ruxolitinib

Heterocycles - Ruxolitinib is used to treat myelofibrosis or polycythemia vera, which are bone marrow disorders that that affect your body's ability to produce blood cells. Reference standards of Ruxolitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => rac-Ruxolitinib-13C,15N2
    [catalogue_number] => PA STI 078620
    [category_ids] => ,80,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 309.34
    [form] => C1613CH18N415N2
    [cas] => NA
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PA STI 078620
PA STI 078620

rac-Ruxolitinib-13C,15N2


  • Catalogue No.:PA STI 078620

  • CAS :

    NA

  • Molecular Formula : C1613CH18N415N2

  • Molecular Weight : 309.34

stdClass Object
(
    [pname] => rac-Ruxolitinib-d8
    [catalogue_number] => PA STI 078630
    [category_ids] => ,80,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 314.41
    [form] => C17H10D8N6
    [cas] => NA
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PA STI 078630
PA STI 078630

rac-Ruxolitinib-d8


  • Catalogue No.:PA STI 078630

  • CAS :

    NA

  • Molecular Formula : C17H10D8N6

  • Molecular Weight : 314.41

stdClass Object
(
    [pname] => Ruxolitinib
    [catalogue_number] => PA 18 82000
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 306.37
    [form] => C17H18N6
    [cas] => 941678-49-5
    [pslug] => 941678-49-5-ruxolitinib-api-pa1882000
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PA 18 82000
PA 18 82000

Ruxolitinib


  • Catalogue No.:PA 18 82000

  • CAS :

    941678-49-5

  • Molecular Formula : C17H18N6

  • Molecular Weight : 306.37

stdClass Object
(
    [pname] => Ruxolitinib Acetamide Impurity
    [catalogue_number] => PA 18 0821017
    [category_ids] => ,80,69,71,78,82,117,76,
    [chemical_name] => 
    [weight] => 377.45
    [form] => C20H23N7O
    [cas] => NA
    [pslug] => ruxolitinib-acetamide-impurity-pa180821017
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PA 18 0821017
PA 18 0821017

Ruxolitinib Acetamide Impurity


  • Catalogue No.:PA 18 0821017

  • CAS :

    NA

  • Molecular Formula : C20H23N7O

  • Molecular Weight : 377.45

stdClass Object
(
    [pname] => (+)-Di-p-anisoyl-D-tartaric Acid
    [catalogue_number] => PA 18 0821023
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 418.35
    [form] => C20H18O10
    [cas] => 191605-10-4
    [pslug] => 191605-10-4-di-p-anisoyl-d-tartaric-acid-pa180821023
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PA 18 0821023
PA 18 0821023

(+)-Di-p-anisoyl-D-tartaric Acid


  • Catalogue No.:PA 18 0821023

  • CAS :

    191605-10-4

  • Molecular Formula : C20H18O10

  • Molecular Weight : 418.35

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    [pname] => (R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (2S,3S)-2,3-bis(benzoyloxy)succinate
    [catalogue_number] => PA 18 0821025
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 794.94
    [form] => C41H46N6O9Si
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PA 18 0821025
PA 18 0821025

(R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (2S,3S)-2,3-bis(benzoyloxy)succinate


  • Catalogue No.:PA 18 0821025

  • CAS :

    1236033-04-7

  • Molecular Formula : C41H46N6O9Si

  • Molecular Weight : 794.94

stdClass Object
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    [pname] => 3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821026
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 315.22
    [form] => C17H26BN3O2
    [cas] => 1153949-38-2
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PA 18 0821026
PA 18 0821026

3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821026

  • CAS :

    1153949-38-2

  • Molecular Formula : C17H26BN3O2

  • Molecular Weight : 315.22

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    [catalogue_number] => PA 18 0821028
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    [weight] => 315.22
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PA 18 0821028
PA 18 0821028

(R)-3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821028

  • CAS :

    1146629-84-6

  • Molecular Formula : C17H26BN3O2

  • Molecular Weight : 315.22

stdClass Object
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    [pname] => (R)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate
    [catalogue_number] => PA 18 0821031
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    [weight] => 420.52
    [form] => C23H28N6O2
    [cas] => 1146629-80-2
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PA 18 0821031
PA 18 0821031

(R)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate


  • Catalogue No.:PA 18 0821031

  • CAS :

