tolvaptan
Tolvaptan is used to treat hyponatremia associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone. It is an aquaretic drug.Reference standards of Tolvaptan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Tolvaptan
[catalogue_number] => PA 20 98000
[category_ids] => ,80,71,78,70,82,
[chemical_name] =>
[weight] => 448.94
[form] => C26H25ClN2O3
[cas] => 150683-30-0
[pslug] => 150683-30-0-tolvaptan-api-pa2098000
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Catalogue No.:PA 20 98000
Molecular Formula : C26H25ClN2O3
Molecular Weight : 448.94
stdClass Object
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[pname] => 2-Methyl-4-(2-methylbenzoylamino)-benzoic Acid
[catalogue_number] => PA 20 98510
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[weight] => 269.3
[form] => C16H15NO3
[cas] => 317374-08-6
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2-Methyl-4-(2-methylbenzoylamino)-benzoic Acid
stdClass Object
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[pname] => N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide
[catalogue_number] => PA 20 98520
[category_ids] => 82,80,78,71,70
[chemical_name] =>
[weight] => 414.5
[form] => C26H26N2O3
[cas] => 1432725-23-9
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N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide
stdClass Object
(
[pname] => (4-Amino-2-methylphenyl)(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone
[catalogue_number] => PA 20 98530
[category_ids] => 82,80,78,71,70
[chemical_name] =>
[weight] => 330.81
[form] => C18H19ClN2O2
[cas] => 1432725-24-0
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(4-Amino-2-methylphenyl)(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone
Catalogue No.:PA 20 98530
Molecular Formula : C18H19ClN2O2
Molecular Weight : 330.81
stdClass Object
(
[pname] => 5-Dehydro Tolvaptan
[catalogue_number] => PA 20 98540
[category_ids] => 70,71,80,82,78
[chemical_name] =>
[weight] => 446.93
[form] => C26H23ClN2O3
[cas] => 137973-76-3
[pslug] => 137973-76-3-5-dehydro-tolvaptan-pa2098540
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Catalogue No.:PA 20 98540
Molecular Formula : C26H23ClN2O3
Molecular Weight : 446.93
stdClass Object
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[catalogue_number] => PA 20 98550
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[chemical_name] =>
[weight] => 358.78
[form] => C18H15ClN2O4
[cas] => 137982-91-3
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7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
Catalogue No.:PA 20 98550
Molecular Formula : C18H15ClN2O4
Molecular Weight : 358.78
stdClass Object
(
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[weight] => 328.79
[form] => C18H17ClN2O2
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1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one
Catalogue No.:PA 20 98560
Molecular Formula : C18H17ClN2O2
Molecular Weight : 328.79
stdClass Object
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[pname] => N-(4-(7-Chloro-4-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide
[catalogue_number] => PA 20 98570
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[weight] => 460.95
[form] => C27H25ClN2O3
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N-(4-(7-Chloro-4-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide
Catalogue No.:PA 20 98570
Molecular Formula : C27H25ClN2O3
Molecular Weight : 460.95
stdClass Object
(
[pname] => Tolvaptan-d7
[catalogue_number] => PA STI 083840
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[chemical_name] =>
[weight] => 455.98
[form] => C26H18D7ClN2O3
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Catalogue No.:PA STI 083840
Molecular Formula : C26H18D7ClN2O3
Molecular Weight : 455.98
stdClass Object
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[pname] => 2-Methyl-4-nitrobenzoic Acid
[catalogue_number] => PA 20 0981028
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[weight] => 181.15
[form] => C8H7NO4
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2-Methyl-4-nitrobenzoic Acid
Catalogue No.:PA 20 0981028
Molecular Formula : C8H7NO4
Molecular Weight : 181.15
stdClass Object
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[pname] => 1-(4-Amino-2-methylbenzoyl)-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl 4-amino-2-methylbenzoate
[catalogue_number] => PA 20 0981038
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[weight] => 461.95
[form] => C26H24ClN3O3
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1-(4-Amino-2-methylbenzoyl)-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl 4-amino-2-methylbenzoate
