saxagliptin
Saxagliptin is used as monotherapy or in combination with other drugs for the treatment of type 2 diabetes. It is an oral hypoglycemic SaxagliptinIt, it is sold under the brand name Onglyza.Reference standards of Saxagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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(2S,2R',trans)-Saxagliptin
Catalogue No.:PA 19 40520
Molecular Formula : C18H25N3O2
Molecular Weight : 315.41
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(2'S,2R,trans)-Saxagliptin
Catalogue No.:PA 19 40530
Molecular Formula : C18H25N3O2
Molecular Weight : 315.41
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(2S,2S',trans)-Saxagliptin
Catalogue No.:PA 19 40540
Molecular Formula : C18H25N3O2
Molecular Weight : 315.41
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Catalogue No.:PA 19 40550
Molecular Formula : C19H25N3O3
Molecular Weight : 343.42
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Catalogue No.:PA 19 40620
Molecular Formula : C18H25N3O2
Molecular Weight : 315.41
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Saxagliptin Monohydrate - Impurity A
Catalogue No.:PA 19 40630
Molecular Formula : C18H25N3O2
Molecular Weight : 315.41
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Saxagliptin 3-Deoxy Impurity
Catalogue No.:PA 19 40640
Molecular Formula : C18H25N3O
Molecular Weight : 299.41
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Catalogue No.:PA 19 40650
Molecular Formula : C18H25N3O2
Molecular Weight : 315.41
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(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate
Catalogue No.:PA 19 40660
Molecular Formula : C7H14N2O4S
Molecular Weight : 222.26
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(2S)-2-((tert-Butoxycarbonyl)amino)-2-((1s,3R,5S,7R)-4-hydroxyadamantan-1-yl)acetic Acid
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(1S,3R,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate
Catalogue No.:PA 19 40690
Molecular Formula : C7H14N2O4S
Molecular Weight : 222.26
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(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate
Catalogue No.:PA 19 40700
Molecular Formula : C7H14N2O4S
Molecular Weight : 222.26
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(2'R,2R,trans)-Saxagliptin
Catalogue No.:PA 19 40770
Molecular Formula : C18H25N3O2
Molecular Weight : 315.41
stdClass Object
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(R)-2-((S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)succinic Acid
Catalogue No.:PA 19 40780
Molecular Formula : C22H28N2O6
Molecular Weight : 416.47
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[catalogue_number] => PA 19 40790
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(S)-N-Boc-3-hydroxyadamantylglycine-L-cis-4,5-methanoprolinamide
Catalogue No.:PA 19 40790
Molecular Formula : C23H35N3O5
Molecular Weight : 433.55
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Catalogue No.:PA 19 40800
Molecular Formula : C23H33N3O4
Molecular Weight : 415.53
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Saxagliptin Monohydrate - Impurity B
Catalogue No.:PA 19 40810
Molecular Formula : C18H27N3O3
Molecular Weight : 333.43
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Saxagliptin Monohydrate - Impurity C
Catalogue No.:PA 19 40820
Molecular Formula : C18H24N2O3
Molecular Weight : 316.39
stdClass Object
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(1S,3R,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carboxamide
Catalogue No.:PA 19 40830
Molecular Formula : C18H27N3O3
Molecular Weight : 333.43
stdClass Object
(
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[catalogue_number] => PA 19 40840
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3-((S)-1-Amino-2-((1S,3R,5S),-3-cyano-2-aza-biclyclo[3.1.0]hexan-2-yl)-2-oxoethyl)adamantan-1-yl-2,2,2-trichloroacetate
Catalogue No.:PA 19 40840
Molecular Formula : C20H24Cl3N3O3
Molecular Weight : 460.78
stdClass Object
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[weight] => 334.39
[form] => C1513C3H25N3O3
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Catalogue No.:PA STI 051620
Molecular Formula : C1513C3H25N3O3
Molecular Weight : 334.39
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(2’S,2R,cis)-Saxagliptin
Catalogue No.:PA 19 40850
Molecular Formula : C18H25N3O2
Molecular Weight : 315.42
stdClass Object
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[weight] => 323.39
[form] => C17H25NO5
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(S)-2-((tert-Butoxycarbonyl)amino)-2-((1s,3R,5S,7R)-4-oxoadamantan-1-yl)acetic Acid
Catalogue No.:PA 19 40860
Molecular Formula : C17H25NO5
Molecular Weight : 323.39