    1146629-80-2

  • Molecular Formula : C23H28N6O2

  • Molecular Weight : 420.52

stdClass Object
(
    [pname] => 4-Amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylic Acid
    [catalogue_number] => PA 18 0821032
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 326.36
    [form] => C16H18N6O2
    [cas] => NA
    [pslug] => 4-amino-6-1-2-cyano-1-cyclopentylethyl-1h-pyrazol-4-yl-pyrimidine-5-carboxylic-acid-pa180821032
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PA 18 0821032
PA 18 0821032

4-Amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylic Acid


  • Catalogue No.:PA 18 0821032

  • CAS :

    NA

  • Molecular Formula : C16H18N6O2

  • Molecular Weight : 326.36

stdClass Object
(
    [pname] => rac-Ruxolitinib
    [catalogue_number] => PA 18 0821033
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 306.37
    [form] => C17H18N6
    [cas] => 941688-05-7
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PA 18 0821033
PA 18 0821033

rac-Ruxolitinib


  • Catalogue No.:PA 18 0821033

  • CAS :

    941688-05-7

  • Molecular Formula : C17H18N6

  • Molecular Weight : 306.37

stdClass Object
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    [pname] => 3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821034
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 338.37
    [form] => C17H18N6O2
    [cas] => 1289219-34-6
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PA 18 0821034
PA 18 0821034

3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821034

  • CAS :

    1289219-34-6

  • Molecular Formula : C17H18N6O2

  • Molecular Weight : 338.37

stdClass Object
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    [pname] => 3-Cyclopentyl-3-(4-(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821035
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 322.37
    [form] => C17H18N6O
    [cas] => 1289218-88-7
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PA 18 0821035
PA 18 0821035

3-Cyclopentyl-3-(4-(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821035

  • CAS :

    1289218-88-7

  • Molecular Formula : C17H18N6O

  • Molecular Weight : 322.37

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    [pname] => 3-Cyclopentyl-3-(4-(5,6-dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821036
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 340.39
    [form] => C17H20N6O2
    [cas] => 1289219-47-1
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PA 18 0821036
PA 18 0821036

3-Cyclopentyl-3-(4-(5,6-dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821036

  • CAS :

    1289219-47-1

  • Molecular Formula : C17H20N6O2

  • Molecular Weight : 340.39

stdClass Object
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    [pname] => (R)-3-(4-(6-Amino-5-(hydroxymethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
    [catalogue_number] => PA 18 0821037
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    [weight] => 312.38
    [form] => C16H20N6O
    [cas] => NA
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PA 18 0821037
PA 18 0821037

(R)-3-(4-(6-Amino-5-(hydroxymethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile


  • Catalogue No.:PA 18 0821037

  • CAS :

    NA

  • Molecular Formula : C16H20N6O

  • Molecular Weight : 312.38

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    [pname] => (3R)-3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
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    [category_ids] => ,69,71,78,70,82,
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    [weight] => 338.37
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PA 18 0821038
PA 18 0821038

(3R)-3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821038

  • CAS :

    3029006-62-7

  • Molecular Formula : C17H18N6O2

  • Molecular Weight : 338.37

stdClass Object
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    [pname] => (S)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate
    [catalogue_number] => PA 18 0821039
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 420.52
    [form] => C23H28N6O2
    [cas] => 1236033-23-0
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PA 18 0821039
PA 18 0821039

(S)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate


  • Catalogue No.:PA 18 0821039

  • CAS :

    1236033-23-0

  • Molecular Formula : C23H28N6O2

  • Molecular Weight : 420.52

stdClass Object
(
    [pname] => (R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanoic Acid
    [catalogue_number] => PA 18 0821040
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 368.44
    [form] => C19H24N6O2
    [cas] => NA
    [pslug] => r-3-cyclopentyl-3-5-dimethylamino-4-7h-pyrrolo-2-3-d-pyrimidin-4-yl-1h-pyrazol-1-yl-propanoic-acid-pa180821040
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PA 18 0821040
PA 18 0821040

(R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanoic Acid


  • Catalogue No.:PA 18 0821040

  • CAS :

    NA

  • Molecular Formula : C19H24N6O2

  • Molecular Weight : 368.44

stdClass Object
(
    [pname] => (R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanamide
    [catalogue_number] => PA 18 0821041
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 367.46
    [form] => C19H25N7O
    [cas] => NA
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PA 18 0821041
PA 18 0821041

(R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanamide


  • Catalogue No.:PA 18 0821041

  • CAS :

