Ambrisentan-Impurities | Pharmaffiliates

ambrisentan

Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. Reference standards of Ambrisentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ambrisentan Vinyloxy Impurity
    [catalogue_number] => PA 28 46550
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 302.37
    [form] => C20H18N2O
    [cas] => 1639429-81-4
    [pslug] => 1639429-81-4-ambrisentan-vinyloxy-impurity-pa2846550
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PA 28 46550

Ambrisentan Vinyloxy Impurity


  • Catalogue No.:PA 28 46550

  • CAS :

    1639429-81-4

  • Molecular Formula : C20H18N2O

  • Molecular Weight : 302.37

stdClass Object
(
    [pname] => (R)-Ambrisentan
    [catalogue_number] => PA 28 46560
    [category_ids] => ,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 378.16
    [form] => C22H22N2O4
    [cas] => 1007358-76-0
    [pslug] => 1007358-76-0-r-ambrisentan-pa2846560
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PA 28 46560

(R)-Ambrisentan


  • Catalogue No.:PA 28 46560

  • CAS :

    1007358-76-0

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.16

stdClass Object
(
    [pname] => rac 4-Hydroxymethyl Ambrisentan-d3
    [catalogue_number] => PA STI 050030
    [category_ids] => ,80,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 397.44
    [form] => C22H19D3N2O5
    [cas] =>  1287096-42-7
    [pslug] => 1287096-42-7-rac-4-hydroxymethyl-ambrisentan-d3-pasti050030
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PA STI 050030

rac 4-Hydroxymethyl Ambrisentan-d3


  • Catalogue No.:PA STI 050030

  • CAS :

    1287096-42-7

  • Molecular Formula : C22H19D3N2O5

  • Molecular Weight : 397.44

stdClass Object
(
    [pname] => Ambrisentan Acyl β-D-Glucuronide
    [catalogue_number] => PA 28 46610
    [category_ids] => ,80,95,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 554.55
    [form] => C28H30N20O10
    [cas] => 1106685-58-8
    [pslug] => 1106685-58-8-ambrisentan-acyl-beta-d-glucuronide-pa2846610
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PA 28 46610

Ambrisentan Acyl β-D-Glucuronide


  • Catalogue No.:PA 28 46610

  • CAS :

    1106685-58-8

  • Molecular Formula : C28H30N20O10

  • Molecular Weight : 554.55

stdClass Object
(
    [pname] => 2,3-Dihydroxy-3,3-diphenylpropionic Acid Methyl Ester
    [catalogue_number] => PA 28 0461000
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 272.3
    [form] => C16H16O4
    [cas] => NA
    [pslug] => -2-3-dihydroxy-3-3-diphenylpropionic-acid-methyl-ester-pa280461000
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PA 28 0461000

2,3-Dihydroxy-3,3-diphenylpropionic Acid Methyl Ester


  • Catalogue No.:PA 28 0461000

  • CAS :

    NA

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.3

stdClass Object
(
    [pname] => (S)-4-Hydroxymethyl Ambrisentan
    [catalogue_number] => PA 28 0461001
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 394.43
    [form] => C22H22N2O5
    [cas] => 1106685-66-8
    [pslug] => 1106685-66-8-s-4-hydroxymethyl-ambrisentan-pa280461001
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PA 28 0461001

(S)-4-Hydroxymethyl Ambrisentan


  • Catalogue No.:PA 28 0461001

  • CAS :

    1106685-66-8

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

stdClass Object
(
    [pname] => (R,S)-Ambrisentan acyl-β-D-glucuronide
    [catalogue_number] => PA 28 0461002
    [category_ids] => ,70,75,76,78,82,95,
    [chemical_name] => 
    [weight] => 554.55
    [form] => C28H30N2O10
    [cas] => 1106685-82-8
    [pslug] => 1106685-82-8-r-s-ambrisentan-acyl-beta-d-glucuronide-pa280461002
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PA 28 0461002

(R,S)-Ambrisentan acyl-β-D-glucuronide


  • Catalogue No.:PA 28 0461002

  • CAS :

    1106685-82-8

  • Molecular Formula : C28H30N2O10

  • Molecular Weight : 554.55

stdClass Object
(
    [pname] => Ambrisentan Hydroxy Acid Impurity (R-Isomer)
    [catalogue_number] => PA 28 0461003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 272.3
    [form] => C16H16O4
    [cas] => 178306-49-5
    [pslug] => 178306-49-5-ambrisentan-hydroxy-acid-impurity-r-isomer-pa280461003
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PA 28 0461003

Ambrisentan Hydroxy Acid Impurity (R-Isomer)


  • Catalogue No.:PA 28 0461003

  • CAS :

    178306-49-5

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.3

stdClass Object
(
    [pname] => rac 4-Hydroxymethyl Ambrisentan
    [catalogue_number] => PA 28 0461004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 394.43
    [form] => C22H22N2O5
    [cas] => 1106685-84-0
    [pslug] => 1106685-84-0-rac-4-hydroxymethyl-ambrisentan-pa280461004
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PA 28 0461004

rac 4-Hydroxymethyl Ambrisentan


  • Catalogue No.:PA 28 0461004

  • CAS :

