gefitinib

Impurities - Gefitinib is used to treat lung cancer. Acting in a similar manner to erlotinib gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. Reference standards of Gefitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => O-Desmorpholinopropyl Gefitinib
    [catalogue_number] => PA 07 24540
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 319.72
    [form] => C15H11ClFN3O2
    [cas] => 184475-71-6
    [pslug] => 184475-71-6-o-desmorpholinopropyl-gefitinib-pa0724540
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PA 07 24540
PA 07 24540

O-Desmorpholinopropyl Gefitinib

  • Catalogue No.:PA 07 24540

  • CAS :

    184475-71-6

  • Molecular Formula : C15H11ClFN3O2

  • Molecular Weight : 319.72

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Details 
stdClass Object
(
    [pname] => N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine
    [catalogue_number] => PA 07 24550
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 462.9
    [form] => C22H24ClFN4O4
    [cas] => NA
    [pslug] => n-3-chloro-4-fluorophenyl-n-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-yl-hydroxylamine-pa0724550
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PA 07 24550
PA 07 24550

N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine

  • Catalogue No.:PA 07 24550

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O4

  • Molecular Weight : 462.9

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Details 
stdClass Object
(
    [pname] => 4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide
    [catalogue_number] => PA 07 24560
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 478.9
    [form] => C22H24ClFN4O5
    [cas] => NA
    [pslug] => 4-3-4-3-chloro-4-fluorophenyl-hydroxy-amino-7-methoxyquinazolin-6-yl-oxy-propyl-morpholine-4-oxide-pa0724560
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PA 07 24560
PA 07 24560

4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide

  • Catalogue No.:PA 07 24560

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O5

  • Molecular Weight : 478.9

Enquire
Details 
stdClass Object
(
    [pname] => N-(3-Morpholinopropyl) Gefitinib
    [catalogue_number] => PA 07 24580
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 574.09
    [form] => C29H37ClFN5O4
    [cas] => 1502829-45-9
    [pslug] => 1502829-45-9-n-3-morpholinopropyl-gefitinib-pa0724580
    [latest_product] => 0
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PA 07 24580
PA 07 24580

N-(3-Morpholinopropyl) Gefitinib

  • Catalogue No.:PA 07 24580

  • CAS :

    1502829-45-9

  • Molecular Formula : C29H37ClFN5O4

  • Molecular Weight : 574.09

Enquire
Details 
stdClass Object
(
    [pname] => N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
    [catalogue_number] => PA 07 24590
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 333.74
    [form] => C16H13ClFN3O2
    [cas] => 153437-78-6
    [pslug] => 153437-78-6-n-3-chloro-4-fluorophenyl-6-7-dimethoxyquinazolin-4-amine-pa0724590
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PA 07 24590
PA 07 24590

N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

  • Catalogue No.:PA 07 24590

  • CAS :

    153437-78-6

  • Molecular Formula : C16H13ClFN3O2

  • Molecular Weight : 333.74

Enquire
Details 
stdClass Object
(
    [pname] => N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24600
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 412.46
    [form] => C22H25FN4O3
    [cas] => 2254241-82-0
    [pslug] => 2254241-82-0-n-4-fluorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-amine-pa0724600
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PA 07 24600
PA 07 24600

N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24600

  • CAS :

    2254241-82-0

  • Molecular Formula : C22H25FN4O3

  • Molecular Weight : 412.46

Enquire
Details 
stdClass Object
(
    [pname] => 4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
    [catalogue_number] => PA 07 24610
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 337.8
    [form] => C16H20ClN3O3
    [cas] => 199327-59-8
    [pslug] => 199327-59-8-4-3-4-chloro-7-methoxyquinazolin-6-yl-oxy-propyl-morpholine-pa0724610
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PA 07 24610
PA 07 24610

4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine

  • Catalogue No.:PA 07 24610

  • CAS :

    199327-59-8

  • Molecular Formula : C16H20ClN3O3

  • Molecular Weight : 337.8

Enquire
Details 
stdClass Object
(
    [pname] => O-Desmethyl Gefitinib
    [catalogue_number] => PA 07 24620
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 432.88
    [form] => C21H22ClFN4O3
    [cas] => 847949-49-9
    [pslug] => 847949-49-9-o-desmethyl-gefitinib-pa0724620
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PA 07 24620
PA 07 24620

O-Desmethyl Gefitinib

  • Catalogue No.:PA 07 24620

  • CAS :

    847949-49-9

  • Molecular Formula : C21H22ClFN4O3

  • Molecular Weight : 432.88

Enquire
Details 
stdClass Object
(
    [pname] => N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24630
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 430.45
    [form] => C22H24F2N4O3
    [cas] => 184475-50-1
    [pslug] => 184475-50-1-n-3-4-difluorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-amine-pa0724630
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PA 07 24630
PA 07 24630

N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24630

  • CAS :

