avanafil
Chemically, it is a derivative of pyrimidine and is only available as the S-enantiomer. Avanafil is a new phosphodiesterase-5 inhibitor that is faster acting and more selective than other drugs belonging to the same class. . Reference standards of Avanafil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Avanafil
[catalogue_number] => PA 28 44000
[category_ids] => ,80,69,71,78,70,82,92,
[chemical_name] =>
[weight] => 483.95
[form] => C23H26ClN7O3
[cas] => 330784-47-9
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Catalogue No.:PA 28 44000
Molecular Formula : C23H26ClN7O3
Molecular Weight : 483.95
stdClass Object
(
[pname] => Avanafil Amide Analog
[catalogue_number] => PA 28 44520
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 391.85
[form] => C18H22ClN5O3
[cas] => 372117-54-9
[pslug] => 372117-54-9-avanafil-amide-analog-pa2844520
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Catalogue No.:PA 28 44520
Molecular Formula : C18H22ClN5O3
Molecular Weight : 391.85
stdClass Object
(
[pname] => Avanafil N-Methyl Analog
[catalogue_number] => PA 28 44530
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 405.88
[form] => C19H24ClN5O3
[cas] => 372117-53-8
[pslug] => 372117-53-8-avanafil-n-methyl-analog-pa2844530
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Catalogue No.:PA 28 44530
Molecular Formula : C19H24ClN5O3
Molecular Weight : 405.88
stdClass Object
(
[pname] => Avanafil N-ethyl Analog
[catalogue_number] => PA 28 44540
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 419.91
[form] => C20H26ClN5O3
[cas] => 2520114-39-8
[pslug] => 2520114-39-8-avanafil-n-ethyl-analog-pa2844540
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Catalogue No.:PA 28 44540
Molecular Formula : C20H26ClN5O3
Molecular Weight : 419.91
stdClass Object
(
[pname] => Avanafil O-Desmethyl Analog
[catalogue_number] => PA 28 44550
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 469.92
[form] => C22H24ClN7O3
[cas] => 330785-05-2
[pslug] => 330785-05-2-avanafil-o-desmethyl-analog-pa2844550
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Avanafil O-Desmethyl Analog
Catalogue No.:PA 28 44550
Molecular Formula : C22H24ClN7O3
Molecular Weight : 469.92
stdClass Object
(
[pname] => Avanafil Ethyl Ester Analog
[catalogue_number] => PA 28 44560
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[chemical_name] =>
[weight] => 420.89
[form] => C20H25ClN4O4
[cas] => 1638497-22-9
[pslug] => 1638497-22-9-avanafil-ethyl-ester-analog-pa2844560
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Avanafil Ethyl Ester Analog
Catalogue No.:PA 28 44560
Molecular Formula : C20H25ClN4O4
Molecular Weight : 420.89
stdClass Object
(
[pname] => R-Avanafil
[catalogue_number] => PA 28 44580
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 483.95
[form] => C23H26ClN7O3
[cas] => 1638497-26-3
[pslug] => 1638497-26-3-r-avanafil-pa2844580
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Catalogue No.:PA 28 44580
Molecular Formula : C23H26ClN7O3
Molecular Weight : 483.95
stdClass Object
(
[pname] => Avanafil Keto Analog
[catalogue_number] => PA 28 44590
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 400.82
[form] => C18H17ClN6O3
[cas] => 1452128-53-8
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Catalogue No.:PA 28 44590
Molecular Formula : C18H17ClN6O3
Molecular Weight : 400.82
stdClass Object
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[pname] => Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
[catalogue_number] => PA 28 44600
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[weight] => 383.85
[form] => C16H18ClN3O4S
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Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 44600
Molecular Formula : C16H18ClN3O4S
Molecular Weight : 383.85
stdClass Object
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[pname] => Avanafi Thiomethyl Analog
[catalogue_number] => PA 28 44610
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[weight] => 430.91
[form] => C19H19ClN6O2S
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Avanafi Thiomethyl Analog
Catalogue No.:PA 28 44610
Molecular Formula : C19H19ClN6O2S
Molecular Weight : 430.91
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[pname] => Avanafi Dichloro Analog
[catalogue_number] => PA 28 44620
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[weight] => 518.4
[form] => C23H25Cl2N7O3
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stdClass Object
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[pname] => 4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid
[catalogue_number] => PA 28 44640
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[chemical_name] =>
[weight] => 515.95
[form] => C23H26ClN7O5
[cas] => 2748151-94-0
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4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid
Catalogue No.:PA 28 44640
Molecular Formula : C23H26ClN7O5
Molecular Weight : 515.95
stdClass Object
(
[pname] => 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid
[catalogue_number] => PA 28 44650
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[weight] => 339.8
[form] => C14H14ClN3O3S
[cas] => 330786-34-0
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4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid
stdClass Object
(
[pname] => Avanafil Isopropyl Amide Analog
[catalogue_number] => PA 28 44660
[category_ids] => ,80,71,78,70,82,79,75,
[chemical_name] =>
[weight] => 433.93
[form] => C21H28ClN5O3
[cas] => 2520114-11-6
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Avanafil Isopropyl Amide Analog
