bendamustine hydrochloride
Impurities
- An alkylating agent with chemical formula 1Hbenzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1 methyl-, monohydrochloride. It contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent. It is used for the treatment of chronic lymphocytic leukemia and lymphomas. Reference standards of Bendamustine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Bendamustine Hydrochloride
[catalogue_number] => PA 02 07000
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 394.72
[form] => C16H22Cl3N3O2
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Bendamustine Hydrochloride
Catalogue No.:PA 02 07000
Molecular Formula : C16H22Cl3N3O2
Molecular Weight : 394.72
stdClass Object
(
[pname] => Bendamustine Methyl Ester
[catalogue_number] => PA 02 07510
[category_ids] => ,75,78,70,82,
[chemical_name] =>
[weight] => 372.29
[form] => C17H23Cl2N3O2
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Bendamustine Methyl Ester
Catalogue No.:PA 02 07510
Molecular Formula : C17H23Cl2N3O2
Molecular Weight : 372.29
stdClass Object
(
[pname] => Bendamustine Ethyl Ester
[catalogue_number] => PA 02 07520
[category_ids] => ,82,79,78,75,71,70,
[chemical_name] =>
[weight] => 386.32
[form] => C18H25Cl2N3O2
[cas] => 87475-54-5
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Catalogue No.:PA 02 07520
Molecular Formula : C18H25Cl2N3O2
Molecular Weight : 386.32
stdClass Object
(
[pname] => Bendamustine Isopropyl Ester
[catalogue_number] => PA 02 07530
[category_ids] => ,79,71,75,78,70,82,
[chemical_name] =>
[weight] => 400.34
[form] => C19H27Cl2N3O2
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Bendamustine Isopropyl Ester
Catalogue No.:PA 02 07530
Molecular Formula : C19H27Cl2N3O2
Molecular Weight : 400.34
stdClass Object
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[pname] => Dihydroxy Bendamustine
[catalogue_number] => PA 02 07540
[category_ids] => ,70,71,75,78,79,82,
[chemical_name] =>
[weight] => 321.37
[form] => C16H23N3O4
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Catalogue No.:PA 02 07540
Molecular Formula : C16H23N3O4
Molecular Weight : 321.37
stdClass Object
(
[pname] => Deschloroethyl Bendamustine Hydrochloride
[catalogue_number] => PA 02 07550
[category_ids] => ,71,75,79,
[chemical_name] =>
[weight] => 332.23
[form] => C14H19Cl2N3O2
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Deschloroethyl Bendamustine Hydrochloride
Catalogue No.:PA 02 07550
Molecular Formula : C14H19Cl2N3O2
Molecular Weight : 332.23
stdClass Object
(
[pname] => Bendamustine Dideschloroethyl Acid
[catalogue_number] => PA 02 07560
[category_ids] => ,75,84,
[chemical_name] =>
[weight] => 233.27
[form] => C12H15N3O2
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Bendamustine Dideschloroethyl Acid
Catalogue No.:PA 02 07560
Molecular Formula : C12H15N3O2
Molecular Weight : 233.27
stdClass Object
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[pname] => Bendamustine Dideschloroethyl Ethyl Ester
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[weight] => 261.32
[form] => C14H19N3O2
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Bendamustine Dideschloroethyl Ethyl Ester
Catalogue No.:PA 02 07570
Molecular Formula : C14H19N3O2
Molecular Weight : 261.32
stdClass Object
(
[pname] => 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
[catalogue_number] => PA 02 07600
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[weight] => 381.9
[form] => C19H28ClN3O3
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5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
stdClass Object
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[pname] => 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
[catalogue_number] => PA 02 07610
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[chemical_name] =>
[weight] => 353.87
[form] => C16H20ClN3O2S
[cas] => 191939-34-1
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4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
Catalogue No.:PA 02 07610
Molecular Formula : C16H20ClN3O2S
Molecular Weight : 353.87
stdClass Object
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[weight] => 305.33
[form] => C15H19N3O4
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Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate
Catalogue No.:PA 02 07620
Molecular Formula : C15H19N3O4
Molecular Weight : 305.33
stdClass Object
(
[pname] => 1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane
[catalogue_number] => PA 02 07630
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[weight] => 394.38
[form] => C19H18N6O4
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1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane
Catalogue No.:PA 02 07630
Molecular Formula : C19H18N6O4
Molecular Weight : 394.38
stdClass Object
(
[pname] => N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide
[catalogue_number] => PA 02 07640
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[chemical_name] =>
[weight] => 430.41
[form] => C19H22N6O6
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N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide
Catalogue No.:PA 02 07640
Molecular Formula : C19H22N6O6
Molecular Weight : 430.41
stdClass Object
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[pname] => 2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)
[catalogue_number] => PA 02 07650
