ruxolitinib

Ruxolitinib is used to treat myelofibrosis or polycythemia vera, which are bone marrow disorders that that affect your body's ability to produce blood cells. Reference standards of Ruxolitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => rac-Ruxolitinib-13C,15N2
    [catalogue_number] => PA STI 078620
    [category_ids] => ,80,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 309.34
    [form] => C1613CH18N415N2
    [cas] => NA
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PA STI 078620

rac-Ruxolitinib-13C,15N2


  • Catalogue No.:PA STI 078620

  • CAS :

    NA

  • Molecular Formula : C1613CH18N415N2

  • Molecular Weight : 309.34

stdClass Object
(
    [pname] => rac-Ruxolitinib-d8
    [catalogue_number] => PA STI 078630
    [category_ids] => ,80,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 314.41
    [form] => C17H10D8N6
    [cas] => NA
    [pslug] => rac-ruxolitinib-d8-pasti078630
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PA STI 078630

rac-Ruxolitinib-d8


  • Catalogue No.:PA STI 078630

  • CAS :

    NA

  • Molecular Formula : C17H10D8N6

  • Molecular Weight : 314.41

stdClass Object
(
    [pname] => Ruxolitinib
    [catalogue_number] => PA 18 82000
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 306.37
    [form] => C17H18N6
    [cas] => 941678-49-5
    [pslug] => 941678-49-5-ruxolitinib-api-pa1882000
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PA 18 82000

Ruxolitinib


  • Catalogue No.:PA 18 82000

  • CAS :

    941678-49-5

  • Molecular Formula : C17H18N6

  • Molecular Weight : 306.37

stdClass Object
(
    [pname] => Ruxolitinib Acetamide Impurity
    [catalogue_number] => PA 18 0821017
    [category_ids] => ,80,69,71,78,82,117,76,
    [chemical_name] => 
    [weight] => 377.45
    [form] => C20H23N7O
    [cas] => NA
    [pslug] => ruxolitinib-acetamide-impurity-pa180821017
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PA 18 0821017

Ruxolitinib Acetamide Impurity


  • Catalogue No.:PA 18 0821017

  • CAS :

    NA

  • Molecular Formula : C20H23N7O

  • Molecular Weight : 377.45

stdClass Object
(
    [pname] => (+)-Di-p-anisoyl-D-tartaric Acid
    [catalogue_number] => PA 18 0821023
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 418.35
    [form] => C20H18O10
    [cas] => 191605-10-4
    [pslug] => 191605-10-4-di-p-anisoyl-d-tartaric-acid-pa180821023
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PA 18 0821023

(+)-Di-p-anisoyl-D-tartaric Acid


  • Catalogue No.:PA 18 0821023

  • CAS :

    191605-10-4

  • Molecular Formula : C20H18O10

  • Molecular Weight : 418.35

stdClass Object
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    [pname] => (R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (2S,3S)-2,3-bis(benzoyloxy)succinate
    [catalogue_number] => PA 18 0821025
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 794.94
    [form] => C41H46N6O9Si
    [cas] => 1236033-04-7
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PA 18 0821025

(R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (2S,3S)-2,3-bis(benzoyloxy)succinate


  • Catalogue No.:PA 18 0821025

  • CAS :

    1236033-04-7

  • Molecular Formula : C41H46N6O9Si

  • Molecular Weight : 794.94

stdClass Object
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    [pname] => 3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821026
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 315.22
    [form] => C17H26BN3O2
    [cas] => 1153949-38-2
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PA 18 0821026

3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821026

  • CAS :

    1153949-38-2

  • Molecular Formula : C17H26BN3O2

  • Molecular Weight : 315.22

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    [pname] => (R)-3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821028
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    [weight] => 315.22
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    [cas] => 1146629-84-6
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PA 18 0821028

(R)-3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821028

  • CAS :

    1146629-84-6

  • Molecular Formula : C17H26BN3O2

  • Molecular Weight : 315.22

stdClass Object
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    [pname] => (R)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate
    [catalogue_number] => PA 18 0821031
    [category_ids] => ,80,69,71,78,70,82,
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    [weight] => 420.52
    [form] => C23H28N6O2
    [cas] => 1146629-80-2
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PA 18 0821031

(R)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate


  • Catalogue No.:PA 18 0821031

  • CAS :

    1146629-80-2

  • Molecular Formula : C23H28N6O2

  • Molecular Weight : 420.52

stdClass Object
(
    [pname] => 4-Amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylic Acid
    [catalogue_number] => PA 18 0821032
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 326.36
    [form] => C16H18N6O2
    [cas] => NA
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PA 18 0821032

4-Amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylic Acid


  • Catalogue No.:PA 18 0821032

  • CAS :

    NA

  • Molecular Formula : C16H18N6O2

  • Molecular Weight : 326.36

stdClass Object
(
    [pname] => rac-Ruxolitinib
    [catalogue_number] => PA 18 0821033
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 306.37
    [form] => C17H18N6
    [cas] => 941688-05-7
    [pslug] => 941688-05-7-rac-ruxolitinib-pa180821033
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PA 18 0821033

rac-Ruxolitinib


  • Catalogue No.:PA 18 0821033

  • CAS :

