naproxen
Impurities
- A nonselective COX inhibitor, Naproxen is a Non-steroidal anti-inflammatory drug that belongs to class of 2-arylpropionic acid. It is used for the treatment of fever, pain and inflammation. Reference standards of Naproxen API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Naproxen - Impurity A
[catalogue_number] => PA 14 13010
[category_ids] => ,69,76,75,78,70,82,
[chemical_name] =>
[weight] => 216.23
[form] => C13H12O3
[cas] => 52079-10-4
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Catalogue No.:PA 14 13010
Molecular Formula : C13H12O3
Molecular Weight : 216.23
stdClass Object
(
[pname] => Naproxen - Impurity B
[catalogue_number] => PA 14 13020
[category_ids] => ,82,80,78,75,70,69,
[chemical_name] =>
[weight] => 264.70
[form] => C14H13ClO3
[cas] => 89617-86-7
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Catalogue No.:PA 14 13020
Molecular Formula : C14H13ClO3
Molecular Weight : 264.70
stdClass Object
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[pname] => Naproxen - Impurity C
[catalogue_number] => PA 14 13030
[category_ids] => ,82,80,78,75,70,69,
[chemical_name] =>
[weight] => 309.16
[form] => C14H13BrO3
[cas] => 84236-26-0
[pslug] => 84236-26-0-naproxen-impurity-c-pa1413030
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Catalogue No.:PA 14 13030
Molecular Formula : C14H13BrO3
Molecular Weight : 309.16
stdClass Object
(
[pname] => Naproxen - Impurity D
[catalogue_number] => PA 14 13040
[category_ids] => ,80,69,75,78,70,82,
[chemical_name] =>
[weight] => 356.16
[form] => C14H13IO3
[cas] => 116883-62-6
[pslug] => 116883-62-6-naproxen-impurity-d-pa1413040
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Catalogue No.:PA 14 13040
Molecular Formula : C14H13IO3
Molecular Weight : 356.16
stdClass Object
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[pname] => Naproxen - Impurity E
[catalogue_number] => PA 14 13050
[category_ids] => ,82,80,78,75,70,69,
[chemical_name] =>
[weight] => 244.29
[form] => C15H16O3
[cas] => 26159-35-3
[pslug] => 26159-35-3-naproxen-impurity-e-pa1413050
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Catalogue No.:PA 14 13050
Molecular Formula : C15H16O3
Molecular Weight : 244.29
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(
[pname] => Naproxen - Impurity I
[catalogue_number] => PA 14 13090
[category_ids] => ,80,81,76,75,
[chemical_name] =>
[weight] => 216.23
[form] => C13H12O3
[cas] => 23981-47-7
[pslug] => 23981-47-7-naproxen-impurity-i-pa1413090
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Catalogue No.:PA 14 13090
Molecular Formula : C13H12O3
Molecular Weight : 216.23
stdClass Object
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[pname] => Naproxen - Impurity J
[catalogue_number] => PA 14 13100
[category_ids] => ,80,76,75,78,70,82,
[chemical_name] =>
[weight] => 186.25
[form] => C13H14O
[cas] => 21388-17-0
[pslug] => 21388-17-0-naproxen-impurity-j-pa1413100
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Catalogue No.:PA 14 13100
Molecular Formula : C13H14O
Molecular Weight : 186.25
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[pname] => Naproxen - Impurity K
[catalogue_number] => PA 14 13110
[category_ids] => ,70,75,78,80,82,
[chemical_name] =>
[weight] => 202.25
[form] => C13H14O2
[cas] => 77301-42-9
[pslug] => 77301-42-9-naproxen-impurity-k-pa1413110
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Catalogue No.:PA 14 13110
Molecular Formula : C13H14O2
Molecular Weight : 202.25
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[pname] => Naproxen - Impurity L
[catalogue_number] => PA 14 13120
[category_ids] => ,70,75,78,82,80,
[chemical_name] =>
[weight] => 200.24
[form] => C13H12O2
[cas] => 3900-45-6
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Catalogue No.:PA 14 13120
Molecular Formula : C13H12O2
Molecular Weight : 200.24
