Nalfurafine
Nalfurafine (INN, USAN) (brand name Remitch, former developmental code names TRK-820, AC-820, MT-9938) is an antipruritic (anti-itch drug) that is marketed in Japan for the treatment of uremic pruritus in individuals with chronic kidney disease undergoing hemodialysis. Reference standards of Nalfurafine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Nalfurafine
[catalogue_number] => PA 14 1230000
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[chemical_name] =>
[weight] => 476.57
[form] => C28H32N2O5
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Catalogue No.:PA 14 1230000
Molecular Formula : C28H32N2O5
Molecular Weight : 476.57
stdClass Object
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[pname] => Nalfurafine hydrochloride
[catalogue_number] => PA 14 1231000
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[chemical_name] =>
[weight] => 513.03
[form] => C28H33ClN2O5
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Nalfurafine hydrochloride
Catalogue No.:PA 14 1231000
Molecular Formula : C28H33ClN2O5
Molecular Weight : 513.03
stdClass Object
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[pname] => 10α-Hydroxy-nalfurafine
[catalogue_number] => PA 14 1231001
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[chemical_name] =>
[weight] => 492.57
[form] => C28H32N2O6
[cas] => 1054312-75-2
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Catalogue No.:PA 14 1231001
Molecular Formula : C28H32N2O6
Molecular Weight : 492.57
stdClass Object
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[pname] => 2Z-Nalfurafine
[catalogue_number] => PA 14 1231002
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[weight] => 476.57
[form] => C28H32N2O5
[cas] => 163712-68-3
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Catalogue No.:PA 14 1231002
Molecular Formula : C28H32N2O5
Molecular Weight : 476.57
stdClass Object
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[pname] => Descyclopropylmethyl Nalfurafine
[catalogue_number] => PA 14 1231003
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[chemical_name] =>
[weight] => 422.48
[form] => C24H26N2O5
[cas] => 163713-06-2
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Descyclopropylmethyl Nalfurafine
Catalogue No.:PA 14 1231003
Molecular Formula : C24H26N2O5
Molecular Weight : 422.48
stdClass Object
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[pname] => (4R,4aS,7S,7aR,12bS)-7-(Benzyl(methyl)amino)-3-(cyclopropylmethyl)-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
[catalogue_number] => PA 14 1231004
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[chemical_name] =>
[weight] => 446.59
[form] => C28H34N2O3
[cas] => NA
[pslug] => 4r-4as-7s-7ar-12bs-7-benzyl-methyl-amino-3-cyclopropylmethyl-1-2-3-4-5-6-7-7a-octahydro-4ah-4-12-methanobenzofuro-3-2-e-isoquinoline-4a-9-diol-pa141231004
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(4R,4aS,7S,7aR,12bS)-7-(Benzyl(methyl)amino)-3-(cyclopropylmethyl)-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Catalogue No.:PA 14 1231004
Molecular Formula : C28H34N2O3
Molecular Weight : 446.59
stdClass Object
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[pname] => (E)-N-((4R,4aS,7R,7aR,12bS,13S)-3-(Cyclopropylmethyl)-4a,9,13-trihydroxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)-3-(furan-2-yl)-N-methylacrylamide
[catalogue_number] => PA 14 1231005
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[weight] => 492.57
[form] => C28H32N2O6
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(E)-N-((4R,4aS,7R,7aR,12bS,13S)-3-(Cyclopropylmethyl)-4a,9,13-trihydroxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)-3-(furan-2-yl)-N-methylacrylamide
Catalogue No.:PA 14 1231005
Molecular Formula : C28H32N2O6
Molecular Weight : 492.57