Solifenacin-impurities | Pharmaffiliates

solifenacin

A muscarinic receptor antagonist drug used for treating contraction of overactive bladder such as incontinence, urinary frequency, and urgency. Solifenacin is a competitive cholinergic receptor antagonist, selective for the M3 receptor subtype. It was manufactured and marketed by Astellas, GlaxoSmithKline and Teva Pharmaceutical Industries. Reference standards of Solifenacin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
    [catalogue_number] => PA 19 50510
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 209.29
    [form] => C15H15N
    [cas] => 180272-45-1
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PA 19 50510

(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline


  • Catalogue No.:PA 19 50510

  • CAS :

    180272-45-1

  • Molecular Formula : C15H15N

  • Molecular Weight : 209.29

stdClass Object
(
    [pname] => Solifenacin (R,R)-Isomer Succinate Salt
    [catalogue_number] => PA 19 50520
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 480.55
    [form] => C27H32N2O6
    [cas] => 862207-70-3
    [pslug] => 862207-70-3-solifenacin-r-r-isomer-succinate-salt-pa1950520
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PA 19 50520

Solifenacin (R,R)-Isomer Succinate Salt


  • Catalogue No.:PA 19 50520

  • CAS :

    862207-70-3

  • Molecular Formula : C27H32N2O6

  • Molecular Weight : 480.55

stdClass Object
(
    [pname] => Solifenacin (R,S)-Isomer Hydrochloride Salt
    [catalogue_number] => PA 19 50530
    [category_ids] => 82,80,79,78,71,70,69
    [chemical_name] => 
    [weight] => 398.93
    [form] => C23H27ClN2O2
    [cas] => 180468-40-0
    [pslug] => 180468-40-0-solifenacin-r-s-isomer-hydrochloride-salt-pa1950530
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PA 19 50530

Solifenacin (R,S)-Isomer Hydrochloride Salt


  • Catalogue No.:PA 19 50530

  • CAS :

    180468-40-0

  • Molecular Formula : C23H27ClN2O2

  • Molecular Weight : 398.93

stdClass Object
(
    [pname] => Solifenacin (S,S)-Isomer Hydrochloride Salt
    [catalogue_number] => PA 19 50540
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 398.93
    [form] => C23H27ClN2O2
    [cas] => 180468-38-6
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PA 19 50540

Solifenacin (S,S)-Isomer Hydrochloride Salt


  • Catalogue No.:PA 19 50540

  • CAS :

    180468-38-6

  • Molecular Formula : C23H27ClN2O2

  • Molecular Weight : 398.93

stdClass Object
(
    [pname] => (R)-(-)-3-Quinuclidinol
    [catalogue_number] => PA 19 50550
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 127.18
    [form] => C7H13NO
    [cas] => 25333-42-0
    [pslug] => 25333-42-0-r-3-quinuclidinol-pa1950550
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PA 19 50550

(R)-(-)-3-Quinuclidinol


  • Catalogue No.:PA 19 50550

  • CAS :

    25333-42-0

  • Molecular Formula : C7H13NO

  • Molecular Weight : 127.18

stdClass Object
(
    [pname] => Ethyl (S)-1-Phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate
    [catalogue_number] => PA 19 50560
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 281.35
    [form] => C18H19NO2
    [cas] => 180468-42-2
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PA 19 50560

Ethyl (S)-1-Phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate


  • Catalogue No.:PA 19 50560

  • CAS :

    180468-42-2

  • Molecular Formula : C18H19NO2

  • Molecular Weight : 281.35

stdClass Object
(
    [pname] => 1-Phenyl-3,4-dihydroisoquinoline
    [catalogue_number] => PA 19 50580
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 207.27
    [form] => C15H13N
    [cas] => 52250-50-7
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PA 19 50580

1-Phenyl-3,4-dihydroisoquinoline


  • Catalogue No.:PA 19 50580

  • CAS :