stdClass Object
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[pname] => 2-Adamantanone-5-carboxylic Acid
[catalogue_number] => PA 19 40870
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[weight] => 194.23
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2-Adamantanone-5-carboxylic Acid
Catalogue No.:PA 19 40870
Molecular Formula : C11H14O3
Molecular Weight : 194.23
stdClass Object
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(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetic Acid
Catalogue No.:PA 19 0401000
Molecular Formula : C8H11F3N2O3
Molecular Weight : 240.18
stdClass Object
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(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetic Acid
Catalogue No.:PA 19 0401001
Molecular Formula : C8H11F3N2O3
Molecular Weight : 240.18
stdClass Object
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[catalogue_number] => PA 19 0401003
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[chemical_name] =>
[weight] => 351.88
[form] => C18H26ClN3O2
[cas] => NA
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(1S,3S,5S)-2-((R)-2-Amino-2-((1r,3S,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
Catalogue No.:PA 19 0401003
Molecular Formula : C18H26ClN3O2
Molecular Weight : 351.88
stdClass Object
(
[pname] => (1S,3R,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
[catalogue_number] => PA 19 0401004
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[weight] => 351.88
[form] => C18H26ClN3O2
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(1S,3R,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
Catalogue No.:PA 19 0401004
Molecular Formula : C18H26ClN3O2
Molecular Weight : 351.88
stdClass Object
(
[pname] => Saxagliptin O-Sulfate
[catalogue_number] => PA 19 0401005
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 395.47
[form] => C18H25N3O5S
[cas] => 1429782-94-4
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Catalogue No.:PA 19 0401005
Molecular Formula : C18H25N3O5S
Molecular Weight : 395.47
stdClass Object
(
[pname] => Saxagliptin N-Carboxybenzyl
[catalogue_number] => PA 19 0401006
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[weight] => 449.55
[form] => C26H31N3O4
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Saxagliptin N-Carboxybenzyl
Catalogue No.:PA 19 0401006
Molecular Formula : C26H31N3O4
Molecular Weight : 449.55
stdClass Object
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(2R,2’R,cis)-Deoxy-saxagliptin
Catalogue No.:PA 19 0401007
Molecular Formula : C18H25N3O
Molecular Weight : 299.42
stdClass Object
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(2R,2’R,trans)-Deoxy-saxagliptin
Catalogue No.:PA 19 0401008
Molecular Formula : C18H25N3O
Molecular Weight : 299.42
stdClass Object
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(2R,2’S,cis)-Deoxy-saxagliptin
Catalogue No.:PA 19 0401009
Molecular Formula : C18H25N3O
Molecular Weight : 299.42
stdClass Object
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[pname] => (2S,2’R,cis)-7-Hydroxy-saxagliptin
[catalogue_number] => PA 19 0401010
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[weight] => 331.42
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(2S,2’R,cis)-7-Hydroxy-saxagliptin
Catalogue No.:PA 19 0401010
Molecular Formula : C18H25N3O3
Molecular Weight : 331.42
stdClass Object
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(2R,2’R,Trans)-7-Hydroxy-saxagliptin
Catalogue No.:PA 19 0401011
Molecular Formula : C18H25N3O3
Molecular Weight : 331.42
stdClass Object
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(2S,2’S,Trans)-7-Hydroxy-saxagliptin
Catalogue No.:PA 19 0401012
Molecular Formula : C18H25N3O3
Molecular Weight : 331.42
stdClass Object
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(2R,2’R,cis)-7-Hydroxy-saxagliptin
Catalogue No.:PA 19 0401013
Molecular Formula : C18H25N3O3
Molecular Weight : 331.42
stdClass Object
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[weight] => 241.29
[form] => C12H19NO4
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(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic Acid
Catalogue No.:PA 19 0401014
Molecular Formula : C12H19NO4
Molecular Weight : 241.29
stdClass Object
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[weight] => 232.28
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Catalogue No.:PA 19 0401015
Molecular Formula : C10H20N2O4
Molecular Weight : 232.28
stdClass Object
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(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
Catalogue No.:PA 19 0401016
Molecular Formula : C11H17NO4
Molecular Weight : 227.26
stdClass Object
