bosentan
Bosentan is used to treat people with moderate pulmonary arterial hypertension and to reduce the number of digital ulcers. It is available as film-coated tablets or as dispersable tablets for oral suspension.. Reference standards of Bosentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
(
[pname] => Bosentan
[catalogue_number] => PA 29 13000
[category_ids] => ,80,71,85,83,78,70,82,88,
[chemical_name] =>
[weight] => 551.61
[form] => C27H29N5O6S
[cas] => 147536-97-8
[pslug] => 147536-97-8-bosentan-api-pa2913000
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Catalogue No.:PA 29 13000
Molecular Formula : C27H29N5O6S
Molecular Weight : 551.61
stdClass Object
(
[pname] => Bosentan-d4
[catalogue_number] => PA STI 014260
[category_ids] => ,80,71,85,83,78,70,82,88,98,
[chemical_name] =>
[weight] => 555.64
[form] => C27H25D4N5O6S
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Catalogue No.:PA STI 014260
Molecular Formula : C27H25D4N5O6S
Molecular Weight : 555.64
stdClass Object
(
[pname] => Bosentan-13C2, d4
[catalogue_number] => PA STI 014270
[category_ids] => ,80,71,85,83,78,70,82,88,98,
[chemical_name] =>
[weight] => 557.62
[form] => C2513C2H25D4N5O6S
[cas] => NA
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Catalogue No.:PA STI 014270
Molecular Formula : C2513C2H25D4N5O6S
Molecular Weight : 557.62
stdClass Object
(
[pname] => Desmethyl Bosentan-d4
[catalogue_number] => PA STI 028100
[category_ids] => ,70,75,76,78,82,83,85,88,98,
[chemical_name] =>
[weight] => 541.61
[form] => C26H23D4N5O6S
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Catalogue No.:PA STI 028100
Molecular Formula : C26H23D4N5O6S
Molecular Weight : 541.61
stdClass Object
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[pname] => Hydroxy Bosentan-d4
[catalogue_number] => PA STI 047970
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[weight] => 571.64
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Catalogue No.:PA STI 047970
Molecular Formula : C27H25D4N5O7S
Molecular Weight : 571.64
stdClass Object
(
[pname] => Hydroxy Bosentan-d6
[catalogue_number] => PA STI 047980
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[weight] => 573.65
[form] => C27H23D6N5O7S
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Catalogue No.:PA STI 047980
Molecular Formula : C27H23D6N5O7S
Molecular Weight : 573.65
stdClass Object
(
[pname] => Hydroxy Desmethyl Bosentan-d4
[catalogue_number] => PA STI 048560
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Hydroxy Desmethyl Bosentan-d4
Catalogue No.:PA STI 048560
Molecular Formula : C26H23D4N5O7S
Molecular Weight : 557.61
stdClass Object
(
[pname] => Bosentan sulfide
[catalogue_number] => PA 29 0131002
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[weight] => 519.62
[form] => C27H29N5O4S
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Catalogue No.:PA 29 0131002
Molecular Formula : C27H29N5O4S
Molecular Weight : 519.62
stdClass Object
(
[pname] => Bosentan sulfoxide
[catalogue_number] => PA 29 0131003
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[weight] => 535.62
[form] => C27H29N5O5S
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Catalogue No.:PA 29 0131003
Molecular Formula : C27H29N5O5S
Molecular Weight : 535.62
stdClass Object
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[pname] => 4-(Tert-butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
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4-(Tert-butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
Catalogue No.:PA 29 0131004
Molecular Formula : C22H27N5O6S
Molecular Weight : 489.55
stdClass Object
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[pname] => Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]-
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Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]-
Catalogue No.:PA 29 0131005
Molecular Formula : C20H21N5O4S
Molecular Weight : 427.48
stdClass Object
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[catalogue_number] => PA 29 0131006
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[weight] => 311.3
[form] => C15H13N5O3
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6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-ol
stdClass Object
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[catalogue_number] => PA 29 0131007
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[weight] => 355.35
[form] => C17H17N5O4
[cas] => 174227-27-1
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2-((6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol
Catalogue No.:PA 29 0131007
Molecular Formula : C17H17N5O4
Molecular Weight : 355.35
stdClass Object
(
[pname] => Isopropyl 4-(tert-butyl)benzenesulfonate
[catalogue_number] => PA 29 0131008
[category_ids] => ,78,70,82,
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[weight] => 256.36
[form] => C13H20O3S
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Isopropyl 4-(tert-butyl)benzenesulfonate
Catalogue No.:PA 29 0131008
Molecular Formula : C13H20O3S
Molecular Weight : 256.36
stdClass Object
(
[pname] => 2-Hydroxyethyl 4-(tert-butyl)benzenesulfonate
[catalogue_number] => PA 29 0131009
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[weight] => 258.33
[form] => C12H18O4S
[cas] => 1413393-94-8
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2-Hydroxyethyl 4-(tert-butyl)benzenesulfonate
Catalogue No.:PA 29 0131009
Molecular Formula : C12H18O4S
Molecular Weight : 258.33
stdClass Object
(
[pname] => 4-(tert-Butyl)benzenesulfonohydrazide
[catalogue_number] => PAI 29 013001
[category_ids] => ,70,
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[weight] => 228.31
[form] => C10H16N2O2S
[cas] => 65604-75-3
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4-(tert-Butyl)benzenesulfonohydrazide
Catalogue No.:PAI 29 013001
Molecular Formula : C10H16N2O2S
Molecular Weight : 228.31
stdClass Object
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[catalogue_number] => PA 29 0131010
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[weight] => 374.78
[form] => C17H15ClN4O4
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2-((6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol
Catalogue No.:PA 29 0131010
Molecular Formula : C17H15ClN4O4
Molecular Weight : 374.78
stdClass Object
(
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[catalogue_number] => PAI 29 013002
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[weight] => 266.29
[form] => C14H18O5
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Diethyl 2-(benzyloxy)malonate
Catalogue No.:PAI 29 013002
Molecular Formula : C14H18O5
Molecular Weight : 266.29
stdClass Object
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[catalogue_number] => PAI 29 013003
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[weight] => 146.19
[form] => C7H14O3
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2-((Tetrahydro-2H-pyran-2-yl)oxy)ethan-1-ol
Catalogue No.:PAI 29 013003
Molecular Formula : C7H14O3
Molecular Weight : 146.19
stdClass Object
(
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[catalogue_number] => PAI 29 013004
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[chemical_name] =>
[weight] => 190.24
[form] => C9H18O4
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2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethan-1-ol
Catalogue No.:PAI 29 013004
Molecular Formula : C9H18O4
Molecular Weight : 190.24
stdClass Object
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[catalogue_number] => PAI 29 013005
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[chemical_name] =>
[weight] => 232.72
[form] => C10H13ClO2S
[cas] => 57877-28-8
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2-(tert-Butyl)benzenesulfonyl Chloride
Catalogue No.:PAI 29 013005
Molecular Formula : C10H13ClO2S
Molecular Weight : 232.72
stdClass Object
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[weight] => 329.74
[form] => C15H12ClN5O2
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6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-amine
Catalogue No.:PAI 29 013006
Molecular Formula : C15H12ClN5O2
Molecular Weight : 329.74
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[catalogue_number] => PAI 29 013007
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[weight] => 330.55
[form] => C20H26S2
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1,2-Bis(4-(tert-butyl)phenyl)disulfane
Catalogue No.:PAI 29 013007
Molecular Formula : C20H26S2
Molecular Weight : 330.55
stdClass Object
(
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[weight] => 642.46
[form] => C30H21Cl2N9O4
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bis(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amine
Catalogue No.:PAI 29 013008