    52250-50-7

  • Molecular Formula : C15H13N

  • Molecular Weight : 207.27

stdClass Object
(
    [pname] => N,N-Dimethyl-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxamide
    [catalogue_number] => PA 19 50600
    [category_ids] => ,79,80,71,
    [chemical_name] => 
    [weight] => 280.36
    [form] => C18H20N2O
    [cas] => 1956369-89-3
    [pslug] => 1956369-89-3-n-n-dimethyl-1-phenyl-3-4-dihydroisoquinoline-2-1h-carboxamide-pa1950600
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PA 19 50600

N,N-Dimethyl-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxamide


  • Catalogue No.:PA 19 50600

  • CAS :

    1956369-89-3

  • Molecular Formula : C18H20N2O

  • Molecular Weight : 280.36

stdClass Object
(
    [pname] => (S)-(1S,2R,3R,4S)-2-Ethylquinuclidin-3-yl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 50620
    [category_ids] => ,79,80,71,75,78,
    [chemical_name] => 
    [weight] => 390.52
    [form] => C25H30N2O2
    [cas] => 605696-10-4
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PA 19 50620

(S)-(1S,2R,3R,4S)-2-Ethylquinuclidin-3-yl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 50620

  • CAS :

    605696-10-4

  • Molecular Formula : C25H30N2O2

  • Molecular Weight : 390.52

stdClass Object
(
    [pname] => (S)-(1S,2R,3R,4S)-2-Methylquinuclidin-3-yl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 50630
    [category_ids] => ,79,80,71,75,78,
    [chemical_name] => 
    [weight] => 376.49
    [form] => C24H28N2O2
    [cas] => NA
    [pslug] => s-1s-2r-3r-4s-2-methylquinuclidin-3-yl-1-phenyl-3-4-dihydroisoquinoline-2-1h-carboxylate-pa1950630
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PA 19 50630

(S)-(1S,2R,3R,4S)-2-Methylquinuclidin-3-yl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 50630

  • CAS :

    NA

  • Molecular Formula : C24H28N2O2

  • Molecular Weight : 376.49

stdClass Object
(
    [pname] => (S)-(+)-3-Quinuclidinol
    [catalogue_number] => PA 19 50640
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 127.18
    [form] => C7H13NO
    [cas] => 34583-34-1
    [pslug] => 34583-34-1-s-3-quinuclidinol-pa1950640
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PA 19 50640

(S)-(+)-3-Quinuclidinol


  • Catalogue No.:PA 19 50640

  • CAS :

    34583-34-1

  • Molecular Formula : C7H13NO

  • Molecular Weight : 127.18

stdClass Object
(
    [pname] => (S)-1-Phenyl-3,4-dihydroisoquinoline-2(1H)-Carboxylic Acid
    [catalogue_number] => PA 19 50650
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 253.3
    [form] => C16H15NO2
    [cas] => 1035272-88-8
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PA 19 50650

(S)-1-Phenyl-3,4-dihydroisoquinoline-2(1H)-Carboxylic Acid


  • Catalogue No.:PA 19 50650

  • CAS :

    1035272-88-8

  • Molecular Formula : C16H15NO2

  • Molecular Weight : 253.3

stdClass Object
(
    [pname] => (R)-Quinuclidin-3-yl 2-benzoylphenethylcarbamate
    [catalogue_number] => PA 19 50660
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 378.46
    [form] => C23H26N2O3
    [cas] => NA
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PA 19 50660

(R)-Quinuclidin-3-yl 2-benzoylphenethylcarbamate


  • Catalogue No.:PA 19 50660

  • CAS :

    NA

  • Molecular Formula : C23H26N2O3

  • Molecular Weight : 378.46

stdClass Object
(
    [pname] => (R)-Quinuclidin-3-yl-[2-(2-Benzoyl phenyl)ethyl]carbamate Succinate
    [catalogue_number] => PA 19 50670
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 496.55
    [form] => C27H32N2O7
    [cas] => NA
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PA 19 50670

