tofacitinib citrate

Impurities - A janus kinase (JAK) inhibitor class of drug used for the treatment of rheumatoid arthritis (RA)Reference standards of Tofacitinib Citrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => N,​4-​Dimethyl-​1-​benzyl​-3-​piperidinamine
    [catalogue_number] => PA 47 13570
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 218.34
    [form] => C14H22N2
    [cas] => 384338-23-2
    [pslug] => 384338-23-2-n-​4-​dimethyl-​1-​benzyl​-3-​piperidinamine-pa4713570
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PA 47 13570
PA 47 13570

N,​4-​Dimethyl-​1-​benzyl​-3-​piperidinamine


  • Catalogue No.:PA 47 13570

  • CAS :

    384338-23-2

  • Molecular Formula : C14H22N2

  • Molecular Weight : 218.34

stdClass Object
(
    [pname] => (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
    [catalogue_number] => PA 47 13580
    [category_ids] => ,85,83,82,78,75,71,70,80,
    [chemical_name] => 
    [weight] => 291.26
    [form] => C14H24Cl2N2
    [cas] => 1821769-41-8
    [pslug] => 1821769-41-8-3s-4r-1-benzyl-n-4-dimethylpiperidin-3-amine-dihydrochloride-pa4713580
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PA 47 13580
PA 47 13580

(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride


  • Catalogue No.:PA 47 13580

  • CAS :

    1821769-41-8

  • Molecular Formula : C14H24Cl2N2

  • Molecular Weight : 291.26

stdClass Object
(
    [pname] => (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
    [catalogue_number] => PA 47 13590
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 291.26
    [form] => C14H24Cl2N2
    [cas] => NA
    [pslug] => 3r-4s-1-benzyl-n-4-dimethylpiperidin-3-amine-dihydrochloride-pa4713590
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PA 47 13590
PA 47 13590

(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride


  • Catalogue No.:PA 47 13590

  • CAS :

    NA

  • Molecular Formula : C14H24Cl2N2

  • Molecular Weight : 291.26

stdClass Object
(
    [pname] => 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid
    [catalogue_number] => PA 47 13600
    [category_ids] => ,85,83,82,80,78,75,71,70,
    [chemical_name] => 
    [weight] => 331.37
    [form] => C16H21N5O3
    [cas] => 2328165-36-0
    [pslug] => 2328165-36-0-3-3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-3-oxopropanoic-acid-pa4713600
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PA 47 13600
PA 47 13600

3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid


  • Catalogue No.:PA 47 13600

  • CAS :

    2328165-36-0

  • Molecular Formula : C16H21N5O3

  • Molecular Weight : 331.37

stdClass Object
(
    [pname] => 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide
    [catalogue_number] => PA 47 13610
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 330.38
    [form] => C16H22N6O2
    [cas] => 1675248-19-7
    [pslug] => 1675248-19-7-3-3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-3-oxopropanamide-pa4713610
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PA 47 13610
PA 47 13610

3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide


  • Catalogue No.:PA 47 13610

  • CAS :

    1675248-19-7

  • Molecular Formula : C16H22N6O2

  • Molecular Weight : 330.38

stdClass Object
(
    [pname] => N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 47 13630
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 245.32
    [form] => C13H19N5
    [cas] => 1260614-73-0
    [pslug] => 1260614-73-0-n-methyl-n-3s-4s-4-methylpiperidin-3-yl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa4713630
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PA 47 13630
PA 47 13630

N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 47 13630

  • CAS :

    1260614-73-0

  • Molecular Formula : C13H19N5

  • Molecular Weight : 245.32

stdClass Object
(
    [pname] => Des-(N-oxopropanenitrile)-N-methylbenzyl
    [catalogue_number] => PA 47 13640
    [category_ids] => ,85,83,80,71,70,75,78,82,
    [chemical_name] => 
    [weight] => 335.45
    [form] => C20H25N5
    [cas] => 477600-73-0
    [pslug] => 477600-73-0-des-n-oxopropanenitrile-n-methylbenzyl-pa4713640
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PA 47 13640
PA 47 13640

Des-(N-oxopropanenitrile)-N-methylbenzyl


  • Catalogue No.:PA 47 13640

  • CAS :

    477600-73-0

  • Molecular Formula : C20H25N5

  • Molecular Weight : 335.45

stdClass Object
(
    [pname] => 3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
    [catalogue_number] => PA 47 13850
    [category_ids] => ,97,82,80,79,78,76,75,71,70,
    [chemical_name] => 
    [weight] => 346.82
    [form] => C16H19ClN6O
    [cas] => 1616761-00-2
    [pslug] => 1616761-00-2-3-3r-4r-3-2-chloro-7h-pyrrolo-2-3-d-pyrimidin-4-yl-methyl-amino-4-methylpiperidin-1-yl-3-oxopropanenitrile-pa4713850
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PA 47 13850
PA 47 13850

3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile


  • Catalogue No.:PA 47 13850

  • CAS :

    1616761-00-2

  • Molecular Formula : C16H19ClN6O

  • Molecular Weight : 346.82

stdClass Object
(
    [pname] => (3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide
    [catalogue_number] => PA 47 13860
    [category_ids] => ,79,97,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 261.33
    [form] => C13H19N5O
    [cas] => NA
    [pslug] => 3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidine-1-oxide-pa4713860
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PA 47 13860
PA 47 13860

