ketoconazole

Impurities - Ketoconazole is used for fungal skin infections such as tinea, cutaneous candidiasis, pityriasis versicolor, dandruff, and seborrhoeic dermatitis. It is sold under the brand name Nizoral. Reference standards of Ketoconazole API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ketoconazole - Impurity A
    [catalogue_number] => PA 11 03010
    [category_ids] => ,71,81,75,78,70,82,
    [chemical_name] => 
    [weight] => 529.42
    [form] => C26H26Cl2N4O4
    [cas] => 254912-63-5
    [pslug] => 254912-63-5-ketoconazole-impurity-a-pa1103010
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PA 11 03010
PA 11 03010

Ketoconazole - Impurity A


  • Catalogue No.:PA 11 03010

  • CAS :

    254912-63-5

  • Molecular Formula : C26H26Cl2N4O4

  • Molecular Weight : 529.42

stdClass Object
(
    [pname] => Ketoconazole - Impurity B
    [catalogue_number] => PA 11 03020
    [category_ids] => ,71,81,75,78,70,82,
    [chemical_name] => 
    [weight] => 749.68
    [form] => C38H42Cl2N6O6
    [cas] => 1346598-39-7
    [pslug] => 1346598-39-7-ketoconazole-impurity-b-pa1103020
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PA 11 03020
PA 11 03020

Ketoconazole - Impurity B


  • Catalogue No.:PA 11 03020

  • CAS :

    1346598-39-7

  • Molecular Formula : C38H42Cl2N6O6

  • Molecular Weight : 749.68

stdClass Object
(
    [pname] => (2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methanol
    [catalogue_number] => PA 11 0031000
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 329.18
    [form] => C14H14Cl2N2O3
    [cas] => 84682-23-5
    [pslug] => 84682-23-5-2-1h-imidazol-1-yl-methyl-2-2-4-dichlorophenyl-1-3-dioxolan-4-yl-methanol-pa110031000
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PA 11 0031000
PA 11 0031000

(2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methanol


  • Catalogue No.:PA 11 0031000

  • CAS :

    84682-23-5

  • Molecular Formula : C14H14Cl2N2O3

  • Molecular Weight : 329.18

stdClass Object
(
    [pname] => (2R,4R)-trans-Ketoconazole
    [catalogue_number] => PA 11 0031001
    [category_ids] => ,123,81,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 531.43
    [form] => C26H28Cl2N4O4
    [cas] => 142128-58-3
    [pslug] => 142128-58-3-2r-4r-trans-ketoconazole-pa110031001
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PA 11 0031001
PA 11 0031001

(2R,4R)-trans-Ketoconazole


  • Catalogue No.:PA 11 0031001

  • CAS :

    142128-58-3

  • Molecular Formula : C26H28Cl2N4O4

  • Molecular Weight : 531.43

stdClass Object
(
    [pname] => Ketoconazole N-Oxide
    [catalogue_number] => PA 11 0031002
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 547.43
    [form] => C26H28Cl2N4O5
    [cas] => 254912-65-7
    [pslug] => 254912-65-7-ketoconazole n-oxide-pa110031002
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PA 11 0031002
PA 11 0031002

Ketoconazole N-Oxide


  • Catalogue No.:PA 11 0031002

  • CAS :

    254912-65-7

  • Molecular Formula : C26H28Cl2N4O5

  • Molecular Weight : 547.43

stdClass Object
(
    [pname] => cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
    [catalogue_number] => PA 11 0031003
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 329.18
    [form] => C14H14Cl2N2O3
    [cas] => 61397-58-8
    [pslug] => 61397-58-8-cis-2-2-4-dichlorophenyl-2-1h-imidazol-1-ylmethyl-1-3-dioxolane-4-methanol-pa110031003
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PA 11 0031003
PA 11 0031003

cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol


  • Catalogue No.:PA 11 0031003

  • CAS :

    61397-58-8

  • Molecular Formula : C14H14Cl2N2O3

  • Molecular Weight : 329.18

stdClass Object
(
    [pname] => 1-(4-(4-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one
    [catalogue_number] => PA 11 0031004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 496.99
    [form] => C26H29ClN4O4
    [cas] => 1334423-12-9
    [pslug] => 1334423-12-9-1-4-4-2r-4s-2-1h-imidazol-1-yl-methyl-2-2-chlorophenyl-1-3-dioxolan-4-yl-methoxy-phenyl-piperazin-1-yl-ethan-1-one-pa110031004
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PA 11 0031004
PA 11 0031004

