rosuvastatin
Heterocycles
- Rosuvastatin is used along with a proper diet to help lower bad cholesterol and fats and raise good cholesterol in the blood. It is sold under the trade name Crestor. It is available as a generic medication.Reference standards of Rosuvastatin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => 3-Oxo Rosuvastatin Sodium
[catalogue_number] => PA 18 20570
[category_ids] => ,71,70,78,70,82,88,
[chemical_name] =>
[weight] => 501.5
[form] => C22H25FN3NaO6S
[cas] => 1346606-28-7
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3-Oxo Rosuvastatin Sodium
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[pname] => tert-Butyl 2-((4S,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
[catalogue_number] => PA 18 20575
[category_ids] => ,89,88,82,78,71,70,
[chemical_name] =>
[weight] => 577.71
[form] => C29H40FN3O6S
[cas] => 1378943-63-5
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tert-Butyl 2-((4S,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
Catalogue No.:PA 18 20575
Molecular Formula : C29H40FN3O6S
Molecular Weight : 577.71
stdClass Object
(
[pname] => (S)-Methyl 3-hydroxy-5-oxo-6-(triphenylphosphoranylidene)hexanoate
[catalogue_number] => PA 18 20580
[category_ids] => ,80,71,70,78,70,82,72,
[chemical_name] =>
[weight] => 420.44
[form] => C25H25O4P
[cas] => NA
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(S)-Methyl 3-hydroxy-5-oxo-6-(triphenylphosphoranylidene)hexanoate
Catalogue No.:PA 18 20580
Molecular Formula : C25H25O4P
Molecular Weight : 420.44
stdClass Object
(
[pname] => tert-Butyl 2-((4S,6R)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
[catalogue_number] => PA 18 20585
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[weight] => 577.71
[form] => C29H40FN3O6S
[cas] => NA
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tert-Butyl 2-((4S,6R)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
Catalogue No.:PA 18 20585
Molecular Formula : C29H40FN3O6S
Molecular Weight : 577.71
stdClass Object
(
[pname] => (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid Methyl Ester
[catalogue_number] => PA 18 20640
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[weight] => 607.81
[form] => C29H42FN3O6SSi
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(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid Methyl Ester
Catalogue No.:PA 18 20640
Molecular Formula : C29H42FN3O6SSi
Molecular Weight : 607.81
stdClass Object
(
[pname] => 5-Oxorosuvastatin Methyl Ester
[catalogue_number] => PA 18 20650
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[weight] => 493.55
[form] => C23H28FN3O6S
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5-Oxorosuvastatin Methyl Ester
Catalogue No.:PA 18 20650
Molecular Formula : C23H28FN3O6S
Molecular Weight : 493.55
stdClass Object
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[pname] => 5-((3S,5R,E)-6-Carboxy-3,5-dihydroxyhex-1-en-1-yl)-6-(4-fluorophenyl)-4-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine 1-Oxide
[catalogue_number] => PA 18 20655
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[form] => C22H28FN3O7S
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5-((3S,5R,E)-6-Carboxy-3,5-dihydroxyhex-1-en-1-yl)-6-(4-fluorophenyl)-4-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine 1-Oxide
Catalogue No.:PA 18 20655
Molecular Formula : C22H28FN3O7S
Molecular Weight : 497.54
stdClass Object
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[pname] => Dihydro Rosuvastatin Calcium
[catalogue_number] => PA 18 20660
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[weight] => 1005.17
[form] => C44H58CaF2N6O12S2
[cas] => NA
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Dihydro Rosuvastatin Calcium
Catalogue No.:PA 18 20660
Molecular Formula : C44H58CaF2N6O12S2
Molecular Weight : 1005.17
stdClass Object
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[pname] => 5-((3S,5R,E)-6-Carboxy-3,5-dihydroxyhex-1-en-1-yl)-4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine 1-Oxide
[catalogue_number] => PA 18 20665