Catalogue No.:PA 20 0981038
Molecular Formula : C26H24ClN3O3
Molecular Weight : 461.95
stdClass Object
(
[pname] => 7-Chloro-1-nitroso-2,3-dihydro-1H-benzo[b]azepine
[catalogue_number] => PA 20 0981039
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[weight] => 208.65
[form] => C10H9ClN2O
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7-Chloro-1-nitroso-2,3-dihydro-1H-benzo[b]azepine
Catalogue No.:PA 20 0981039
Molecular Formula : C10H9ClN2O
Molecular Weight : 208.65
stdClass Object
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[pname] => tert-Butyl (3aS,10bR)-9-chloro-6-nitroso-3,3a,4,5,6,10b-hexahydrobenzo[b]pyrrolo[2,3-d]azepine-1(2H)-carboxylate
[catalogue_number] => PA 20 0981040
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[weight] => 351.83
[form] => C17H22ClN3O3
[cas] => NA
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tert-Butyl (3aS,10bR)-9-chloro-6-nitroso-3,3a,4,5,6,10b-hexahydrobenzo[b]pyrrolo[2,3-d]azepine-1(2H)-carboxylate
Catalogue No.:PA 20 0981040
Molecular Formula : C17H22ClN3O3
Molecular Weight : 351.83
stdClass Object
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[pname] => N-(4-(7-Chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-4-methylbenzamide
[catalogue_number] => PA 20 0981041
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[weight] => 446.93
[form] => C26H23ClN2O3
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N-(4-(7-Chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-4-methylbenzamide
Catalogue No.:PA 20 0981041
Molecular Formula : C26H23ClN2O3
Molecular Weight : 446.93
stdClass Object
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[catalogue_number] => PA 20 0981042
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[weight] => 432.9
[form] => C25H21ClN2O3
[cas] => 1580889-32-2
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N-(4-(7-Chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)benzamide
stdClass Object
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[pname] => 1-(4-Amino-2-methylbenzoyl)-7-bromo-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
[catalogue_number] => PA 20 0981043
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[chemical_name] =>
[weight] => 373.25
[form] => C18H17BrN2O2
[cas] => NA
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1-(4-Amino-2-methylbenzoyl)-7-bromo-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.:PA 20 0981043
Molecular Formula : C18H17BrN2O2
Molecular Weight : 373.25
stdClass Object
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[catalogue_number] => PA 20 0981044
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[weight] => 324.34
[form] => C18H16N2O4
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1-(2-Methyl-4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.:PA 20 0981044
Molecular Formula : C18H16N2O4
Molecular Weight : 324.34
stdClass Object
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[pname] => 1-(4-Amino-2-methylbenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
[catalogue_number] => PA 20 0981045
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[weight] => 294.35
[form] => C18H18N2O2
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1-(4-Amino-2-methylbenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.:PA 20 0981045
Molecular Formula : C18H18N2O2
Molecular Weight : 294.35
stdClass Object
(
[pname] => 2-Methyl-N-(3-methyl-4-(5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)benzamide
[catalogue_number] => PA 20 0981046
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[weight] => 412.49
[form] => C26H24N2O3
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2-Methyl-N-(3-methyl-4-(5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)benzamide
Catalogue No.:PA 20 0981046
Molecular Formula : C26H24N2O3
Molecular Weight : 412.49
stdClass Object
(
[pname] => 1-(4-Nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
[catalogue_number] => PA 20 0981047
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[chemical_name] =>
[weight] => 310.31
[form] => C17H14N2O4
[cas] => 137975-89-4
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1-(4-Nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.:PA 20 0981047
Molecular Formula : C17H14N2O4
Molecular Weight : 310.31
stdClass Object
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[catalogue_number] => PA 20 0981048
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[weight] => 280.33
[form] => C17H16N2O2
[cas] => 137976-09-1
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1-(4-Aminobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.:PA 20 0981048
