clarithromycin
Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration. It is a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process.. Reference standards of Clarithromycin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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Clarithromycin - Impurity A
Catalogue No.:PA 03 60010
Molecular Formula : C38H69NO14
Molecular Weight : 763.95
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Clarithromycin - Impurity B
Catalogue No.:PA 03 60020
Molecular Formula : C37H67NO13
Molecular Weight : 733.93
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Clarithromycin - Impurity C
Catalogue No.:PA 03 60030
Molecular Formula : C38H70N2O13
Molecular Weight : 762.97
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Clarithromycin - Impurity D
Catalogue No.:PA 03 60040
Molecular Formula : C37H67NO13
Molecular Weight : 733.93
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Clarithromycin - Impurity E
Catalogue No.:PA 03 60050
Molecular Formula : C39H71NO13
Molecular Weight : 761.98
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Clarithromycin - Impurity F
Catalogue No.:PA 03 60060
Molecular Formula : C39H71NO13
Molecular Weight : 761.98
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Clarithromycin - Impurity G
Catalogue No.:PA 03 60070
Molecular Formula : C39H72N2O13
Molecular Weight : 776.99
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Clarithromycin - Impurity H
Catalogue No.:PA 03 60080
Molecular Formula : C38H67NO14
Molecular Weight : 761.94
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Catalogue No.:PA 03 60090
Molecular Formula : C30H55NO10
Molecular Weight : 589.76
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Catalogue No.:PA 03 60100
Molecular Formula : C37H68N2O13
Molecular Weight : 748.94
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Catalogue No.:PA 03 60110
Molecular Formula : C30H51NO8
Molecular Weight : 553.73
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Clarithromycin - Impurity L
Catalogue No.:PA 03 60120
Molecular Formula : C38H70N2O13
Molecular Weight : 762.97
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Clarithromycin - Impurity M
Catalogue No.:PA 03 60130
Molecular Formula : C37H68N2O13
Molecular Weight : 748.94
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Clarithromycin - Impurity N
Catalogue No.:PA 03 60140
Molecular Formula : C38H67NO12
Molecular Weight : 729.94
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Clarithromycin - Impurity O
Catalogue No.:PA 03 60150
Molecular Formula : C39H72N2O13
Molecular Weight : 776.99
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Clarithromycin - Impurity P
Catalogue No.:PA 03 60160
Molecular Formula : C39H71NO13
Molecular Weight : 761.98
stdClass Object
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[pname] => 9-Ketal Oxime Clarithromycin
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9-Ketal Oxime Clarithromycin
Catalogue No.:PA 03 60530
Molecular Formula : C42H78N2O14
Molecular Weight : 835.07
stdClass Object
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Catalogue No.:PA 03 60540
Molecular Formula : C41H76N2O14
Molecular Weight : 821.05
stdClass Object
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Catalogue No.:PA 03 60560
Molecular Formula : C38H69NO14
Molecular Weight : 763.95
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14-Hydroxy Clarithromycin
Catalogue No.:PA 03 0601000
Molecular Formula : C38H69NO14
Molecular Weight : 763.96
stdClass Object
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[catalogue_number] => PA 03 0601002
[category_ids] => ,75,76,78,70,82,
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[weight] => 432.55
[form] => C22H40O8
[cas] => 2376120-29-3
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(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-Ethyl-4,6,12,13-tetrahydroxy-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PA 03 0601002
Molecular Formula : C22H40O8
Molecular Weight : 432.55
stdClass Object
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8a-Aza-8a-homoerythromycin A
Catalogue No.:PA 03 0601003
Molecular Formula : C37H68N2O13
Molecular Weight : 748.95
stdClass Object
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[pname] => (2S,3R,4S,6R)-2-(((2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-15-oxo-7-propyl-1-oxa-7-azacyclopentadecan-11-yl)oxy)-3-hydroxy-N,N,6-trimethyltetrahydro-2H-pyran-4-amine oxide
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[cas] => NA
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(2S,3R,4S,6R)-2-(((2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-15-oxo-7-propyl-1-oxa-7-azacyclopentadecan-11-yl)oxy)-3-hydroxy-N,N,6-trimethyltetrahydro-2H-pyran-4-amine oxide
Catalogue No.:PA 03 0601004
Molecular Formula : C40H76N2O13
Molecular Weight : 793.05
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[catalogue_number] => PA 03 0601005
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[weight] => 734.97
[form] => C37H70N2O12
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N-Despropyl gamithromycin
Catalogue No.:PA 03 0601005
Molecular Formula : C37H70N2O12
Molecular Weight : 734.97
stdClass Object
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[weight] => 777.05
[form] => C40H76N2O12
