efinaconazole

Efinaconazole acts as a 14α-demethylase inhibitor. which indicated in the treatment of fungal infection of the nail, known as onychomycosis.. Reference standards of Efinaconazole API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => (2R)-1-(2,4-Difluorophenyl)-2-(tetrahydro-2H-pyran-2-yloxy)propan-1-one
    [catalogue_number] => PA 05 79630
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 270.27
    [form] => C14H16F2O3
    [cas] => 126918-17-0
    [pslug] => 126918-17-0-2r-1-2-4-difluorophenyl-2-tetrahydro-2h-pyran-2-yloxy-propan-1-one-pa0579630
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PA 05 79630

(2R)-1-(2,4-Difluorophenyl)-2-(tetrahydro-2H-pyran-2-yloxy)propan-1-one

  • Catalogue No.:PA 05 79630

  • CAS :

    126918-17-0

  • Molecular Formula : C14H16F2O3

  • Molecular Weight : 270.27

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Details 
stdClass Object
(
    [pname] => 2-((R)-1-((R)-2-(2,4-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran
    [catalogue_number] => PA 05 79640
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 284.3
    [form] => C15H18F2O3
    [cas] => 135267-12-8
    [pslug] => 135267-12-8-2-r-1-r-2-2-4-difluorophenyl-oxiran-2-yl-ethoxy-tetrahydro-2h-pyran-pa0579640
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PA 05 79640

2-((R)-1-((R)-2-(2,4-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran

  • Catalogue No.:PA 05 79640

  • CAS :

    135267-12-8

  • Molecular Formula : C15H18F2O3

  • Molecular Weight : 284.3

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
    [catalogue_number] => PA 05 79650
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 353.36
    [form] => C17H21F2N3O3
    [cas] => 135133-23-2
    [pslug] => 135133-23-2-2r-3r-2-2-4-difluorophenyl-3-tetrahydro-2h-pyran-2-yl-oxy-1-1h-1-2-4-triazol-1-yl-butan-2-ol-pa0579650
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PA 05 79650

(2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

  • Catalogue No.:PA 05 79650

  • CAS :

    135133-23-2

  • Molecular Formula : C17H21F2N3O3

  • Molecular Weight : 353.36

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate
    [catalogue_number] => PA 05 79670
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 365.35
    [form] => C13H17F2N3O5S
    [cas] => 1175536-50-1
    [pslug] => 1175536-50-1-2r-3r-2-2-4-difluorophenyl-1-1h-1-2-4-triazol-1-yl-2-3-butanediol-methanesulfonate-pa0579670
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PA 05 79670

(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate

  • Catalogue No.:PA 05 79670

  • CAS :

    1175536-50-1

  • Molecular Formula : C13H17F2N3O5S

  • Molecular Weight : 365.35

Enquire
Details 
stdClass Object
(
    [pname] => (2S,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
    [catalogue_number] => PA 05 79690
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 251.23
    [form] => C12H11F2N3O
    [cas] => 135270-10-9
    [pslug] => 135270-10-9-2s-3s-2-2-4-difluorophenyl-3-methyl-2-1h-1-2-4-triazol-1-yl-methyl-oxirane-pa0579690
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PA 05 79690

(2S,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

  • Catalogue No.:PA 05 79690

  • CAS :

    135270-10-9

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.23

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
    [catalogue_number] => PA 05 79700
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 251.23
    [form] => C12H11F2N3O
    [cas] => 135270-13-2
    [pslug] => 135270-13-2-2r-3r-2-2-4-difluorophenyl-3-methyl-2-1h-1-2-4-triazol-1-yl-methyl-oxirane-pa0579700
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PA 05 79700

(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

  • Catalogue No.:PA 05 79700

  • CAS :

    135270-13-2

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.23

Enquire
Details 
stdClass Object
(
    [pname] => (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
    [catalogue_number] => PA 05 79710
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 251.23
    [form] => C12H11F2N3O
    [cas] => 135270-07-4
    [pslug] => 135270-07-4-2s-3r-2-2-4-difluorophenyl-3-methyl-2-1h-1-2-4-triazol-1-yl-methyl-oxirane-pa0579710
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PA 05 79710

(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

  • Catalogue No.:PA 05 79710

  • CAS :

    135270-07-4

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.23

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Details 
stdClass Object
(
    [pname] => 1-((R)-1-((R)-8-((1H-1,2,4-Triazol-1-yl)methyl)-4-fluoro-7-oxabicyclo[4.2.0]octa-1(6),2,4-trien-8-yl)ethyl)-4-methylenepiperidine
    [catalogue_number] => PA 05 79730
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 328.38
    [form] => C18H21FN4O
    [cas] => NA
    [pslug] => 1-r-1-r-8-1h-1-2-4-triazol-1-yl-methyl-4-fluoro-7-oxabicyclo-4-2-0-octa-1-6-2-4-trien-8-yl-ethyl-4-methylenepiperidine-pa0579730
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PA 05 79730

1-((R)-1-((R)-8-((1H-1,2,4-Triazol-1-yl)methyl)-4-fluoro-7-oxabicyclo[4.2.0]octa-1(6),2,4-trien-8-yl)ethyl)-4-methylenepiperidine

  • Catalogue No.:PA 05 79730

  • CAS :