(R)-Quinuclidin-3-yl-[2-(2-Benzoyl phenyl)ethyl]carbamate Succinate


  • Catalogue No.:PA 19 50670

  • CAS :

    NA

  • Molecular Formula : C27H32N2O7

  • Molecular Weight : 496.55

stdClass Object
(
    [pname] => (S)-Phenyl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 50680
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 329.39
    [form] => C22H19NO2
    [cas] => 1203447-95-3
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PA 19 50680

(S)-Phenyl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 50680

  • CAS :

    1203447-95-3

  • Molecular Formula : C22H19NO2

  • Molecular Weight : 329.39

stdClass Object
(
    [pname] => Solifenacin Succinate Impurity S1
    [catalogue_number] => PA 19 50690
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 379.47
    [form] => C23H27N2O3+
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PA 19 50690

Solifenacin Succinate Impurity S1


  • Catalogue No.:PA 19 50690

  • CAS :

    NA

  • Molecular Formula : C23H27N2O3+

  • Molecular Weight : 379.47

stdClass Object
(
    [pname] => (1R,3R,4R)-3-((4-Hydroxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)oxy)quinuclidine 1-oxide
    [catalogue_number] => PA 19 50700
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 394.46
    [form] => C23H26N2O4
    [cas] => NA
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PA 19 50700

(1R,3R,4R)-3-((4-Hydroxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)oxy)quinuclidine 1-oxide


  • Catalogue No.:PA 19 50700

  • CAS :

    NA

  • Molecular Formula : C23H26N2O4

  • Molecular Weight : 394.46

stdClass Object
(
    [pname] => Solifenacin cis-Hydroxy Impurity
    [catalogue_number] => PA 19 50710
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 378.46
    [form] => C23H26N2O3
    [cas] => 201660-36-8
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PA 19 50710

Solifenacin cis-Hydroxy Impurity


  • Catalogue No.:PA 19 50710

  • CAS :

    201660-36-8

  • Molecular Formula : C23H26N2O3

  • Molecular Weight : 378.46

stdClass Object
(
    [pname] => 1,2-Dihydro-1-phenylisoquinoline
    [catalogue_number] => PA 19 50720
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 207.27
    [form] => C15H13N
    [cas] => 134021-15-1
    [pslug] => 134021-15-1-1-2-dihydro-1-phenylisoquinoline-pa1950720
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PA 19 50720

1,2-Dihydro-1-phenylisoquinoline


  • Catalogue No.:PA 19 50720

  • CAS :

    134021-15-1

  • Molecular Formula : C15H13N

  • Molecular Weight : 207.27

stdClass Object
(
    [pname] => Trans-4-Hydroxy Solifenacin (Mixture of Diastereomers)
    [catalogue_number] => PA 19 50730
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 378.46
    [form] => C23H26N2O3
    [cas] => NA
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PA 19 50730

Trans-4-Hydroxy Solifenacin (Mixture of Diastereomers)


  • Catalogue No.:PA 19 50730

  • CAS :

    NA

  • Molecular Formula : C23H26N2O3

  • Molecular Weight : 378.46

stdClass Object
(
    [pname] => (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline-d5
    [catalogue_number] => PA STI 073290
    [category_ids] => ,80,69,71,98,
    [chemical_name] => 
    [weight] => 214.32
    [form] => C15H10D5N
    [cas] => 1217607-42-5
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PA STI 073290

(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline-d5


  • Catalogue No.:PA STI 073290

  • CAS :

    1217607-42-5

  • Molecular Formula : C15H10D5N

  • Molecular Weight : 214.32

stdClass Object
(
    [pname] => Solifenacin-d5 Hydrochloride
    [catalogue_number] => PA STI 079630
    [category_ids] => ,79,80,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 403.96
    [form] => C23H22D5ClN2O2
    [cas] => 1426174-05-1
    [pslug] => 1426174-05-1-solifenacin-d5-hydrochloride-pasti079630
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PA STI 079630

Solifenacin-d5 Hydrochloride


  • Catalogue No.:PA STI 079630

  • CAS :

