adapalene
Intermediates
- Adapalene is marketed by Galderma under the trade names Differin and Adaferin. It is a member of the retinoid drug class that is typically found in topical formulations used for the treatment of acne. It may be used to treat keratosis pilaris as well as other skin conditions as off-label use. Reference standards of Adapalene API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Adapalene
[catalogue_number] => PA 01 22000
[category_ids] => ,70,75,76,78,82,85,88,91,
[chemical_name] =>
[weight] => 412.53
[form] => C28H28O3
[cas] => 106685-40-9
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Catalogue No.:PA 01 22000
Molecular Formula : C28H28O3
Molecular Weight : 412.53
stdClass Object
(
[pname] => Adapalene - Impurity A
[catalogue_number] => PA 01 22010
[category_ids] => ,99,76,75,70,78,82,
[chemical_name] =>
[weight] => 342.34
[form] => C22H14O4
[cas] => 932033-58-4
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Catalogue No.:PA 01 22010
Molecular Formula : C22H14O4
Molecular Weight : 342.34
stdClass Object
(
[pname] => Adapalene - Impurity B
[catalogue_number] => PA 01 22020
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 428.53
[form] => C28H28O4
[cas] => 1346599-76-5
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Catalogue No.:PA 01 22020
Molecular Formula : C28H28O4
Molecular Weight : 428.53
stdClass Object
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[pname] => Adapalene - Impurity C
[catalogue_number] => PA 01 22030
[category_ids] => ,99,82,78,76,75,70,
[chemical_name] =>
[weight] => 242.36
[form] => C17H22O
[cas] => 43109-77-9
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Catalogue No.:PA 01 22030
Molecular Formula : C17H22O
Molecular Weight : 242.36
stdClass Object
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[pname] => Adapalene - Impurity D
[catalogue_number] => PA 01 22040
[category_ids] => ,99,82,78,76,75,70,
[chemical_name] =>
[weight] => 482.7
[form] => C34H42O2
[cas] => 932033-57-3
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stdClass Object
(
[pname] => Methyl 6-Bromo-2-napthoate
[catalogue_number] => PA 01 22510
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 265.1
[form] => C12H9BrO2
[cas] => 33626-98-1
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Methyl 6-Bromo-2-napthoate
stdClass Object
(
[pname] => Adapalene Methyl Ester
[catalogue_number] => PA 01 22520
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 426.55
[form] => C29H30O3
[cas] => 106685-41-0
[pslug] => 106685-41-0-adapalene-methyl-ester-pa0122520
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Catalogue No.:PA 01 22520
Molecular Formula : C29H30O3
Molecular Weight : 426.55
stdClass Object
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[pname] => 2-(1-Adamantyl)-4-bromoanisole
[catalogue_number] => PA 01 22530
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[weight] => 321.25
[form] => C17H21BrO
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2-(1-Adamantyl)-4-bromoanisole
Catalogue No.:PA 01 22530
Molecular Formula : C17H21BrO
Molecular Weight : 321.25
stdClass Object
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[pname] => Dimethyl [2,2'-binaphthalene]-6,6'-dicarboxylate
[catalogue_number] => PAI 01 018010
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[weight] => 370.4
[form] => C24H18O4
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Dimethyl [2,2'-binaphthalene]-6,6'-dicarboxylate
stdClass Object
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[pname] => 6-Bromo-2-naphthalenemethanol
[catalogue_number] => PA 01 0221000
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[chemical_name] =>
[weight] => 237.10
[form] => C11H9BrO
[cas] => 100751-63-1
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6-Bromo-2-naphthalenemethanol
Catalogue No.:PA 01 0221000
Molecular Formula : C11H9BrO
Molecular Weight : 237.10
stdClass Object
(
[pname] => 2-(Adamantan-1-yl)-4-bromophenol
[catalogue_number] => PA 01 0221004
[category_ids] => ,75,76,78,70,82,
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[weight] => 307.23
[form] => C16H19BrO
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2-(Adamantan-1-yl)-4-bromophenol
Catalogue No.:PA 01 0221004
Molecular Formula : C16H19BrO
Molecular Weight : 307.23
stdClass Object
(
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[catalogue_number] => PA 01 0221005
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[weight] => 442.56
[form] => C29H30O4
[cas] => NA
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Methyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate
Catalogue No.:PA 01 0221005
Molecular Formula : C29H30O4
Molecular Weight : 442.56
stdClass Object
(
[pname] => O-Desmethyl adapalene
[catalogue_number] => PA 01 0221006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 398.5
[form] => C27H26O3
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stdClass Object
(
[pname] => Adapalene Acyl-Glucuronide
[catalogue_number] => PA 01 0221007
[category_ids] => ,70,75,76,78,82,95,
[chemical_name] =>
[weight] => 588.65
[form] => C34H36O9
[cas] => NA
[pslug] => adapalene-acyl-glucuronide-pa010221007
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Adapalene Acyl-Glucuronide
Catalogue No.:PA 01 0221007
Molecular Formula : C34H36O9
Molecular Weight : 588.65
stdClass Object
(
[pname] => 3-Hydroxy Adapalene methyl ester
[catalogue_number] => PA 01 0221008
[category_ids] => ,75,76,78,70,82,
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[weight] => 442.56
[form] => C29H30O4
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3-Hydroxy Adapalene methyl ester