    NA

  • Molecular Formula : C18H21FN4O

  • Molecular Weight : 328.38

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Details 
stdClass Object
(
    [pname] => Des-4-methylenepiperidine Efinaconazole
    [catalogue_number] => PA 05 0791000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 269.25
    [form] => C12H13F2N3O2
    [cas] => 241479-72-1
    [pslug] => 241479-72-1-des-4-methylenepiperidine-efinaconazole-pa050791000
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PA 05 0791000

Des-4-methylenepiperidine Efinaconazole

  • Catalogue No.:PA 05 0791000

  • CAS :

    241479-72-1

  • Molecular Formula : C12H13F2N3O2

  • Molecular Weight : 269.25

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Details 
stdClass Object
(
    [pname] => (2S,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
    [catalogue_number] => PA 05 0791001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 278.26
    [form] => C13H12F2N4O
    [cas] => 241479-74-3
    [pslug] => 241479-74-3-2s-3r-3-2-5-difluorophenyl-3-hydroxy-2-methyl-4-1h-1-2-4-triazol-1-yl-butanenitrile-pa050791001
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PA 05 0791001

(2S,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile

  • Catalogue No.:PA 05 0791001

  • CAS :

    241479-74-3

  • Molecular Formula : C13H12F2N4O

  • Molecular Weight : 278.26

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Details 
stdClass Object
(
    [pname] => (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanamide
    [catalogue_number] => PA 05 0791002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 296.28
    [form] => C13H14F2N4O2
    [cas] => 241479-75-4
    [pslug] => 241479-75-4-2r-3r-3-2-5-difluorophenyl-3-hydroxy-2-methyl-4-1h-1-2-4-triazol-1-yl-butanamide-pa050791002
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PA 05 0791002

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanamide

  • Catalogue No.:PA 05 0791002

  • CAS :

    241479-75-4

  • Molecular Formula : C13H14F2N4O2

  • Molecular Weight : 296.28

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Details 
stdClass Object
(
    [pname] => 1-(((2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
    [catalogue_number] => PA 05 0791003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 251.24
    [form] => C12H11F2N3O
    [cas] => 127000-90-2
    [pslug] => 127000-90-2-1-2r-3s-2-2-4-difluorophenyl-3-methyloxiran-2-yl-methyl-1h-1-2-4-triazole-pa050791003
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PA 05 0791003

1-(((2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole

  • Catalogue No.:PA 05 0791003

  • CAS :

    127000-90-2

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.24

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Details 
stdClass Object
(
    [pname] => Efinaconazole 4-Desfluoro Impurity
    [catalogue_number] => PA 05 0791004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 330.41
    [form] => C18H23FN4O
    [cas] => NA
    [pslug] => efinaconazole-4-desfluoro-impurity-pa050791004
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PA 05 0791004

Efinaconazole 4-Desfluoro Impurity

  • Catalogue No.:PA 05 0791004

  • CAS :

    NA

  • Molecular Formula : C18H23FN4O

  • Molecular Weight : 330.41

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-Phenyl-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
    [catalogue_number] => PA 05 0791005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 233.27
    [form] => C12H15N3O2
    [cas] => NA
    [pslug] => 2r-3r-2-phenyl-1-1h-1-2-4-triazol-1-yl-butane-2-3-diol-pa050791005
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PA 05 0791005

(2R,3R)-2-Phenyl-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

  • Catalogue No.:PA 05 0791005

  • CAS :

    NA

  • Molecular Formula : C12H15N3O2

  • Molecular Weight : 233.27

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Details 
stdClass Object
(
    [pname] => (2S,3S)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
    [catalogue_number] => PA 05 0791006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 278.26
    [form] => C13H12F2N4O
    [cas] => 2001051-99-4
    [pslug] => 2001051-99-4-2s-3s-3-2-5-difluorophenyl-3-hydroxy-2-methyl-4-1h-1-2-4-triazol-1-yl-butanenitrile-pa050791006
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PA 05 0791006

(2S,3S)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile

  • Catalogue No.:PA 05 0791006

  • CAS :

    2001051-99-4

  • Molecular Formula : C13H12F2N4O

  • Molecular Weight : 278.26

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(4-Fluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
    [catalogue_number] => PA 05 0791007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 330.41
    [form] => C18H23FN4O
    [cas] => 2055038-64-5
    [pslug] => 2055038-64-5-2r-3r-2-4-fluorophenyl-3-4-methylenepiperidin-1-yl-1-1h-1-2-4-triazol-1-yl-butan-2-ol-pa050791007
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PA 05 0791007

(2R,3R)-2-(4-Fluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

  • Catalogue No.:PA 05 0791007

  • CAS :

    2055038-64-5

  • Molecular Formula : C18H23FN4O

  • Molecular Weight : 330.41

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Details 
stdClass Object
(
    [pname] => (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one
    [catalogue_number] => PA 05 0791009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 186.16
    [form] => C9H8F2O2
    [cas] => 126918-16-9
    [pslug] => 126918-16-9-r-1-2-4-difluorophenyl-2-hydroxypropan-1-one-pa050791009
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PA 05 0791009

(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one

  • Catalogue No.:PA 05 0791009

  • CAS :

    126918-16-9

  • Molecular Formula : C9H8F2O2

  • Molecular Weight : 186.16

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CPHI INDIA- 28, 30 November