vildagliptin
Vildagliptin is used in combination to treat Diabetes Mellitus Type 2. Vildagliptin is an oral anti-hyperglycemic agent. Reference standards of Vildagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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(2S)-1-(2-((3,5-Dihydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile
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[catalogue_number] => PA 22 17540
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[chemical_name] =>
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[form] => C24H33N5O3
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(2S,2'S)-1,1'-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrrolidinecarbonitrile
Catalogue No.:PA 22 17540
Molecular Formula : C24H33N5O3
Molecular Weight : 439.55
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[catalogue_number] => PA 22 17550
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[form] => C17H27N3O3
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N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-D-prolinamide
Catalogue No.:PA 22 17550
Molecular Formula : C17H27N3O3
Molecular Weight : 321.41
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(R)-1-[2-(3-Hydroxyadamantan-1-ylamino)acetyl]pyrrolidine-2-carbonitrile
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[pname] => Vildagliptin Chloroacetyl Amide Impurity
[catalogue_number] => PA 22 17570
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[chemical_name] =>
[weight] => 190.63
[form] => C7H11ClN2O2
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Vildagliptin Chloroacetyl Amide Impurity
Catalogue No.:PA 22 17570
Molecular Formula : C7H11ClN2O2
Molecular Weight : 190.63
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[catalogue_number] => PA 22 17580
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Vildagliptin Cyclic Amidine
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[pname] => 2-(3-Hydroxy adamantan-1-yl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione
[catalogue_number] => PA 22 17590
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[weight] => 304.38
[form] => C17H24N2O3
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2-(3-Hydroxy adamantan-1-yl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione
Catalogue No.:PA 22 17590
Molecular Formula : C17H24N2O3
Molecular Weight : 304.38
stdClass Object
(
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[form] => C17H23N3O2
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(S)-1-((E)-2-(((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)imino)acetyl)pyrrolidine-2-carbonitrile
Catalogue No.:PA 22 17600
Molecular Formula : C17H23N3O2
Molecular Weight : 301.38
stdClass Object
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[pname] => Vildagliptin Chloroacetyl Nitrile (R)-Isomer
[catalogue_number] => PA 22 17610
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[weight] => 172.61
[form] => C7H9ClN2O
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Vildagliptin Chloroacetyl Nitrile (R)-Isomer
Catalogue No.:PA 22 17610
Molecular Formula : C7H9ClN2O
Molecular Weight : 172.61
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[catalogue_number] => PA 22 17620
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[weight] => 172.61
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Vildagliptin Chloroacetyl Nitrile (S)-Isomer
Catalogue No.:PA 22 17620
Molecular Formula : C7H9ClN2O
Molecular Weight : 172.61
stdClass Object
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[pname] => 1-(5-((l2-Azanyl)carbonyl)-2,3-dihydro-1H-pyrrol-1-yl)-2-((3-hydroxyadamantan-1-yl)amino)ethan-1-one
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[weight] => 318.4
[form] => C17H24N3O3
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1-(5-((l2-Azanyl)carbonyl)-2,3-dihydro-1H-pyrrol-1-yl)-2-((3-hydroxyadamantan-1-yl)amino)ethan-1-one
stdClass Object
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[pname] => Vildagliptin β-D-Glucuronide
[catalogue_number] => PA 22 17760
[category_ids] => ,69,70,75,76,78,82,95,
[chemical_name] =>
[weight] => 479.52
[form] => C23H33N3O8
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Vildagliptin β-D-Glucuronide
Catalogue No.:PA 22 17760
Molecular Formula : C23H33N3O8
Molecular Weight : 479.52
stdClass Object
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[catalogue_number] => PA 22 17800
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[chemical_name] =>
[weight] => 303.41
[form] => C17H25N3O2
[cas] => 1710765-32-4
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(S)-2-((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)-1-iminohexahydropyrrolo[1,2-a]pyrazin-4(1H)-one
Catalogue No.:PA 22 17800
Molecular Formula : C17H25N3O2
Molecular Weight : 303.41
stdClass Object
(
[pname] => Methyl (2-chloroacetyl)-L-prolinate
[catalogue_number] => PA 22 0171001
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[chemical_name] =>
[weight] => 205.64
[form] => C8H12ClNO3
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Methyl (2-chloroacetyl)-L-prolinate
Catalogue No.:PA 22 0171001
Molecular Formula : C8H12ClNO3
Molecular Weight : 205.64
stdClass Object
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[pname] => Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
[catalogue_number] => PA 22 0171002
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[weight] => 194.23
[form] => C10H14N2O2
[cas] => 6708-06-1
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Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
Catalogue No.:PA 22 0171002
Molecular Formula : C10H14N2O2
Molecular Weight : 194.23
stdClass Object
(
[pname] => (R)-Tetrahydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,4(3H)-dione
[catalogue_number] => PA 22 0171003
[category_ids] => ,75,76,70,78,82,
[chemical_name] =>
[weight] => 155.15
[form] => C7H9NO3
[cas] => NA
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(R)-Tetrahydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,4(3H)-dione
Catalogue No.:PA 22 0171003
Molecular Formula : C7H9NO3
Molecular Weight : 155.15
stdClass Object
(
[pname] => (2-Hydroxyacetyl)-L-proline
[catalogue_number] => PAI 22 017001
[category_ids] => ,82,78,76,75,70,
[chemical_name] =>
[weight] => 173.17
[form] => C7H11NO4
[cas] => 172723-43-2
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(2-Hydroxyacetyl)-L-proline
Catalogue No.:PAI 22 017001
Molecular Formula : C7H11NO4
Molecular Weight : 173.17
stdClass Object
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[pname] => (1s,3s,5R,7S)-6-Aminoadamantane-1,3-diol
[catalogue_number] => PA 22 0171006
[category_ids] => ,123,81,78,75,76,82,
[chemical_name] =>
[weight] => 183.25
[form] => C10H17NO2
[cas] => 918830-94-1
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(1s,3s,5R,7S)-6-Aminoadamantane-1,3-diol
Catalogue No.:PA 22 0171006
Molecular Formula : C10H17NO2
Molecular Weight : 183.25
stdClass Object
(
[pname] => 1,3-Adamantanediamine
[catalogue_number] => PA 22 0171007
[category_ids] => ,123,81,78,75,76,82,
[chemical_name] =>
[weight] => 166.27
[form] => C10H18N2
[cas] => 10303-95-4
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Catalogue No.:PA 22 0171007
Molecular Formula : C10H18N2
Molecular Weight : 166.27
stdClass Object
(
[pname] => Adamantane-1,3,5,7-tetraol
[catalogue_number] => PA 22 0171008
[category_ids] => ,78,75,76,82,
[chemical_name] =>
[weight] => 200.23
[form] => C10H16O4
[cas] => 16104-28-2
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Adamantane-1,3,5,7-tetraol
Catalogue No.:PA 22 0171008
Molecular Formula : C10H16O4
Molecular Weight : 200.23
stdClass Object
(
[pname] => (3s,5s,7s)-3,5,7-Trinitroadamantan-1-amine
[catalogue_number] => PA 22 0171009
[category_ids] => ,78,75,76,82,
[chemical_name] =>
[weight] => 286.24
[form] => C10H14N4O6
[cas] => 119694-48-3
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(3s,5s,7s)-3,5,7-Trinitroadamantan-1-amine
Catalogue No.:PA 22 0171009
Molecular Formula : C10H14N4O6
Molecular Weight : 286.24
stdClass Object
(
[pname] => 1,3,5,7-Tetranitroadamantane
[catalogue_number] => PA 22 0171010
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[chemical_name] =>
[weight] => 316.23
[form] => C10H12N4O8
[cas] => 75476-36-7
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1,3,5,7-Tetranitroadamantane
Catalogue No.:PA 22 0171010
Molecular Formula : C10H12N4O8
Molecular Weight : 316.23
stdClass Object
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[pname] => (1r,3R,5S,7r)-3,5-Dinitroadamantan-1-amine
[catalogue_number] => PA 22 0171011
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[chemical_name] =>
[weight] => 241.25
[form] => C10H15N3O4
[cas] => NA
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(1r,3R,5S,7r)-3,5-Dinitroadamantan-1-amine
Catalogue No.:PA 22 0171011
Molecular Formula : C10H15N3O4
Molecular Weight : 241.25
stdClass Object
(
[pname] => (1s,3r,5R,7S)-3-Aminoadamantan-1-yl nitrate
[catalogue_number] => PA 22 0171013
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[chemical_name] =>
[weight] => 212.25
[form] => C10H16N2O3
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(1s,3r,5R,7S)-3-Aminoadamantan-1-yl nitrate
Catalogue No.:PA 22 0171013
Molecular Formula : C10H16N2O3
Molecular Weight : 212.25
stdClass Object
(
[pname] => N-Boc-L-proline
[catalogue_number] => PAI 22 017002
