gefitinib
Gefitinib is used to treat lung cancer. Acting in a similar manner to erlotinib gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. Reference standards of Gefitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => O-Desmorpholinopropyl Gefitinib
[catalogue_number] => PA 07 24540
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[chemical_name] =>
[weight] => 319.72
[form] => C15H11ClFN3O2
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O-Desmorpholinopropyl Gefitinib
Catalogue No.:PA 07 24540
Molecular Formula : C15H11ClFN3O2
Molecular Weight : 319.72
stdClass Object
(
[pname] => N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine
[catalogue_number] => PA 07 24550
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[chemical_name] =>
[weight] => 462.9
[form] => C22H24ClFN4O4
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N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine
stdClass Object
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[pname] => 4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide
[catalogue_number] => PA 07 24560
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 478.9
[form] => C22H24ClFN4O5
[cas] => NA
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4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide
stdClass Object
(
[pname] => N-(3-Morpholinopropyl) Gefitinib
[catalogue_number] => PA 07 24580
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 574.09
[form] => C29H37ClFN5O4
[cas] => 1502829-45-9
[pslug] => 1502829-45-9-n-3-morpholinopropyl-gefitinib-pa0724580
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N-(3-Morpholinopropyl) Gefitinib
Catalogue No.:PA 07 24580
Molecular Formula : C29H37ClFN5O4
Molecular Weight : 574.09
stdClass Object
(
[pname] => N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
[catalogue_number] => PA 07 24590
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 333.74
[form] => C16H13ClFN3O2
[cas] => 153437-78-6
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N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Catalogue No.:PA 07 24590
Molecular Formula : C16H13ClFN3O2
Molecular Weight : 333.74
stdClass Object
(
[pname] => N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 24600
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 412.46
[form] => C22H25FN4O3
[cas] => 2254241-82-0
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N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24600
Molecular Formula : C22H25FN4O3
Molecular Weight : 412.46
stdClass Object
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[pname] => 4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
[catalogue_number] => PA 07 24610
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[chemical_name] =>
[weight] => 337.8
[form] => C16H20ClN3O3
[cas] => 199327-59-8
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4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
stdClass Object
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[pname] => O-Desmethyl Gefitinib
[catalogue_number] => PA 07 24620
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 432.88
[form] => C21H22ClFN4O3
[cas] => 847949-49-9
[pslug] => 847949-49-9-o-desmethyl-gefitinib-pa0724620
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Catalogue No.:PA 07 24620
Molecular Formula : C21H22ClFN4O3
Molecular Weight : 432.88
stdClass Object
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[pname] => N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 24630
[category_ids] => 82,78,76,75,70
[chemical_name] =>
[weight] => 430.45
[form] => C22H24F2N4O3
[cas] => 184475-50-1
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N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24630
Molecular Formula : C22H24F2N4O3
Molecular Weight : 430.45
stdClass Object
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[pname] => 4-Defluoro-4-hydroxy Gefitinib
[catalogue_number] => PA 07 24640
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[chemical_name] =>
[weight] => 444.91
[form] => C22H25ClN4O4
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4-Defluoro-4-hydroxy Gefitinib
Catalogue No.:PA 07 24640
Molecular Formula : C22H25ClN4O4
Molecular Weight : 444.91
stdClass Object
(
[pname] => N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 24650
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[weight] => 463.36
[form] => C22H24Cl2N4O3
[cas] => 2089650-13-3
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N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24650
Molecular Formula : C22H24Cl2N4O3
Molecular Weight : 463.36
stdClass Object
(
[pname] => 3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate
[catalogue_number] => PA 07 24660
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[chemical_name] =>
[weight] => 362.74
[form] => C17H12ClFN2O4
[cas] => 2512211-98-0
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3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate
Catalogue No.:PA 07 24660
Molecular Formula : C17H12ClFN2O4
Molecular Weight : 362.74
stdClass Object
(
[pname] => 3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one
[catalogue_number] => PA 07 24670
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[chemical_name] =>
[weight] => 447.89
[form] => C22H23ClFN3O4
[cas] => 1608115-59-8
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3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one
Catalogue No.:PA 07 24670
Molecular Formula : C22H23ClFN3O4
Molecular Weight : 447.89
stdClass Object
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[pname] => 7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 24680
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[chemical_name] =>
[weight] => 485.77
[form] => C21H20Cl3FN4O2
[cas] => 2921918-23-0
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7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24680
Molecular Formula : C21H20Cl3FN4O2
Molecular Weight : 485.77
stdClass Object
(
[pname] => 4-chloro-7-methoxyquinazolin-6-yl acetate
[catalogue_number] => PA 07 0241000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 252.65
[form] => C11H9ClN2O3
[cas] => 230955-75-6
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4-chloro-7-methoxyquinazolin-6-yl acetate
Catalogue No.:PA 07 0241000
Molecular Formula : C11H9ClN2O3
Molecular Weight : 252.65
stdClass Object
(
[pname] => Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate
[catalogue_number] => PA 07 0241001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 324.38
[form] => C16H24N2O5
[cas] => 214472-41-0
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Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate
Catalogue No.:PA 07 0241001
Molecular Formula : C16H24N2O5
Molecular Weight : 324.38
stdClass Object
(
[pname] => Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate
[catalogue_number] => PA 07 0241002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 354.36
[form] => C16H22N2O7
[cas] => 214472-37-4
[pslug] => 214472-37-4-methyl-4-methoxy-5-3-morpholinopropoxy-2-nitrobenzoate-pa070241002
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Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate
Catalogue No.:PA 07 0241002
Molecular Formula : C16H22N2O7
Molecular Weight : 354.36
stdClass Object
(
[pname] => Gefitinib Nitroso Impurity
[catalogue_number] => PA 07 0241003
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 475.91
[form] => C22H23ClFN5O4
[cas] => NA
[pslug] => gefitinib-nitroso-impurity-pa070241003
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Gefitinib Nitroso Impurity
Catalogue No.:PA 07 0241003
Molecular Formula : C22H23ClFN5O4
Molecular Weight : 475.91