A selective and reversible inhibitor of enzyme catechol-O-methyltransferase (COMT), it is used for the treatment of Parkinson's disease. It is used in addition to levodopa. Reference standards of Entacapone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Entacapone - Impurity B [catalogue_number] => PA 05 06020 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 278.22 [form] => C12H10N2O6 [cas] => 1215039-66-9 [pslug] => 1215039-66-9-entacapone-impurity-b-pa0506020 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06020
CAS :
Molecular Formula : C12H10N2O6
Molecular Weight : 278.22
stdClass Object ( [pname] => Entacapone - Impurity C [catalogue_number] => PA 05 06030 [category_ids] => ,80,75,78,70,82, [chemical_name] => [weight] => 183.12 [form] => C7H5NO5 [cas] => 116313-85-0 [pslug] => 116313-85-0-entacapone-impurity-c-pa0506030 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06030
Molecular Formula : C7H5NO5
Molecular Weight : 183.12
stdClass Object ( [pname] => Entacapone - Impurity D [catalogue_number] => PA 05 06040 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 333.34 [form] => C16H19N3O5 [cas] => 857629-79-9 [pslug] => 857629-79-9-entacapone-impurity-d-pa0506040 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06040
Molecular Formula : C16H19N3O5
Molecular Weight : 333.34
stdClass Object ( [pname] => Entacapone - Impurity E [catalogue_number] => PA 05 06050 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 200.11 [form] => C6H4N2O6 [cas] => 7659-29-2 [pslug] => 7659-29-2-entacapone-impurity-e-pa0506050 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06050
Molecular Formula : C6H4N2O6
Molecular Weight : 200.11
stdClass Object ( [pname] => Entacapone - Impurity F [catalogue_number] => PA 05 06060 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 250.16 [form] => C10H6N2O6 [cas] => 160391-70-8 [pslug] => 160391-70-8-entacapone-impurity-f-pa0506060 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06060
Molecular Formula : C10H6N2O6
Molecular Weight : 250.16
stdClass Object ( [pname] => Entacapone - Impurity G [catalogue_number] => PA 05 06070 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 263.21 [form] => C11H9N3O5 [cas] => 1364322-41-7 [pslug] => 1364322-41-7-entacapone-impurity-g-pa0506070 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06070
Molecular Formula : C11H9N3O5
Molecular Weight : 263.21
stdClass Object ( [pname] => Entacapone - Impurity H [catalogue_number] => PA 05 06080 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 317.30 [form] => C15H15N3O5 [cas] => 1150310-15-8 [pslug] => 1150310-15-8-entacapone-impurity-h-pa0506080 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06080
Molecular Formula : C15H15N3O5
Molecular Weight : 317.30
stdClass Object ( [pname] => Entacapone - Impurity I [catalogue_number] => PA 05 06090 [category_ids] => 82,80,78,75,70 [chemical_name] => [weight] => 292.24 [form] => C13H12N2O6 [cas] => 1364322-42-8 [pslug] => 1364322-42-8-entacapone-impurity-i-pa0506090 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06090
Molecular Formula : C13H12N2O6
Molecular Weight : 292.24
stdClass Object ( [pname] => Entacapone 3-o-glucuronide [catalogue_number] => PA 05 0061000 [category_ids] => ,70,75,76,78,82,95, [chemical_name] => [weight] => 481.41 [form] => C20H23N3O11 [cas] => 158069-75-1 [pslug] => 158069-75-1-entacapone-3-o-glucuronide-pa050061000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061000
Molecular Formula : C20H23N3O11
Molecular Weight : 481.41
stdClass Object ( [pname] => 3,4-Dihydroxy-5-nitrobenzoic acid [catalogue_number] => PA 05 0061001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 199.12 [form] => C7H5NO6 [cas] => 84211-30-3 [pslug] => 84211-30-3-3-4-dihydroxy-5-nitrobenzoic-acid-pa050061001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061001
Molecular Formula : C7H5NO6
Molecular Weight : 199.12
stdClass Object ( [pname] => (E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylic acid [catalogue_number] => PA 05 0061002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 264.19 [form] => C11H8N2O6 [cas] => 1202160-40-4 [pslug] => 1202160-40-4-e-2-cyano-3-4-hydroxy-3-methoxy-5-nitrophenyl-acrylic-acid-pa050061002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061002
Molecular Formula : C11H8N2O6
Molecular Weight : 264.19
stdClass Object ( [pname] => (E)-3-O-Methyl Entacapone [catalogue_number] => PA 05 0061003 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 319.32 [form] => C15H17N3O5 [cas] => 857629-78-8 [pslug] => 857629-78-8-e-3-o-methyl-entacapone-pa050061003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061003
Molecular Formula : C15H17N3O5
Molecular Weight : 319.32
stdClass Object ( [pname] => (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-ethylacrylamide [catalogue_number] => PA 05 0061004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 277.24 [form] => C12H11N3O5 [cas] => 150995-46-3 [pslug] => 150995-46-3-e-2-cyano-3-3-4-dihydroxy-5-nitrophenyl-n-ethylacrylamide-pa050061004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061004
Molecular Formula : C12H11N3O5
Molecular Weight : 277.24
stdClass Object ( [pname] => (E/Z)-3-O-Methyl Entacapone [catalogue_number] => PA 05 0061005 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 319.32 [form] => C15H17N3O5 [cas] => 146698-91-1 [pslug] => 146698-91-1-e-z-3-o-methyl-entacapone-pa050061005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061005
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