Risdiplam

Risdiplam is an oral mRNA splicing modifier used in the treatment of spinal muscular atrophy (SMA). Reference standards of Risdiplam API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => tert-Butyl 7-(2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate
    [catalogue_number] => PA 18 1411000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 372.43
    [form] => C19H24N4O4
    [cas] => 2133298-72-1
    [pslug] => 2133298-72-1-tert-butyl-7-2-hydroxy-4-oxo-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411000
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PA 18 1411000

tert-Butyl 7-(2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate

  • Catalogue No.:PA 18 1411000

  • CAS :

    2133298-72-1

  • Molecular Formula : C19H24N4O4

  • Molecular Weight : 372.43

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Details 
stdClass Object
(
    [pname] => tert-Butyl 7-(4-oxo-2-(tosyloxy)-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate
    [catalogue_number] => PA 18 1411001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 526.61
    [form] => C26H30N4O6S
    [cas] => 2133298-73-2
    [pslug] => 2133298-73-2-tert-butyl-7-4-oxo-2-tosyloxy-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411001
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PA 18 1411001

tert-Butyl 7-(4-oxo-2-(tosyloxy)-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate

  • Catalogue No.:PA 18 1411001

  • CAS :

    2133298-73-2

  • Molecular Formula : C26H30N4O6S

  • Molecular Weight : 526.61

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stdClass Object
(
    [pname] => tert-Butyl 7-(2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate
    [catalogue_number] => PA 18 1411002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 501.59
    [form] => C27H31N7O3
    [cas] => 2133298-74-3
    [pslug] => 2133298-74-3-tert-butyl-7-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-4-oxo-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411002
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PA 18 1411002

tert-Butyl 7-(2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate

  • Catalogue No.:PA 18 1411002

  • CAS :

    2133298-74-3

  • Molecular Formula : C27H31N7O3

  • Molecular Weight : 501.59

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Details 
stdClass Object
(
    [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one
    [catalogue_number] => PA 18 1411003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 309.3
    [form] => C16H12FN5O
    [cas] => 1825352-87-1
    [pslug] => 1825352-87-1-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-fluoro-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411003
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PA 18 1411003

2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one

  • Catalogue No.:PA 18 1411003

  • CAS :

    1825352-87-1

  • Molecular Formula : C16H12FN5O

  • Molecular Weight : 309.3

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Details 
stdClass Object
(
    [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-hydroxy-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
    [catalogue_number] => PA 18 1411004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 417.47
    [form] => C22H23N7O2
    [cas] => 2250441-24-6
    [pslug] => 2250441-24-6-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-4-hydroxy-4-7-diazaspiro-2-5-octan-7-yl-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411004
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PA 18 1411004

2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-hydroxy-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

  • Catalogue No.:PA 18 1411004

  • CAS :

    2250441-24-6

  • Molecular Formula : C22H23N7O2

  • Molecular Weight : 417.47

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Details 
stdClass Object
(
    [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-nitroso-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
    [catalogue_number] => PA 18 1411009
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 430.47
    [form] => C22H22N8O2
    [cas] => NA
    [pslug] => 2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-4-nitroso-4-7-diazaspiro-2-5-octan-7-yl-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411009
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PA 18 1411009

2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-nitroso-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

  • Catalogue No.:PA 18 1411009

  • CAS :

    NA

  • Molecular Formula : C22H22N8O2

  • Molecular Weight : 430.47

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Details 
stdClass Object
(
    [pname] => tert-Butyl 4-nitroso-4,7-diazaspiro[2.5]octane-7-carboxylate
    [catalogue_number] => PA 18 1411010
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 241.29
    [form] => C11H19N3O3
    [cas] => NA
    [pslug] => tert-butyl-4-nitroso-4-7-diazaspiro-2-5-octane-7-carboxylate-pa181411010
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PA 18 1411010

tert-Butyl 4-nitroso-4,7-diazaspiro[2.5]octane-7-carboxylate

  • Catalogue No.:PA 18 1411010

  • CAS :

    NA

  • Molecular Formula : C11H19N3O3

  • Molecular Weight : 241.29

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CPHI INDIA- 28, 30 November