    1426174-05-1

  • Molecular Formula : C23H22D5ClN2O2

  • Molecular Weight : 403.96

stdClass Object
(
    [pname] => (1S,3S-)Solifenacin Hydrochloride-d5
    [catalogue_number] => PA STI 079640
    [category_ids] => ,79,80,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 403.96
    [form] => C23H22D5ClN2O2
    [cas] => NA
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PA STI 079640

(1S,3S-)Solifenacin Hydrochloride-d5


  • Catalogue No.:PA STI 079640

  • CAS :

    NA

  • Molecular Formula : C23H22D5ClN2O2

  • Molecular Weight : 403.96

stdClass Object
(
    [pname] => (1R,3S-)Solifenacin-d5 Hydrochloride
    [catalogue_number] => PA STI 079650
    [category_ids] => ,79,80,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 403.96
    [form] => C23H22D5ClN2O2
    [cas] => 1217810-85-9
    [pslug] => 1217810-85-9-1r-3s-solifenacin-d5-hydrochloride-pasti079650
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PA STI 079650

(1R,3S-)Solifenacin-d5 Hydrochloride


  • Catalogue No.:PA STI 079650

  • CAS :

    1217810-85-9

  • Molecular Formula : C23H22D5ClN2O2

  • Molecular Weight : 403.96

stdClass Object
(
    [pname] => 1-Phenyl-1,2,3,4-tetrahydroisoquinoline
    [catalogue_number] => PA 19 50780
    [category_ids] => ,80,71,93,78,70,82,
    [chemical_name] => 
    [weight] => 209.29
    [form] => C15H15N
    [cas] => 22990-19-8
    [pslug] => 22990-19-8-1-phenyl-1-2-3-4-tetrahydroisoquinoline-pa1950780
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PA 19 50780

1-Phenyl-1,2,3,4-tetrahydroisoquinoline


  • Catalogue No.:PA 19 50780

  • CAS :

    22990-19-8

  • Molecular Formula : C15H15N

  • Molecular Weight : 209.29

stdClass Object
(
    [pname] => 3,4-Dihydro-1-phenylisoquinoline Hydrochloride
    [catalogue_number] => PA 19 50790
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 243.73
    [form] => C15H14ClN
    [cas] => 52250-51-8
    [pslug] => 52250-51-8-3-4-dihydro-1-phenylisoquinoline-hydrochloride-pa1950790
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PA 19 50790

3,4-Dihydro-1-phenylisoquinoline Hydrochloride


  • Catalogue No.:PA 19 50790

  • CAS :

    52250-51-8

  • Molecular Formula : C15H14ClN

  • Molecular Weight : 243.73

stdClass Object
(
    [pname] => Solifenacin Identification Mixture A
    [catalogue_number] => PA 19 0501004
    [category_ids] => ,80,71,76,75,93,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
    [pslug] => solifenacin-identification-mixture-a-pa190501004
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PA 19 0501004

Solifenacin Identification Mixture A


  • Catalogue No.:PA 19 0501004

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => Solifenacin Identification Mixture B
    [catalogue_number] => PA 19 0501003
    [category_ids] => ,80,71,76,75,93,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
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PA 19 0501003

Solifenacin Identification Mixture B


  • Catalogue No.:PA 19 0501003

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => (S)-Quinuclidinyl Benzoyl Solifenacin
    [catalogue_number] => PA 19 2091002
    [category_ids] => ,80,79,75,71,
    [chemical_name] => 
    [weight] => 378.47
    [form] => C23H26N2O3
    [cas] => 2407763-28-2
    [pslug] => 2407763-28-2-s-quinuclidinyl-benzoyl-solifenacin-pa192091002
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PA 19 2091002

(S)-Quinuclidinyl Benzoyl Solifenacin


  • Catalogue No.:PA 19 2091002

  • CAS :

    2407763-28-2

  • Molecular Formula : C23H26N2O3

  • Molecular Weight : 378.47