efinaconazole

Impurities - Efinaconazole acts as a 14α-demethylase inhibitor. which indicated in the treatment of fungal infection of the nail, known as onychomycosis.. Reference standards of Efinaconazole API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => (2R)-1-(2,4-Difluorophenyl)-2-(tetrahydro-2H-pyran-2-yloxy)propan-1-one
    [catalogue_number] => PA 05 79630
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 270.27
    [form] => C14H16F2O3
    [cas] => 126918-17-0
    [pslug] => 126918-17-0-2r-1-2-4-difluorophenyl-2-tetrahydro-2h-pyran-2-yloxy-propan-1-one-pa0579630
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PA 05 79630
PA 05 79630

(2R)-1-(2,4-Difluorophenyl)-2-(tetrahydro-2H-pyran-2-yloxy)propan-1-one

  • Catalogue No.:PA 05 79630

  • CAS :

    126918-17-0

  • Molecular Formula : C14H16F2O3

  • Molecular Weight : 270.27

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Details 
stdClass Object
(
    [pname] => 2-((R)-1-((R)-2-(2,4-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran
    [catalogue_number] => PA 05 79640
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 284.3
    [form] => C15H18F2O3
    [cas] => 135267-12-8
    [pslug] => 135267-12-8-2-r-1-r-2-2-4-difluorophenyl-oxiran-2-yl-ethoxy-tetrahydro-2h-pyran-pa0579640
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PA 05 79640
PA 05 79640

2-((R)-1-((R)-2-(2,4-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran

  • Catalogue No.:PA 05 79640

  • CAS :

    135267-12-8

  • Molecular Formula : C15H18F2O3

  • Molecular Weight : 284.3

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
    [catalogue_number] => PA 05 79650
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 353.36
    [form] => C17H21F2N3O3
    [cas] => 135133-23-2
    [pslug] => 135133-23-2-2r-3r-2-2-4-difluorophenyl-3-tetrahydro-2h-pyran-2-yl-oxy-1-1h-1-2-4-triazol-1-yl-butan-2-ol-pa0579650
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PA 05 79650
PA 05 79650

(2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

  • Catalogue No.:PA 05 79650

  • CAS :

    135133-23-2

  • Molecular Formula : C17H21F2N3O3

  • Molecular Weight : 353.36

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate
    [catalogue_number] => PA 05 79670
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 365.35
    [form] => C13H17F2N3O5S
    [cas] => 1175536-50-1
    [pslug] => 1175536-50-1-2r-3r-2-2-4-difluorophenyl-1-1h-1-2-4-triazol-1-yl-2-3-butanediol-methanesulfonate-pa0579670
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PA 05 79670
PA 05 79670

(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate

  • Catalogue No.:PA 05 79670

  • CAS :

    1175536-50-1

  • Molecular Formula : C13H17F2N3O5S

  • Molecular Weight : 365.35

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Details 
stdClass Object
(
    [pname] => (2S,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
    [catalogue_number] => PA 05 79690
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 251.23
    [form] => C12H11F2N3O
    [cas] => 135270-10-9
    [pslug] => 135270-10-9-2s-3s-2-2-4-difluorophenyl-3-methyl-2-1h-1-2-4-triazol-1-yl-methyl-oxirane-pa0579690
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PA 05 79690
PA 05 79690

(2S,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

  • Catalogue No.:PA 05 79690

  • CAS :

    135270-10-9

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.23

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
    [catalogue_number] => PA 05 79700
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 251.23
    [form] => C12H11F2N3O
    [cas] => 135270-13-2
    [pslug] => 135270-13-2-2r-3r-2-2-4-difluorophenyl-3-methyl-2-1h-1-2-4-triazol-1-yl-methyl-oxirane-pa0579700
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PA 05 79700
PA 05 79700

(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

  • Catalogue No.:PA 05 79700

  • CAS :

    135270-13-2

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.23

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Details 
stdClass Object
(
    [pname] => (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
    [catalogue_number] => PA 05 79710
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 251.23
    [form] => C12H11F2N3O
    [cas] => 135270-07-4
    [pslug] => 135270-07-4-2s-3r-2-2-4-difluorophenyl-3-methyl-2-1h-1-2-4-triazol-1-yl-methyl-oxirane-pa0579710
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PA 05 79710
PA 05 79710

(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

  • Catalogue No.:PA 05 79710

  • CAS :

    135270-07-4

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.23

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Details 
stdClass Object
(
    [pname] => 1-((R)-1-((R)-8-((1H-1,2,4-Triazol-1-yl)methyl)-4-fluoro-7-oxabicyclo[4.2.0]octa-1(6),2,4-trien-8-yl)ethyl)-4-methylenepiperidine
    [catalogue_number] => PA 05 79730
    [category_ids] => ,80,89,75,70,82,
    [chemical_name] => 
    [weight] => 328.38
    [form] => C18H21FN4O
    [cas] => NA
    [pslug] => 1-r-1-r-8-1h-1-2-4-triazol-1-yl-methyl-4-fluoro-7-oxabicyclo-4-2-0-octa-1-6-2-4-trien-8-yl-ethyl-4-methylenepiperidine-pa0579730
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PA 05 79730
PA 05 79730

1-((R)-1-((R)-8-((1H-1,2,4-Triazol-1-yl)methyl)-4-fluoro-7-oxabicyclo[4.2.0]octa-1(6),2,4-trien-8-yl)ethyl)-4-methylenepiperidine

  • Catalogue No.:PA 05 79730

  • CAS :