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[chemical_name] =>
[weight] => 334.42
[form] => C19H22N6
[cas] => 847588-86-7
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2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)
Catalogue No.:PA 02 07650
Molecular Formula : C19H22N6
Molecular Weight : 334.42
stdClass Object
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[catalogue_number] => PA 02 07660
[category_ids] => ,80,71,76,75,
[chemical_name] =>
[weight] => 432.34
[form] => C19H27Cl2N3O4
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2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
Catalogue No.:PA 02 07660
Molecular Formula : C19H27Cl2N3O4
Molecular Weight : 432.34
stdClass Object
(
[pname] => 4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
[catalogue_number] => PA 02 07670
[category_ids] => ,80,71,76,75,
[chemical_name] =>
[weight] => 381.85
[form] => C18H24ClN3O4
[cas] => NA
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4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
Catalogue No.:PA 02 07670
Molecular Formula : C18H24ClN3O4
Molecular Weight : 381.85
stdClass Object
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[pname] => Bendamustine Chloro Dimer Impurity
[catalogue_number] => PA 02 07710
[category_ids] => ,70,71,75,78,79,82,
[chemical_name] =>
[weight] => 680.06
[form] => C32H41Cl3N6O4
[cas] => 1228551-91-4
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Bendamustine Chloro Dimer Impurity
Catalogue No.:PA 02 07710
Molecular Formula : C32H41Cl3N6O4
Molecular Weight : 680.06
stdClass Object
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[pname] => 4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
[catalogue_number] => PA 02 07720
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[chemical_name] =>
[weight] => 291.35
[form] => C15H21N3O3
[cas] => NA
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4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
Catalogue No.:PA 02 07720
Molecular Formula : C15H21N3O3
Molecular Weight : 291.35
stdClass Object
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[catalogue_number] => PA 02 07730
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[weight] => 319.4
[form] => C17H25N3O3
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Isopropyl 4-(5-((2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
stdClass Object
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[pname] => Bendamustine Deschloro Dimer Impurity
[catalogue_number] => PA 02 07740
[category_ids] => ,79,71,75,78,70,82,
[chemical_name] =>
[weight] => 624.73
[form] => C32H44N6O7
[cas] => 1391052-61-1
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Bendamustine Deschloro Dimer Impurity
Catalogue No.:PA 02 07740
Molecular Formula : C32H44N6O7
Molecular Weight : 624.73
stdClass Object
(
[pname] => Bendamustine Dimer 2'-Allyl Ester
[catalogue_number] => PA 02 07750
[category_ids] => ,79,71,75,78,70,82,
[chemical_name] =>
[weight] => 720.13
[form] => C35H45Cl3N6O4
[cas] => NA
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Bendamustine Dimer 2'-Allyl Ester
Catalogue No.:PA 02 07750
Molecular Formula : C35H45Cl3N6O4
Molecular Weight : 720.13
stdClass Object
(
[pname] => Bendamustine Monohydroxy Acid Hydrochloride
[catalogue_number] => PA 02 0071000
[category_ids] => ,75,76,78,82,
[chemical_name] =>
[weight] => 376.28
[form] => C16H23Cl2N3O3
[cas] => 109882-26-0
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Bendamustine Monohydroxy Acid Hydrochloride
Catalogue No.:PA 02 0071000
Molecular Formula : C16H23Cl2N3O3
Molecular Weight : 376.28
stdClass Object
(
[pname] => 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid
[catalogue_number] => PA 02 0071001
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 263.25
[form] => C12H13N3O4
[cas] => 31349-48-1
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4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid
Catalogue No.:PA 02 0071001
Molecular Formula : C12H13N3O4
Molecular Weight : 263.25
stdClass Object
(
[pname] => N-Methyl-2,4-dinitroaniline
[catalogue_number] => PA 02 0071002
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 197.15
[form] => C7H7N3O4
[cas] => 2044-88-4
[pslug] => 2044-88-4-n-methyl-2-4-dinitroaniline-pa020071002
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N-Methyl-2,4-dinitroaniline
Catalogue No.:PA 02 0071002
Molecular Formula : C7H7N3O4
Molecular Weight : 197.15
stdClass Object
(
[pname] => Bendamustine Ether Impurity
[catalogue_number] => PA 02 0071003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 303.36
[form] => C16H21N3O3
[cas] => 1228552-02-0
[pslug] => 1228552-02-0-bendamustine-ether-impurity-pa020071003
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Bendamustine Ether Impurity
Catalogue No.:PA 02 0071003
Molecular Formula : C16H21N3O3
Molecular Weight : 303.36
stdClass Object
(
[pname] => Bendamustine Dideschloroethyl Acid Hydrochloride
[catalogue_number] => PA 02 0071004
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 269.73
[form] => C12H16ClN3O2
[cas] => 1179363-38-2
[pslug] => 1179363-38-2-bendamustine-dideschloroethyl-acid-hydrochloride-pa020071004
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Bendamustine Dideschloroethyl Acid Hydrochloride
Catalogue No.:PA 02 0071004
Molecular Formula : C12H16ClN3O2
Molecular Weight : 269.73
