ibrutinib

Ibrutinib is used to treat chronic lymphocytic leukemia Waldenström's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease. It is a small molecule drug. Reference standards of Ibrutinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

Catalogue No.:PA 09 27510
CAS :
NA
Molecular Formula : C₄₇H₄₆N₁₂O₃
Molecular Weight : 826.95

Enquire

Details

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate

Catalogue No.:PA 09 27520
CAS :
NA
Molecular Formula : C₂₈H₂₈N₆O₄
Molecular Weight : 512.56

Enquire

Details

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one

Catalogue No.:PA 09 27530
CAS :
2031255-23-7
Molecular Formula : C₅₀H₄₈N₁₂O₄
Molecular Weight : 880.99

Enquire

Details

4-Aminopyrazolo[3,4-d]pyrimidine

Catalogue No.:PAI 09 007080
CAS :
2380-63-4
Molecular Formula : C₅H₅N₅
Molecular Weight : 135.13

Enquire

Details

Ibrutinib-biotin

Catalogue No.:PA 09 0271001
CAS :
1599432-18-4
Molecular Formula : C₅₆H₈₀N₁₂O₉S
Molecular Weight : 1097.39

Enquire

Details

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethan-1-one

Catalogue No.:PA 09 0271002
CAS :
NA
Molecular Formula : C₂₄H₂₄N₆O₂
Molecular Weight : 428.5

Enquire

Details

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one

Catalogue No.:PA 09 0271003
CAS :
1288338-96-4
Molecular Formula : C₂₅H₂₅ClN₆O₂
Molecular Weight : 476.97

Enquire

Details

(R)-N-(3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,1,1-triphenyl-l5-phosphanimine

Catalogue No.:PA 09 0271004
CAS :
NA
Molecular Formula : C₄₀H₃₅N₆OP
Molecular Weight : 646.73

Enquire

Details

(R)-1-(3-(3-(4-Phenoxyphenyl)-4-((triphenyl-l5-phosphanylidene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

Catalogue No.:PA 09 0271005
CAS :
NA
Molecular Formula : C₄₃H₃₇N₆O₂P
Molecular Weight : 700.78

Enquire

Details

1-((S)-3-(2-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-2,4-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

Catalogue No.:PA 09 0271006
CAS :
NA
Molecular Formula : C₅₀H₄₈N₁₂O₄
Molecular Weight : 881.01

Enquire

Details

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Dihydrochloride

Catalogue No.:PA 09 0271007
CAS :
1701403-10-2
Molecular Formula : C₂₂H₂₄Cl₂N₆O
Molecular Weight : 459.38

Enquire

Details

Ibrutinib N-Oxide impurity

Catalogue No.:PA 09 0271008
CAS :
NA
Molecular Formula : C₂₅H₂₄N₆O₃
Molecular Weight : 456.5

Enquire

Details

(R)-N-Desacryloyl N-Propionyl Ibrutinib

Catalogue No.:PA 09 0271009
CAS :
1839099-22-7
Molecular Formula : C₂₅H₂₆N₆O₂
Molecular Weight : 442.52

Enquire

Details

1-((R)-3-(5-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

Catalogue No.:PA 09 0271012
CAS :
2417548-76-4
Molecular Formula : C₅₀H₄₈N₁₂O₄
Molecular Weight : 881.01

Enquire

Details

1-((R)-3-(4-Amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one

Catalogue No.:PA STI 088988
CAS :
2068022-09-1
Molecular Formula : C₂₅H₂₁D₅N₆O₄
Molecular Weight : 479.55

Enquire

Details

1-Methyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Catalogue No.:PA 09 0271010
CAS :
2213398-75-3
Molecular Formula : C₁₈H₁₅N₅O
Molecular Weight : 317.35

Enquire

Details

1,1'-(((Oxybis(4,1-phenylene))bis(4-amino-1H-pyrazolo[3,4-d]pyrimidine-3,1-diyl))bis(piperidine-3,1-diyl))bis(prop-2-en-1-one)

Catalogue No.:PA 09 0271011
CAS :
NA
Molecular Formula : C₃₈H₃₈N₁₂O₃
Molecular Weight : 710.8

Enquire

Details

ibrutinib

1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

NA

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate

NA

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one

2031255-23-7

4-Aminopyrazolo[3,4-d]pyrimidine

2380-63-4

Ibrutinib-biotin

1599432-18-4

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethan-1-one

NA

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one

1288338-96-4

(R)-N-(3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,1,1-triphenyl-l5-phosphanimine

NA

(R)-1-(3-(3-(4-Phenoxyphenyl)-4-((triphenyl-l5-phosphanylidene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

NA

1-((S)-3-(2-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-2,4-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

NA

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Dihydrochloride

1701403-10-2

Ibrutinib N-Oxide impurity

NA

(R)-N-Desacryloyl N-Propionyl Ibrutinib

1839099-22-7

1-((R)-3-(5-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

2417548-76-4

1-((R)-3-(4-Amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one

2068022-09-1

1-Methyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

2213398-75-3

1,1'-(((Oxybis(4,1-phenylene))bis(4-amino-1H-pyrazolo[3,4-d]pyrimidine-3,1-diyl))bis(piperidine-3,1-diyl))bis(prop-2-en-1-one)

NA

Calculators

Periodic Table

Ask a Scientist

General Help

ibrutinib

1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

NA

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate

NA

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one

2031255-23-7

4-Aminopyrazolo[3,4-d]pyrimidine

2380-63-4

Ibrutinib-biotin

1599432-18-4

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethan-1-one

NA

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one

1288338-96-4

(R)-N-(3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,1,1-triphenyl-l5-phosphanimine

NA

(R)-1-(3-(3-(4-Phenoxyphenyl)-4-((triphenyl-l5-phosphanylidene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

NA

1-((S)-3-(2-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-2,4-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

NA

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Dihydrochloride

1701403-10-2

Ibrutinib N-Oxide impurity

NA

(R)-N-Desacryloyl N-Propionyl Ibrutinib

1839099-22-7

1-((R)-3-(5-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

2417548-76-4

1-((R)-3-(4-Amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one

2068022-09-1

1-Methyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

2213398-75-3

1,1'-(((Oxybis(4,1-phenylene))bis(4-amino-1H-pyrazolo[3,4-d]pyrimidine-3,1-diyl))bis(piperidine-3,1-diyl))bis(prop-2-en-1-one)

NA

Do you want a quotation or have a question about '' ? We normally respond within 2 hours.

Do you want a quotation or have a question about '' ? We normally respond within 2 hours.

Calculators

Periodic Table

Ask a Scientist

General Help