Catalogue No.:PA 28 44660
Molecular Formula : C21H28ClN5O3
Molecular Weight : 433.93
stdClass Object
(
[pname] => Avanafil-13C5,15N
[catalogue_number] => PA STI 009310
[category_ids] => ,80,69,71,78,70,82,98,
[chemical_name] =>
[weight] => 489.91
[form] => C1813C5H26ClN615NO3
[cas] => 1276495-36-3
[pslug] => 1276495-36-3-avanafil-13c5-15n-pasti009310
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Catalogue No.:PA STI 009310
Molecular Formula : C1813C5H26ClN615NO3
Molecular Weight : 489.91
stdClass Object
(
[pname] => Avanafil Dimer
[catalogue_number] => PA 28 44670
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 858.78
[form] => C41H45Cl2N11O6
[cas] => 1643811-27-1
[pslug] => 1643811-27-1-avanafil-dimer-pa2844670
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Catalogue No.:PA 28 44670
Molecular Formula : C41H45Cl2N11O6
Molecular Weight : 858.78
stdClass Object
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[catalogue_number] => PA 28 0441000
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[weight] => 367.85
[form] => C16H18ClN3O3S
[cas] => 2520114-23-0
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Ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441000
Molecular Formula : C16H18ClN3O3S
Molecular Weight : 367.85
stdClass Object
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[catalogue_number] => PA 28 0441001
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[weight] => 402.29
[form] => C16H17Cl2N3O3S
[cas] => 2250242-48-7
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Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441001
Molecular Formula : C16H17Cl2N3O3S
Molecular Weight : 402.29
stdClass Object
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[catalogue_number] => PA 28 0441002
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[weight] => 337.76
[form] => C15H16ClN3O4
[cas] => 330785-99-4
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Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441002
Molecular Formula : C15H16ClN3O4
Molecular Weight : 337.76
stdClass Object
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[chemical_name] =>
[weight] => 420.89
[form] => C20H25ClN4O4
[cas] => 330785-83-6
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(S)-Ethyl 4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441004
Molecular Formula : C20H25ClN4O4
Molecular Weight : 420.89
stdClass Object
(
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[catalogue_number] => PA 28 0441005
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[chemical_name] =>
[weight] => 487.99
[form] => C23H30ClN7O3
[cas] => 2520113-69-1
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(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-((1,4,5,6-tetrahydropyrimidin-2-yl)methyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441005
Molecular Formula : C23H30ClN7O3
Molecular Weight : 487.99
stdClass Object
(
[pname] => (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
[catalogue_number] => PA 28 0441006
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[chemical_name] =>
[weight] => 576.06
[form] => C28H30ClN9O3
[cas] => NA
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(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441006
Molecular Formula : C28H30ClN9O3
Molecular Weight : 576.06
stdClass Object
(
[pname] => (R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
[catalogue_number] => PA 28 0441007
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[weight] => 449.52
[form] => C23H27N7O3
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(R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441007
Molecular Formula : C23H27N7O3
Molecular Weight : 449.52
stdClass Object
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[pname] => 1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
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1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441008
Molecular Formula : C24H24ClN7O4
Molecular Weight : 509.95
stdClass Object
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[catalogue_number] => PA 28 0441009
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[weight] => 767.67
[form] => C36H40Cl2N8O7
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4-((3-Chloro-4-methoxybenzyl)amino)-2-((S)-2-(((4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carbonyl)oxy)methyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
Catalogue No.:PA 28 0441009
Molecular Formula : C36H40Cl2N8O7
Molecular Weight : 767.67
stdClass Object
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[pname] => (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide
[catalogue_number] => PA 28 0441010
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[weight] => 519.04
[form] => C25H35ClN6O4
[cas] => 2520114-17-2
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(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441010
Molecular Formula : C25H35ClN6O4
Molecular Weight : 519.04
stdClass Object
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[weight] => 455.34
[form] => C20H24Cl2N4O4
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Ethyl (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441011
Molecular Formula : C20H24Cl2N4O4
Molecular Weight : 455.34
stdClass Object
(
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[catalogue_number] => PA 28 0441012
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[weight] => 427.28
[form] => C18H20Cl2N4O4
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(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
