ticagrelor

Impurities - A P2Y12 receptor antagonist drug, used as a platelet aggregation inhibitor. Ticagrelor is a nucleoside analogue used in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases. Reference standards of Ticagrelor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => rel-2-(3-Ethoxy-4-fluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111104
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 231.7
    [form] => C11H15ClFNO
    [cas] => 2055841-10-4
    [pslug] => 2055841-10-4-rel-2-3-ethoxy-4-fluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111104
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PA 47 0111104
PA 47 0111104

rel-2-(3-Ethoxy-4-fluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111104

  • CAS :

    2055841-10-4

  • Molecular Formula : C11H15ClFNO

  • Molecular Weight : 231.7

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Details 
stdClass Object
(
    [pname] => 2-(((3aR,4S,6R,6aS)-6-(7-Chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
    [catalogue_number] => PA 47 0111105
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 429.92
    [form] => C17H24ClN5O4S
    [cas] => 376608-75-2
    [pslug] => 376608-75-2-2-3ar-4s-6r-6as-6-7-chloro-5-propylthio-3h-1-2-3-triazolo-4-5-d-pyrimidin-3-yl-2-2-dimethyltetrahydro-4h-cyclopenta-d-1-3-dioxol-4-yl-oxy-ethan-1-ol-pa470111105
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PA 47 0111105
PA 47 0111105

2-(((3aR,4S,6R,6aS)-6-(7-Chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

  • Catalogue No.:PA 47 0111105

  • CAS :

    376608-75-2

  • Molecular Formula : C17H24ClN5O4S

  • Molecular Weight : 429.92

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Details 
stdClass Object
(
    [pname] => N-(5-Amino-6-chloro-2-(propylsulfinyl)pyrimidin-4-yl)-N-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)nitrous amide
    [catalogue_number] => PA 47 0111107
    [category_ids] => ,75,76,78,70,82,162,
    [chemical_name] => 
    [weight] => 423.87
    [form] => C14H22ClN5O6S
    [cas] => NA
    [pslug] => n-5-amino-6-chloro-2-propylsulfinyl-pyrimidin-4-yl-n-1r-2s-3s-4s-2-3-dihydroxy-4-2-hydroxyethoxy-cyclopentyl-nitrous-amide-pa470111107
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PA 47 0111107
PA 47 0111107

N-(5-Amino-6-chloro-2-(propylsulfinyl)pyrimidin-4-yl)-N-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)nitrous amide

  • Catalogue No.:PA 47 0111107

  • CAS :

    NA

  • Molecular Formula : C14H22ClN5O6S

  • Molecular Weight : 423.87

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Details 
stdClass Object
(
    [pname] => N-(2-(3,4-Difluorophenyl)cyclopropyl)-N-(5-(propylthio)-3-((1R,2S,3S,4R)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous Amide
    [catalogue_number] => PA 47 0111114
    [category_ids] => ,70,71,75,78,79,82,162,
    [chemical_name] => 
    [weight] => 507.52
    [form] => C21H23F2N7O4S
    [cas] => NA
    [pslug] => n-2-3-4-difluorophenyl-cyclopropyl-n-5-propylthio-3-1r-2s-3s-4r-2-3-4-trihydroxycyclopentyl-3h-1-2-3-triazolo-4-5-d-pyrimidin-7-yl-nitrous-amide-pa470111114
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PA 47 0111114
PA 47 0111114

N-(2-(3,4-Difluorophenyl)cyclopropyl)-N-(5-(propylthio)-3-((1R,2S,3S,4R)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous Amide

  • Catalogue No.:PA 47 0111114

  • CAS :

    NA

  • Molecular Formula : C21H23F2N7O4S

  • Molecular Weight : 507.52

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Details 
stdClass Object
(
    [pname] => Benzyl ((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)carbamate
    [catalogue_number] => PA 47 0111115
    [category_ids] => ,70,71,75,78,79,82,162,
    [chemical_name] => 
    [weight] => 267.28
    [form] => C13H17NO5
    [cas] => NA
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PA 47 0111115
PA 47 0111115

Benzyl ((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)carbamate

  • Catalogue No.:PA 47 0111115

  • CAS :

    NA

  • Molecular Formula : C13H17NO5

  • Molecular Weight : 267.28

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Details 
stdClass Object
(
    [pname] => (1S,2S,3R,5S)-3-(7-((3-(3,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 0111117
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 551.57
    [form] => C23H27F2N7O5S
    [cas] => NA
    [pslug] => 1s-2s-3r-5s-3-7-3-3-4-difluorophenyl-4-5-dihydroisoxazol-5-yl-amino-5-propylthio-3h-1-2-3-triazolo-4-5-d-pyrimidin-3-yl-5-2-hydroxyethoxy-cyclopentane-1-2-diol-pa470111117
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PA 47 0111117
PA 47 0111117

(1S,2S,3R,5S)-3-(7-((3-(3,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

  • Catalogue No.:PA 47 0111117

  • CAS :

    NA

  • Molecular Formula : C23H27F2N7O5S

  • Molecular Weight : 551.57

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2,6-Difluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111140
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => 1643378-55-5
    [pslug] => 1643378-55-5-1r-2s-2-2-6-difluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111140
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PA 47 0111140
PA 47 0111140

(1R,2S)-2-(2,6-Difluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111140

  • CAS :

    1643378-55-5

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2-Fluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111141
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 187.64
    [form] => C9H11ClFN
    [cas] => 1643378-57-7
    [pslug] => 1643378-57-7-1r-2s-2-2-fluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111141
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PA 47 0111141
PA 47 0111141

(1R,2S)-2-(2-Fluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111141

  • CAS :

    1643378-57-7

  • Molecular Formula : C9H11ClFN

  • Molecular Weight : 187.64

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2,5-Difluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111142
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => 1643378-54-4
    [pslug] => 1643378-54-4-1r-2s-2-2-5-difluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111142
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PA 47 0111142
PA 47 0111142

(1R,2S)-2-(2,5-Difluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111142

  • CAS :

    1643378-54-4

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

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Details 
stdClass Object
(
    [pname] => (1R,2S)-2-(2,4-Difluorophenyl)cyclopropan-1-amine Hydrochloride
    [catalogue_number] => PA 47 0111143
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => 1643378-53-3
    [pslug] => 1643378-53-3-1r-2s-2-2-4-difluorophenyl-cyclopropan-1-amine-hydrochloride-pa470111143
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PA 47 0111143
PA 47 0111143

(1R,2S)-2-(2,4-Difluorophenyl)cyclopropan-1-amine Hydrochloride

  • Catalogue No.:PA 47 0111143

  • CAS :

    1643378-53-3

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

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Details
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