Tofacitinib Citrate-impurities | Pharmaffiliates

tofacitinib citrate

A janus kinase (JAK) inhibitor class of drug used for the treatment of rheumatoid arthritis (RA)Reference standards of Tofacitinib Citrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => N,​4-​Dimethyl-​1-​benzyl​-3-​piperidinamine
    [catalogue_number] => PA 47 13570
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 218.34
    [form] => C14H22N2
    [cas] => 384338-23-2
    [pslug] => 384338-23-2-n-​4-​dimethyl-​1-​benzyl​-3-​piperidinamine-pa4713570
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PA 47 13570

N,​4-​Dimethyl-​1-​benzyl​-3-​piperidinamine


  • Catalogue No.:PA 47 13570

  • CAS :

    384338-23-2

  • Molecular Formula : C14H22N2

  • Molecular Weight : 218.34

stdClass Object
(
    [pname] => (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
    [catalogue_number] => PA 47 13580
    [category_ids] => 85,83,82,78,75,71,70,80
    [chemical_name] => 
    [weight] => 291.26
    [form] => C14H24Cl2N2
    [cas] => 1821769-41-8
    [pslug] => 1821769-41-8-3s-4r-1-benzyl-n-4-dimethylpiperidin-3-amine-dihydrochloride-pa4713580
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PA 47 13580

(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride


  • Catalogue No.:PA 47 13580

  • CAS :

    1821769-41-8

  • Molecular Formula : C14H24Cl2N2

  • Molecular Weight : 291.26

stdClass Object
(
    [pname] => (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
    [catalogue_number] => PA 47 13590
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 291.26
    [form] => C14H24Cl2N2
    [cas] => NA
    [pslug] => 3r-4s-1-benzyl-n-4-dimethylpiperidin-3-amine-dihydrochloride-pa4713590
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PA 47 13590

(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride


  • Catalogue No.:PA 47 13590

  • CAS :

    NA

  • Molecular Formula : C14H24Cl2N2

  • Molecular Weight : 291.26

stdClass Object
(
    [pname] => 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid
    [catalogue_number] => PA 47 13600
    [category_ids] => 85,83,82,80,78,75,71,70
    [chemical_name] => 
    [weight] => 331.37
    [form] => C16H21N5O3
    [cas] => 2328165-36-0
    [pslug] => 2328165-36-0-3-3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-3-oxopropanoic-acid-pa4713600
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PA 47 13600

3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid


  • Catalogue No.:PA 47 13600

  • CAS :

    2328165-36-0

  • Molecular Formula : C16H21N5O3

  • Molecular Weight : 331.37

stdClass Object
(
    [pname] => 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide
    [catalogue_number] => PA 47 13610
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 330.38
    [form] => C16H22N6O2
    [cas] => 1675248-19-7
    [pslug] => 1675248-19-7-3-3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-3-oxopropanamide-pa4713610
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PA 47 13610

3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide


  • Catalogue No.:PA 47 13610

  • CAS :

    1675248-19-7

  • Molecular Formula : C16H22N6O2

  • Molecular Weight : 330.38

stdClass Object
(
    [pname] => N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 47 13630
    [category_ids] => ,80,71,75,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 245.32
    [form] => C13H19N5
    [cas] => 1260614-73-0
    [pslug] => 1260614-73-0-n-methyl-n-3s-4s-4-methylpiperidin-3-yl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa4713630
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PA 47 13630

N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 47 13630

  • CAS :

    1260614-73-0

  • Molecular Formula : C13H19N5

  • Molecular Weight : 245.32

stdClass Object
(
    [pname] => Des-(N-oxopropanenitrile)-N-methylbenzyl
    [catalogue_number] => PA 47 13640
    [category_ids] => 85,83,80,71,70,75,78,82
    [chemical_name] => 
    [weight] => 335.45
    [form] => C20H25N5
    [cas] => 477600-73-0
    [pslug] => 477600-73-0-des-n-oxopropanenitrile-n-methylbenzyl-pa4713640
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PA 47 13640

Des-(N-oxopropanenitrile)-N-methylbenzyl


  • Catalogue No.:PA 47 13640

  • CAS :

    477600-73-0

  • Molecular Formula : C20H25N5

  • Molecular Weight : 335.45

stdClass Object
(
    [pname] => 3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
    [catalogue_number] => PA 47 13850
    [category_ids] => ,79,97,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 346.82
    [form] => C16H19ClN6O
    [cas] => 1616761-00-2
    [pslug] => 1616761-00-2-3-3r-4r-3-2-chloro-7h-pyrrolo-2-3-d-pyrimidin-4-yl-methyl-amino-4-methylpiperidin-1-yl-3-oxopropanenitrile-pa4713850
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PA 47 13850