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(E)-4-(((1S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)amino)-4-oxobut-2-enoic acid
Catalogue No.:PA 19 0401017
Molecular Formula : C22H27N3O5
Molecular Weight : 413.47
stdClass Object
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(1S,3S,5S)-2-((2S)-2-(((3R,4R,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-2-((3R,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile
stdClass Object
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(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide
Catalogue No.:PA 19 0401019
Molecular Formula : C6H10N2O
Molecular Weight : 126.16
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[form] => C6H10N2O
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(1S,3R,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide
Catalogue No.:PA 19 0401020
Molecular Formula : C6H10N2O
Molecular Weight : 126.16
stdClass Object
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[pname] => 3-Hydroxyadamantane-1-carboxylic acid
[catalogue_number] => PA 19 0401021
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[chemical_name] =>
[weight] => 196.25
[form] => C11H16O3
[cas] => 42711-75-1
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3-Hydroxyadamantane-1-carboxylic acid
Catalogue No.:PA 19 0401021
Molecular Formula : C11H16O3
Molecular Weight : 196.25
stdClass Object
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[pname] => (1R, 3S, 5S, 2'R)-Saxagliptin
[catalogue_number] => PA 19 0401022
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[chemical_name] =>
[weight] => 315.42
[form] => C18H25N3O2
[cas] => NA
[pslug] => 1r-3s-5s-2r-saxagliptin-pa190401022
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(1R, 3S, 5S, 2'R)-Saxagliptin
Catalogue No.:PA 19 0401022
Molecular Formula : C18H25N3O2
Molecular Weight : 315.42
stdClass Object
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[pname] => (1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate
[catalogue_number] => PA 19 0401023
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[chemical_name] =>
[weight] => 222.26
[form] => C7H14N2O4S
[cas] => 1312338-82-1
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(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate
Catalogue No.:PA 19 0401023
Molecular Formula : C7H14N2O4S
Molecular Weight : 222.26
stdClass Object
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[pname] => (1R,3R,5R)-2-Nitroso-2-azabicyclo[3.1.0]hexane-3-carbonitrile
[catalogue_number] => PA 19 0401024
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[chemical_name] =>
[weight] => 137.14
[form] => C6H7N3O
[cas] => NA
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(1R,3R,5R)-2-Nitroso-2-azabicyclo[3.1.0]hexane-3-carbonitrile
Catalogue No.:PA 19 0401024
Molecular Formula : C6H7N3O
Molecular Weight : 137.14
stdClass Object
(
[pname] => (1R,3S,5R)-2-((2S)-2-(3-Hydroxyadamantan-1-yl)-2-(tritylamino)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile
[catalogue_number] => PA 19 0401026
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 557.74
[form] => C37H39N3O2
[cas] => NA
[pslug] => 1r-3s-5r-2-2s-2-3-hydroxyadamantan-1-yl-2-tritylamino-acetyl-2-azabicyclo-3-1-0-hexane-3-carbonitrile-pa190401026
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(1R,3S,5R)-2-((2S)-2-(3-Hydroxyadamantan-1-yl)-2-(tritylamino)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile
Catalogue No.:PA 19 0401026
Molecular Formula : C37H39N3O2
Molecular Weight : 557.74
stdClass Object
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[pname] => (1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
[catalogue_number] => PA 19 0401025
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[chemical_name] =>
[weight] => 227.26
[form] => C11H17NO4
[cas] => 197142-34-0
[pslug] => 197142-34-0-1r-3s-5r-2-tert-butoxycarbonyl-2-azabicyclo-3-1-0-hexane-3-carboxylic-acid-pa190401025
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(1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
Catalogue No.:PA 19 0401025
Molecular Formula : C11H17NO4
Molecular Weight : 227.26
stdClass Object
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[pname] => (S)-2-((3S,5S,7S)-Adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetonitrile
[catalogue_number] => PA 19 0401027
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[chemical_name] =>
[weight] => 310.44
[form] => C20H26N2O
[cas] => 361441-95-4
[pslug] => 361441-95-4-s-2-3s-5s-7s-adamantan-1-yl-2-r-2-hydroxy-1-phenylethyl-amino-acetonitrile-pa190401027
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(S)-2-((3S,5S,7S)-Adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetonitrile
Catalogue No.:PA 19 0401027
Molecular Formula : C20H26N2O
Molecular Weight : 310.44