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[pname] => Naproxen - Impurity M
[catalogue_number] => PA 14 13130
[category_ids] => ,80,75,78,70,82,
[chemical_name] =>
[weight] => 158.20
[form] => C11H10O
[cas] => 93-04-9
[pslug] => 93-04-9-naproxen-impurity-m-pa1413130
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Catalogue No.:PA 14 13130
Molecular Formula : C11H10O
Molecular Weight : 158.20
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[pname] => Naproxen - Impurity N
[catalogue_number] => PA 14 13140
[category_ids] => ,80,75,78,70,82,
[chemical_name] =>
[weight] => 237.09
[form] => C11H9BrO
[cas] => 5111-65-9
[pslug] => 5111-65-9-naproxen-impurity-n-pa1413140
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Catalogue No.:PA 14 13140
Molecular Formula : C11H9BrO
Molecular Weight : 237.09
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[pname] => Naproxen - Impurity O
[catalogue_number] => PA 14 13150
[category_ids] => ,80,75,78,70,82,
[chemical_name] =>
[weight] => 202.21
[form] => C12H10O3
[cas] => 2471-70-7
[pslug] => 2471-70-7-naproxen-impurity-o-pa1413150
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Catalogue No.:PA 14 13150
Molecular Formula : C12H10O3
Molecular Weight : 202.21
stdClass Object
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[catalogue_number] => PA 14 13520
[category_ids] => ,76,75,82,78,70,80,
[chemical_name] =>
[weight] => 274.31
[form] => C16H18O4
[cas] => 2749415-34-5
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Isopropyl 2-hydroxy-2-(6-methoxynaphthalen-2-yl)acetate
Catalogue No.:PA 14 13520
Molecular Formula : C16H18O4
Molecular Weight : 274.31
stdClass Object
(
[pname] => rac-5-Bromo Naproxen
[catalogue_number] => PA 14 13530
[category_ids] => ,80,69,75,78,70,82,
[chemical_name] =>
[weight] => 309.16
[form] => C14H13BrO3
[cas] => 27655-95-4
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Catalogue No.:PA 14 13530
Molecular Formula : C14H13BrO3
Molecular Weight : 309.16
stdClass Object
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[pname] => (R)-5-Bromo Naproxen
[catalogue_number] => PA 14 13540
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[weight] => 309.16
[form] => C14H13BrO3
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Catalogue No.:PA 14 13540
Molecular Formula : C14H13BrO3
Molecular Weight : 309.16
stdClass Object
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[catalogue_number] => PA 14 13550
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[weight] => 264.7
[form] => C14H13ClO3
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[pname] => (R)-5-Chloro Naproxen
[catalogue_number] => PA 14 13560
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[weight] => 264.7
[form] => C14H13ClO3
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[pname] => 3-Isopropyl-1-methyl Naproxen
[catalogue_number] => PA 14 13590
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[chemical_name] =>
[weight] => 286.37
[form] => C18H22O3
[cas] => 1391054-24-2
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3-Isopropyl-1-methyl Naproxen
Catalogue No.:PA 14 13590
Molecular Formula : C18H22O3
Molecular Weight : 286.37
stdClass Object
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[pname] => 1-Methyl Naproxen
[catalogue_number] => PA 14 13600
[category_ids] => ,80,75,78,70,82,
[chemical_name] =>
[weight] => 244.29
[form] => C15H16O3
[cas] => 1391053-86-3
[pslug] => 1391053-86-3-1-methyl-naproxen-pa1413600
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Catalogue No.:PA 14 13600
Molecular Formula : C15H16O3
Molecular Weight : 244.29
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[pname] => rac-Naproxen
[catalogue_number] => PA 14 13670
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[weight] => 230.26
[form] => C14H14O3
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Catalogue No.:PA 14 13670