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[chemical_name] =>
[weight] => 215.25
[form] => C10H17NO4
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Catalogue No.:PAI 22 017002
Molecular Formula : C10H17NO4
Molecular Weight : 215.25
stdClass Object
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[catalogue_number] => PAI 22 017003
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[weight] => 214.27
[form] => C10H18N2O3
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Catalogue No.:PAI 22 017003
Molecular Formula : C10H18N2O3
Molecular Weight : 214.27
stdClass Object
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[weight] => 228.17
[form] => C7H11F3N2O3
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(S)-Pyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
Catalogue No.:PAI 22 017004
Molecular Formula : C7H11F3N2O3
Molecular Weight : 228.17
stdClass Object
(
[pname] => (S)-2-(2-Carbamoylpyrrolidin-1-yl)-2-oxoethyl Acetate
[catalogue_number] => PAI 22 017005
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[chemical_name] =>
[weight] => 214.22
[form] => C9H14N2O4
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(S)-2-(2-Carbamoylpyrrolidin-1-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 22 017005
Molecular Formula : C9H14N2O4
Molecular Weight : 214.22
stdClass Object
(
[pname] => Vildagliptin N-Oxide
[catalogue_number] => PA 22 0171014
[category_ids] => ,75,76,78,70,82,
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[weight] => 319.41
[form] => C17H25N3O3
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Catalogue No.:PA 22 0171014
Molecular Formula : C17H25N3O3
Molecular Weight : 319.41
stdClass Object
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[catalogue_number] => PA 22 0171015
[category_ids] => 76,82,78,75,70
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[weight] => 287.41
[form] => C17H25N3O
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Catalogue No.:PA 22 0171015
Molecular Formula : C17H25N3O
Molecular Weight : 287.41
stdClass Object
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[catalogue_number] => PA 22 0171016
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[weight] => 225.07
[form] => C7H10Cl2N2O2
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(2S)-1-(Dichloroacetyl)pyrrolidine-2-carboxamide
Catalogue No.:PA 22 0171016
Molecular Formula : C7H10Cl2N2O2
Molecular Weight : 225.07
stdClass Object
(
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[catalogue_number] => PA 22 0171017
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[weight] => 172.61
[form] => C7H9ClN2O
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1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
Catalogue No.:PA 22 0171017
Molecular Formula : C7H9ClN2O
Molecular Weight : 172.61
stdClass Object
(
[pname] => (R)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide
[catalogue_number] => PA 22 0171018
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[weight] => 190.63
[form] => C7H11ClN2O2
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(R)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide
Catalogue No.:PA 22 0171018
Molecular Formula : C7H11ClN2O2
Molecular Weight : 190.63
stdClass Object
(
[pname] => (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidine carboxylic acid lithium salt
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[weight] => 328.34
[form] => C17H25LiN2O4
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(2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidine carboxylic acid lithium salt
Catalogue No.:PA 22 0171019
Molecular Formula : C17H25LiN2O4
Molecular Weight : 328.34
stdClass Object
(
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Vildagliptin (IPRSV001) -from IPC
stdClass Object
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[catalogue_number] => PA 22 0171020
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[chemical_name] =>
[weight] => 225.29
[form] => C12H19NO3
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(3-Hydroxyadamantan-1-yl)glycine
Catalogue No.:PA 22 0171020
Molecular Formula : C12H19NO3
Molecular Weight : 225.29
stdClass Object
(
[pname] => 1-(3-Hydroxy-1-adamantyl)ethanone
[catalogue_number] => PA 22 0171021
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 194.27
[form] => C12H18O2
[cas] => 39917-38-9
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1-(3-Hydroxy-1-adamantyl)ethanone
Catalogue No.:PA 22 0171021
Molecular Formula : C12H18O2
Molecular Weight : 194.27
stdClass Object
(
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[catalogue_number] => PA 22 0171022
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 264.07
[form] => C7H9IN2O