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(2R,3S,6R,8R,9R,10S,11S,12R)-2-((3R)-2,3-Dihydroxypentan-2-yl)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-hydroxy-11-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,6,8,10,12-pentamethyl-5-propyl-1-oxa-5-azacyclotridecan-13-one
Catalogue No.:PA 03 0601006
Molecular Formula : C40H76N2O12
Molecular Weight : 777.05
stdClass Object
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[pname] => (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10,13-tetrahydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one;
[catalogue_number] => PA 03 0601007
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[weight] => 618.85
[form] => C32H62N2O9
[cas] => 1797448-01-1
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(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10,13-tetrahydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one;
Catalogue No.:PA 03 0601007
Molecular Formula : C32H62N2O9
Molecular Weight : 618.85
stdClass Object
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[weight] => 777.05
[form] => C40H76N2O12
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(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-6-propyl-1-oxa-6-azacyclopentadecan-15-one
Catalogue No.:PA 03 0601008
Molecular Formula : C40H76N2O12
Molecular Weight : 777.05
stdClass Object
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[pname] => (14R)-14-Hydroxy Clarithromycin
[catalogue_number] => PA 03 0601009
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[weight] => 763.96
[form] => C38H69NO14
[cas] => 116836-41-0
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(14R)-14-Hydroxy Clarithromycin
Catalogue No.:PA 03 0601009
Molecular Formula : C38H69NO14
Molecular Weight : 763.96
stdClass Object
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[pname] => N-Nitroso-N-Desmethyl-Clarithromycin
[catalogue_number] => PA 03 0601010
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[weight] => 762.94
[form] => C37H66N2O14
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N-Nitroso-N-Desmethyl-Clarithromycin
Catalogue No.:PA 03 0601010
Molecular Formula : C37H66N2O14
Molecular Weight : 762.94
stdClass Object
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[catalogue_number] => PAI 03 034051
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[weight] => 892.33
[form] => C44H85NO13Si2
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(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PAI 03 034051
Molecular Formula : C44H85NO13Si2
Molecular Weight : 892.33
stdClass Object
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[weight] => 906.36
[form] => C45H87NO13Si2
[cas] => NA
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(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-7,12-dimethoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PAI 03 034052
Molecular Formula : C45H87NO13Si2
Molecular Weight : 906.36
stdClass Object
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[catalogue_number] => PAI 03 034056
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[weight] => 1818.46
[form] => C88H170BN2NaO26Si4
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Boron Complex of 2',4"-O-Bis(trimethylsilyl)-9(S)-9-dihydroClarithromycin
Catalogue No.:PAI 03 034056
Molecular Formula : C88H170BN2NaO26Si4
Molecular Weight : 1818.46
stdClass Object
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[weight] => 906.36
[form] => C45H87NO13Si2
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(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12-hydroxy-7,13-dimethoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PAI 03 034055
Molecular Formula : C45H87NO13Si2
Molecular Weight : 906.36
stdClass Object
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[catalogue_number] => PAI 03 034054
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[weight] => 908.37
[form] => C45H89NO13Si2
[cas] => NA
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(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-10,12-dihydroxy-7,13-dimethoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PAI 03 034054
Molecular Formula : C45H89NO13Si2
Molecular Weight : 908.37
stdClass Object
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[catalogue_number] => PAI 03 034059
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[weight] => 777.01
[form] => C39H72N2O13
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6,4"-Di-O-methylerythromycin A 9-oxime
Catalogue No.:PAI 03 034059
Molecular Formula : C39H72N2O13
Molecular Weight : 777.01
stdClass Object
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[pname] => 2'-O-TMS-6,4"-Di-O-methylerythromycin A 9-[(1-ethoxy-1-methylethyl)-oxime]
[catalogue_number] => PAI 03 034058
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[weight] => 935.32
[form] => C47H90N2O14Si
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2'-O-TMS-6,4"-Di-O-methylerythromycin A 9-[(1-ethoxy-1-methylethyl)-oxime]
Catalogue No.:PAI 03 034058
Molecular Formula : C47H90N2O14Si
Molecular Weight : 935.32
stdClass Object
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[weight] => 921.3
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6-O-Methyl-2'-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime] Erythromycin