Vonoprazan-impurities | Pharmaffiliates

Vonoprazan

Vonoprazan is used in form of the fumarate for the treatment of gastroduodenal ulcer and reflux esophagitis. It is a first-in-class potassium-competitive acid blocker.Reference standards of Vonoprazan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanol
    [catalogue_number] => PA 22 0471000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 332.35
    [form] => C16H13FN2O3S
    [cas] => 2169271-28-5
    [pslug] => 2169271-28-5-5-2-fluorophenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-methanol-pa220471000
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PA 22 0471000

(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanol


  • Catalogue No.:PA 22 0471000

  • CAS :

    2169271-28-5

  • Molecular Formula : C16H13FN2O3S

  • Molecular Weight : 332.35

stdClass Object
(
    [pname] => Vonoprazan Sulfonyl Aldehyde Impurity
    [catalogue_number] => PA 22 0471001
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 330.33
    [form] => C16H11FN2O3S
    [cas] => 881677-11-8
    [pslug] => 881677-11-8-vonoprazan-sulfonyl-aldehyde-impurity-pa220471001
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PA 22 0471001

Vonoprazan Sulfonyl Aldehyde Impurity


  • Catalogue No.:PA 22 0471001

  • CAS :

    881677-11-8

  • Molecular Formula : C16H11FN2O3S

  • Molecular Weight : 330.33

stdClass Object
(
    [pname] => 5-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1,2,3,4-tetrahydropyridin-2-ol
    [catalogue_number] => PA 22 0471002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 365.42
    [form] => C17H20FN3O3S
    [cas] => 2416241-96-6
    [pslug] => 2416241-96-6-5-2-2-fluorophenyl-4-methylamino-methyl-1h-pyrrol-1-yl-sulfonyl-1-2-3-4-tetrahydropyridin-2-ol-pa220471002
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PA 22 0471002

5-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1,2,3,4-tetrahydropyridin-2-ol


  • Catalogue No.:PA 22 0471002

  • CAS :

    2416241-96-6

  • Molecular Formula : C17H20FN3O3S

  • Molecular Weight : 365.42

stdClass Object
(
    [pname] => 1-(5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
    [catalogue_number] => PA 22 0471003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 349.42
    [form] => C17H20FN3O2S
    [cas] => 2416241-97-7
    [pslug] => 2416241-97-7-1-5-2-fluorophenyl-1-1-4-5-6-tetrahydropyridin-3-yl-sulfonyl-1h-pyrrol-3-yl-n-methylmethanamine-pa220471003
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PA 22 0471003

1-(5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine


  • Catalogue No.:PA 22 0471003

  • CAS :

    2416241-97-7

  • Molecular Formula : C17H20FN3O2S

  • Molecular Weight : 349.42

stdClass Object
(
    [pname] => N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine
    [catalogue_number] => PA 22 0471004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 327.4
    [form] => C17H17N3O2S
    [cas] => 881732-90-7
    [pslug] => 881732-90-7-n-methyl-1-5-phenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-methanamine-pa220471004
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PA 22 0471004

N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine


  • Catalogue No.:PA 22 0471004

  • CAS :

    881732-90-7

  • Molecular Formula : C17H17N3O2S

  • Molecular Weight : 327.4

stdClass Object
(
    [pname] => N,N-Dimethylmethanamine Vonoprazan
    [catalogue_number] => PA 22 0471005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 359.42
    [form] => C18H18FN3O2S
    [cas] => 1885094-62-1
    [pslug] => 1885094-62-1-n-n-dimethylmethanamine-vonoprazan-pa220471005
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PA 22 0471005

N,N-Dimethylmethanamine Vonoprazan


  • Catalogue No.:PA 22 0471005

  • CAS :

    1885094-62-1

  • Molecular Formula : C18H18FN3O2S

  • Molecular Weight : 359.42

stdClass Object
(
    [pname] => (5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methanamine
    [catalogue_number] => PA 22 0471006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 335.4
    [form] => C16H18FN3O2S
    [cas] => NA
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PA 22 0471006

(5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methanamine


  • Catalogue No.:PA 22 0471006

  • CAS :

