Avatrombopag-impurities | Pharmaffiliates

Avatrombopag

Avatrombopag, sold under the brand name Doptelet, is a medication that used for certain conditions.lead to thrombocytopenia (low platelets) such as thrombocytopenia associated with chronic liver disease. Reference standards of Avatrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Avatrombopag -API
    [catalogue_number] => PA 01 2990000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 649.65
    [form] => C29H34Cl2N6O3S2
    [cas] => 570406-98-3
    [pslug] => 570406-98-3-avatrombopag-api-pa012990000
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PA 01 2990000

Avatrombopag -API


  • Catalogue No.:PA 01 2990000

  • CAS :

    570406-98-3

  • Molecular Formula : C29H34Cl2N6O3S2

  • Molecular Weight : 649.65

stdClass Object
(
    [pname] => 1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid
    [catalogue_number] => PA STI 088916
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 657.7
    [form] => C29H26D8Cl2N6O3S2
    [cas] => NA
    [pslug] => 1-3-chloro-5-4-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-2-2-3-3-5-5-6-6-d8-thiazol-2-yl-carbamoyl-pyridin-2-yl-piperidine-4-carboxylic-acid-pasti088916
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PA STI 088916

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid


  • Catalogue No.:PA STI 088916

  • CAS :

    NA

  • Molecular Formula : C29H26D8Cl2N6O3S2

  • Molecular Weight : 657.7

stdClass Object
(
    [pname] => 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid
    [catalogue_number] => PA 01 2991000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 284.7
    [form] => C12H13ClN2O4
    [cas] => 958457-83-5
    [pslug] => 958457-83-5-6-4-carboxypiperidin-1-yl-5-chloronicotinic-acid-pa012991000
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PA 01 2991000

6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid


  • Catalogue No.:PA 01 2991000

  • CAS :

    958457-83-5

  • Molecular Formula : C12H13ClN2O4

  • Molecular Weight : 284.7

stdClass Object
(
    [pname] => 1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic Acid
    [catalogue_number] => PA 01 2991001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 728.55
    [form] => C29H33BrCl2N6O3S2
    [cas] => NA
    [pslug] => 1-5-4-5-bromo-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-thiazol-2-yl-carbamoyl-3-chloropyridin-2-yl-piperidine-4-carboxylic-acid-pa012991001
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PA 01 2991001

1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic Acid


  • Catalogue No.:PA 01 2991001

  • CAS :

    NA

  • Molecular Formula : C29H33BrCl2N6O3S2

  • Molecular Weight : 728.55

stdClass Object
(
    [pname] => 5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine
    [catalogue_number] => PA 01 2991002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 374.49
    [form] => C7H3Br2ClN2S2
    [cas] => 2401867-89-6
    [pslug] => 2401867-89-6-5-bromo-4-5-bromo-4-chlorothiophen-2-yl-thiazol-2-amine-pa012991002
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PA 01 2991002

5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine


  • Catalogue No.:PA 01 2991002

  • CAS :

    2401867-89-6

  • Molecular Formula : C7H3Br2ClN2S2

  • Molecular Weight : 374.49

stdClass Object
(
    [pname] => 4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine
    [catalogue_number] => PA 01 2991003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 295.6
    [form] => C7H4BrClN2S2
    [cas] => 1534575-19-3
    [pslug] => 1534575-19-3-4-5-bromo-4-chlorothiophen-2-yl-thiazol-2-amine-pa012991003
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PA 01 2991003

4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine


  • Catalogue No.:PA 01 2991003

  • CAS :

    1534575-19-3

  • Molecular Formula : C7H4BrClN2S2

  • Molecular Weight : 295.6

stdClass Object
(
    [pname] => 5-Bromo-4-(thiophen-2-yl)thiazol-2-amine
    [catalogue_number] => PA 01 2991004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 261.16
    [form] => C7H5BrN2S2
    [cas] => 81216-84-4
    [pslug] => 81216-84-4-5-bromo-4-thiophen-2-yl-thiazol-2-amine-pa012991004
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PA 01 2991004

5-Bromo-4-(thiophen-2-yl)thiazol-2-amine


  • Catalogue No.:PA 01 2991004

  • CAS :

    81216-84-4

  • Molecular Formula : C7H5BrN2S2

  • Molecular Weight : 261.16

stdClass Object
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    [pname] => 5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine
    [catalogue_number] => PA 01 2991005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 295.6
    [form] => C7H4BrClN2S2
    [cas] => 1268118-96-2
    [pslug] => 1268118-96-2-5-bromo-4-5-chlorothiophen-2-yl-thiazol-2-amine-pa012991005
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PA 01 2991005

5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine


  • Catalogue No.:PA 01 2991005

  • CAS :

    1268118-96-2

  • Molecular Formula : C7H4BrClN2S2

  • Molecular Weight : 295.6

stdClass Object
(
    [pname] => 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine
    [catalogue_number] => PA 01 2991006
    [category_ids] => ,75,76,78,70,82,123,81,
    [chemical_name] => 
    [weight] => 216.7
    [form] => C7H5ClN2S2
    [cas] => 123971-45-9
    [pslug] => 123971-45-9-4-5-chloro-2-thienyl-1-3-thiazol-2-amine-pa012991006
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PA 01 2991006

4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine


  • Catalogue No.:PA 01 2991006

  • CAS :

    123971-45-9

  • Molecular Formula : C7H5ClN2S2

  • Molecular Weight : 216.7

stdClass Object
(
    [pname] => 4-(Thiophen-2-yl)thiazol-2-amine
    [catalogue_number] => PA 01 2991007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 182.26
    [form] => C7H6N2S2
    [cas] => 28989-50-6
    [pslug] => 28989-50-6-4-thiophen-2-yl-thiazol-2-amine-pa012991007
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PA 01 2991007

4-(Thiophen-2-yl)thiazol-2-amine


  • Catalogue No.:PA 01 2991007

  • CAS :

    28989-50-6

  • Molecular Formula : C7H6N2S2

  • Molecular Weight : 182.26

stdClass Object
(
    [pname] => 4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide
    [catalogue_number] => PA 01 2991013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 665.65
    [form] => C29H34Cl2N6O4S2
    [cas] => 2681355-40-6
    [pslug] => 2681355-40-6-4-2-6-4-carboxypiperidin-1-yl-5-chloronicotinamido-4-4-chlorothiophen-2-yl-thiazol-5-yl-1-cyclohexylpiperazine-1-oxide-pa012991013
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PA 01 2991013

4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide


  • Catalogue No.:PA 01 2991013

  • CAS :

    2681355-40-6

  • Molecular Formula : C29H34Cl2N6O4S2

  • Molecular Weight : 665.65

stdClass Object
(
    [pname] => 5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide
    [catalogue_number] => PA 01 2991008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 565.58
    [form] => C25H30Cl2N6OS2
    [cas] => 2626934-45-8
    [pslug] => 2626934-45-8-5-chloro-n-4-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-thiazol-2-yl-6-dimethylamino-nicotinamide-pa012991008
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PA 01 2991008

5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide


  • Catalogue No.:PA 01 2991008

  • CAS :

    2626934-45-8

  • Molecular Formula : C25H30Cl2N6OS2

  • Molecular Weight : 565.58

stdClass Object
(
    [pname] => 4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
    [catalogue_number] => PA 01 2991009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 382.97
    [form] => C17H23ClN4S2
    [cas] => 570407-64-6
    [pslug] => 570407-64-6-4-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-thiazol-2-amine-pa012991009
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PA 01 2991009

4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine


  • Catalogue No.:PA 01 2991009

  • CAS :

    570407-64-6

  • Molecular Formula : C17H23ClN4S2

  • Molecular Weight : 382.97

stdClass Object
(
    [pname] => Avatrombopag Ester Impurity
    [catalogue_number] => PA 01 2991010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 677.7
    [form] => C31H38Cl2N6O3S2
    [cas] => 570403-14-4
    [pslug] => 570403-14-4-avatrombopag-ester-impurity-pa012991010
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PA 01 2991010

Avatrombopag Ester Impurity


  • Catalogue No.:PA 01 2991010

  • CAS :

    570403-14-4

  • Molecular Formula : C31H38Cl2N6O3S2

  • Molecular Weight : 677.7

stdClass Object
(
    [pname] => Ethyl 1-ethylpiperidine-4-carboxylate
    [catalogue_number] => PA 01 2991011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 185.27
    [form] => C10H19NO2
    [cas] => 24252-38-8
    [pslug] => 24252-38-8-ethyl-1-ethylpiperidine-4-carboxylate-pa012991011
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PA 01 2991011

Ethyl 1-ethylpiperidine-4-carboxylate


  • Catalogue No.:PA 01 2991011

  • CAS :

    24252-38-8

  • Molecular Formula : C10H19NO2

  • Molecular Weight : 185.27

stdClass Object
(
    [pname] => 5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide
    [catalogue_number] => PA 01 2991012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 556.95
    [form] => C23H24Cl3N5OS2
    [cas] => 570403-04-2
    [pslug] => 570403-04-2-5-6-dichloro-n-4-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-thiazol-2-yl-nicotinamide-pa012991012
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PA 01 2991012

5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide


  • Catalogue No.:PA 01 2991012

  • CAS :

    570403-04-2

  • Molecular Formula : C23H24Cl3N5OS2

  • Molecular Weight : 556.95