sofosbuvir
A recently approved nucleotide analog used in the treatment of hepatitis. Sofosbuvir works by inhibiting the hepatitis C NS5B protein. It is a a prodrug of its active antiviral agent GS-461203 Reference standards of Sofosbuvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Sofosbuvir Nucleoside Derivative
[catalogue_number] => PA 19 51510
[category_ids] => ,69,70,75,76,78,79,82,
[chemical_name] =>
[weight] => 260.22
[form] => C10H13FN2O5
[cas] => 863329-66-2
[pslug] => 863329-66-2-sofosbuvir-nucleoside-derivative-pa1951510
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Sofosbuvir Nucleoside Derivative
Catalogue No.:PA 19 51510
Molecular Formula : C10H13FN2O5
Molecular Weight : 260.22
stdClass Object
(
[pname] => Sofosbuvir (R)-Phosphate
[catalogue_number] => PA 19 51770
[category_ids] => 85,83,82,78,75,71,70
[chemical_name] =>
[weight] => 529.45
[form] => C22H29FN3O9P
[cas] => 1190308-01-0
[pslug] => 1190308-01-0-sofosbuvir-r-phosphate-pa1951770
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Catalogue No.:PA 19 51770
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
(
[pname] => D-Alanine Sofosbuvir
[catalogue_number] => PA 19 51780
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[chemical_name] =>
[weight] => 529.45
[form] => C22H29FN3O9P
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[pslug] => 1064684-71-4-d-alanine-sofosbuvir-pa1951780
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Catalogue No.:PA 19 51780
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
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[pname] => Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-Dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
[catalogue_number] => PA 19 51790
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Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-Dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 51790
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
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[pname] => (R)-Isopropyl 2-(((R)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
[catalogue_number] => PA 19 51800
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(R)-Isopropyl 2-(((R)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Catalogue No.:PA 19 51800
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
(
[pname] => (S)-Sofosbuvir Pentafluorophenoxy Analogue
[catalogue_number] => PA 19 51810
[category_ids] => 85,83,82,78,75,71,70
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[weight] => 453.3
[form] => C18H17F5NO5P
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(S)-Sofosbuvir Pentafluorophenoxy Analogue
stdClass Object
(
[pname] => Chloro Sofosbuvir
[catalogue_number] => PA 19 51820
[category_ids] => ,79,80,71,76,75,85,83,78,70,82,72,
[chemical_name] =>
[weight] => 545.91
[form] => C22H29ClN3O9P
[cas] => 1496552-51-2
[pslug] => 1496552-51-2-chloro-sofosbuvir-pa1951820
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Catalogue No.:PA 19 51820
Molecular Formula : C22H29ClN3O9P
Molecular Weight : 545.91
stdClass Object
(
[pname] => Sofosbuvir 3',5'-Bis-(S)-phosphate
[catalogue_number] => PA 19 51830
[category_ids] => 85,83,82,78,75,71,70
[chemical_name] =>
[weight] => 798.69
[form] => C34H45FN4O13P2
[cas] => 1337482-17-3
[pslug] => 1337482-17-3-sofosbuvir-3-5-bis-s-phosphate-pa1951830
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Sofosbuvir 3',5'-Bis-(S)-phosphate
Catalogue No.:PA 19 51830
Molecular Formula : C34H45FN4O13P2
Molecular Weight : 798.69
stdClass Object
(
[pname] => Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]
[catalogue_number] => PA 19 51840
[category_ids] => ,71,75,85,83,78,70,82,
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[weight] => 529.45
[form] => C22H29FN3O9P
[cas] => 1337482-15-1
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Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]
Catalogue No.:PA 19 51840
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
(
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[catalogue_number] => PA 19 51850
[category_ids] => ,71,75,85,83,78,70,82,
[chemical_name] =>
[weight] => 416.29
[form] => C16H18FN2O8P
[cas] => 1859162-80-3
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((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl Phenyl Hydrogen Phosphate
Catalogue No.:PA 19 51850
Molecular Formula : C16H18FN2O8P
Molecular Weight : 416.29
stdClass Object
(
[pname] => Sofosbuvir α-Isomer
[catalogue_number] => PA 19 51860
[category_ids] => ,71,75,85,83,78,70,82,72,
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[weight] => 529.45
[form] => C22H29FN3O9P
[cas] => NA
[pslug] => sofosbuvir-alpha-isomer-pa1951860
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Catalogue No.:PA 19 51860
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
(
[pname] => (2R,3S,4S,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