    184475-50-1

  • Molecular Formula : C22H24F2N4O3

  • Molecular Weight : 430.45

Enquire
Details 
stdClass Object
(
    [pname] => 4-Defluoro-4-hydroxy Gefitinib
    [catalogue_number] => PA 07 24640
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 444.91
    [form] => C22H25ClN4O4
    [cas] => 847949-50-2
    [pslug] => 847949-50-2-4-defluoro-4-hydroxy-gefitinib-pa0724640
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PA 07 24640
PA 07 24640

4-Defluoro-4-hydroxy Gefitinib

  • Catalogue No.:PA 07 24640

  • CAS :

    847949-50-2

  • Molecular Formula : C22H25ClN4O4

  • Molecular Weight : 444.91

Enquire
Details 
stdClass Object
(
    [pname] => N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24650
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 463.36
    [form] => C22H24Cl2N4O3
    [cas] => 2089650-13-3
    [pslug] => 2089650-13-3-n-3-4-dichlorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-amine-pa0724650
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PA 07 24650
PA 07 24650

N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24650

  • CAS :

    2089650-13-3

  • Molecular Formula : C22H24Cl2N4O3

  • Molecular Weight : 463.36

Enquire
Details 
stdClass Object
(
    [pname] => 3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate
    [catalogue_number] => PA 07 24660
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 362.74
    [form] => C17H12ClFN2O4
    [cas] => 2512211-98-0
    [pslug] => 2512211-98-0-3-3-chloro-4-fluorophenyl-7-methoxy-4-oxo-3-4-dihydroquinazolin-6-yl-acetate-pa0724660
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PA 07 24660
PA 07 24660

3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate

  • Catalogue No.:PA 07 24660

  • CAS :

    2512211-98-0

  • Molecular Formula : C17H12ClFN2O4

  • Molecular Weight : 362.74

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Details 
stdClass Object
(
    [pname] => 3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one
    [catalogue_number] => PA 07 24670
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 447.89
    [form] => C22H23ClFN3O4
    [cas] => 1608115-59-8
    [pslug] => 1608115-59-8-3-3-chloro-4-fluorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-3h-one-pa0724670
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PA 07 24670
PA 07 24670

3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one

  • Catalogue No.:PA 07 24670

  • CAS :

    1608115-59-8

  • Molecular Formula : C22H23ClFN3O4

  • Molecular Weight : 447.89

Enquire
Details 
stdClass Object
(
    [pname] => 7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24680
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 485.77
    [form] => C21H20Cl3FN4O2
    [cas] => 2921918-23-0
    [pslug] => 2921918-23-0-7-8-dichloro-n-3-chloro-4-fluorophenyl-6-3-morpholinopropoxy-quinazolin-4-amine-pa0724680
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PA 07 24680
PA 07 24680

7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24680

  • CAS :

    2921918-23-0

  • Molecular Formula : C21H20Cl3FN4O2

  • Molecular Weight : 485.77

Enquire
Details 
stdClass Object
(
    [pname] => 4-chloro-7-methoxyquinazolin-6-yl acetate
    [catalogue_number] => PA 07 0241000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 252.65
    [form] => C11H9ClN2O3
    [cas] => 230955-75-6
    [pslug] => 230955-75-6-4-chloro-7-methoxyquinazolin-6-yl-acetate-pa070241000
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PA 07 0241000
PA 07 0241000

4-chloro-7-methoxyquinazolin-6-yl acetate

  • Catalogue No.:PA 07 0241000

  • CAS :

    230955-75-6

  • Molecular Formula : C11H9ClN2O3

  • Molecular Weight : 252.65

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Details 
stdClass Object
(
    [pname] => Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate
    [catalogue_number] => PA 07 0241001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 324.38
    [form] => C16H24N2O5
    [cas] => 214472-41-0
    [pslug] => 214472-41-0-methyl-2-amino-4-methoxy-5-3-morpholinopropoxy-benzoate-pa070241001
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PA 07 0241001
PA 07 0241001

Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate

  • Catalogue No.:PA 07 0241001

  • CAS :

    214472-41-0

  • Molecular Formula : C16H24N2O5

  • Molecular Weight : 324.38

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Details 
stdClass Object
(
    [pname] => Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate
    [catalogue_number] => PA 07 0241002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 354.36
    [form] => C16H22N2O7
    [cas] => 214472-37-4
    [pslug] => 214472-37-4-methyl-4-methoxy-5-3-morpholinopropoxy-2-nitrobenzoate-pa070241002
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PA 07 0241002
PA 07 0241002

Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate

  • Catalogue No.:PA 07 0241002

  • CAS :

    214472-37-4

  • Molecular Formula : C16H22N2O7

  • Molecular Weight : 354.36

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Details 
stdClass Object
(
    [pname] => Gefitinib Nitroso Impurity
    [catalogue_number] => PA 07 0241003
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 475.91
    [form] => C22H23ClFN5O4
    [cas] => NA
    [pslug] => gefitinib-nitroso-impurity-pa070241003
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PA 07 0241003
PA 07 0241003

Gefitinib Nitroso Impurity

  • Catalogue No.:PA 07 0241003

  • CAS :

    NA

  • Molecular Formula : C22H23ClFN5O4

  • Molecular Weight : 475.91

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