[category_ids] => ,79,80,69,71,70,78,70,82,88,89,
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[weight] => 497.54
[form] => C22H28FN3O7S
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5-((3S,5R,E)-6-Carboxy-3,5-dihydroxyhex-1-en-1-yl)-4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine 1-Oxide
Catalogue No.:PA 18 20665
Molecular Formula : C22H28FN3O7S
Molecular Weight : 497.54
stdClass Object
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[pname] => 3-Oxo Rosuvastatin Calcium
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[weight] => 479.52 + 1/2(40.08)
[form] => C22H26FN3O6S . 1/2Ca
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3-Oxo Rosuvastatin Calcium
Catalogue No.:PA 18 20670
Molecular Formula : C22H26FN3O6S . 1/2Ca
Molecular Weight : 479.52 + 1/2(40.08)
stdClass Object
(
[pname] => (3R,5S)-5-(3-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)oxiran-2-yl)-3,5-dihydroxypentanoic Acid
[catalogue_number] => PA 18 20675
[category_ids] => ,92,79,80,69,71,70,78,70,82,88,89,
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[weight] => 497.54
[form] => C22H28FN3O7S
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(3R,5S)-5-(3-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)oxiran-2-yl)-3,5-dihydroxypentanoic Acid
Catalogue No.:PA 18 20675
Molecular Formula : C22H28FN3O7S
Molecular Weight : 497.54
stdClass Object
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[pname] => Rosuvastatin Acid - Impurity N (Freebase)
[catalogue_number] => PA 18 20680
[category_ids] => ,88,82,80,78,75,71,70,
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[weight] => 463.52
[form] => C22H26FN3O5S
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Rosuvastatin Acid - Impurity N (Freebase)
Catalogue No.:PA 18 20680
Molecular Formula : C22H26FN3O5S
Molecular Weight : 463.52
stdClass Object
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[pname] => N-(4-(4-Fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-2-hydroxy-N,2-dimethylpropane-1-sulfonamide
[catalogue_number] => PA 18 20685
[category_ids] => ,71,70,78,82,89,88,80,75,
[chemical_name] =>
[weight] => 409.48
[form] => C19H24FN3O4S
[cas] => 2101546-09-0
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N-(4-(4-Fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-2-hydroxy-N,2-dimethylpropane-1-sulfonamide
Catalogue No.:PA 18 20685
Molecular Formula : C19H24FN3O4S
Molecular Weight : 409.48
stdClass Object
(
[pname] => Rosuvastatin (6S)-Anhydro Lactone Impurity
[catalogue_number] => PA 18 20690
[category_ids] => ,70,71,75,78,80,82,88,89,
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[weight] => 445.51
[form] => C22H24FN3O4S
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Rosuvastatin (6S)-Anhydro Lactone Impurity
Catalogue No.:PA 18 20690
Molecular Formula : C22H24FN3O4S
Molecular Weight : 445.51
stdClass Object
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[catalogue_number] => PA 18 20695
[category_ids] => ,75,80,82,78,70,71,
[chemical_name] =>
[weight] => 258.31
[form] => C13H22O5
[cas] => 125517-63-7
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tert-Butyl [(4RS,6SR)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Catalogue No.:PA 18 20695
Molecular Formula : C13H22O5
Molecular Weight : 258.31
stdClass Object
(
[pname] => Rosuvastatin Dehydro Triene
[catalogue_number] => PA 18 20700
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[weight] => 445.51
[form] => C22H24FN3O4S
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Rosuvastatin Dehydro Triene
Catalogue No.:PA 18 20700
Molecular Formula : C22H24FN3O4S
Molecular Weight : 445.51
stdClass Object
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[pname] => Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylthio)-2,5-dihydropyrimidine-5-carboxylate
[catalogue_number] => PA 18 20720
[category_ids] => ,70,71,78,79,80,82,88,92,
[chemical_name] =>
[weight] => 322.4
[form] => C16H19FN2O2S
[cas] => 849470-67-3
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Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylthio)-2,5-dihydropyrimidine-5-carboxylate