[cas] => 1811569-16-0
[pslug] => 1811569-16-0-s-1-2-iodoacetyl-pyrrolidine-2-carbonitrile-pa220171022
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(S)-1-(2-Iodoacetyl)pyrrolidine-2-carbonitrile
Catalogue No.:PA 22 0171022
Molecular Formula : C7H9IN2O
Molecular Weight : 264.07
stdClass Object
(
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[catalogue_number] => PA 22 0171023
[category_ids] => ,75,76,78,70,82,
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[weight] => 317.39
[form] => C17H23N3O3
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Vildagliptin imine N-oxide impurity
Catalogue No.:PA 22 0171023
Molecular Formula : C17H23N3O3
Molecular Weight : 317.39
stdClass Object
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[catalogue_number] => PA 22 0171025
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[chemical_name] =>
[weight] => 239.27
[form] => C12H17NO4
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4-(((5-(Hydroxymethyl)furan-2-yl)methyl)amino)hex-5-enoic Acid
Catalogue No.:PA 22 0171025
Molecular Formula : C12H17NO4
Molecular Weight : 239.27
stdClass Object
(
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[catalogue_number] => PA 22 0171024
[category_ids] => 82,78,76,75,70
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[weight] => 336.43
[form] => C18H28N2O4
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Vildagliptin Carboxylic Acid Methyl Ester
Catalogue No.:PA 22 0171024
Molecular Formula : C18H28N2O4
Molecular Weight : 336.43
stdClass Object
(
[pname] => 2-((S)-1-(((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)glycyl)pyrrolidin-2-yl)-4,5-dihydrothiazole-4-carboxylic Acid
[catalogue_number] => PA 22 0171026
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[weight] => 407.53
[form] => C20H29N3O4S
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2-((S)-1-(((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)glycyl)pyrrolidin-2-yl)-4,5-dihydrothiazole-4-carboxylic Acid
Catalogue No.:PA 22 0171026
Molecular Formula : C20H29N3O4S
Molecular Weight : 407.53
stdClass Object
(
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[weight] => 301.39
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(S)-1-(2-(((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)imino)acetyl)pyrrolidine-2-carbonitrile
Catalogue No.:PA 22 0171027
Molecular Formula : C17H23N3O2
Molecular Weight : 301.39
stdClass Object
(
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[catalogue_number] => PA 22 0171004
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[chemical_name] =>
[weight] => 304.39
[form] => C17H24N2O3
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(S)-2-((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Catalogue No.:PA 22 0171004
Molecular Formula : C17H24N2O3
Molecular Weight : 304.39
stdClass Object
(
[pname] => (1R)-2-((2S)-2-Amino-2-((1r,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)cyclopent-3-ene-1-carboxamide
[catalogue_number] => PA 22 0171028
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[weight] => 318.42
[form] => C18H26N2O3
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(1R)-2-((2S)-2-Amino-2-((1r,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)cyclopent-3-ene-1-carboxamide
Catalogue No.:PA 22 0171028
Molecular Formula : C18H26N2O3
Molecular Weight : 318.42
stdClass Object
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[catalogue_number] => PA 22 0171029
[category_ids] => 162,82,78,76,75,70
[chemical_name] =>
[weight] => 332.4
[form] => C17H24N4O3
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stdClass Object
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[pname] => Vildagliptin N-Nitroso-L-Proline Methyl Ester
[catalogue_number] => PA 22 0171030
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 158.16
[form] => C6H10N2O3
[cas] => 35909-01-4
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Vildagliptin N-Nitroso-L-Proline Methyl Ester
Catalogue No.:PA 22 0171030
Molecular Formula : C6H10N2O3
Molecular Weight : 158.16
stdClass Object
(
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[catalogue_number] => PA 22 0171031
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[chemical_name] =>
[weight] => 143.15
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(S)-1-Nitrosopyrrolidine-2-carboxamide
Catalogue No.:PA 22 0171031
Molecular Formula : C5H9N3O2
Molecular Weight : 143.15
stdClass Object
(
[pname] => (S)-1-(2,2-Dichloroacetyl)pyrrolidine-2-carbonitrile
[catalogue_number] => PA 22 0171032
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[chemical_name] =>
[weight] => 207.05
[form] => C7H8Cl2N2O
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(S)-1-(2,2-Dichloroacetyl)pyrrolidine-2-carbonitrile
