Edaravone-impurities | Pharmaffiliates

edaravone

Edaravone is used to help people recover from stroke in Japan, and is used to treat ALS in the US and Japan. It is sold as under the brand names Radicava. Reference standards of Edaravone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Bispyrazolone
    [catalogue_number] => PA 32 06530
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 346.38
    [form] => C20H18N4O2
    [cas] => 7477-67-0
    [pslug] => 7477-67-0-bispyrazolone-pa3206530
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PA 32 06530

Bispyrazolone


  • Catalogue No.:PA 32 06530

  • CAS :

    7477-67-0

  • Molecular Formula : C20H18N4O2

  • Molecular Weight : 346.38

stdClass Object
(
    [pname] => 3,3'-Dimethyl-1,1'-diphenyl[4,4'-bi-1H-pyrazole]-5,5'-diol
    [catalogue_number] => PA 32 06540
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 346.38
    [form] => C20H18N4O2
    [cas] => 177415-76-8
    [pslug] => 177415-76-8-3-3-dimethyl-1-1-diphenyl-4-4-bi-1h-pyrazole-5-5-diol-pa3206540
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PA 32 06540

3,3'-Dimethyl-1,1'-diphenyl[4,4'-bi-1H-pyrazole]-5,5'-diol


  • Catalogue No.:PA 32 06540

  • CAS :

    177415-76-8

  • Molecular Formula : C20H18N4O2

  • Molecular Weight : 346.38

stdClass Object
(
    [pname] => 1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one
    [catalogue_number] => PA 32 06550
    [category_ids] => ,80,71,75,70,82,
    [chemical_name] => 
    [weight] => 174.2
    [form] => C10H10N2O
    [cas] => 19735-89-8
    [pslug] => 19735-89-8-1-2-dihydro-5-methyl-2-phenyl-3h-pyrazol-3-one-pa3206550
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PA 32 06550

1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one


  • Catalogue No.:PA 32 06550

  • CAS :

    19735-89-8

  • Molecular Formula : C10H10N2O

  • Molecular Weight : 174.2

stdClass Object
(
    [pname] => 3-Methyl-1-phenyl-4,5-dihydro-1H-pyrazole-4,5-diol
    [catalogue_number] => PA 32 06560
    [category_ids] => ,80,71,75,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C10H12N2O2
    [cas] => NA
    [pslug] => 3-methyl-1-phenyl-4-5-dihydro-1h-pyrazole-4-5-diol-pa3206560
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PA 32 06560

3-Methyl-1-phenyl-4,5-dihydro-1H-pyrazole-4,5-diol


  • Catalogue No.:PA 32 06560

  • CAS :

    NA

  • Molecular Formula : C10H12N2O2

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => 5,5"-dihydroxy-3,3",5'-trimethyl-1,1",2'-triphenyl-4,4",5,5"-tetrahydro-1H,1"H-[4,4':4',4"-terpyrazol]-3'(2'H)-one
    [catalogue_number] => PA 32 0061000
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 522.61
    [form] => C30H30N6O3
    [cas] => NA
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PA 32 0061000

5,5"-dihydroxy-3,3",5'-trimethyl-1,1",2'-triphenyl-4,4",5,5"-tetrahydro-1H,1"H-[4,4':4',4"-terpyrazol]-3'(2'H)-one


  • Catalogue No.:PA 32 0061000

  • CAS :

    NA

  • Molecular Formula : C30H30N6O3

  • Molecular Weight : 522.61

stdClass Object
(
    [pname] => 4-Ethyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
    [catalogue_number] => PA 32 0061001
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 202.26
    [form] => C12H14N2O
    [cas] => NA
    [pslug] => 4-ethyl-5-methyl-2-phenyl-2-4-dihydro-3h-pyrazol-3-one-pa320061001
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PA 32 0061001

4-Ethyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one


  • Catalogue No.:PA 32 0061001

  • CAS :

    NA

  • Molecular Formula : C12H14N2O

  • Molecular Weight : 202.26

stdClass Object
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    [pname] => 5-(Hydroxymethyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
    [catalogue_number] => PA 32 0061002
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 190.2
    [form] => C10H10N2O2
    [cas] => NA
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PA 32 0061002

5-(Hydroxymethyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one


  • Catalogue No.:PA 32 0061002

  • CAS :

    NA

  • Molecular Formula : C10H10N2O2

  • Molecular Weight : 190.2

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    [pname] => 4-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic Acid
    [catalogue_number] => PA 32 0061003
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 218.21
    [form] => C11H10N2O3
    [cas] => NA
    [pslug] => 4-methyl-5-oxo-1-phenyl-4-5-dihydro-1h-pyrazole-3-carboxylic-acid-pa320061003
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PA 32 0061003

4-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic Acid


  • Catalogue No.:PA 32 0061003

  • CAS :

    NA

  • Molecular Formula : C11H10N2O3

  • Molecular Weight : 218.21

stdClass Object
(
    [pname] => (E)-3-Methyl-1-phenyl-4-(1-(1-phenylhydrazinyl)buta-1,3-dien-2-yl)-1H-pyrazol-5-ol
    [catalogue_number] => PA 32 0061004
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 332.41
    [form] => C20H20N4O
    [cas] => NA
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PA 32 0061004

(E)-3-Methyl-1-phenyl-4-(1-(1-phenylhydrazinyl)buta-1,3-dien-2-yl)-1H-pyrazol-5-ol


  • Catalogue No.:PA 32 0061004

  • CAS :

    NA

  • Molecular Formula : C20H20N4O

  • Molecular Weight : 332.41

stdClass Object
(
    [pname] => 5-Hydroxy-3,5',5"-trimethyl-1,2',2"-triphenyl-2",4,4",5-tetrahydro-1H,3"H-[4,4':4',4"-terpyrazole]-3',3"(2'H)-dione
    [catalogue_number] => PA 32 0061005
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 520.59
    [form] => C30H28N6O3
    [cas] => NA
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PA 32 0061005

5-Hydroxy-3,5',5"-trimethyl-1,2',2"-triphenyl-2",4,4",5-tetrahydro-1H,3"H-[4,4':4',4"-terpyrazole]-3',3"(2'H)-dione


  • Catalogue No.:PA 32 0061005

  • CAS :

    NA

  • Molecular Formula : C30H28N6O3

  • Molecular Weight : 520.59

stdClass Object
(
    [pname] => 4-(2-Diazenyl-2-oxoethyl)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
    [catalogue_number] => PA 32 0061006
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 244.25
    [form] => C12H12N4O2
    [cas] => NA
    [pslug] => 4-2-diazenyl-2-oxoethyl-5-methyl-2-phenyl-2-4-dihydro-3h-pyrazol-3-one-pa320061006
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PA 32 0061006

4-(2-Diazenyl-2-oxoethyl)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one


  • Catalogue No.:PA 32 0061006

  • CAS :

    NA

  • Molecular Formula : C12H12N4O2

  • Molecular Weight : 244.25

stdClass Object
(
    [pname] => 5-Methyl-2-phenyl-2,4-dihydro-3H,3'H-[4,4'-bipyrazole]-3,3'-dione
    [catalogue_number] => PA 32 0061007
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 254.25
    [form] => C13H10N4O2
    [cas] => NA
    [pslug] => 5-methyl-2-phenyl-2-4-dihydro-3h-3h-4-4-bipyrazole-3-3-dione-pa320061007
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PA 32 0061007

5-Methyl-2-phenyl-2,4-dihydro-3H,3'H-[4,4'-bipyrazole]-3,3'-dione


  • Catalogue No.:PA 32 0061007

  • CAS :

    NA

  • Molecular Formula : C13H10N4O2

  • Molecular Weight : 254.25

stdClass Object
(
    [pname] => 5'-(Hydroxymethyl)-4,5-dimethyl-2,2'-diphenyl-2,2',4,4'-tetrahydro-3H,3'H-[4,4'-bipyrazole]-3,3'-dione
    [catalogue_number] => PA 32 0061008
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 376.42
    [form] => C21H20N4O3
    [cas] => NA
    [pslug] => 5-hydroxymethyl-4-5-dimethyl-2-2-diphenyl-2-2-4-4-tetrahydro-3h-3h-4-4-bipyrazole-3-3-dione-pa320061008
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PA 32 0061008

