tacrolimus
Heterocycles
- A macrolide lactone, Tacrolimus is an immunosupressant drug. Tacrolimus is a macrolide calcineurin inhibitor used mainly after allogeneic organ transplant to lower the risk of organ rejection. Topical ointment is used to treat severe cases of atopic dermatitis (eczema)Reference standards of Tacrolimus API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Tacrolimus Open Ring
[catalogue_number] => PA 20 01520
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[weight] => 822.05
[form] => C44H71NO13
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Catalogue No.:PA 20 01520
Molecular Formula : C44H71NO13
Molecular Weight : 822.05
stdClass Object
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[pname] => 19-Epi Ascomycin
[catalogue_number] => PA 20 01530
[category_ids] => ,69,71,70,78,82,
[chemical_name] =>
[weight] => 792.01
[form] => C43H69NO12
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Catalogue No.:PA 20 01530
Molecular Formula : C43H69NO12
Molecular Weight : 792.01
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[pname] => 15,19:20,23-Diepoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,21(4H,8H,23H)-trione, 5,6,11,12,13,14,15,16,17,18,19,20,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)
[catalogue_number] => PA 20 01660
[category_ids] => ,69,78,70,82,71,
[chemical_name] =>
[weight] => 804.02
[form] => C44H69NO12
[cas] => 144432-22-4
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15,19:20,23-Diepoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,21(4H,8H,23H)-trione, 5,6,11,12,13,14,15,16,17,18,19,20,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)
Catalogue No.:PA 20 01660
Molecular Formula : C44H69NO12
Molecular Weight : 804.02
stdClass Object
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[pname] => Tacrolimus Regioisomer
[catalogue_number] => PA 20 01670
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[form] => C44H69NO12
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Catalogue No.:PA 20 01670
Molecular Formula : C44H69NO12
Molecular Weight : 804.02
stdClass Object
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[pname] => 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506-13C, D2 (Major)
[catalogue_number] => PA STI 013110
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[chemical_name] =>
[weight] => 1035.54
[form] => C5513CH95D2NO12Si2
[cas] => 1356352-20-9
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24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506-13C, D2 (Major)
Catalogue No.:PA STI 013110
Molecular Formula : C5513CH95D2NO12Si2
Molecular Weight : 1035.54
stdClass Object
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[pname] => (3S,4R,5S,8R,12S,14S,15R,16S,18R,26aS,Z)-8-Allyl-5,15-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-3H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentaone
[catalogue_number] => PA 20 01750
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[weight] => 804.03
[form] => C44H69NO12
[cas] => NA
[pslug] => 3s-4r-5s-8r-12s-14s-15r-16s-18r-26as-z-8-allyl-5-15-dihydroxy-3-e-1-1r-3r-4r-4-hydroxy-3-methoxycyclohexyl-prop-1-en-2-yl-14-16-dimethoxy-4-10-12-18-tetramethyl-5-6-11-12-13-14-15-16-17-18-24-25-26-26a-tetradecahydro-3h-pyrido-2-1-c-1-oxa-4-azacyclotricosine-1-7-19-20-21-4h-8h-23h-pentaone-pa2001750
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(3S,4R,5S,8R,12S,14S,15R,16S,18R,26aS,Z)-8-Allyl-5,15-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-3H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentaone
Catalogue No.:PA 20 01750
Molecular Formula : C44H69NO12
Molecular Weight : 804.03
stdClass Object
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[pname] => 24,33-bis-O-(tert-Butyldimethylsilyl) Tacrolimus
[catalogue_number] => PA 20 01760
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[chemical_name] =>
[weight] => 1032.56
[form] => C56H97NO12Si2
[cas] => 133941-75-0
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24,33-bis-O-(tert-Butyldimethylsilyl) Tacrolimus
Catalogue No.:PA 20 01760
Molecular Formula : C56H97NO12Si2
Molecular Weight : 1032.56
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[pname] => 24,33-bis-O-(tert-Butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (Mixture of Diastereomers)
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[chemical_name] =>
[weight] => 1066.57
[form] => C56H99NO14Si2
[cas] => 1356932-17-6
[pslug] => 1356932-17-6-24-33-bis-o-tert-butyldimethylsilyl-37-38-dehydro-37-38-dihydroxy-fk-506-mixture-of-diastereomers-pa2001770
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24,33-bis-O-(tert-Butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (Mixture of Diastereomers)
Catalogue No.:PA 20 01770
Molecular Formula : C56H99NO14Si2
Molecular Weight : 1066.57
stdClass Object
(
[pname] => 33-tert-Butyldimethylsilyloxy-FK 506
[catalogue_number] => PA 20 01780
[category_ids] => ,69,71,78,70,82,
[chemical_name] =>
[weight] => 918.29
[form] => C50H83NO12Si
[cas] => 104987-25-9
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33-tert-Butyldimethylsilyloxy-FK 506
Catalogue No.:PA 20 01780
Molecular Formula : C50H83NO12Si
Molecular Weight : 918.29
stdClass Object
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[pname] => Tacrolimus System Suitability Mixture
[catalogue_number] => PA 20 0671000
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Tacrolimus System Suitability Mixture