    NA

  • Molecular Formula : C18H21FN4O

  • Molecular Weight : 328.38

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Details 
stdClass Object
(
    [pname] => Des-4-methylenepiperidine Efinaconazole
    [catalogue_number] => PA 05 0791000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 269.25
    [form] => C12H13F2N3O2
    [cas] => 241479-72-1
    [pslug] => 241479-72-1-des-4-methylenepiperidine-efinaconazole-pa050791000
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PA 05 0791000
PA 05 0791000

Des-4-methylenepiperidine Efinaconazole

  • Catalogue No.:PA 05 0791000

  • CAS :

    241479-72-1

  • Molecular Formula : C12H13F2N3O2

  • Molecular Weight : 269.25

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Details 
stdClass Object
(
    [pname] => (2S,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
    [catalogue_number] => PA 05 0791001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 278.26
    [form] => C13H12F2N4O
    [cas] => 241479-74-3
    [pslug] => 241479-74-3-2s-3r-3-2-5-difluorophenyl-3-hydroxy-2-methyl-4-1h-1-2-4-triazol-1-yl-butanenitrile-pa050791001
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PA 05 0791001
PA 05 0791001

(2S,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile

  • Catalogue No.:PA 05 0791001

  • CAS :

    241479-74-3

  • Molecular Formula : C13H12F2N4O

  • Molecular Weight : 278.26

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Details 
stdClass Object
(
    [pname] => (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanamide
    [catalogue_number] => PA 05 0791002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 296.28
    [form] => C13H14F2N4O2
    [cas] => 241479-75-4
    [pslug] => 241479-75-4-2r-3r-3-2-5-difluorophenyl-3-hydroxy-2-methyl-4-1h-1-2-4-triazol-1-yl-butanamide-pa050791002
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PA 05 0791002
PA 05 0791002

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanamide

  • Catalogue No.:PA 05 0791002

  • CAS :

    241479-75-4

  • Molecular Formula : C13H14F2N4O2

  • Molecular Weight : 296.28

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Details 
stdClass Object
(
    [pname] => 1-(((2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
    [catalogue_number] => PA 05 0791003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 251.24
    [form] => C12H11F2N3O
    [cas] => 127000-90-2
    [pslug] => 127000-90-2-1-2r-3s-2-2-4-difluorophenyl-3-methyloxiran-2-yl-methyl-1h-1-2-4-triazole-pa050791003
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PA 05 0791003
PA 05 0791003

1-(((2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole

  • Catalogue No.:PA 05 0791003

  • CAS :

    127000-90-2

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.24

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Details 
stdClass Object
(
    [pname] => Efinaconazole 4-Desfluoro Impurity
    [catalogue_number] => PA 05 0791004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 330.41
    [form] => C18H23FN4O
    [cas] => NA
    [pslug] => efinaconazole-4-desfluoro-impurity-pa050791004
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PA 05 0791004
PA 05 0791004

Efinaconazole 4-Desfluoro Impurity

  • Catalogue No.:PA 05 0791004

  • CAS :

    NA

  • Molecular Formula : C18H23FN4O

  • Molecular Weight : 330.41

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-Phenyl-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
    [catalogue_number] => PA 05 0791005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 233.27
    [form] => C12H15N3O2
    [cas] => NA
    [pslug] => 2r-3r-2-phenyl-1-1h-1-2-4-triazol-1-yl-butane-2-3-diol-pa050791005
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PA 05 0791005
PA 05 0791005

(2R,3R)-2-Phenyl-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

  • Catalogue No.:PA 05 0791005

  • CAS :

    NA

  • Molecular Formula : C12H15N3O2

  • Molecular Weight : 233.27

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Details 
stdClass Object
(
    [pname] => (2S,3S)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
    [catalogue_number] => PA 05 0791006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 278.26
    [form] => C13H12F2N4O
    [cas] => 2001051-99-4
    [pslug] => 2001051-99-4-2s-3s-3-2-5-difluorophenyl-3-hydroxy-2-methyl-4-1h-1-2-4-triazol-1-yl-butanenitrile-pa050791006
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PA 05 0791006
PA 05 0791006

(2S,3S)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile

  • Catalogue No.:PA 05 0791006

  • CAS :

    2001051-99-4

  • Molecular Formula : C13H12F2N4O

  • Molecular Weight : 278.26

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Details 
stdClass Object
(
    [pname] => (2R,3R)-2-(4-Fluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
    [catalogue_number] => PA 05 0791007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 330.41
    [form] => C18H23FN4O
    [cas] => 2055038-64-5
    [pslug] => 2055038-64-5-2r-3r-2-4-fluorophenyl-3-4-methylenepiperidin-1-yl-1-1h-1-2-4-triazol-1-yl-butan-2-ol-pa050791007
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PA 05 0791007
PA 05 0791007

(2R,3R)-2-(4-Fluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

  • Catalogue No.:PA 05 0791007

  • CAS :

    2055038-64-5

  • Molecular Formula : C18H23FN4O

  • Molecular Weight : 330.41

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Details 
stdClass Object
(
    [pname] => (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one
    [catalogue_number] => PA 05 0791009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 186.16
    [form] => C9H8F2O2
    [cas] => 126918-16-9
    [pslug] => 126918-16-9-r-1-2-4-difluorophenyl-2-hydroxypropan-1-one-pa050791009
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PA 05 0791009
PA 05 0791009

(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one

  • Catalogue No.:PA 05 0791009

  • CAS :

    126918-16-9

  • Molecular Formula : C9H8F2O2

  • Molecular Weight : 186.16

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