    NA

  • Molecular Formula : C16H18FN3O2S

  • Molecular Weight : 335.4

stdClass Object
(
    [pname] => N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylaspartic Acid
    [catalogue_number] => PA 22 0471007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 461.46
    [form] => C21H20FN3O6S
    [cas] => 2170020-79-6
    [pslug] => 2170020-79-6-n-5-2-fluorophenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-methyl-n-methylaspartic-acid-pa220471007
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PA 22 0471007

N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylaspartic Acid


  • Catalogue No.:PA 22 0471007

  • CAS :

    2170020-79-6

  • Molecular Formula : C21H20FN3O6S

  • Molecular Weight : 461.46

stdClass Object
(
    [pname] => Vonoprazan Carbaldehyde Impurity
    [catalogue_number] => PA 22 0471008
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 189.19
    [form] => C11H8FNO
    [cas] => 881674-56-2
    [pslug] => 881674-56-2-vonoprazan-carbaldehyde-impurity-pa220471008
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PA 22 0471008

Vonoprazan Carbaldehyde Impurity


  • Catalogue No.:PA 22 0471008

  • CAS :

    881674-56-2

  • Molecular Formula : C11H8FNO

  • Molecular Weight : 189.19

stdClass Object
(
    [pname] => 1-(5-(2-Fluorophenyl)-1-(pyridin-4-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
    [catalogue_number] => PA 22 0471010
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 345.39
    [form] => C17H16FN3O2S
    [cas] => 2771609-43-7
    [pslug] => 2771609-43-7-1-5-2-fluorophenyl-1-pyridin-4-ylsulfonyl-1h-pyrrol-3-yl-n-methylmethanamine-pa220471010
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PA 22 0471010

1-(5-(2-Fluorophenyl)-1-(pyridin-4-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine


  • Catalogue No.:PA 22 0471010

  • CAS :

    2771609-43-7

  • Molecular Formula : C17H16FN3O2S

  • Molecular Weight : 345.39

stdClass Object
(
    [pname] => 1-(5-(3-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
    [catalogue_number] => PA 22 0471011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 345.39
    [form] => C17H16FN3O2S
    [cas] => 881733-45-5
    [pslug] => 881733-45-5-1-5-3-fluorophenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-n-methylmethanamine-pa220471011
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PA 22 0471011

1-(5-(3-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine


  • Catalogue No.:PA 22 0471011

  • CAS :

    881733-45-5

  • Molecular Formula : C17H16FN3O2S

  • Molecular Weight : 345.39

stdClass Object
(
    [pname] => 1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
    [catalogue_number] => PA 22 0471009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 345.39
    [form] => C17H16FN3O2S
    [cas] => 881733-36-4
    [pslug] => 881733-36-4-1-5-4-fluorophenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-n-methylmethanamine-pa220471009
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PA 22 0471009

1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine


  • Catalogue No.:PA 22 0471009

  • CAS :

    881733-36-4

  • Molecular Formula : C17H16FN3O2S

  • Molecular Weight : 345.39

stdClass Object
(
    [pname] => 1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine
    [catalogue_number] => PA 22 0471012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 204.25
    [form] => C12H13FN2
    [cas] => 1610043-62-3
    [pslug] => 1610043-62-3-1-5-2-fluorophenyl-1h-pyrrol-3-yl-n-methylmethanamine-pa220471012
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PA 22 0471012

1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine


  • Catalogue No.:PA 22 0471012

  • CAS :

    1610043-62-3

  • Molecular Formula : C12H13FN2

  • Molecular Weight : 204.25

stdClass Object
(
    [pname] => N-Nitroso Vonoprazan
    [catalogue_number] => PA 22 0471013
    [category_ids] => 162,82,78,76,75,70
    [chemical_name] => 
    [weight] => 374.39
    [form] => C17H15FN4O3S
    [cas] => 2932441-73-9
    [pslug] => 2932441-73-9-n-nitroso-vonoprazan-pa220471013
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PA 22 0471013

N-Nitroso Vonoprazan


  • Catalogue No.:PA 22 0471013

  • CAS :

    2932441-73-9

  • Molecular Formula : C17H15FN4O3S

  • Molecular Weight : 374.39

stdClass Object
(
    [pname] => Pyridine-3-sulfonic Acid
    [catalogue_number] => PA 22 0471033
    [category_ids] => ,79,80,78,76,75,
    [chemical_name] => 
    [weight] => 159.16
    [form] => C5H5NO3S
    [cas] => 636-73-7
    [pslug] => 636-73-7-pyridine-3-sulfonic-acid-pa220471033
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PA 22 0471033