Molecular Formula : C30H21Cl2N9O4
Molecular Weight : 642.46
stdClass Object
(
[pname] => 4-Isopropylbenzenesulfonamide
[catalogue_number] => PAI 29 013009
[category_ids] => ,70,
[chemical_name] =>
[weight] => 199.27
[form] => C9H13NO2S
[cas] => 6335-39-3
[pslug] => 6335-39-3-4-isopropylbenzenesulfonamide-pai29013009
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4-Isopropylbenzenesulfonamide
Catalogue No.:PAI 29 013009
Molecular Formula : C9H13NO2S
Molecular Weight : 199.27
stdClass Object
(
[pname] => N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide
[catalogue_number] => PAI 29 013010
[category_ids] => ,70,
[chemical_name] =>
[weight] => 511.98
[form] => C24H22ClN5O4S
[cas] => 1268612-25-4
[pslug] => 1268612-25-4-n-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-4-isopropylbenzenesulfonamide-pai29013010
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N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide
Catalogue No.:PAI 29 013010
Molecular Formula : C24H22ClN5O4S
Molecular Weight : 511.98
stdClass Object
(
[pname] => 4-(tert-Butyl)benzenesulfinic Chloride
[catalogue_number] => PAI 29 013011
[category_ids] => ,70,
[chemical_name] =>
[weight] => 216.72
[form] => C10H13ClOS
[cas] => 64790-77-8
[pslug] => 64790-77-8-4-tert-butyl-benzenesulfinic-chloride-pai29013011
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4-(tert-Butyl)benzenesulfinic Chloride
Catalogue No.:PAI 29 013011
Molecular Formula : C10H13ClOS
Molecular Weight : 216.72
stdClass Object
(
[pname] => 4-Chloro-5-(2-methoxyphenoxy)-6-(vinyloxy)-2,2'-bipyrimidine
[catalogue_number] => PAI 29 013012
[category_ids] => ,70,
[chemical_name] =>
[weight] => 356.77
[form] => C17H13ClN4O3
[cas] => NA
[pslug] => 4-chloro-5-2-methoxyphenoxy-6-vinyloxy-2-2-bipyrimidine-pai29013012
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4-Chloro-5-(2-methoxyphenoxy)-6-(vinyloxy)-2,2'-bipyrimidine
Catalogue No.:PAI 29 013012
Molecular Formula : C17H13ClN4O3
Molecular Weight : 356.77
stdClass Object
(
[pname] => 6-Hydroxy-5-methoxy-[2,2'-bipyrimidin]-4(3H)-one
[catalogue_number] => PAI 29 013013
[category_ids] => ,70,
[chemical_name] =>
[weight] => 220.19
[form] => C9H8N4O3
[cas] => NA
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6-Hydroxy-5-methoxy-[2,2'-bipyrimidin]-4(3H)-one
Catalogue No.:PAI 29 013013
Molecular Formula : C9H8N4O3
Molecular Weight : 220.19
stdClass Object
(
[pname] => Diethyl 2-methoxymalonate
[catalogue_number] => PAI 29 013014
[category_ids] => ,70,
[chemical_name] =>
[weight] => 190.2
[form] => C8H14O5
[cas] => 40924-27-4
[pslug] => 40924-27-4-diethyl-2-methoxymalonate-pai29013014
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Diethyl 2-methoxymalonate
stdClass Object
(
[pname] => 4,6-Dichloro-5-methoxy-1,6-dihydro-2,2'-bipyrimidine
[catalogue_number] => PAI 29 013015
[category_ids] => ,70,
[chemical_name] =>
[weight] => 259.09
[form] => C9H8Cl2N4O
[cas] => NA
[pslug] => 4-6-dichloro-5-methoxy-1-6-dihydro-2-2-bipyrimidine-pai29013015
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4,6-Dichloro-5-methoxy-1,6-dihydro-2,2'-bipyrimidine
Catalogue No.:PAI 29 013015
Molecular Formula : C9H8Cl2N4O
Molecular Weight : 259.09
stdClass Object
(
[pname] => 2-Propoxyethyl 4-methylbenzenesulfonate
[catalogue_number] => PA 29 0131012
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 258.33
[form] => C12H18O4S
[cas] => 52497-47-9
[pslug] => 52497-47-9-2-propoxyethyl-4-methylbenzenesulfonate-pa290131012
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2-Propoxyethyl 4-methylbenzenesulfonate
Catalogue No.:PA 29 0131012
Molecular Formula : C12H18O4S
Molecular Weight : 258.33
stdClass Object
(
[pname] => 3-Ethoxypropyl 4-methylbenzenesulfonate
[catalogue_number] => PA 29 0131011
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 258.33
[form] => C12H18O4S
[cas] => 91766-05-1
[pslug] => 91766-05-1-3-ethoxypropyl-4-methylbenzenesulfonate-pa290131011
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3-Ethoxypropyl 4-methylbenzenesulfonate
Catalogue No.:PA 29 0131011
Molecular Formula : C12H18O4S
Molecular Weight : 258.33
stdClass Object
(
[pname] => Ethyl 2-(4-(chlorosulfonyl)phenyl)-2-methylpropanoate
[catalogue_number] => PAI 29 013016
[category_ids] => ,70,
[chemical_name] =>
[weight] => 290.76
[form] => C12H15ClO4S
[cas] => 321565-78-0
[pslug] => 321565-78-0-ethyl-2-4-chlorosulfonyl-phenyl-2-methylpropanoate-pai29013016
