sacubitril

An antihypertensive drug, Sacubitril is used in combination with valsartan for the treatment of heart ailments. A prodrug of sacubitrilat which is an inhibitor of enzyme neprilysin, which aids the degradation of blood pressure-lowering peptides, atrial and brain natriuretic peptide.Reference standards of Sacubitril API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
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    [pname] => tert-Butyl (R)-(1-hydroxy-3-(4-iodophenyl)propan-2-yl)carbamate
    [catalogue_number] => PA 19 0661081
    [category_ids] => ,80,75,70,82,78,
    [chemical_name] => 
    [weight] => 377.22
    [form] => C14H20INO3
    [cas] => 210962-92-8
    [pslug] => 210962-92-8-tert-butyl-r-1-hydroxy-3-4-iodophenyl-propan-2-yl-carbamate-pa190661081
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PA 19 0661081

tert-Butyl (R)-(1-hydroxy-3-(4-iodophenyl)propan-2-yl)carbamate


  • Catalogue No.:PA 19 0661081

  • CAS :

    210962-92-8

  • Molecular Formula : C14H20INO3

  • Molecular Weight : 377.22

stdClass Object
(
    [pname] => 5-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-5-oxopentanoic Acid
    [catalogue_number] => PA 19 0661082
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 425.53
    [form] => C25H31NO5
    [cas] => 773820-89-6
    [pslug] => 773820-89-6-5-2s-4r-1-1-1-biphenyl-4-yl-5-ethoxy-4-methyl-5-oxopentan-2-yl-amino-5-oxopentanoic-acid-pa190661082
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PA 19 0661082

5-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-5-oxopentanoic Acid


  • Catalogue No.:PA 19 0661082

  • CAS :

    773820-89-6

  • Molecular Formula : C25H31NO5

  • Molecular Weight : 425.53

stdClass Object
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    [pname] => Methyl 4-([1,1'-biphenyl]-4-yl)-3-oxobutanoate
    [catalogue_number] => PA 19 0661083
    [category_ids] => ,80,75,70,82,78,
    [chemical_name] => 
    [weight] => 268.31
    [form] => C17H16O3
    [cas] => 100160-75-6
    [pslug] => 100160-75-6-methyl-4-1-1-biphenyl-4-yl-3-oxobutanoate-pa190661083
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PA 19 0661083

Methyl 4-([1,1'-biphenyl]-4-yl)-3-oxobutanoate


  • Catalogue No.:PA 19 0661083

  • CAS :

    100160-75-6

  • Molecular Formula : C17H16O3

  • Molecular Weight : 268.31

stdClass Object
(
    [pname] => 5-([1,1'-Biphenyl]-4-yl)-2-methylene-4-oxopentanoic Acid
    [catalogue_number] => PA 19 0661084
    [category_ids] => ,80,75,70,82,78,
    [chemical_name] => 
    [weight] => 280.32
    [form] => C18H16O3
    [cas] => 2454675-99-9
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PA 19 0661084

5-([1,1'-Biphenyl]-4-yl)-2-methylene-4-oxopentanoic Acid


  • Catalogue No.:PA 19 0661084

  • CAS :

    2454675-99-9

  • Molecular Formula : C18H16O3

  • Molecular Weight : 280.32

stdClass Object
(
    [pname] => Ethyl 5-([1,1'-biphenyl]-4-yl)-4-hydroxy-2-methylenepentanoate
    [catalogue_number] => PA 19 0661085
    [category_ids] => ,80,75,70,82,78,
    [chemical_name] => 
    [weight] => 310.39
    [form] => C20H22O3
    [cas] => 3059070-67-3
    [pslug] => 3059070-67-3-ethyl-5-1-1-biphenyl-4-yl-4-hydroxy-2-methylenepentanoate-pa190661085
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PA 19 0661085

Ethyl 5-([1,1'-biphenyl]-4-yl)-4-hydroxy-2-methylenepentanoate


  • Catalogue No.:PA 19 0661085

  • CAS :

    3059070-67-3

  • Molecular Formula : C20H22O3

  • Molecular Weight : 310.39

stdClass Object
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    [pname] => Ethyl 5-([1,1'-biphenyl]-4-yl)-2-methylene-4-oxopentanoate
    [catalogue_number] => PA 19 0661086
    [category_ids] => ,80,75,70,82,78,
    [chemical_name] => 
    [weight] => 308.38
    [form] => C20H20O3
    [cas] => 3038727-90-8
    [pslug] => 3038727-90-8-ethyl-5-1-1-biphenyl-4-yl-2-methylene-4-oxopentanoate-pa190661086
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PA 19 0661086

Ethyl 5-([1,1'-biphenyl]-4-yl)-2-methylene-4-oxopentanoate


  • Catalogue No.:PA 19 0661086

  • CAS :

    3038727-90-8

  • Molecular Formula : C20H20O3

  • Molecular Weight : 308.38

stdClass Object
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    [pname] => Ethyl 5-([1,1'-biphenyl]-4-yl)-2-methyl-4-oxopent-2-enoate
    [catalogue_number] => PA 19 0661087
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    [chemical_name] => 
    [weight] => 308.38
    [form] => C20H20O3
    [cas] => 3038727-89-5
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PA 19 0661087

Ethyl 5-([1,1'-biphenyl]-4-yl)-2-methyl-4-oxopent-2-enoate


  • Catalogue No.:PA 19 0661087

  • CAS :

    3038727-89-5

  • Molecular Formula : C20H20O3

  • Molecular Weight : 308.38

CPHI INDIA- 28, 30 November