Pyridine-3-sulfonic Acid


  • Catalogue No.:PA 22 0471033

  • CAS :

    636-73-7

  • Molecular Formula : C5H5NO3S

  • Molecular Weight : 159.16

stdClass Object
(
    [pname] => 2-Fluorobenzaldehyde
    [catalogue_number] => PA 22 0471041
    [category_ids] => ,75,78,79,82,
    [chemical_name] => 
    [weight] => 124.11
    [form] => C7H5FO
    [cas] => 446-52-6
    [pslug] => 446-52-6-2-fluorobenzaldehyde-pa220471041
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PA 22 0471041

2-Fluorobenzaldehyde


  • Catalogue No.:PA 22 0471041

  • CAS :

    446-52-6

  • Molecular Formula : C7H5FO

  • Molecular Weight : 124.11

stdClass Object
(
    [pname] => 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile
    [catalogue_number] => PA 22 0471042
    [category_ids] => ,75,78,79,82,
    [chemical_name] => 
    [weight] => 202.19
    [form] => C11H7FN2O
    [cas] => 312307-38-3
    [pslug] => 312307-38-3-2-2-2-fluorophenyl-2-oxoethyl-malononitrile-pa220471042
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PA 22 0471042

2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile


  • Catalogue No.:PA 22 0471042

  • CAS :

    312307-38-3

  • Molecular Formula : C11H7FN2O

  • Molecular Weight : 202.19

stdClass Object
(
    [pname] => 2-Chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
    [catalogue_number] => PA 22 0471043
    [category_ids] => ,75,78,79,82,
    [chemical_name] => 
    [weight] => 220.63
    [form] => C11H6ClFN2
    [cas] => 1240948-72-4
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PA 22 0471043

2-Chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile


  • Catalogue No.:PA 22 0471043

  • CAS :

    1240948-72-4

  • Molecular Formula : C11H6ClFN2

  • Molecular Weight : 220.63

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    [pname] => 5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile
    [catalogue_number] => PA 22 0471044
    [category_ids] => ,75,78,79,82,
    [chemical_name] => 
    [weight] => 186.19
    [form] => C11H7FN2
    [cas] => 1240948-77-9
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PA 22 0471044

5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile


  • Catalogue No.:PA 22 0471044

  • CAS :

    1240948-77-9

  • Molecular Formula : C11H7FN2

  • Molecular Weight : 186.19

stdClass Object
(
    [pname] => (5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine
    [catalogue_number] => PA 22 0471047
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 331.37
    [form] => C16H14FN3O2S
    [cas] => 1807642-41-6
    [pslug] => 1807642-41-6-5-2-fluorophenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-methanamine-pa220471047
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PA 22 0471047

(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine


  • Catalogue No.:PA 22 0471047

  • CAS :

    1807642-41-6

  • Molecular Formula : C16H14FN3O2S

  • Molecular Weight : 331.37

stdClass Object
(
    [pname] => 1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine Fumarate
    [catalogue_number] => PA 22 0471049
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 320.32
    [form] => C16H17FN2O4
    [cas] => 1885094-64-3
    [pslug] => 1885094-64-3-1-5-2-fluorophenyl-1h-pyrrol-3-yl-n-methylmethanamine-fumarate-pa220471049
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PA 22 0471049

1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine Fumarate


  • Catalogue No.:PA 22 0471049

  • CAS :

    1885094-64-3

  • Molecular Formula : C16H17FN2O4

  • Molecular Weight : 320.32

stdClass Object
(
    [pname] => N,N-Dimethylmethanamine Vonoprazan Fumarate Salt
    [catalogue_number] => PA 22 0471050
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 475.49
    [form] => C22H22FN3O6S
    [cas] => 2689014-77-3
    [pslug] => 2689014-77-3-n-n-dimethylmethanamine-vonoprazan-fumarate-salt-pa220471050
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PA 22 0471050

N,N-Dimethylmethanamine Vonoprazan Fumarate Salt


  • Catalogue No.:PA 22 0471050

  • CAS :

    2689014-77-3

  • Molecular Formula : C22H22FN3O6S

  • Molecular Weight : 475.49