2F2N2O3
Molecular Weight : 349.12
stdClass Object ( [pname] => Roflumilast N-Oxide [catalogue_number] => PA 18 15530 [category_ids] => 82,81,78,76,75,71,70 [chemical_name] => [weight] => 419.21 [form] => C17H14Cl2F2N2O4 [cas] => 292135-78-5 [pslug] => 292135-78-5-roflumilast-n-oxide-pa1815530 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15530
Molecular Formula : C17H14Cl2F2N2O4
Molecular Weight : 419.21
stdClass Object ( [pname] => 4-Amino-3,5-dichloropyridine [catalogue_number] => PA 18 15550 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 163 [form] => C5H4Cl2N2 [cas] => 22889-78-7 [pslug] => 22889-78-7-4-amino-3-5-dichloropyridine-pa1815550 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15550
Molecular Formula : C5H4Cl2N2
Molecular Weight : 163
stdClass Object ( [pname] => 3,4-Di(cyclopropylmethoxy) Roflumilast [catalogue_number] => PA 18 15570 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 407.29 [form] => C20H20Cl2N2O3 [cas] => 1391052-24-6 [pslug] => 1391052-24-6-3-4-di-cyclopropylmethoxy-roflumilast-pa1815570 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15570
Molecular Formula : C20H20Cl2N2O3
Molecular Weight : 407.29
stdClass Object ( [pname] => 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast [catalogue_number] => PA 18 15580 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 403.21 [form] => C17H14Cl2F2N2O3 [cas] => 162401-43-6 [pslug] => 162401-43-6-4-cyclopropylmethoxy-3-difluoromethoxy-roflumilast-pa1815580 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15580
Molecular Formula : C17H14Cl2F2N2O3
Molecular Weight : 403.21
stdClass Object ( [pname] => 3,4-bis(Difluoromethoxy) Roflumilast [catalogue_number] => PA 18 15590 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 399.12 [form] => C14H8Cl2F4N2O3 [cas] => 162401-30-1 [pslug] => 162401-30-1-3-4-bis-difluoromethoxy-roflumilast-pa1815590 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15590
Molecular Formula : C14H8Cl2F4N2O3
Molecular Weight : 399.12
stdClass Object ( [pname] => 3-Cyclobutyl-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide [catalogue_number] => PA 18 15610 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 387.21 [form] => C17H14Cl2F2N2O2 [cas] => NA [pslug] => 3-cyclobutyl-n-3-5-dichloropyridin-4-yl-4-difluoromethoxy-benzamide-pa1815610 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15610
Molecular Formula : C17H14Cl2F2N2O2
Molecular Weight : 387.21
stdClass Object ( [pname] => 3-(But-3-en-1-yloxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide [catalogue_number] => PA 18 15620 [category_ids] => 80,71,75,70,78,82,81 [chemical_name] => [weight] => 403.21 [form] => C17H14Cl2F2N2O3 [cas] => 2368178-29-2 [pslug] => 3-but-3-en-1-yloxy-n-3-5-dichloropyridin-4-yl-4-difluoromethoxy-benzamide-pa1815620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15620
stdClass Object ( [pname] => 3,4-Di(cyclopropylmethoxy)-benzoic Acid [catalogue_number] => PA 18 15630 [category_ids] => 82,78,70,71,80 [chemical_name] => [weight] => 262.3 [form] => C15H18O4 [cas] => 1369851-30-8 [pslug] => 1369851-30-8-3-4-di-cyclopropylmethoxy-benzoic-acid-pa1815630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15630
Molecular Formula : C15H18O4
Molecular Weight : 262.3
stdClass Object ( [pname] => Roflumilast-d4 N-Oxide [catalogue_number] => PA STI 078310 [category_ids] => ,71,98,76,75,81,78,70,82, [chemical_name] => [weight] => 423.23 [form] => C17H10D4Cl2F2N2O4 [cas] => 1794760-31-8 [pslug] => 1794760-31-8-roflumilast-d4-n-oxide-pasti078310 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 078310
Molecular Formula : C17H10D4Cl2F2N2O4
Molecular Weight : 423.23
stdClass Object ( [pname] => 4-Amino-2,6-dichloropyridine [catalogue_number] => PA 18 15680 [category_ids] => ,79,80,71,85,83, [chemical_name] => [weight] => 163 [form] => C5H4Cl2N2 [cas] => 2587-02-2 [pslug] => 2587-02-2-4-amino-2-6-dichloropyridine-pa1815680 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15680
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