[catalogue_number] => PA 19 51870
[category_ids] => ,71,75,85,83,78,70,82,
[chemical_name] =>
[weight] => 571.55
[form] => C31H26FN3O7
[cas] => NA
[pslug] => 2r-3s-4s-5s-5-4-benzamido-2-oxopyrimidin-1-2h-yl-2-benzoyloxy-methyl-4-fluoro-4-methyltetrahydrofuran-3-yl-benzoate-pa1951870
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(2R,3S,4S,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
Catalogue No.:PA 19 51870
Molecular Formula : C31H26FN3O7
Molecular Weight : 571.55
stdClass Object
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[pname] => (S)-Isopropyl 2-(((S)-(((2S,3S,4S,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
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(S)-Isopropyl 2-(((S)-(((2S,3S,4S,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Catalogue No.:PA 19 51880
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
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[pname] => (R)-Isopropyl 2-(((R)-(((2S,3S,4S,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
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(R)-Isopropyl 2-(((R)-(((2S,3S,4S,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Catalogue No.:PA 19 51890
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
(
[pname] => (S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;
[catalogue_number] => PA 19 51900
[category_ids] => ,80,79,75,78,70,82,
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[weight] => 515.43
[form] => C21H27FN3O9P
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(S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;
Catalogue No.:PA 19 51900
Molecular Formula : C21H27FN3O9P
Molecular Weight : 515.43
stdClass Object
(
[pname] => Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
[catalogue_number] => PA 19 0511000
[category_ids] => ,78,75,76,82,
[chemical_name] =>
[weight] => 529.46
[form] => C22H29FN3O9P
[cas] => NA
[pslug] => -isopropyl-r-2r-3r-4r-5r-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl-methoxy-phenoxy-phosphoryl-d-alaninate-pa190511000
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Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
Catalogue No.:PA 19 0511000
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.46
stdClass Object
(
[pname] => O-Desphenyl Sofosbuvir
[catalogue_number] => PA 19 0511001
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 453.36
[form] => C16H25FN3O9P
[cas] => 1233335-82-4
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Catalogue No.:PA 19 0511001
Molecular Formula : C16H25FN3O9P
Molecular Weight : 453.36
stdClass Object
(
[pname] => Methyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
[catalogue_number] => PA 19 0511002
[category_ids] => ,70,75,76,78,82,
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[weight] => 501.4
[form] => C20H25FN3O9P
[cas] => 1394157-28-8
[pslug] => 1394157-28-8-methyl-r-2r-3r-4r-5r-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl-methoxy-phenoxy-phosphoryl-l-alaninate-pa190511002
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Methyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
stdClass Object
(
[pname] => Sofosbuvir o-desisopropyl o-methyl ester
[catalogue_number] => PA 19 0511007
[category_ids] => ,94,91,75,76,78,70,82,
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[weight] => 501.4
[form] => C20H25FN3O9P
[cas] => 1015255-46-5
[pslug] => 1015255-46-5-sofosbuvir-o-desisopropyl-o-methyl-ester-pa190511007
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Sofosbuvir o-desisopropyl o-methyl ester
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[catalogue_number] => PA 19 0511003
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[weight] => 164.13
[form] => C6H9FO4
[cas] => 1040882-61-8
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(3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511003
Molecular Formula : C6H9FO4
Molecular Weight : 164.13
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[pname] => (3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
[catalogue_number] => PA 19 0511004
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[weight] => 164.13
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(3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511004
Molecular Formula : C6H9FO4
Molecular Weight : 164.13
stdClass Object
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[pname] => (3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
[catalogue_number] => PA 19 0511005
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[chemical_name] =>
[weight] => 164.13
[form] => C6H9FO4
[cas] => 1622930-61-3
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(3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511005
Molecular Formula : C6H9FO4
Molecular Weight : 164.13
stdClass Object
(
[pname] => (3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
[catalogue_number] => PA 19 0511006