5'-(Hydroxymethyl)-4,5-dimethyl-2,2'-diphenyl-2,2',4,4'-tetrahydro-3H,3'H-[4,4'-bipyrazole]-3,3'-dione


  • Catalogue No.:PA 32 0061008

  • CAS :

    NA

  • Molecular Formula : C21H20N4O3

  • Molecular Weight : 376.42

stdClass Object
(
    [pname] => 3'-(Hydroxymethyl)-3"-methyl-5,5',5"-trioxo-1,1',1"-triphenyl-1',4,4",5,5',5"-hexahydro-1H,1"H-[4,4':4',4"-terpyrazole]-3-carboxylic Acid
    [catalogue_number] => PA 32 0061009
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 564.56
    [form] => C30H24N6O6
    [cas] => NA
    [pslug] => 3-hydroxymethyl-3-methyl-5-5-5-trioxo-1-1-1-triphenyl-1-4-4-5-5-5-hexahydro-1h-1h-4-4-4-4-terpyrazole-3-carboxylic-acid-pa320061009
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PA 32 0061009

3'-(Hydroxymethyl)-3"-methyl-5,5',5"-trioxo-1,1',1"-triphenyl-1',4,4",5,5',5"-hexahydro-1H,1"H-[4,4':4',4"-terpyrazole]-3-carboxylic Acid


  • Catalogue No.:PA 32 0061009

  • CAS :

    NA

  • Molecular Formula : C30H24N6O6

  • Molecular Weight : 564.56

stdClass Object
(
    [pname] => 5-(Hydroxymethyl)-5',5"-dimethyl-2,2',2"-triphenyl-2,2",4,4"-tetrahydro-3H,3"H-[4,4':4',4"-terpyrazole]-3,3',3"(2'H)-trione
    [catalogue_number] => PA 32 0061010
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 534.58
    [form] => C30H26N6O4
    [cas] => NA
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PA 32 0061010

5-(Hydroxymethyl)-5',5"-dimethyl-2,2',2"-triphenyl-2,2",4,4"-tetrahydro-3H,3"H-[4,4':4',4"-terpyrazole]-3,3',3"(2'H)-trione


  • Catalogue No.:PA 32 0061010

  • CAS :

    NA

  • Molecular Formula : C30H26N6O4

  • Molecular Weight : 534.58

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    [pname] => (E)-2-Oxo-3-(2-phenylhydrazono)butanoic Acid
    [catalogue_number] => PA 32 0061013
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 206.2
    [form] => C10H10N2O3
    [cas] => 1086213-77-5
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PA 32 0061013

(E)-2-Oxo-3-(2-phenylhydrazono)butanoic Acid


  • Catalogue No.:PA 32 0061013

  • CAS :

    1086213-77-5

  • Molecular Formula : C10H10N2O3

  • Molecular Weight : 206.2

stdClass Object
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    [pname] => 2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-2-sulfopropanoic Acid
    [catalogue_number] => PA 32 0061011
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    [chemical_name] => 
    [weight] => 326.32
    [form] => C13H14N2O6S
    [cas] => 1357477-99-6
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PA 32 0061011

2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-2-sulfopropanoic Acid


  • Catalogue No.:PA 32 0061011

  • CAS :

    1357477-99-6

  • Molecular Formula : C13H14N2O6S

  • Molecular Weight : 326.32

stdClass Object
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    [pname] => 2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic Acid
    [catalogue_number] => PA 32 0061012
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 296.34
    [form] => C13H16N2O4S
    [cas] => 1323485-71-7
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PA 32 0061012

2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic Acid


  • Catalogue No.:PA 32 0061012

  • CAS :

    1323485-71-7

  • Molecular Formula : C13H16N2O4S

  • Molecular Weight : 296.34

stdClass Object
(
    [pname] => (Z)-5,5'-Dimethyl-2,2'-diphenyl-[4,4'-bipyrazolylidene]-3,3'(2H,2'H)-dione
    [catalogue_number] => PAI 32 006001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 344.37
    [form] => C20H16N4O2
    [cas] => NA
    [pslug] => z-5-5-dimethyl-2-2-diphenyl-4-4-bipyrazolylidene-3-3-2h-2h-dione-pai32006001
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PAI 32 006001