1-(4-(4-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one


  • Catalogue No.:PA 11 0031004

  • CAS :

    1334423-12-9

  • Molecular Formula : C26H29ClN4O4

  • Molecular Weight : 496.99

stdClass Object
(
    [pname] => 1-(4-(4-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(4-chlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one
    [catalogue_number] => PA 11 0031005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 496.99
    [form] => C26H29ClN4O4
    [cas] => 91458-32-1
    [pslug] => 91458-32-1-1-4-4-2r-4s-2-1h-imidazol-1-yl-methyl-2-4-chlorophenyl-1-3-dioxolan-4-yl-methoxy-phenyl-piperazin-1-yl-ethan-1-one-pa110031005
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PA 11 0031005
PA 11 0031005

1-(4-(4-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(4-chlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one


  • Catalogue No.:PA 11 0031005

  • CAS :

    91458-32-1

  • Molecular Formula : C26H29ClN4O4

  • Molecular Weight : 496.99

stdClass Object
(
    [pname] => 4-Acetyl-1-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazole-1-carbonyl)-1,3-dioxolan-4-yl)methoxy)-3,6-dioxocyclohexa-1,4-dien-1-yl)piperazine-2,6-dione
    [catalogue_number] => PA 11 0031006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 603.37
    [form] => C26H20Cl2N4O9
    [cas] => NA
    [pslug] => 4-acetyl-1-4-2-2-4-dichlorophenyl-2-1h-imidazole-1-carbonyl-1-3-dioxolan-4-yl-methoxy-3-6-dioxocyclohexa-1-4-dien-1-yl-piperazine-2-6-dione-pa110031006
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PA 11 0031006
PA 11 0031006

4-Acetyl-1-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazole-1-carbonyl)-1,3-dioxolan-4-yl)methoxy)-3,6-dioxocyclohexa-1,4-dien-1-yl)piperazine-2,6-dione


  • Catalogue No.:PA 11 0031006

  • CAS :

    NA

  • Molecular Formula : C26H20Cl2N4O9

  • Molecular Weight : 603.37

stdClass Object
(
    [pname] => 2-(((2S,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-5-(4-acetylpyrazin-1(4H)-yl)cyclohexa-2,5-diene-1,4-dione
    [catalogue_number] => PA 11 0031007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 557.38
    [form] => C26H22Cl2N4O6
    [cas] => NA
    [pslug] => 2-2s-4s-2-1h-imidazol-1-yl-methyl-2-2-4-dichlorophenyl-1-3-dioxolan-4-yl-methoxy-5-4-acetylpyrazin-1-4h-yl-cyclohexa-2-5-diene-1-4-dione-pa110031007
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PA 11 0031007
PA 11 0031007

2-(((2S,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-5-(4-acetylpyrazin-1(4H)-yl)cyclohexa-2,5-diene-1,4-dione


  • Catalogue No.:PA 11 0031007

  • CAS :

    NA

  • Molecular Formula : C26H22Cl2N4O6

  • Molecular Weight : 557.38

stdClass Object
(
    [pname] => N-((Z)-2-((4-(((2S,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)amino)vinyl)acetamide
    [catalogue_number] => PA 11 0031008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 503.38
    [form] => C24H24Cl2N4O4
    [cas] => NA
    [pslug] => n-z-2-4-2s-4s-2-1h-imidazol-1-yl-methyl-2-2-4-dichlorophenyl-1-3-dioxolan-4-yl-methoxy-phenyl-amino-vinyl-acetamide-pa110031008
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PA 11 0031008
PA 11 0031008

N-((Z)-2-((4-(((2S,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)amino)vinyl)acetamide


  • Catalogue No.:PA 11 0031008

  • CAS :