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[chemical_name] =>
[weight] => 162.14
[form] => C6H10O5
[cas] => 492-30-8
[pslug] => 492-30-8-3r-4r-5r-3-4-dihydroxy-5-hydroxymethyl-3-methyldihydrofuran-2-3h-one-pa190511006
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(3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511006
Molecular Formula : C6H10O5
Molecular Weight : 162.14
stdClass Object
(
[pname] => Isopropyl ((S)-(((2R,3R,4S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
[catalogue_number] => PA 19 0511009
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 527.47
[form] => C22H30N3O10P
[cas] => 1987957-11-8
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Isopropyl ((S)-(((2R,3R,4S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511009
Molecular Formula : C22H30N3O10P
Molecular Weight : 527.47
stdClass Object
(
[pname] => ((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl)methyl benzoate
[catalogue_number] => PA 19 0511010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 374.36
[form] => C20H19FO6
[cas] => 1884385-12-9
[pslug] => 1884385-12-9-2r-3r-4r-3-benzoyloxy-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl-methyl-benzoate-pa190511010
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((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl)methyl benzoate
Catalogue No.:PA 19 0511010
Molecular Formula : C20H19FO6
Molecular Weight : 374.36
stdClass Object
(
[pname] => (2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-chloro-4-methyltetrahydrofuran-3-yl benzoate
[catalogue_number] => PA 19 0511011
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 588.01
[form] => C31H26ClN3O7
[cas] => 1496551-70-2
[pslug] => 1496551-70-2-2r-3r-4r-5r-5-4-benzamido-2-oxopyrimidin-1-2h-yl-2-benzoyloxy-methyl-4-chloro-4-methyltetrahydrofuran-3-yl-benzoate-pa190511011
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(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-chloro-4-methyltetrahydrofuran-3-yl benzoate
Catalogue No.:PA 19 0511011
Molecular Formula : C31H26ClN3O7
Molecular Weight : 588.01
stdClass Object
(
[pname] => ((2R,3R,4S)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
[catalogue_number] => PA 19 0511013
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 372.35
[form] => C20H17FO6
[cas] => 1157884-58-6
[pslug] => 1157884-58-6-2r-3r-4s-3-benzoyloxy-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl-methyl-benzoate-pa190511013
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((2R,3R,4S)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
Catalogue No.:PA 19 0511013
Molecular Formula : C20H17FO6
Molecular Weight : 372.35
stdClass Object
(
[pname] => Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
[catalogue_number] => PA 19 0511008
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 529.46
[form] => C22H29FN3O9P
[cas] => 1496552-28-3
[pslug] => 1496552-28-3-isopropyl-s-2r-3r-4r-5r-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl-methoxy-phenoxy-phosphoryl-d-alaninate-pa190511008
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Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
Catalogue No.:PA 19 0511008
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.46
stdClass Object
(
[pname] => 9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-1H-purine-2,6-dithione
[catalogue_number] => PA 19 0511014
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 316.35
[form] => C10H12N4O4S2
[cas] => 56496-81-2
[pslug] => 56496-81-2-9-2r-3r-4s-5r-3-4-dihydroxy-5-hydroxymethyl-tetrahydrofuran-2-yl-3-9-dihydro-1h-purine-2-6-dithione-pa190511014
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9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-1H-purine-2,6-dithione
Catalogue No.:PA 19 0511014
Molecular Formula : C10H12N4O4S2
Molecular Weight : 316.35
stdClass Object
(
[pname] => L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester
[catalogue_number] => PA 19 0511015
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 453.3
[form] => C18H17F5NO5P
[cas] => 1337529-56-2
[pslug] => 1337529-56-2-l-alanine-n-r-2-3-4-5-6-pentafluorophenoxy-phenoxyphosphinyl-1-methylethyl-ester-pa190511015
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L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester
stdClass Object
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[pname] => ((2R,3R,4R)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate
[catalogue_number] => PA 19 0511017
[category_ids] => ,75,78,70,82,
[chemical_name] =>
[weight] => 392.81
[form] => C20H18ClFO5
[cas] => 1621160-31-3
[pslug] => 1621160-31-3-2r-3r-4r-3-benzoyloxy-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl-methyl-benzoate-pa190511017
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((2R,3R,4R)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate
Catalogue No.:PA 19 0511017
Molecular Formula : C20H18ClFO5
Molecular Weight : 392.81