Catalogue No.:PA 22 0171032
Molecular Formula : C7H8Cl2N2O
Molecular Weight : 207.05
stdClass Object
(
[pname] => (2S,2'S)-1,1'-(2,2'-(Adamantane-1,3-diylbis(azanediyl))bis(acetyl))bis(pyrrolidine-2-carbonitrile)
[catalogue_number] => PA 22 0171033
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[chemical_name] =>
[weight] => 438.58
[form] => C24H34N6O2
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(2S,2'S)-1,1'-(2,2'-(Adamantane-1,3-diylbis(azanediyl))bis(acetyl))bis(pyrrolidine-2-carbonitrile)
Catalogue No.:PA 22 0171033
Molecular Formula : C24H34N6O2
Molecular Weight : 438.58
stdClass Object
(
[pname] => (2S)-1-((3-(2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethoxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile
[catalogue_number] => PA 22 0171034
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[weight] => 439.56
[form] => C24H33N5O3
[cas] => NA
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(2S)-1-((3-(2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethoxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile
Catalogue No.:PA 22 0171034
Molecular Formula : C24H33N5O3
Molecular Weight : 439.56
stdClass Object
(
[pname] => 2-(3-Hydroxyadamantan-1-yl)-1-iminohexahydropyrrolo[1,2-a]pyrazin-4(1H)-one Hydrochloride
[catalogue_number] => PA 22 0171035
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 339.86
[form] => C17H26ClN3O2
[cas] => 2663700-61-4
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2-(3-Hydroxyadamantan-1-yl)-1-iminohexahydropyrrolo[1,2-a]pyrazin-4(1H)-one Hydrochloride
Catalogue No.:PA 22 0171035
Molecular Formula : C17H26ClN3O2
Molecular Weight : 339.86
stdClass Object
(
[pname] => Vildagliptin Chloro Impurity
[catalogue_number] => PA 22 0171036
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 337.85
[form] => C17H24ClN3O2
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Vildagliptin Chloro Impurity
Catalogue No.:PA 22 0171036
Molecular Formula : C17H24ClN3O2
Molecular Weight : 337.85
stdClass Object
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[pname] => N-Nitroso Analogue Of Vildagliptin Carboxylic Acid Impurity
[catalogue_number] => PA 22 0171040
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[weight] => 351.4
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N-Nitroso Analogue Of Vildagliptin Carboxylic Acid Impurity
stdClass Object
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[pname] => N-(2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethyl)-N-((1R,3S,5R)-3-hydroxyadamantan-1-yl)nitrous amide
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[weight] => 332.4
[form] => C17H24N4O3
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N-(2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethyl)-N-((1R,3S,5R)-3-hydroxyadamantan-1-yl)nitrous amide
stdClass Object
(
[pname] => N-Nitroso-Vildagliptin amide Impurity
[catalogue_number] => PA 22 0171045
[category_ids] => ,75,76,78,82,162,
[chemical_name] =>
[weight] => 350.42
[form] => C17H26N4O4
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N-Nitroso-Vildagliptin amide Impurity
Catalogue No.:PA 22 0171045
Molecular Formula : C17H26N4O4
Molecular Weight : 350.42
stdClass Object
(
[pname] => Vildagliptin Racemic
[catalogue_number] => PA 22 0171047
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 303.41
[form] => C17H25N3O2
[cas] => 1360862-63-0
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Catalogue No.:PA 22 0171047
Molecular Formula : C17H25N3O2
Molecular Weight : 303.41
stdClass Object
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[weight] => 303.41
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2-((1s,3s,5R,7S)-3-Hydroxyadamantan-1-yl)-1-iminohexahydropyrrolo[1,2-a]pyrazin-4(1H)-one
Catalogue No.:PA 22 0171049
Molecular Formula : C17H25N3O2
Molecular Weight : 303.41
stdClass Object
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[pname] => Vildagliptin Hydroxy Impurity
[catalogue_number] => PA 22 0171048
[category_ids] => ,75,76,78,82,
[chemical_name] =>
[weight] => 319.41
[form] => C17H25N3O3
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Vildagliptin Hydroxy Impurity
Catalogue No.:PA 22 0171048
Molecular Formula : C17H25N3O3
Molecular Weight : 319.41
stdClass Object
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[catalogue_number] => PA 22 0171051
[category_ids] => ,82,78,76,75,
[chemical_name] =>
[weight] => 321.42
[form] => C17H27N3O3
[cas] => 2509147-39-9
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1-[2-[(3-Hydroxy-1-adamantyl) amino] acetyl]pyrrolidine-2-carboxamide
Catalogue No.:PA 22 0171051
Molecular Formula : C17H27N3O3
Molecular Weight : 321.42