Molecular Formula : C14H14O3
Molecular Weight : 230.26
stdClass Object
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[pname] => 7-Naphthalenedisulfonic Acid
[catalogue_number] => PA 14 13680
[category_ids] => ,80,78,70,82,75,88,
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[weight] => 288.3
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7-Naphthalenedisulfonic Acid
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[weight] => 377.26
[form] => C10H5NNa2O8S2
[cas] => 525-05-3
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Disodium 3-hydroxy-4-nitrosonaphthalene-2,7-disulfonate
Catalogue No.:PA 14 13700
Molecular Formula : C10H5NNa2O8S2
Molecular Weight : 377.26
stdClass Object
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Catalogue No.:PA 14 13710
Molecular Formula : C13H12
Molecular Weight : 168.23
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[weight] => 200.23
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1-(2-Methoxynaphthalen-1-yl)ethanone
Catalogue No.:PA 14 13720
Molecular Formula : C13H12O2
Molecular Weight : 200.23
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1-(7-Methoxynaphthalen-1-yl)ethan-1-one
Catalogue No.:PA 14 13730
Molecular Formula : C13H12O2
Molecular Weight : 200.23
stdClass Object
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[catalogue_number] => PA STI 028530
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rac O-Desmethyl Naproxen-d3
Catalogue No.:PA STI 028530
Molecular Formula : C13H9D3O3
Molecular Weight : 219.25
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[cas] => 105937-62-0
[pslug] => 105937-62-0-a-hydroxy-6-methoxy-alpha-methyl-2-naphthaleneacetic-acid-methyl-ester-pa140131000
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A-Hydroxy-6-methoxy-α-methyl-2-naphthaleneacetic acid methyl ester
Catalogue No.:PA 14 0131000
Molecular Formula : C15H16O4
Molecular Weight : 260.29
stdClass Object
(
[pname] => α-(6-Methoxy-2-naphthyl)lactic Acid
[catalogue_number] => PA 14 0131001
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 246.26
[form] => C14H14O4
[cas] => 32721-11-2
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α-(6-Methoxy-2-naphthyl)lactic Acid
Catalogue No.:PA 14 0131001
Molecular Formula : C14H14O4
Molecular Weight : 246.26
stdClass Object
(
[pname] => Desmethylnaproxen
[catalogue_number] => PA 14 0131002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 216.24
[form] => C13H12O3
[cas] => 60756-73-2
[pslug] => 60756-73-2-desmethylnaproxen-pa140131002
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Catalogue No.:PA 14 0131002
Molecular Formula : C13H12O3
Molecular Weight : 216.24
stdClass Object
(
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[catalogue_number] => PAI 14 003511
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 186.21
[form] => C12H10O2
[cas] => 3453-33-6
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6-Methoxy-2-naphthaldehyde
Catalogue No.:PAI 14 003511
Molecular Formula : C12H10O2
Molecular Weight : 186.21
stdClass Object
(
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[catalogue_number] => PAI 14 003512
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 172.18
[form] => C11H8O2
[cas] => 78119-82-1
[pslug] => 78119-82-1-6-hydroxy-2-naphthaldehyde-pai14003512
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6-Hydroxy-2-naphthaldehyde
Catalogue No.:PAI 14 003512
Molecular Formula : C11H8O2
Molecular Weight : 172.18
stdClass Object
(
[pname] => 6-Methoxy-2-naphthonitrile
[catalogue_number] => PA 14 0131006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 183.21
[form] => C12H9NO
[cas] => 67886-70-8
[pslug] => 67886-70-8-6-methoxy-2-naphthonitrile-pa140131006
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6-Methoxy-2-naphthonitrile
Catalogue No.:PA 14 0131006
Molecular Formula : C12H9NO
Molecular Weight : 183.21
stdClass Object
(
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[catalogue_number] => PA 14 0131003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 209.29
[form] => C12H19NO2
[cas] => 156543-20-3
[pslug] => 156543-20-3-2-4-methoxybenzyl-amino-butan-1-ol-pa140131003
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2-((4-Methoxybenzyl)amino)butan-1-ol
Catalogue No.:PA 14 0131003
Molecular Formula : C12H19NO2
Molecular Weight : 209.29
stdClass Object
(
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[catalogue_number] => PA 14 0131004
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 356.16
[form] => C14H13IO3
[cas] => 116883-61-5
[pslug] => 116883-61-5-r-2-5-iodo-6-methoxynaphthalen-2-yl-propanoic-acid-pa140131004
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(R)-2-(5-Iodo-6-methoxynaphthalen-2-yl)propanoic acid
Catalogue No.:PA 14 0131004
Molecular Formula : C14H13IO3
Molecular Weight : 356.16
stdClass Object
(
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[catalogue_number] => PA 14 0131005
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 349.39
[form] => C21H19NO4
[cas] => 1000700-40-2
[pslug] => 1000700-40-2-4-carbamoylphenyl-2-6-methoxynaphthalen-2-yl-propanoate-pa140131005
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4-Carbamoylphenyl 2-(6-methoxynaphthalen-2-yl)propanoate
Catalogue No.:PA 14 0131005
Molecular Formula : C21H19NO4
Molecular Weight : 349.39
stdClass Object
(
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[catalogue_number] => PAI 14 003513
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 384.21
[form] => C16H17IO3
[cas] => NA
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Ethyl 2-(5-iodo-6-methoxynaphthalen-2-yl)propanoate
Catalogue No.:PAI 14 003513
Molecular Formula : C16H17IO3
Molecular Weight : 384.21
stdClass Object
(
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[catalogue_number] => PA 14 0131007
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 576.69
[form] => C34H40O8
[cas] => NA
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Naproxen 1,2-Propylene Glycol Esters (Mixture of Isomers)
Catalogue No.:PA 14 0131007
Molecular Formula : C34H40O8
Molecular Weight : 576.69
stdClass Object
(
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[catalogue_number] => PA 14 0131008
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 304.34
[form] => C17H20O5
[cas] => 38835-17-5
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2,3-Dihydroxypropyl 2-(6-methoxynaphthalen-2-yl)propanoate
Catalogue No.:PA 14 0131008
Molecular Formula : C17H20O5
Molecular Weight : 304.34
stdClass Object
(
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[catalogue_number] => PA 14 0131009
[category_ids] => ,75,76,78,70,82,
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[weight] => 228.25
[form] => C14H12O3
[cas] => 6328-74-1
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4-Phenoxyphenylacetic Acid
Catalogue No.:PA 14 0131009
Molecular Formula : C14H12O3
Molecular Weight : 228.25
stdClass Object
(
[pname] => (2S)-(2S-3R-4R-5R)-2,3,4,5,6-Pentahydroxyhexyl-2-(2-methoxy naphthalene-6-yl) propanoate
[catalogue_number] => PA 14 0131010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 394.42
[form] => C20H26O8
[cas] => 358369-77-4
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(2S)-(2S-3R-4R-5R)-2,3,4,5,6-Pentahydroxyhexyl-2-(2-methoxy naphthalene-6-yl) propanoate
Catalogue No.:PA 14 0131010
Molecular Formula : C20H26O8
Molecular Weight : 394.42
stdClass Object
(
[pname] => (R)-2-((2R,3R,4S)-3,4-Dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl (S)-2-(6-methoxynaphthalen-2-yl)propanoate
[catalogue_number] => PA 14 0131011
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 376.41
[form] => C20H24O7
[cas] => NA
[pslug] => r-2-2r-3r-4s-3-4-dihydroxytetrahydrofuran-2-yl-2-hydroxyethyl-s-2-6-methoxynaphthalen-2-yl-propanoate-pa140131011
