ticagrelor

A P2Y12 receptor antagonist drug, used as a platelet aggregation inhibitor. Ticagrelor is a nucleoside analogue used in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases. Reference standards of Ticagrelor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => rel-2-(3-Ethoxy-4-fluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111104
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 231.7
    [form] => C11H15ClFNO
    [cas] => 2055841-10-4
    [pslug] => 2055841-10-4-rel-2-3-ethoxy-4-fluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111104
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PA 47 0111104

rel-2-(3-Ethoxy-4-fluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111104

  • CAS :

    2055841-10-4

  • Molecular Formula : C11H15ClFNO

  • Molecular Weight : 231.7

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Details 
stdClass Object
(
    [pname] => 2-(((3aR,4S,6R,6aS)-6-(7-Chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
    [catalogue_number] => PA 47 0111105
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 429.92
    [form] => C17H24ClN5O4S
    [cas] => 376608-75-2
    [pslug] => 376608-75-2-2-3ar-4s-6r-6as-6-7-chloro-5-propylthio-3h-1-2-3-triazolo-4-5-d-pyrimidin-3-yl-2-2-dimethyltetrahydro-4h-cyclopenta-d-1-3-dioxol-4-yl-oxy-ethan-1-ol-pa470111105
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PA 47 0111105

2-(((3aR,4S,6R,6aS)-6-(7-Chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

  • Catalogue No.:PA 47 0111105

  • CAS :

    376608-75-2

  • Molecular Formula : C17H24ClN5O4S

  • Molecular Weight : 429.92

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Details 
stdClass Object
(
    [pname] => N-(5-Amino-6-chloro-2-(propylsulfinyl)pyrimidin-4-yl)-N-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)nitrous amide
    [catalogue_number] => PA 47 0111107
    [category_ids] => ,75,76,78,70,82,162,
    [chemical_name] => 
    [weight] => 423.87
    [form] => C14H22ClN5O6S
    [cas] => NA
    [pslug] => n-5-amino-6-chloro-2-propylsulfinyl-pyrimidin-4-yl-n-1r-2s-3s-4s-2-3-dihydroxy-4-2-hydroxyethoxy-cyclopentyl-nitrous-amide-pa470111107
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PA 47 0111107

N-(5-Amino-6-chloro-2-(propylsulfinyl)pyrimidin-4-yl)-N-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)nitrous amide

  • Catalogue No.:PA 47 0111107

  • CAS :

    NA

  • Molecular Formula : C14H22ClN5O6S

  • Molecular Weight : 423.87

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Details 
stdClass Object
(
    [pname] => N-(2-(3,4-Difluorophenyl)cyclopropyl)-N-(5-(propylthio)-3-((1R,2S,3S,4R)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous Amide
    [catalogue_number] => PA 47 0111114
    [category_ids] => ,70,71,75,78,79,82,162,
    [chemical_name] => 
    [weight] => 507.52
    [form] => C21H23F2N7O4S
    [cas] => NA
    [pslug] => n-2-3-4-difluorophenyl-cyclopropyl-n-5-propylthio-3-1r-2s-3s-4r-2-3-4-trihydroxycyclopentyl-3h-1-2-3-triazolo-4-5-d-pyrimidin-7-yl-nitrous-amide-pa470111114
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PA 47 0111114

N-(2-(3,4-Difluorophenyl)cyclopropyl)-N-(5-(propylthio)-3-((1R,2S,3S,4R)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous Amide

  • Catalogue No.:PA 47 0111114

  • CAS :

    NA

  • Molecular Formula : C21H23F2N7O4S

  • Molecular Weight : 507.52

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Details 
stdClass Object
(
    [pname] => Benzyl ((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)carbamate
    [catalogue_number] => PA 47 0111115
    [category_ids] => ,70,71,75,78,79,82,162,
    [chemical_name] => 
    [weight] => 267.28
    [form] => C13H17NO5
    [cas] => NA
    [pslug] => benzyl-1r-2s-3r-4s-2-3-4-trihydroxycyclopentyl-carbamate-pa470111115
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PA 47 0111115

Benzyl ((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)carbamate

  • Catalogue No.:PA 47 0111115

  • CAS :

    NA

  • Molecular Formula : C13H17NO5

  • Molecular Weight : 267.28

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Details 
stdClass Object
(
    [pname] => (1S,2S,3R,5S)-3-(7-((3-(3,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 0111117
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 551.57
    [form] => C23H27F2N7O5S
    [cas] => NA
    [pslug] => 1s-2s-3r-5s-3-7-3-3-4-difluorophenyl-4-5-dihydroisoxazol-5-yl-amino-5-propylthio-3h-1-2-3-triazolo-4-5-d-pyrimidin-3-yl-5-2-hydroxyethoxy-cyclopentane-1-2-diol-pa470111117
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PA 47 0111117

(1S,2S,3R,5S)-3-(7-((3-(3,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

  • Catalogue No.:PA 47 0111117

  • CAS :

    NA

  • Molecular Formula : C23H27F2N7O5S

  • Molecular Weight : 551.57

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2,6-Difluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111140
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => 1643378-55-5
    [pslug] => 1643378-55-5-1r-2s-2-2-6-difluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111140
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PA 47 0111140

(1R,2S)-2-(2,6-Difluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111140

  • CAS :

    1643378-55-5

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2-Fluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111141
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 187.64
    [form] => C9H11ClFN
    [cas] => 1643378-57-7
    [pslug] => 1643378-57-7-1r-2s-2-2-fluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111141
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PA 47 0111141

(1R,2S)-2-(2-Fluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111141

  • CAS :

    1643378-57-7

  • Molecular Formula : C9H11ClFN

  • Molecular Weight : 187.64

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2,5-Difluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111142
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => 1643378-54-4
    [pslug] => 1643378-54-4-1r-2s-2-2-5-difluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111142
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PA 47 0111142

(1R,2S)-2-(2,5-Difluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111142

  • CAS :

    1643378-54-4

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2,4-Difluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111143
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => 1643378-53-3
    [pslug] => 1643378-53-3-1r-2s-2-2-4-difluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111143
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PA 47 0111143

(1R,2S)-2-(2,4-Difluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111143

  • CAS :

    1643378-53-3

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

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CPHI INDIA- 28, 30 November