(Z)-5,5'-Dimethyl-2,2'-diphenyl-[4,4'-bipyrazolylidene]-3,3'(2H,2'H)-dione


  • Catalogue No.:PAI 32 006001

  • CAS :

    NA

  • Molecular Formula : C20H16N4O2

  • Molecular Weight : 344.37

stdClass Object
(
    [pname] => Edaravone Trimer Impurity
    [catalogue_number] => PA 32 0061014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 518.58
    [form] => C30H26N6O3
    [cas] => 68195-63-1
    [pslug] => 68195-63-1-edaravone-trimer-impurity-pa320061014
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PA 32 0061014

Edaravone Trimer Impurity


  • Catalogue No.:PA 32 0061014

  • CAS :

    68195-63-1

  • Molecular Formula : C30H26N6O3

  • Molecular Weight : 518.58

stdClass Object
(
    [pname] => 1-Hydroxy-2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic acid, Sodium Salt
    [catalogue_number] => PA 32 0061018
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 335.33
    [form] => C13H16N2NaO5S
    [cas] => 1322767-62-3
    [pslug] => 1322767-62-3-1-hydroxy-2-3-methyl-5-oxo-1-phenyl-4-5-dihydro-1h-pyrazol-4-yl-propane-2-sulfonic-acid-sodium-salt-pa320061018
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PA 32 0061018

1-Hydroxy-2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic acid, Sodium Salt


  • Catalogue No.:PA 32 0061018

  • CAS :

    1322767-62-3

  • Molecular Formula : C13H16N2NaO5S

  • Molecular Weight : 335.33

stdClass Object
(
    [pname] => 5'-Ethoxy-3,3'-dimethyl-1,1'-diphenyl-1H,1'H-[4,4'-bipyrazol]-5-ol
    [catalogue_number] => PA 32 0061019
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 374.44
    [form] => C22H22N4O2
    [cas] => NA
    [pslug] => 5-ethoxy-3-3-dimethyl-1-1-diphenyl-1h-1h-4-4-bipyrazol-5-ol-pa320061019
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PA 32 0061019

5'-Ethoxy-3,3'-dimethyl-1,1'-diphenyl-1H,1'H-[4,4'-bipyrazol]-5-ol


  • Catalogue No.:PA 32 0061019

  • CAS :

    NA

  • Molecular Formula : C22H22N4O2

  • Molecular Weight : 374.44

stdClass Object
(
    [pname] => Ethyl (E)-3-(2-phenylhydrazono)butanoate
    [catalogue_number] => PA 32 0061017
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 220.27
    [form] => C12H16N2O2
    [cas] => 2061958-41-4
    [pslug] => 2061958-41-4-ethyl-e-3-2-phenylhydrazono-butanoate-pa320061017
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PA 32 0061017

Ethyl (E)-3-(2-phenylhydrazono)butanoate


  • Catalogue No.:PA 32 0061017

  • CAS :

    2061958-41-4

  • Molecular Formula : C12H16N2O2

  • Molecular Weight : 220.27

stdClass Object
(
    [pname] => 1-Hydroxy-2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic Acid
    [catalogue_number] => PA 32 0061016
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 312.34
    [form] => C13H16N2O5S
    [cas] => NA
    [pslug] => 1-hydroxy-2-3-methyl-5-oxo-1-phenyl-4-5-dihydro-1h-pyrazol-4-yl-propane-2-sulfonic-acid-pa320061016
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PA 32 0061016

1-Hydroxy-2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic Acid


  • Catalogue No.:PA 32 0061016

  • CAS :

    NA

  • Molecular Formula : C13H16N2O5S

  • Molecular Weight : 312.34

stdClass Object
(
    [pname] => Sodium 2-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)propane-2-sulfonate
    [catalogue_number] => PA 32 0061015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 318.32
    [form] => C13H15N2NaO4S
    [cas] => NA
    [pslug] => sodium-2-5-hydroxy-3-methyl-1-phenyl-1h-pyrazol-4-yl-propane-2-sulfonate-pa320061015
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PA 32 0061015

Sodium 2-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)propane-2-sulfonate


  • Catalogue No.:PA 32 0061015

  • CAS :

    NA

  • Molecular Formula : C13H15N2NaO4S

  • Molecular Weight : 318.32