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(R)-2-((2R,3R,4S)-3,4-Dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl (S)-2-(6-methoxynaphthalen-2-yl)propanoate
Catalogue No.:PA 14 0131011
Molecular Formula : C20H24O7
Molecular Weight : 376.41
stdClass Object
(
[pname] => Naproxen Lactic Acid Ester
[catalogue_number] => PA 14 0131014
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 302.33
[form] => C17H18O5
[cas] => 140225-89-4
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Naproxen Lactic Acid Ester
Catalogue No.:PA 14 0131014
Molecular Formula : C17H18O5
Molecular Weight : 302.33
stdClass Object
(
[pname] => Naproxen-d3
[catalogue_number] => PA STI 089175
[category_ids] => ,82,78,70,75,76,98,
[chemical_name] =>
[weight] => 233.28
[form] => C14H11D3O3
[cas] => 958293-79-3
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Catalogue No.:PA STI 089175
Molecular Formula : C14H11D3O3
Molecular Weight : 233.28
stdClass Object
(
[pname] => (R)-O-Desmethyl Naproxen
[catalogue_number] => PA 14 0131012
[category_ids] => ,75,76,78,70,82,
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[weight] => 216.24
[form] => C13H12O3
[cas] => 123050-98-6
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Catalogue No.:PA 14 0131012
Molecular Formula : C13H12O3
Molecular Weight : 216.24
stdClass Object
(
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[catalogue_number] => PA 14 0131013
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[chemical_name] =>
[weight] => 302.37
[form] => C18H22O4
[cas] => 2601735-81-1
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2-(6-(3-Hydroxy-2,2-dimethylpropoxy)naphthalen-2-yl)propanoic Acid
Catalogue No.:PA 14 0131013
Molecular Formula : C18H22O4
Molecular Weight : 302.37
stdClass Object
(
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[catalogue_number] => PA USP1457414
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[weight] => NA
[form] => NA
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Naproxen Related Compound K (1457414)
stdClass Object
(
[pname] => Naproxen Chloride
[catalogue_number] => PA 14 0131015
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 248.71
[form] => C14H13ClO2
[cas] => 51091-84-0
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Catalogue No.:PA 14 0131015
Molecular Formula : C14H13ClO2
Molecular Weight : 248.71
stdClass Object
(
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[catalogue_number] => PA 14 0131016
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 513.63
[form] => C32H35NO5
[cas] => NA
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2-(2-(6-Methoxynaphthalen-2-yl)propanamido)butyl 2-(6-methoxynaphthalen-2-yl)propanoate
Catalogue No.:PA 14 0131016
Molecular Formula : C32H35NO5
Molecular Weight : 513.63
stdClass Object
(
[pname] => Naproxen 13CD3
[catalogue_number] => PA STI 089313
[category_ids] => ,98,75,76,78,70,82,
[chemical_name] =>
[weight] => 234.27
[form] => C1313CH11D3O3
[cas] => 1261392-52-2
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Catalogue No.:PA STI 089313
Molecular Formula : C1313CH11D3O3
Molecular Weight : 234.27
stdClass Object
(
[pname] => Naproxen Butanolamide
[catalogue_number] => PA 14 0131017
[category_ids] => ,75,78,70,82,
[chemical_name] =>
[weight] => 301.39
[form] => C18H23NO3
[cas] => 2058179-15-8
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Catalogue No.:PA 14 0131017
Molecular Formula : C18H23NO3
Molecular Weight : 301.39
stdClass Object
(
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[category_ids] => ,162,75,76,78,70,82,
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[weight] => 228.05
[form] => C8H6BrNO2
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)
trans-2-Bromo-β-nitrostyrene
Catalogue No.:PA 14 0131018
Molecular Formula : C8H6BrNO2
Molecular Weight : 228.05