Molecular Formula : C17H16N2O2
Molecular Weight : 280.33
stdClass Object
(
[pname] => 2-Methyl-N-(4-(5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)benzamide
[catalogue_number] => PA 20 0981049
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[weight] => 398.46
[form] => C25H22N2O3
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2-Methyl-N-(4-(5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)benzamide
Catalogue No.:PA 20 0981049
Molecular Formula : C25H22N2O3
Molecular Weight : 398.46
stdClass Object
(
[pname] => 7-Chloro-1-nitroso-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
[catalogue_number] => PA 20 0981050
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[chemical_name] =>
[weight] => 224.64
[form] => C10H9ClN2O2
[cas] => NA
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7-Chloro-1-nitroso-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.:PA 20 0981050
Molecular Formula : C10H9ClN2O2
Molecular Weight : 224.64
stdClass Object
(
[pname] => 4-Amino-2-methylbenzoic Acid
[catalogue_number] => PA 20 0981051
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[chemical_name] =>
[weight] => 151.17
[form] => C8H9NO2
[cas] => 2486-75-1
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4-Amino-2-methylbenzoic Acid
Catalogue No.:PA 20 0981051
Molecular Formula : C8H9NO2
Molecular Weight : 151.17
stdClass Object
(
[pname] => 7-Chloro-1-(2-methylbenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
[catalogue_number] => PA 20 0981052
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[chemical_name] =>
[weight] => 313.78
[form] => C18H16ClNO2
[cas] => 1580889-21-9
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7-Chloro-1-(2-methylbenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.:PA 20 0981052
Molecular Formula : C18H16ClNO2
Molecular Weight : 313.78
stdClass Object
(
[pname] => (7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)(o-tolyl)methanone
[catalogue_number] => PA 20 0981053
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[weight] => 315.8
[form] => C18H18ClNO2
[cas] => 1580889-22-0
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(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)(o-tolyl)methanone
stdClass Object
(
[pname] => (4-Amino-2-methylphenyl)(7-chloro-4-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone
[catalogue_number] => PA 20 0981054
[category_ids] => ,80,71,78,70,82,
[chemical_name] =>
[weight] => 344.84
[form] => C19H21ClN2O2
[cas] => 1859916-63-4
[pslug] => 1859916-63-4-4-amino-2-methylphenyl-7-chloro-4-methoxy-2-3-4-5-tetrahydro-1h-benzo-b-azepin-1-yl-methanone-pa200981054
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(4-Amino-2-methylphenyl)(7-chloro-4-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone
Catalogue No.:PA 20 0981054
Molecular Formula : C19H21ClN2O2
Molecular Weight : 344.84
stdClass Object
(
[pname] => (S)-N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide
[catalogue_number] => PA 20 0981055
[category_ids] => ,80,71,78,70,82,
[chemical_name] =>
[weight] => 414.51
[form] => C26H26N2O3
[cas] => NA
[pslug] => s-n-4-5-hydroxy-2-3-4-5-tetrahydro-1h-benzo-b-azepine-1-carbonyl-3-methylphenyl-2-methylbenzamide-pa200981055
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(S)-N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide
Catalogue No.:PA 20 0981055
Molecular Formula : C26H26N2O3
Molecular Weight : 414.51
stdClass Object
(
[pname] => (S)-N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)benzamide
[catalogue_number] => PA 20 0981056
[category_ids] => ,80,71,78,70,82,
[chemical_name] =>
[weight] => 434.92
[form] => C25H23ClN2O3
[cas] => NA
[pslug] => s-n-4-7-chloro-5-hydroxy-2-3-4-5-tetrahydro-1h-benzo-b-azepine-1-carbonyl-3-methylphenyl-benzamide-pa200981056
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(S)-N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)benzamide
Catalogue No.:PA 20 0981056
Molecular Formula : C25H23ClN2O3
Molecular Weight : 434.92
stdClass Object
(
[pname] => N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-2-methylphenyl)-2-methylbenzamide
[catalogue_number] => PA 20 0981057
[category_ids] => ,80,71,78,70,82,
[chemical_name] =>
[weight] => 448.95
[form] => C26H25ClN2O3
[cas] => NA
[pslug] => n-4-7-chloro-5-hydroxy-2-3-4-5-tetrahydro-1h-benzo-b-azepine-1-carbonyl-2-methylphenyl-2-methylbenzamide-pa200981057
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N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-2-methylphenyl)-2-methylbenzamide
Catalogue No.:PA 20 0981057
Molecular Formula : C26H25ClN2O3
Molecular Weight : 448.95