(3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide


  • Catalogue No.:PA 47 13860

  • CAS :

    NA

  • Molecular Formula : C13H19N5O

  • Molecular Weight : 261.33

stdClass Object
(
    [pname] => N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 47 0131000
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 489.64
    [form] => C27H31N5O2S
    [cas] => 923036-30-0
    [pslug] => 923036-30-0-n-3r-4r-1-benzyl-4-methylpiperidin-3-yl-n-methyl-7-tosyl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa470131000
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PA 47 0131000
PA 47 0131000

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 47 0131000

  • CAS :

    923036-30-0

  • Molecular Formula : C27H31N5O2S

  • Molecular Weight : 489.64

stdClass Object
(
    [pname] => N-((3R,4R)-1-Ethyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 47 0131001
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 273.38
    [form] => C15H23N5
    [cas] => 2183519-70-0
    [pslug] => 2183519-70-0-n-3r-4r-1-ethyl-4-methylpiperidin-3-yl-n-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa470131001
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PA 47 0131001
PA 47 0131001

N-((3R,4R)-1-Ethyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 47 0131001

  • CAS :

    2183519-70-0

  • Molecular Formula : C15H23N5

  • Molecular Weight : 273.38

stdClass Object
(
    [pname] => Butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate
    [catalogue_number] => PA 47 0131002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 387.48
    [form] => C20H29N5O3
    [cas] => 2227199-31-5
    [pslug] => 2227199-31-5-butyl-3-3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-3-oxopropanoate-pa470131002
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PA 47 0131002
PA 47 0131002

Butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate


  • Catalogue No.:PA 47 0131002

  • CAS :

    2227199-31-5

  • Molecular Formula : C20H29N5O3

  • Molecular Weight : 387.48

stdClass Object
(
    [pname] => 3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile
    [catalogue_number] => PA 47 0131003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 379.42
    [form] => C19H21N7O2
    [cas] => 2459302-77-1
    [pslug] => 2459302-77-1-3-4-3r-4r-1-2-cyanoacetyl-4-methylpiperidin-3-yl-methyl-amino-7h-pyrrolo-2-3-d-pyrimidin-7-yl-3-oxopropanenitrile-pa470131003
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PA 47 0131003
PA 47 0131003

3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile


  • Catalogue No.:PA 47 0131003

  • CAS :

    2459302-77-1

  • Molecular Formula : C19H21N7O2

  • Molecular Weight : 379.42

stdClass Object
(
    [pname] => 4'-Chloro-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine
    [catalogue_number] => PA 47 0131004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 270.68
    [form] => C12H7ClN6
    [cas] => 134965-85-8
    [pslug] => 134965-85-8-4-chloro-4-7-bi-7h-pyrrolo-2-3-d-pyrimidine-pa470131004
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PA 47 0131004
PA 47 0131004

4'-Chloro-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine


  • Catalogue No.:PA 47 0131004

  • CAS :

    134965-85-8

  • Molecular Formula : C12H7ClN6

  • Molecular Weight : 270.68

stdClass Object
(
    [pname] => 1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one
    [catalogue_number] => PA 47 0131005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 287.37
    [form] => C15H21N5O
    [cas] => 477600-76-3
    [pslug] => 477600-76-3-1-3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-ethan-1-one-pa470131005
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PA 47 0131005
PA 47 0131005

1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one


  • Catalogue No.:PA 47 0131005

  • CAS :

    477600-76-3

  • Molecular Formula : C15H21N5O

  • Molecular Weight : 287.37

stdClass Object
(
    [pname] => Ethyl 4-cyano-5-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-imino-5-oxopentanoate
    [catalogue_number] => PAI 47 013001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 427.51
    [form] => C21H29N7O3
    [cas] => NA
    [pslug] => ethyl-4-cyano-5-3r-4r-3-6-7-dihydro-5h-pyrrolo-2-3-d-pyrimidin-4-yl-methyl-amino-4-methylpiperidin-1-yl-3-imino-5-oxopentanoate-pai47013001
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PAI 47 013001
PAI 47 013001

Ethyl 4-cyano-5-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-imino-5-oxopentanoate


  • Catalogue No.:PAI 47 013001

  • CAS :

    NA

  • Molecular Formula : C21H29N7O3

  • Molecular Weight : 427.51

stdClass Object
(
    [pname] => Tofacitinib Citrate (IPRST025)
    [catalogue_number] => PA IPRST025
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
    [pslug] => tofacitinib-citrate-iprst025-paiprst025
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PA IPRST025
PA IPRST025

Tofacitinib Citrate (IPRST025)


  • Catalogue No.:PA IPRST025

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine
    [catalogue_number] => PA 47 0131008
    [category_ids] => ,82,78,75,71,70,80,
    [chemical_name] => 
    [weight] => 218.34
    [form] => C14H22N2
    [cas] => 1638499-33-8
    [pslug] => 1638499-33-8-3s-4r-1-benzyl-n-4-dimethylpiperidin-3-amine-pa470131008
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PA 47 0131008
PA 47 0131008

(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine


  • Catalogue No.:PA 47 0131008

  • CAS :

    1638499-33-8

  • Molecular Formula : C14H22N2

  • Molecular Weight : 218.34

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