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Ethyl 2-(4-(chlorosulfonyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 013016
Molecular Formula : C12H15ClO4S
Molecular Weight : 290.76
stdClass Object
(
[pname] => 4-(2-Methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
[catalogue_number] => PAI 29 013017
[category_ids] => ,70,
[chemical_name] =>
[weight] => 313.41
[form] => C15H23NO4S
[cas] => NA
[pslug] => 4-2-methyl-1-tetrahydro-2h-pyran-2-yl-oxy-propan-2-yl-benzenesulfonamide-pai29013017
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4-(2-Methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
Catalogue No.:PAI 29 013017
Molecular Formula : C15H23NO4S
Molecular Weight : 313.41
stdClass Object
(
[pname] => N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(2-methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
[catalogue_number] => PAI 29 013018
[category_ids] => ,70,
[chemical_name] =>
[weight] => 626.13
[form] => C30H32ClN5O6S
[cas] => NA
[pslug] => n-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-4-2-methyl-1-tetrahydro-2h-pyran-2-yl-oxy-propan-2-yl-benzenesulfonamide-pai29013018
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N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(2-methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
Catalogue No.:PAI 29 013018
Molecular Formula : C30H32ClN5O6S
Molecular Weight : 626.13
stdClass Object
(
[pname] => N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(2-methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
[catalogue_number] => PAI 29 013019
[category_ids] => ,70,
[chemical_name] =>
[weight] => 651.74
[form] => C32H37N5O8S
[cas] => NA
[pslug] => n-6-2-hydroxyethoxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-4-2-methyl-1-tetrahydro-2h-pyran-2-yl-oxy-propan-2-yl-benzenesulfonamide-pai29013019
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N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(2-methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
Catalogue No.:PAI 29 013019
Molecular Formula : C32H37N5O8S
Molecular Weight : 651.74
stdClass Object
(
[pname] => Ethyl 2-(4-(N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoate
[catalogue_number] => PAI 29 013020
[category_ids] => ,70,
[chemical_name] =>
[weight] => 584.04
[form] => C27H26ClN5O6S
[cas] => NA
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Ethyl 2-(4-(N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 013020
Molecular Formula : C27H26ClN5O6S
Molecular Weight : 584.04
stdClass Object
(
[pname] => Ethyl 2-(4-(N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoate
[catalogue_number] => PAI 29 013021
[category_ids] => ,70,
[chemical_name] =>
[weight] => 609.65
[form] => C29H31N5O8S
[cas] => NA
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Ethyl 2-(4-(N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 013021
Molecular Formula : C29H31N5O8S
Molecular Weight : 609.65
stdClass Object
(
[pname] => 2-(4-(N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoic Acid
[catalogue_number] => PAI 29 013022
[category_ids] => ,70,
[chemical_name] =>
[weight] => 581.6
[form] => C27H27N5O8S
[cas] => NA
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2-(4-(N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoic Acid
stdClass Object
(
[pname] => 6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one
[catalogue_number] => PA 29 0131013
[category_ids] => ,80,71,85,83,78,70,82,88,
[chemical_name] =>
[weight] => 356.34
[form] => C17H16N4O5
[cas] => 1359829-87-0
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6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one
Catalogue No.:PA 29 0131013
Molecular Formula : C17H16N4O5
Molecular Weight : 356.34
stdClass Object
(
[pname] => 4-(tert-Butyl)-N-(6-(2-chloroethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
[catalogue_number] => PA 29 0131014
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 570.06
[form] => C27H28ClN5O5S
[cas] => 1855932-53-4
[pslug] => 1855932-53-4-4-tert-butyl-n-6-2-chloroethoxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-benzenesulfonamide-pa290131014
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4-(tert-Butyl)-N-(6-(2-chloroethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
Catalogue No.:PA 29 0131014
Molecular Formula : C27H28ClN5O5S
Molecular Weight : 570.06