    NA

  • Molecular Formula : C24H24Cl2N4O4

  • Molecular Weight : 503.38

stdClass Object
(
    [pname] => 1-(4-(((2S,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetyl-1,2,3,4-tetrahydropyrazine 1-oxide
    [catalogue_number] => PA 11 0031009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 545.42
    [form] => C26H26Cl2N4O5
    [cas] => NA
    [pslug] => 1-4-2s-4s-2-1h-imidazol-1-yl-methyl-2-2-4-dichlorophenyl-1-3-dioxolan-4-yl-methoxy-phenyl-4-acetyl-1-2-3-4-tetrahydropyrazine-1-oxide-pa110031009
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PA 11 0031009
PA 11 0031009

1-(4-(((2S,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetyl-1,2,3,4-tetrahydropyrazine 1-oxide


  • Catalogue No.:PA 11 0031009

  • CAS :

    NA

  • Molecular Formula : C26H26Cl2N4O5

  • Molecular Weight : 545.42

stdClass Object
(
    [pname] => Tert-butyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate
    [catalogue_number] => PA 11 0031010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 278.35
    [form] => C15H22N2O3
    [cas] => 158985-25-2
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PA 11 0031010
PA 11 0031010

Tert-butyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate


  • Catalogue No.:PA 11 0031010

  • CAS :

    158985-25-2

  • Molecular Formula : C15H22N2O3

  • Molecular Weight : 278.35

stdClass Object
(
    [pname] => 4-(Piperazin-1-yl)phenol Hydrochloride
    [catalogue_number] => PA 11 0031011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 214.69
    [form] => C10H15ClN2O
    [cas] => 1175036-51-7
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PA 11 0031011
PA 11 0031011

4-(Piperazin-1-yl)phenol Hydrochloride


  • Catalogue No.:PA 11 0031011

  • CAS :

    1175036-51-7

  • Molecular Formula : C10H15ClN2O

  • Molecular Weight : 214.69

stdClass Object
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    [pname] => 3-Butenyl Tosylate
    [catalogue_number] => PA 11 0031012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 226.29
    [form] => C11H14O3S
    [cas] => 778-29-0
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PA 11 0031012
PA 11 0031012

3-Butenyl Tosylate


  • Catalogue No.:PA 11 0031012

  • CAS :

    778-29-0

  • Molecular Formula : C11H14O3S

  • Molecular Weight : 226.29

stdClass Object
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    [pname] => Ketoconazole Hydroxy Impurity
    [catalogue_number] => PA 11 0031013
    [category_ids] => ,76,75,70,78,82,
    [chemical_name] => 
    [weight] => 547.43
    [form] => C26H28Cl2N4O5
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PA 11 0031013
PA 11 0031013

Ketoconazole Hydroxy Impurity


  • Catalogue No.:PA 11 0031013

  • CAS :

    NA

  • Molecular Formula : C26H28Cl2N4O5

  • Molecular Weight : 547.43

stdClass Object
(
    [pname] => Trans-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate
    [catalogue_number] => PA 11 03610
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    [chemical_name] => 
    [weight] => 446.12
    [form] => C18H15BrCl2O4
    [cas] => 61397-57-7
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PA 11 03610
PA 11 03610

Trans-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate


  • Catalogue No.:PA 11 03610

  • CAS :

    61397-57-7

  • Molecular Formula : C18H15BrCl2O4

  • Molecular Weight : 446.12

stdClass Object
(
    [pname] => rel-N-[2-[[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]amino]ethyl]acetamide
    [catalogue_number] => PA 11 0031014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 505.4
    [form] => C24H26Cl2N4O4
    [cas] => 1253852-50-4
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PA 11 0031014
PA 11 0031014

rel-N-[2-[[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]amino]ethyl]acetamide


  • Catalogue No.:PA 11 0031014

  • CAS :

    1253852-50-4

  • Molecular Formula : C24H26Cl2N4O4

  • Molecular Weight : 505.4

stdClass Object
(
    [pname] => ((2R,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methanol
    [catalogue_number] => PA 11 0031019
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 329.18
    [form] => C14H14Cl2N2O3
    [cas] => 2760728-23-0
    [pslug] => 2760728-23-0-2r-4r-2-1h-imidazol-1-yl-methyl-2-2-4-dichlorophenyl-1-3-dioxolan-4-yl-methanol-pa110031019
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PA 11 0031019
PA 11 0031019

((2R,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methanol


  • Catalogue No.:PA 11 0031019

  • CAS :

    2760728-23-0

  • Molecular Formula : C14H14Cl2N2O3

  • Molecular Weight : 329.18

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