    1106685-84-0

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

stdClass Object
(
    [pname] => Ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate
    [catalogue_number] => PA 28 0461005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 406.48
    [form] => C24H26N2O4
    [cas] => 1349854-31-4
    [pslug] => 1349854-31-4-ethyl-s-2-4-6-dimethylpyrimidin-2-yl-oxy-3-methoxy-3-3-diphenylpropanoate-pa280461005
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PA 28 0461005

Ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate


  • Catalogue No.:PA 28 0461005

  • CAS :

    1349854-31-4

  • Molecular Formula : C24H26N2O4

  • Molecular Weight : 406.48

stdClass Object
(
    [pname] => 2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ethyl ester
    [catalogue_number] => PA 28 0461006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 406.48
    [form] => C24H26N2O4
    [cas] => NA
    [pslug] => 2-4-6-dimethylpyrimidin-2-yl-oxy-3-methoxy-3-3-diphenyl-propanoic-acid-ethyl-ester-pa280461006
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PA 28 0461006

2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ethyl ester


  • Catalogue No.:PA 28 0461006

  • CAS :

    NA

  • Molecular Formula : C24H26N2O4

  • Molecular Weight : 406.48

stdClass Object
(
    [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid
    [catalogue_number] => PA 28 0461007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 346.39
    [form] => C21H18N2O3
    [cas] => 1312092-82-2
    [pslug] => 1312092-82-2-2-4-6-dimethylpyrimidin-2-yl-oxy-3-3-diphenylacrylic-acid-pa280461007
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PA 28 0461007

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid


  • Catalogue No.:PA 28 0461007

  • CAS :

    1312092-82-2

  • Molecular Formula : C21H18N2O3

  • Molecular Weight : 346.39

stdClass Object
(
    [pname] => Ambrisentan N-Oxide
    [catalogue_number] => PA 28 0461008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 394.43
    [form] => C22H22N2O5
    [cas] => NA
    [pslug] => ambrisentan-n-oxide-pa280461008
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PA 28 0461008

Ambrisentan N-Oxide


  • Catalogue No.:PA 28 0461008

  • CAS :

    NA

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

stdClass Object
(
    [pname] => (S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
    [catalogue_number] => PA STI 088903
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 397.45
    [form] => C22H19D3N2O5
    [cas] => NA
    [pslug] => s-2-4-hydroxymethyl-6-methyl-d3-pyrimidin-2-yl-oxy-3-methoxy-3-3-diphenylpropanoic-acid-pasti088903
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PA STI 088903

(S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid


  • Catalogue No.:PA STI 088903

  • CAS :

    NA

  • Molecular Formula : C22H19D3N2O5

  • Molecular Weight : 397.45

stdClass Object
(
    [pname] => Ambrisentan D3
    [catalogue_number] => PA STI 088904
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 381.45
    [form] => C22H19D3N2O4
    [cas] => 1046116-26-0
    [pslug] => 1046116-26-0-ambrisentan-d3-pasti088904
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PA STI 088904

Ambrisentan D3


  • Catalogue No.:PA STI 088904

  • CAS :

    1046116-26-0

  • Molecular Formula : C22H19D3N2O4

  • Molecular Weight : 381.45

stdClass Object
(
    [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1-phenylethan-1-one
    [catalogue_number] => PAI 01 016041
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 242.28
    [form] => C14H14N2O2
    [cas] => 2052996-29-7
    [pslug] => 2052996-29-7-2-4-6-dimethylpyrimidin-2-yl-oxy-1-phenylethan-1-one-pai01016041
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PAI 01 016041

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1-phenylethan-1-one


  • Catalogue No.:PAI 01 016041

  • CAS :

    2052996-29-7

  • Molecular Formula : C14H14N2O2

  • Molecular Weight : 242.28

stdClass Object
(
    [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1,1-diphenylethan-1-ol
    [catalogue_number] => PAI 01 016042
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 320.39
    [form] => C20H20N2O2
    [cas] => 2052996-28-6
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PAI 01 016042

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1,1-diphenylethan-1-ol


  • Catalogue No.:PAI 01 016042

  • CAS :

    2052996-28-6

  • Molecular Formula : C20H20N2O2

  • Molecular Weight : 320.39

stdClass Object
(
    [pname] => Diphenylacetaldehyde
    [catalogue_number] => PA 28 0461009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 196.25
    [form] => C14H12O
    [cas] => 947-91-1
    [pslug] => 947-91-1-diphenylacetaldehyde-pa280461009
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PA 28 0461009

Diphenylacetaldehyde


  • Catalogue No.:PA 28 0461009

  • CAS :

    947-91-1

  • Molecular Formula : C14H12O

  • Molecular Weight : 196.25

stdClass Object
(
    [pname] => 4-Hydroxymethyl Ambrisentan D5
    [catalogue_number] => PA STI 089231
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 399.46
    [form] => C22H17D5N2O5
    [cas] => 2012598-50-2
    [pslug] => 2012598-50-2-4-hydroxymethyl-ambrisentan-d5-pasti089231
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PA STI 089231

4-Hydroxymethyl Ambrisentan D5


  • Catalogue No.:PA STI 089231

  • CAS :

    2012598-50-2

  • Molecular Formula : C22H17D5N2O5

  • Molecular Weight : 399.46