stdClass Object
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[catalogue_number] => PA 18 20730
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[weight] => 352.38
[form] => C16H17FN2O4S
[cas] => 799842-06-1
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Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylsulfonyl)pyrimidine-5-carboxylate
Catalogue No.:PA 18 20730
Molecular Formula : C16H17FN2O4S
Molecular Weight : 352.38
stdClass Object
(
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Methyl 6-(4-Fluorophenyl)-4-isopropyl-2-methylthio-1,4-dihydropyrimidine-5-carboxylate
stdClass Object
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[chemical_name] =>
[weight] => 303.33
[form] => C16H18FN3O2
[cas] => 160009-36-9
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Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylamino)pyrimidine-5-carboxylate
Catalogue No.:PA 18 20770
Molecular Formula : C16H18FN3O2
Molecular Weight : 303.33
stdClass Object
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[weight] => 381.42
[form] => C17H20FN3O4S
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Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methylsulfonyl)amino]pyrimidine-5-carboxylate
Catalogue No.:PA 18 20780
Molecular Formula : C17H20FN3O4S
Molecular Weight : 381.42
stdClass Object
(
[pname] => N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
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[weight] => 353.41
[form] => C16H20FN3O3S
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N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
Catalogue No.:PA 18 20790
Molecular Formula : C16H20FN3O3S
Molecular Weight : 353.41
stdClass Object
(
[pname] => (4R,6S)-6-(Chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-Dimethylethyl Ester
[catalogue_number] => PA 18 20830
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[chemical_name] =>
[weight] => 278.77
[form] => C13H23ClO4
[cas] => 154026-94-5
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(4R,6S)-6-(Chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-Dimethylethyl Ester
Catalogue No.:PA 18 20830
Molecular Formula : C13H23ClO4
Molecular Weight : 278.77
stdClass Object
(
[pname] => Rosuvastatin Formyl Impurity
[catalogue_number] => PA 18 20870
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[weight] => 351.4
[form] => C16H18FN3O3S
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Rosuvastatin Formyl Impurity
stdClass Object
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[pname] => N-(4-(4-Fluorophenyl)-6-isopropyl-5-((1E,3E)-5-oxohexa-1,3-dien-1-yl)pyrimidin-2-yl)-N-methylmethanesulfonamide
[catalogue_number] => PA 18 20880
[category_ids] => ,80,71,78,70,82,88,92,
[chemical_name] =>
[weight] => 417.5
[form] => C21H24FN3O3S
[cas] => 1803023-44-0
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N-(4-(4-Fluorophenyl)-6-isopropyl-5-((1E,3E)-5-oxohexa-1,3-dien-1-yl)pyrimidin-2-yl)-N-methylmethanesulfonamide
stdClass Object
(
[pname] => (E)-N-(4-(4-Fluorophenyl)-6-isopropyl-5-(3-oxobut-1-en-1-yl)pyrimidin-2-yl)-N-methylmethanesulfonamide
[catalogue_number] => PA 18 20890
[category_ids] => ,80,71,78,70,82,88,92,
[chemical_name] =>
[weight] => 391.46
[form] => C19H22FN3O3S
[cas] => 1899869-35-2
[pslug] => 1899869-35-2-e-n-4-4-fluorophenyl-6-isopropyl-5-3-oxobut-1-en-1-yl-pyrimidin-2-yl-n-methylmethanesulfonamide-pa1820890
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(E)-N-(4-(4-Fluorophenyl)-6-isopropyl-5-(3-oxobut-1-en-1-yl)pyrimidin-2-yl)-N-methylmethanesulfonamide
Catalogue No.:PA 18 20890
Molecular Formula : C19H22FN3O3S
Molecular Weight : 391.46
stdClass Object
(
[pname] => N-(5-((3S,5S,E)-3,5-Dihydroxyhex-1-en-1-yl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
[catalogue_number] => PA 18 20900
[category_ids] => ,80,71,78,70,82,88,92,
[chemical_name] =>
[weight] => 437.53
[form] => C21H28FN3O4S
[cas] => NA
[pslug] => n-5-3s-5s-e-3-5-dihydroxyhex-1-en-1-yl-4-4-fluorophenyl-6-isopropylpyrimidin-2-yl-n-methylmethanesulfonamide-pa1820900