Catalogue No.:PA 01 0221008
Molecular Formula : C29H30O4
Molecular Weight : 442.56
stdClass Object
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[pname] => O-Desmethyl Adapalene-13C6
[catalogue_number] => PA 01 0221009
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 404.46
[form] => C2113C6H26O3
[cas] => NA
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O-Desmethyl Adapalene-13C6
Catalogue No.:PA 01 0221009
Molecular Formula : C2113C6H26O3
Molecular Weight : 404.46
stdClass Object
(
[pname] => 6-(3-(3-Bromoadamantan-1-yl)-4-methoxyphenyl)-2-naphthoic Acid
[catalogue_number] => PAI 01 018011
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[chemical_name] =>
[weight] => 491.43
[form] => C28H27BrO3
[cas] => NA
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6-(3-(3-Bromoadamantan-1-yl)-4-methoxyphenyl)-2-naphthoic Acid
Catalogue No.:PAI 01 018011
Molecular Formula : C28H27BrO3
Molecular Weight : 491.43
stdClass Object
(
[pname] => 6-Bromo-2-naphthoic Acid
[catalogue_number] => PA 01 0221010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 251.08
[form] => C11H7BrO2
[cas] => 5773-80-8
[pslug] => 5773-80-8-6-bromo-2-naphthoic-acid-pa010221010
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Catalogue No.:PA 01 0221010
Molecular Formula : C11H7BrO2
Molecular Weight : 251.08
stdClass Object
(
[pname] => Adapalene Dimer Impurity
[catalogue_number] => PA 01 0221011
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 688.82
[form] => C46H40O6
[cas] => NA
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Catalogue No.:PA 01 0221011
Molecular Formula : C46H40O6
Molecular Weight : 688.82
stdClass Object
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[pname] => 6-[(3-Adamantyl-4-Methoxyphenyl)]-2-Naphthoic Acid Ethyl Ester
[catalogue_number] => PAI 01 018012
[category_ids] => ,70,
[chemical_name] =>
[weight] => 440.58
[form] => C30H32O3
[cas] => 951645-46-8
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6-[(3-Adamantyl-4-Methoxyphenyl)]-2-Naphthoic Acid Ethyl Ester
Catalogue No.:PAI 01 018012
Molecular Formula : C30H32O3
Molecular Weight : 440.58
stdClass Object
(
[pname] => Ethyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate
[catalogue_number] => PAI 01 018013
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[chemical_name] =>
[weight] => 456.58
[form] => C30H32O4
[cas] => NA
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Ethyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate
Catalogue No.:PAI 01 018013
Molecular Formula : C30H32O4
Molecular Weight : 456.58
stdClass Object
(
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[catalogue_number] => PA 01 0221012
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 292.33
[form] => C19H16O3
[cas] => 128272-36-6
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Methyl 6-(4-methoxyphenyl)-2-naphthoate
Catalogue No.:PA 01 0221012
Molecular Formula : C19H16O3
Molecular Weight : 292.33
stdClass Object
(
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[catalogue_number] => PA 01 0221013
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[chemical_name] =>
[weight] => 412.53
[form] => C28H28O3
[cas] => 106685-43-2
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Methyl 6-(3-((3r,5r,7r)-adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoate
Catalogue No.:PA 01 0221013
Molecular Formula : C28H28O3
Molecular Weight : 412.53
stdClass Object
(
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[catalogue_number] => PA 01 0221014
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 278.31
[form] => C18H14O3
[cas] => 107430-57-9
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4-(6-Methoxynaphthalen-2-yl)benzoic Acid
Catalogue No.:PA 01 0221014
Molecular Formula : C18H14O3
Molecular Weight : 278.31
stdClass Object
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[catalogue_number] => PAI 01 018014
[category_ids] => ,70,
[chemical_name] =>
[weight] => 337.26
[form] => C17H21BrO2
[cas] => NA
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3-(5-Bromo-2-methoxyphenyl)adamantan-1-ol
Catalogue No.:PAI 01 018014
Molecular Formula : C17H21BrO2
Molecular Weight : 337.26
stdClass Object
(
[pname] => (3-(3-Hydroxyadamantan-1-yl)-4-methoxyphenyl)boronic Acid
[catalogue_number] => PAI 01 018015
[category_ids] => ,70,
[chemical_name] =>
[weight] => 302.18
[form] => C17H23BO4
[cas] => NA
[pslug] => 3-3-hydroxyadamantan-1-yl-4-methoxyphenyl-boronic-acid-pai01018015
[latest_product] => 0
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(3-(3-Hydroxyadamantan-1-yl)-4-methoxyphenyl)boronic Acid
Catalogue No.:PAI 01 018015
Molecular Formula : C17H23BO4
Molecular Weight : 302.18
stdClass Object
(
[pname] => 3-(5-Bromo-2-hydroxyphenyl)adamantan-1-ol
[catalogue_number] => PAI 01 018016
[category_ids] => ,70,
[chemical_name] =>
[weight] => 323.23
[form] => C16H19BrO2
[cas] => NA
[pslug] => 3-5-bromo-2-hydroxyphenyl-adamantan-1-ol-pai01018016
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3-(5-Bromo-2-hydroxyphenyl)adamantan-1-ol
Catalogue No.:PAI 01 018016
Molecular Formula : C16H19BrO2
Molecular Weight : 323.23
stdClass Object
(
[pname] => 1,3-Bis(5-bromo-2-methoxyphenyl)adamantane
[catalogue_number] => PA 01 0221016
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 506.28
[form] => C24H26Br2O2
[cas] => 932033-56-2
[pslug] => 932033-56-2-1-3-bis-5-bromo-2-methoxyphenyl-adamantane-pa010221016
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1,3-Bis(5-bromo-2-methoxyphenyl)adamantane
Catalogue No.:PA 01 0221016
Molecular Formula : C24H26Br2O2
Molecular Weight : 506.28