    NA

  • Molecular Formula : C19H25N7O

  • Molecular Weight : 367.46

stdClass Object
(
    [pname] => (R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821042
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 349.44
    [form] => C19H23N7
    [cas] => NA
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PA 18 0821042
PA 18 0821042

(R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821042

  • CAS :

    NA

  • Molecular Formula : C19H23N7

  • Molecular Weight : 349.44

stdClass Object
(
    [pname] => 4-((1-Methylpyrrolidin-2-ylidene)methyl)-7H-pyrrolo[2,3-d]pyrimidine
    [catalogue_number] => PA 18 0821043
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 214.27
    [form] => C12H14N4
    [cas] => NA
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PA 18 0821043
PA 18 0821043

4-((1-Methylpyrrolidin-2-ylidene)methyl)-7H-pyrrolo[2,3-d]pyrimidine


  • Catalogue No.:PA 18 0821043

  • CAS :

    NA

  • Molecular Formula : C12H14N4

  • Molecular Weight : 214.27

stdClass Object
(
    [pname] => (R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 1,3-dioxide
    [catalogue_number] => PA 18 0821044
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 338.37
    [form] => C17H18N6O2
    [cas] => NA
    [pslug] => r-4-1-2-cyano-1-cyclopentylethyl-1h-pyrazol-4-yl-7h-pyrrolo-2-3-d-pyrimidine-1-3-dioxide-pa180821044
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PA 18 0821044
PA 18 0821044

(R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 1,3-dioxide


  • Catalogue No.:PA 18 0821044

  • CAS :

    NA

  • Molecular Formula : C17H18N6O2

  • Molecular Weight : 338.37

stdClass Object
(
    [pname] => (S)-3-Cyclopentyl-3-hydroxypropanenitrile
    [catalogue_number] => PA 18 0821049
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 139.2
    [form] => C8H13NO
    [cas] => 1699727-68-8
    [pslug] => 1699727-68-8-s-3-cyclopentyl-3-hydroxypropanenitrile-pa180821049
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PA 18 0821049
PA 18 0821049

(S)-3-Cyclopentyl-3-hydroxypropanenitrile


  • Catalogue No.:PA 18 0821049

  • CAS :

    1699727-68-8

  • Molecular Formula : C8H13NO

  • Molecular Weight : 139.2

stdClass Object
(
    [pname] => 4,4'-(1H-Pyrazole-1,4-diyl)bis(7H-pyrrolo[2,3-d]pyrimidine)
    [catalogue_number] => PA 18 0821050
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 302.3
    [form] => C15H10N8
    [cas] => NA
    [pslug] => 4-4-1h-pyrazole-1-4-diyl-bis-7h-pyrrolo-2-3-d-pyrimidine-pa180821050
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PA 18 0821050
PA 18 0821050

4,4'-(1H-Pyrazole-1,4-diyl)bis(7H-pyrrolo[2,3-d]pyrimidine)


  • Catalogue No.:PA 18 0821050

  • CAS :

    NA

  • Molecular Formula : C15H10N8

  • Molecular Weight : 302.3

stdClass Object
(
    [pname] => (4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate
    [catalogue_number] => PA 18 0821051
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 420.52
    [form] => C23H28N6O2
    [cas] => 1236033-05-8
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PA 18 0821051
PA 18 0821051

(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate


  • Catalogue No.:PA 18 0821051

  • CAS :

    1236033-05-8

  • Molecular Formula : C23H28N6O2

  • Molecular Weight : 420.52

stdClass Object
(
    [pname] => (1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)boronic Acid
    [catalogue_number] => PA 18 0821054
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 233.08
    [form] => C11H16BN3O2
    [cas] => 1974336-79-2
    [pslug] => 1974336-79-2-1-2-cyano-1-cyclopentylethyl-1h-pyrazol-4-yl-boronic-acid-pa180821054
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PA 18 0821054
PA 18 0821054

(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)boronic Acid


  • Catalogue No.:PA 18 0821054

  • CAS :

    1974336-79-2

  • Molecular Formula : C11H16BN3O2

  • Molecular Weight : 233.08

stdClass Object
(
    [pname] => 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
    [catalogue_number] => PA 18 0821055
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 194.04
    [form] => C9H15BN2O2
    [cas] => 269410-08-4
    [pslug] => 269410-08-4-4-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-1h-pyrazole-pa180821055
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PA 18 0821055
PA 18 0821055

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole


  • Catalogue No.:PA 18 0821055

  • CAS :

    269410-08-4

  • Molecular Formula : C9H15BN2O2

  • Molecular Weight : 194.04

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