    941688-05-7

  • Molecular Formula : C17H18N6

  • Molecular Weight : 306.37

stdClass Object
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    [pname] => 3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821034
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 338.37
    [form] => C17H18N6O2
    [cas] => 1289219-34-6
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PA 18 0821034

3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821034

  • CAS :

    1289219-34-6

  • Molecular Formula : C17H18N6O2

  • Molecular Weight : 338.37

stdClass Object
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    [pname] => 3-Cyclopentyl-3-(4-(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821035
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 322.37
    [form] => C17H18N6O
    [cas] => 1289218-88-7
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PA 18 0821035

3-Cyclopentyl-3-(4-(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821035

  • CAS :

    1289218-88-7

  • Molecular Formula : C17H18N6O

  • Molecular Weight : 322.37

stdClass Object
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    [pname] => 3-Cyclopentyl-3-(4-(5,6-dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821036
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 340.39
    [form] => C17H20N6O2
    [cas] => 1289219-47-1
    [pslug] => 1289219-47-1-3-cyclopentyl-3-4-5-6-dihydroxy-6-7-dihydro-5h-pyrrolo-2-3-d-pyrimidin-4-yl-1h-pyrazol-1-yl-propanenitrile-pa180821036
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PA 18 0821036

3-Cyclopentyl-3-(4-(5,6-dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821036

  • CAS :

    1289219-47-1

  • Molecular Formula : C17H20N6O2

  • Molecular Weight : 340.39

stdClass Object
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    [pname] => (R)-3-(4-(6-Amino-5-(hydroxymethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
    [catalogue_number] => PA 18 0821037
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 312.38
    [form] => C16H20N6O
    [cas] => NA
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PA 18 0821037

(R)-3-(4-(6-Amino-5-(hydroxymethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile


  • Catalogue No.:PA 18 0821037

  • CAS :

    NA

  • Molecular Formula : C16H20N6O

  • Molecular Weight : 312.38

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    [pname] => (3R)-3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821038
    [category_ids] => ,69,71,78,70,82,
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    [weight] => 338.37
    [form] => C17H18N6O2
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PA 18 0821038

(3R)-3-Cyclopentyl-3-(4-(6-hydroxy-5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821038

  • CAS :

    3029006-62-7

  • Molecular Formula : C17H18N6O2

  • Molecular Weight : 338.37

stdClass Object
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    [pname] => (S)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate
    [catalogue_number] => PA 18 0821039
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 420.52
    [form] => C23H28N6O2
    [cas] => 1236033-23-0
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PA 18 0821039

(S)-(4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate


  • Catalogue No.:PA 18 0821039

  • CAS :

    1236033-23-0

  • Molecular Formula : C23H28N6O2

  • Molecular Weight : 420.52

stdClass Object
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    [pname] => (R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanoic Acid
    [catalogue_number] => PA 18 0821040
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 368.44
    [form] => C19H24N6O2
    [cas] => NA
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PA 18 0821040

(R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanoic Acid


  • Catalogue No.:PA 18 0821040

  • CAS :

    NA

  • Molecular Formula : C19H24N6O2

  • Molecular Weight : 368.44

stdClass Object
(
    [pname] => (R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanamide
    [catalogue_number] => PA 18 0821041
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 367.46
    [form] => C19H25N7O
    [cas] => NA
    [pslug] => r-3-cyclopentyl-3-5-dimethylamino-4-7h-pyrrolo-2-3-d-pyrimidin-4-yl-1h-pyrazol-1-yl-propanamide-pa180821041
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PA 18 0821041

(R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanamide


  • Catalogue No.:PA 18 0821041

  • CAS :

    NA

  • Molecular Formula : C19H25N7O

  • Molecular Weight : 367.46

stdClass Object
(
    [pname] => (R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821042
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 349.44
    [form] => C19H23N7
    [cas] => NA
    [pslug] => r-3-cyclopentyl-3-5-dimethylamino-4-7h-pyrrolo-2-3-d-pyrimidin-4-yl-1h-pyrazol-1-yl-propanenitrile-pa180821042
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PA 18 0821042

(R)-3-Cyclopentyl-3-(5-(dimethylamino)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821042

  • CAS :

    NA

  • Molecular Formula : C19H23N7

  • Molecular Weight : 349.44

stdClass Object
(
    [pname] => 4-((1-Methylpyrrolidin-2-ylidene)methyl)-7H-pyrrolo[2,3-d]pyrimidine
    [catalogue_number] => PA 18 0821043
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 214.27
    [form] => C12H14N4
    [cas] => NA
    [pslug] => 4-1-methylpyrrolidin-2-ylidene-methyl-7h-pyrrolo-2-3-d-pyrimidine-pa180821043
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PA 18 0821043

4-((1-Methylpyrrolidin-2-ylidene)methyl)-7H-pyrrolo[2,3-d]pyrimidine


  • Catalogue No.:PA 18 0821043

  • CAS :

    NA

  • Molecular Formula : C12H14N4

  • Molecular Weight : 214.27

CPHI INDIA- 28, 30 November