Catalogue No.:PA 28 0441012
Molecular Formula : C18H20Cl2N4O4
Molecular Weight : 427.28
stdClass Object
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[weight] => 420.89
[form] => C20H25ClN4O4
[cas] => 2520114-28-5
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Ethyl (S)-4-((2-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441013
Molecular Formula : C20H25ClN4O4
Molecular Weight : 420.89
stdClass Object
(
[pname] => 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
[catalogue_number] => PA 28 0441014
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[weight] => 446.91
[form] => C19H19ClN6O3S
[cas] => 1364671-52-2
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4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441014
Molecular Formula : C19H19ClN6O3S
Molecular Weight : 446.91
stdClass Object
(
[pname] => Avanafil D4
[catalogue_number] => PA STI 089027
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[chemical_name] =>
[weight] => 487.98
[form] => C23H22D4ClN7O3
[cas] => 2012598-68-2
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Catalogue No.:PA STI 089027
Molecular Formula : C23H22D4ClN7O3
Molecular Weight : 487.98
stdClass Object
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[pname] => Avanafil Diamine Impurity
[catalogue_number] => PA 28 0441015
[category_ids] => ,75,76,78,70,82,
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[weight] => 554.43
[form] => C26H25Cl2N7O3
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Avanafil Diamine Impurity
Catalogue No.:PA 28 0441015
Molecular Formula : C26H25Cl2N7O3
Molecular Weight : 554.43
stdClass Object
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[catalogue_number] => PA 28 0441016
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[weight] => 242.52
[form] => C8H10Cl3NO
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(3,5-Dichloro-4-methoxyphenyl)methanamine Hydrochloride
Catalogue No.:PA 28 0441016
Molecular Formula : C8H10Cl3NO
Molecular Weight : 242.52
stdClass Object
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[weight] => 392.84
[form] => C18H21ClN4O4
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(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid
Catalogue No.:PA 28 0441017
Molecular Formula : C18H21ClN4O4
Molecular Weight : 392.84
stdClass Object
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[weight] => 512.96
[form] => C23H25ClN8O4
[cas] => 3050754-67-8
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(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441019
Molecular Formula : C23H25ClN8O4
Molecular Weight : 512.96
stdClass Object
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[pname] => (1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
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[weight] => 858.78
[form] => C41H45Cl2N11O6
[cas] => NA
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(1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441020
Molecular Formula : C41H45Cl2N11O6
Molecular Weight : 858.78
stdClass Object
(
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[weight] => 420.85
[form] => C18H21ClN6O4
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(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441021
Molecular Formula : C18H21ClN6O4
Molecular Weight : 420.85
stdClass Object
(
[pname] => 4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
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[weight] => 459.91
[form] => C19H18ClN7O3S
[cas] => NA
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4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441022
Molecular Formula : C19H18ClN7O3S
Molecular Weight : 459.91
stdClass Object
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[weight] => 449.89
[form] => C20H24ClN5O5
[cas] => NA
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Ethyl (S)-4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441023
Molecular Formula : C20H24ClN5O5
Molecular Weight : 449.89
stdClass Object
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[weight] => 887.78
[form] => C41H44Cl2N12O7
[cas] => NA
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((S)-1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441024
Molecular Formula : C41H44Cl2N12O7
Molecular Weight : 887.78
stdClass Object
(
[pname] => ((S)-1-(4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
[catalogue_number] => PA 28 0441025
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((S)-1-(4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441025
Molecular Formula : C41H44Cl2N12O7
Molecular Weight : 887.78
stdClass Object
(
[pname] => Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)pyrimidine-5-carboxylate
[catalogue_number] => PA 28 0441026
[category_ids] => ,69,71,78,70,82,162,
[chemical_name] =>
[weight] => 396.85
[form] => C16H17ClN4O4S
[cas] => NA
[pslug] => ethyl-4-3-chloro-4-methoxybenzyl-nitroso-amino-2-methylthio-pyrimidine-5-carboxylate-pa280441026
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Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441026
Molecular Formula : C16H17ClN4O4S
Molecular Weight : 396.85
stdClass Object
(
[pname] => Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
[catalogue_number] => PA 28 0441027
[category_ids] => ,69,71,78,70,82,162,
[chemical_name] =>
[weight] => 412.85
[form] => C16H17ClN4O5S
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Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441027
Molecular Formula : C16H17ClN4O5S
Molecular Weight : 412.85
