roflumilast
Roflumilast is used in the prevention of lung attacks in severe COPD. It is a long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4).Reference standards of Roflumilast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Roflumilast N-Oxide
[catalogue_number] => PA 18 15530
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[weight] => 419.21
[form] => C17H14Cl2F2N2O4
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Catalogue No.:PA 18 15530
Molecular Formula : C17H14Cl2F2N2O4
Molecular Weight : 419.21
stdClass Object
(
[pname] => 5-Dechloro Roflumilast
[catalogue_number] => PA 18 15510
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[chemical_name] =>
[weight] => 368.76
[form] => C17H15ClF2N2O3
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Catalogue No.:PA 18 15510
Molecular Formula : C17H15ClF2N2O3
Molecular Weight : 368.76
stdClass Object
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[pname] => 3-O-Decyclopropyl Roflumilast
[catalogue_number] => PA 18 15520
[category_ids] => ,80,71,75,81,78,70,82,
[chemical_name] =>
[weight] => 349.12
[form] => C13H8Cl2F2N2O3
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3-O-Decyclopropyl Roflumilast
Catalogue No.:PA 18 15520
Molecular Formula : C13H8Cl2F2N2O3
Molecular Weight : 349.12
stdClass Object
(
[pname] => Roflumilast Carboxylic Acid Impurity
[catalogue_number] => PA 18 15540
[category_ids] => ,80,75,70,
[chemical_name] =>
[weight] => 258.22
[form] => C12H12F2O4
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Roflumilast Carboxylic Acid Impurity
Catalogue No.:PA 18 15540
Molecular Formula : C12H12F2O4
Molecular Weight : 258.22
stdClass Object
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[pname] => 3,4-Di(cyclopropylmethoxy) Roflumilast
[catalogue_number] => PA 18 15570
[category_ids] => ,80,71,75,81,78,70,82,
[chemical_name] =>
[weight] => 407.29
[form] => C20H20Cl2N2O3
[cas] => 1391052-24-6
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3,4-Di(cyclopropylmethoxy) Roflumilast
Catalogue No.:PA 18 15570
Molecular Formula : C20H20Cl2N2O3
Molecular Weight : 407.29
stdClass Object
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[pname] => 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast
[catalogue_number] => PA 18 15580
[category_ids] => ,80,71,75,81,78,70,82,
[chemical_name] =>
[weight] => 403.21
[form] => C17H14Cl2F2N2O3
[cas] => 162401-43-6
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4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast
Catalogue No.:PA 18 15580
Molecular Formula : C17H14Cl2F2N2O3
Molecular Weight : 403.21
stdClass Object
(
[pname] => 3,4-bis(Difluoromethoxy) Roflumilast
[catalogue_number] => PA 18 15590
[category_ids] => ,80,71,75,81,78,70,82,
[chemical_name] =>
[weight] => 399.12
[form] => C14H8Cl2F4N2O3
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3,4-bis(Difluoromethoxy) Roflumilast
Catalogue No.:PA 18 15590
Molecular Formula : C14H8Cl2F4N2O3
Molecular Weight : 399.12
stdClass Object
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[pname] => 3-Cyclobutyl-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
[catalogue_number] => PA 18 15610
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[weight] => 387.21
[form] => C17H14Cl2F2N2O2
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3-Cyclobutyl-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Catalogue No.:PA 18 15610
Molecular Formula : C17H14Cl2F2N2O2
Molecular Weight : 387.21
stdClass Object
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[pname] => 3-(But-3-en-1-yloxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
[catalogue_number] => PA 18 15620
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[weight] => 403.21
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3-(But-3-en-1-yloxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Catalogue No.:PA 18 15620
Molecular Formula : C17H14Cl2F2N2O3
Molecular Weight : 403.21
stdClass Object
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[pname] => 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic-d4 Acid
[catalogue_number] => PA STI 023650
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[weight] => 262.24
[form] => C12H8D4F2O4
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3-Cyclopropylmethoxy-4-difluoromethoxybenzoic-d4 Acid
Catalogue No.:PA STI 023650
Molecular Formula : C12H8D4F2O4
Molecular Weight : 262.24
stdClass Object
(
[pname] => Roflumilast-d4 N-Oxide
[catalogue_number] => PA STI 078310
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[chemical_name] =>
[weight] => 423.23
[form] => C17H10D4Cl2F2N2O4
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Catalogue No.:PA STI 078310
Molecular Formula : C17H10D4Cl2F2N2O4
Molecular Weight : 423.23
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[pname] => 2,5-Dichloropyridin-4-amine
[catalogue_number] => PA 18 15660
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[chemical_name] =>
[weight] => 163
[form] => C5H4Cl2N2
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2,5-Dichloropyridin-4-amine
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[pname] => 2,3-Dichloropyridin-4-amine
[catalogue_number] => PA 18 15670
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[weight] => 163
[form] => C5H4Cl2N2
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2,3-Dichloropyridin-4-amine
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[pname] => 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide
[catalogue_number] => PA 18 0151000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 353.2
[form] => C16H14Cl2N2O3
[cas] => 475271-62-6
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3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide
stdClass Object
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[pname] => N-(3-Bromo-5-chloropyridin-4-yl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamide
[catalogue_number] => PA 18 0151001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 447.66
[form] => C17H14BrClF2N2O3
[cas] => NA
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N-(3-Bromo-5-chloropyridin-4-yl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamide
Catalogue No.:PA 18 0151001
Molecular Formula : C17H14BrClF2N2O3
Molecular Weight : 447.66
stdClass Object
(
[pname] => 5-((3,5-Dichloropyridin-4-yl)carbamoyl)-2-(difluoromethoxy)phenyl dimethylcarbamate
[catalogue_number] => PA 18 0151002
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[chemical_name] =>
[weight] => 420.19
[form] => C16H13Cl2F2N3O4
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5-((3,5-Dichloropyridin-4-yl)carbamoyl)-2-(difluoromethoxy)phenyl dimethylcarbamate
Catalogue No.:PA 18 0151002
Molecular Formula : C16H13Cl2F2N3O4
Molecular Weight : 420.19
stdClass Object
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[pname] => 4-(Difluoromethoxy)-3-Hydroxybenzoic Acid
[catalogue_number] => PA 18 0151003
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[chemical_name] =>
[weight] => 204.13
[form] => C8H6F2O4
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4-(Difluoromethoxy)-3-Hydroxybenzoic Acid
Catalogue No.:PA 18 0151003
Molecular Formula : C8H6F2O4
Molecular Weight : 204.13