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N-(5-((3S,5S,E)-3,5-Dihydroxyhex-1-en-1-yl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
Catalogue No.:PA 18 20900
Molecular Formula : C21H28FN3O4S
Molecular Weight : 437.53
stdClass Object
(
[pname] => S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin-d6 Calcium Salt
[catalogue_number] => PA STI 028260
[category_ids] => ,80,71,75,78,70,82,88,98,
[chemical_name] =>
[weight] => 564.69
[form] => C25H27D6FN3O7S•1/2Ca
[cas] => NA
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S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin-d6 Calcium Salt
Catalogue No.:PA STI 028260
Molecular Formula : C25H27D6FN3O7S•1/2Ca
Molecular Weight : 564.69
stdClass Object
(
[pname] => N-Desmethyl Rosuvastatin Lactone-d6
[catalogue_number] => PA STI 028640
[category_ids] => ,80,69,71,78,70,82,88,98,
[chemical_name] =>
[weight] => 455.53
[form] => C21H18D6FN3O5S
[cas] => NA
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N-Desmethyl Rosuvastatin Lactone-d6
Catalogue No.:PA STI 028640
Molecular Formula : C21H18D6FN3O5S
Molecular Weight : 455.53
stdClass Object
(
[pname] => Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine Oxide-d6
[catalogue_number] => PA STI 035560
[category_ids] => ,80,71,70,88,98,
[chemical_name] =>
[weight] => 543.62
[form] => C28H23D6FN3O3PS
[cas] => 1185122-39-7
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Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine Oxide-d6
Catalogue No.:PA STI 035560
Molecular Formula : C28H23D6FN3O3PS
Molecular Weight : 543.62
stdClass Object
(
[pname] => Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-d3-methylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine Oxide
[catalogue_number] => PA STI 035570
[category_ids] => ,80,71,70,88,98,
[chemical_name] =>
[weight] => 540.60
[form] => C28H26D3FN3O3PS
[cas] => 2733868-91-0
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Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-d3-methylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine Oxide
Catalogue No.:PA STI 035570
Molecular Formula : C28H26D3FN3O3PS
Molecular Weight : 540.60
stdClass Object
(
[pname] => N-[4-(4-Fluorophenyl)-5-methyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide-d3
[catalogue_number] => PA STI 041970
[category_ids] => ,80,71,78,70,82,98,
[chemical_name] =>
[weight] => 340.43
[form] => C16H17D3FN3O2S
[cas] => 1794941-65-3
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N-[4-(4-Fluorophenyl)-5-methyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide-d3
Catalogue No.:PA STI 041970
Molecular Formula : C16H17D3FN3O2S
Molecular Weight : 340.43
stdClass Object
(
[pname] => Rosuvastatin 4,5-Anhydro Acid
[catalogue_number] => PA 18 20795
[category_ids] => ,80,71,75,78,70,82,88,
[chemical_name] =>
[weight] => 463.52
[form] => C22H26FN3O5S
[cas] => 1346606-44-7
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Rosuvastatin 4,5-Anhydro Acid
Catalogue No.:PA 18 20795
Molecular Formula : C22H26FN3O5S
Molecular Weight : 463.52
stdClass Object
(
[pname] => (R,E)-7-(4-(2-Fluorophenyl)-2-(hydrosulfonyl(methyl)amino)-6-isopropylpyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic Acid
[catalogue_number] => PA 18 20805
[category_ids] => ,80,71,75,78,70,82,88,
[chemical_name] =>
[weight] => 465.5
[form] => C21H24FN3O6S
[cas] => NA
[pslug] => r-e-7-4-2-fluorophenyl-2-hydrosulfonyl-methyl-amino-6-isopropylpyrimidin-5-yl-3-hydroxy-5-oxohept-6-enoic-acid-pa1820805
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(R,E)-7-(4-(2-Fluorophenyl)-2-(hydrosulfonyl(methyl)amino)-6-isopropylpyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic Acid
stdClass Object
(
[pname] => 3-Oxo Rosuvastatin
[catalogue_number] => PA 18 0201052
[category_ids] => ,69,71,70,78,70,82,
[chemical_name] =>
[weight] => 479.52
[form] => C22H26FN3O6S
[cas] => 1346747-49-6
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Catalogue No.:PA 18 0201052
Molecular Formula : C22H26FN3O6S
Molecular Weight : 479.52