levocetirizine
A non-sedative antihistamine that belongs to third generation, Levocetirizine is active enantiomer of cetirizine. It is an inverse agonist that decreases activity at histamine H1 receptors. It is more effective than cetirizine with fewer side effects. Reference standards of Levocetirizine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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De(carboxymethoxy) Cetirizine Acetic Acid
Catalogue No.:PA 12 11020
Molecular Formula : C19H21ClN2O2
Molecular Weight : 344.84
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Cetirizine 2-Chloro Impurity Dihydrochloride
Catalogue No.:PA 12 11030
Molecular Formula : C21H27Cl3N2O3
Molecular Weight : 461.81
stdClass Object
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Levocetirizine Dihydrochloride - Impurity F
Catalogue No.:PA 12 11031
Molecular Formula : C21H25ClN2O3
Molecular Weight : 388.89
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1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine Dihydrochloride
Catalogue No.:PA 12 11040
Molecular Formula : C30H30Cl4N2
Molecular Weight : 560.38
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1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine
Catalogue No.:PA 12 11041
Molecular Formula : C30H28Cl2N2
Molecular Weight : 487.46
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Hydroxyzine Acetic Acid Dihydrochloride
Catalogue No.:PA 12 11050
Molecular Formula : C23H31Cl3N2O4
Molecular Weight : 505.86
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Catalogue No.:PA 12 11051
Molecular Formula : C23H29ClN2O4
Molecular Weight : 432.94
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Deschloro Cetirizine Dihydrochloride
Catalogue No.:PA 12 11060
Molecular Formula : C21H28Cl2N2O3
Molecular Weight : 427.36
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Levocetirizine Dihydrochloride - Impurity H (Hydrochloride Salt)
Catalogue No.:PA 12 11071
Molecular Formula : C19H24Cl2N2O
Molecular Weight : 367.31
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Levocetirizine Dihydrochloride - Impurity F (Hydrochloride Salt)
Catalogue No.:PA 12 0110060
Molecular Formula : C21H26Cl2N2O3
Molecular Weight : 425.35
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Levocetirizine Dihydrochloride - Impurity H
Catalogue No.:PA 12 0110080
Molecular Formula : C19H23ClN2O
Molecular Weight : 330.86
stdClass Object
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[pname] => Levocetirizine N-Oxide
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Catalogue No.:PA 12 11520
Molecular Formula : C21H25ClN2O4
Molecular Weight : 404.89
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Levocetirizine Dihydrochloride - Impurity A (Dihydrochloride Salt)
Catalogue No.:PA 12 11570
Molecular Formula : C21H27Cl3N2O3
Molecular Weight : 461.81
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[catalogue_number] => PA 12 11580
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[weight] => 217.69
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(R)-(4-Chlorophenyl)(phenyl)methanamine
Catalogue No.:PA 12 11580
Molecular Formula : C13H12ClN
Molecular Weight : 217.69
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[weight] => 478.03
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Levocetirizine N-benzyl Amide
Catalogue No.:PA 12 11590
Molecular Formula : C28H32ClN3O2
Molecular Weight : 478.03
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Levocetirizine Dihydrochloride - Impurity J
Catalogue No.:PA 12 11600
Molecular Formula : C21H26ClN3O2
Molecular Weight : 387.91
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[weight] => 254.16
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4-Chlorobenzhydrylamine Hydrochloride
Catalogue No.:PA 12 11610
Molecular Formula : C13H13Cl2N
Molecular Weight : 254.16
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Levocetirizine Dihydrochloride - Impurity C
Catalogue No.:PA 12 11620
Molecular Formula : C23H23ClN2O2S
Molecular Weight : 426.96
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[weight] => 388.89
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Catalogue No.:PA 12 0111000
Molecular Formula : C21H25ClN2O3
Molecular Weight : 388.89
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(R)-De(carboxymethoxy) Cetirizine Acetic Acid
Catalogue No.:PA 12 0111001
Molecular Formula : C19H21ClN2O2
Molecular Weight : 344.84
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Catalogue No.:PA 12 0111002
Molecular Formula : C16H18N2O
Molecular Weight : 254.33
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(R)-2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid hydrochloride
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2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetic Acid
Catalogue No.:PA 12 0111004
Molecular Formula : C21H23ClN2O4
Molecular Weight : 402.88
stdClass Object
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[pname] => (S)-2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic Acid
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[weight] => 344.84
[form] => C19H21ClN2O2
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(S)-2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic Acid
Catalogue No.:PA 12 0111005
Molecular Formula : C19H21ClN2O2
Molecular Weight : 344.84
stdClass Object
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[catalogue_number] => PA 12 0110010
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[weight] => 388.89
[form] => C21H25ClN2O3
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Levocetirizine Dihydrochloride - Impurity A
Catalogue No.:PA 12 0110010
Molecular Formula : C21H25ClN2O3
Molecular Weight : 388.89
stdClass Object
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[pname] => Levocetirizine Dihydrochloride - Impurity D
[catalogue_number] => PA 12 0110040
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[weight] => 344.84
[form] => C19H21ClN2O2
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Levocetirizine Dihydrochloride - Impurity D
Catalogue No.:PA 12 0110040
Molecular Formula : C19H21ClN2O2
Molecular Weight : 344.84
stdClass Object
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[pname] => Levocetirizine Dihydrochloride - Impurity E
[catalogue_number] => PA 12 0110050
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[chemical_name] =>
[weight] => 490.98
[form] => C25H31ClN2O6
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Levocetirizine Dihydrochloride - Impurity E
Catalogue No.:PA 12 0110050
Molecular Formula : C25H31ClN2O6
Molecular Weight : 490.98
stdClass Object
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[pname] => Levocetirizine Dihydrochloride - Impurity I
[catalogue_number] => PA 12 0110090
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[chemical_name] =>
[weight] => 286.8
[form] => C17H19ClN2
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Levocetirizine Dihydrochloride - Impurity I
stdClass Object
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[pname] => (R)-(4-Chlorophenyl)(phenyl)methanamine (2R,3R)-2,3-dihydroxysuccinate
[catalogue_number] => PA 12 0111011
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[chemical_name] =>
[weight] => 367.78
[form] => C17H18ClNO6
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(R)-(4-Chlorophenyl)(phenyl)methanamine (2R,3R)-2,3-dihydroxysuccinate
Catalogue No.:PA 12 0111011
Molecular Formula : C17H18ClNO6
Molecular Weight : 367.78
stdClass Object
(
[pname] => (R)-1-((4-Chlorophenyl)(phenyl)methyl)-4-tosylpiperazine
[catalogue_number] => PA 12 0111012
[category_ids] => ,79,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 440.99
[form] => C24H25ClN2O2S
[cas] => 942283-97-8
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(R)-1-((4-Chlorophenyl)(phenyl)methyl)-4-tosylpiperazine
Catalogue No.:PA 12 0111012
Molecular Formula : C24H25ClN2O2S
Molecular Weight : 440.99