3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile


  • Catalogue No.:PA 47 13850

  • CAS :

    1616761-00-2

  • Molecular Formula : C16H19ClN6O

  • Molecular Weight : 346.82

stdClass Object
(
    [pname] => (3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide
    [catalogue_number] => PA 47 13860
    [category_ids] => ,79,97,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 261.33
    [form] => C13H19N5O
    [cas] => NA
    [pslug] => 3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidine-1-oxide-pa4713860
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PA 47 13860

(3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide


  • Catalogue No.:PA 47 13860

  • CAS :

    NA

  • Molecular Formula : C13H19N5O

  • Molecular Weight : 261.33

stdClass Object
(
    [pname] => N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 47 0131000
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 489.64
    [form] => C27H31N5O2S
    [cas] => 923036-30-0
    [pslug] => 923036-30-0-n-3r-4r-1-benzyl-4-methylpiperidin-3-yl-n-methyl-7-tosyl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa470131000
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PA 47 0131000

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 47 0131000

  • CAS :

    923036-30-0

  • Molecular Formula : C27H31N5O2S

  • Molecular Weight : 489.64

stdClass Object
(
    [pname] => N-((3R,4R)-1-Ethyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 47 0131001
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 273.38
    [form] => C15H23N5
    [cas] => NA
    [pslug] => -n-3r-4r-1-ethyl-4-methylpiperidin-3-yl-n-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa470131001
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PA 47 0131001

N-((3R,4R)-1-Ethyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 47 0131001

  • CAS :

    NA

  • Molecular Formula : C15H23N5

  • Molecular Weight : 273.38

stdClass Object
(
    [pname] => Butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate
    [catalogue_number] => PA 47 0131002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 387.48
    [form] => C20H29N5O3
    [cas] => 2227199-31-5
    [pslug] => 2227199-31-5-butyl-3-3r-4r-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-3-oxopropanoate-pa470131002
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PA 47 0131002

Butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate


  • Catalogue No.:PA 47 0131002

  • CAS :

    2227199-31-5

  • Molecular Formula : C20H29N5O3

  • Molecular Weight : 387.48

stdClass Object
(
    [pname] => 3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile
    [catalogue_number] => PA 47 0131003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 379.42
    [form] => C19H21N7O2
    [cas] => NA
    [pslug] => 3-4-3r-4r-1-2-cyanoacetyl-4-methylpiperidin-3-yl-methyl-amino-7h-pyrrolo-2-3-d-pyrimidin-7-yl-3-oxopropanenitrile-pa470131003
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PA 47 0131003

3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile


  • Catalogue No.:PA 47 0131003

  • CAS :

    NA

  • Molecular Formula : C19H21N7O2

  • Molecular Weight : 379.42

stdClass Object
(
    [pname] => 4'-Chloro-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine
    [catalogue_number] => PA 47 0131004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 270.68
    [form] => C12H7ClN6
    [cas] => 134965-85-8
    [pslug] => 134965-85-8-4-chloro-4-7-bi-7h-pyrrolo-2-3-d-pyrimidine-pa470131004
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PA 47 0131004

4'-Chloro-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine


  • Catalogue No.:PA 47 0131004

  • CAS :

    134965-85-8

  • Molecular Formula : C12H7ClN6

  • Molecular Weight : 270.68

stdClass Object
(
    [pname] => 1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one
    [catalogue_number] => PA 47 0131005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 287.37
    [form] => C15H21N5O
    [cas] => NA
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PA 47 0131005

1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one


  • Catalogue No.:PA 47 0131005

  • CAS :

    NA

  • Molecular Formula : C15H21N5O

  • Molecular Weight : 287.37

stdClass Object
(
    [pname] => Ethyl 4-cyano-5-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-imino-5-oxopentanoate
    [catalogue_number] => PAI 47 013001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 427.51
    [form] => C21H29N7O3
    [cas] => NA
    [pslug] => ethyl-4-cyano-5-3r-4r-3-6-7-dihydro-5h-pyrrolo-2-3-d-pyrimidin-4-yl-methyl-amino-4-methylpiperidin-1-yl-3-imino-5-oxopentanoate-pai47013001
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PAI 47 013001

Ethyl 4-cyano-5-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-imino-5-oxopentanoate


  • Catalogue No.:PAI 47 013001

  • CAS :

    NA

  • Molecular Formula : C21H29N7O3

  • Molecular Weight : 427.51

stdClass Object
(
    [pname] => Tofacitinib Citrate (IPRST025)
    [catalogue_number] => PA IPRST025
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
    [pslug] => tofacitinib-citrate-iprst025-paiprst025
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Tofacitinib Citrate (IPRST025)


  • Catalogue No.:PA IPRST025

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA