Bosentan-impurities | Pharmaffiliates

bosentan

Bosentan is used to treat people with moderate pulmonary arterial hypertension and to reduce the number of digital ulcers. It is available as film-coated tablets or as dispersable tablets for oral suspension.. Reference standards of Bosentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [pname] => Bosentan - API Standards 
    [catalogue_number] => PA 29 13000
    [category_ids] => ,80,71,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 551.61
    [form] => C27H29N5O6S
    [cas] => 147536-97-8
    [pslug] => 147536-97-8-bosentan-api-pa2913000
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PA 29 13000

Bosentan - API Standards


  • Catalogue No.:PA 29 13000

  • CAS :

    147536-97-8

  • Molecular Formula : C27H29N5O6S

  • Molecular Weight : 551.61

stdClass Object
(
    [pname] => Bosentan-d4
    [catalogue_number] => PA STI 014260
    [category_ids] => ,80,71,85,83,78,70,82,88,98,
    [chemical_name] => 
    [weight] => 555.64
    [form] => C27H25D4N5O6S
    [cas] => 1065472-77-6
    [pslug] => 1065472-77-6-bosentan-d4-pasti014260
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PA STI 014260

Bosentan-d4


  • Catalogue No.:PA STI 014260

  • CAS :

    1065472-77-6

  • Molecular Formula : C27H25D4N5O6S

  • Molecular Weight : 555.64

stdClass Object
(
    [pname] => Bosentan-13C2, d4
    [catalogue_number] => PA STI 014270
    [category_ids] => ,80,71,85,83,78,70,82,88,98,
    [chemical_name] => 
    [weight] => 557.62
    [form] => C2513C2H25D4N5O6S
    [cas] => NA
    [pslug] => bosentan-13c2-d4-pasti014270
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PA STI 014270

Bosentan-13C2, d4


  • Catalogue No.:PA STI 014270

  • CAS :

    NA

  • Molecular Formula : C2513C2H25D4N5O6S

  • Molecular Weight : 557.62

stdClass Object
(
    [pname] => Desmethyl Bosentan-d4
    [catalogue_number] => PA STI 028100
    [category_ids] => ,70,75,76,78,82,83,85,88,98,
    [chemical_name] => 
    [weight] => 541.61
    [form] => C26H23D4N5O6S
    [cas] => 2748567-59-9
    [pslug] => 2748567-59-9-desmethyl-bosentan-d4-pasti028100
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PA STI 028100

Desmethyl Bosentan-d4


  • Catalogue No.:PA STI 028100

  • CAS :

    2748567-59-9

  • Molecular Formula : C26H23D4N5O6S

  • Molecular Weight : 541.61

stdClass Object
(
    [pname] => Hydroxy Bosentan-d4
    [catalogue_number] => PA STI 047970
    [category_ids] => ,80,71,98,76,75,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 571.64
    [form] => C27H25D4N5O7S
    [cas] => 1065472-91-4
    [pslug] => 1065472-91-4-hydroxy-bosentan-d4-pasti047970
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PA STI 047970

Hydroxy Bosentan-d4


  • Catalogue No.:PA STI 047970

  • CAS :

    1065472-91-4

  • Molecular Formula : C27H25D4N5O7S

  • Molecular Weight : 571.64

stdClass Object
(
    [pname] => Hydroxy Bosentan-d6
    [catalogue_number] => PA STI 047980
    [category_ids] => ,80,71,98,76,75,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 573.65
    [form] => C27H23D6N5O7S
    [cas] => 1246817-57-1
    [pslug] => 1246817-57-1-hydroxy-bosentan-d6-pasti047980
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PA STI 047980

Hydroxy Bosentan-d6


  • Catalogue No.:PA STI 047980

  • CAS :

    1246817-57-1

  • Molecular Formula : C27H23D6N5O7S

  • Molecular Weight : 573.65

stdClass Object
(
    [pname] => Hydroxy Desmethyl Bosentan-d4
    [catalogue_number] => PA STI 048560
    [category_ids] => ,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 557.61
    [form] => C26H23D4N5O7S
    [cas] => NA
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PA STI 048560

Hydroxy Desmethyl Bosentan-d4


  • Catalogue No.:PA STI 048560

  • CAS :

    NA

  • Molecular Formula : C26H23D4N5O7S

  • Molecular Weight : 557.61

stdClass Object
(
    [pname] => Potassium ((4-(tert-butyl)phenyl)sulfonyl)(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amide
    [catalogue_number] => PA 29 0131001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 589.71
    [form] => C27H28KN5O6S
    [cas] => 1174918-31-0
    [pslug] => 1174918-31-0-potassium-4-tert-butyl-phenyl-sulfonyl-6-2-hydroxyethoxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-amide-pa290131001
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PA 29 0131001

Potassium ((4-(tert-butyl)phenyl)sulfonyl)(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amide


  • Catalogue No.:PA 29 0131001

  • CAS :

    1174918-31-0

  • Molecular Formula : C27H28KN5O6S

  • Molecular Weight : 589.71

stdClass Object
(
    [pname] => Bosentan sulfide
    [catalogue_number] => PA 29 0131002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 519.62
    [form] =>  C27H29N5O4S
    [cas] => NA
    [pslug] => bosentan-sulfide-pa290131002
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PA 29 0131002

Bosentan sulfide


  • Catalogue No.:PA 29 0131002

  • CAS :

    NA

  • Molecular Formula : C27H29N5O4S

  • Molecular Weight : 519.62

stdClass Object
(
    [pname] => Bosentan sulfoxide
    [catalogue_number] => PA 29 0131003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 535.62
    [form] => C27H29N5O5S
    [cas] => NA
    [pslug] => bosentan-sulfoxide-pa290131003
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PA 29 0131003

Bosentan sulfoxide


  • Catalogue No.:PA 29 0131003

  • CAS :

    NA

  • Molecular Formula : C27H29N5O5S

  • Molecular Weight : 535.62

stdClass Object
(
    [pname] => 4-(Tert-butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
    [catalogue_number] => PA 29 0131004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 489.55
    [form] => C22H27N5O6S
    [cas] => 1257099-41-4
    [pslug] => 1257099-41-4-4-tert-butyl-n-5-hydroxy-6-2-2-hydroxyethoxy-ethoxy-2-2-bipyrimidin-4-yl-benzenesulfonamide-pa290131004
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PA 29 0131004

4-(Tert-butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 29 0131004

  • CAS :

    1257099-41-4

  • Molecular Formula : C22H27N5O6S

  • Molecular Weight : 489.55

stdClass Object
(
    [pname] => Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]-
    [catalogue_number] => PA 29 0131005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 427.48
    [form] => C20H21N5O4S
    [cas] => 1257099-42-5
    [pslug] => 1257099-42-5-benzenesulfonamide-4-1-1-dimethylethyl-n-6-ethenyloxy-5-hydroxy-2-2-bipyrimidin-4-yl-pa290131005
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PA 29 0131005

Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]-


  • Catalogue No.:PA 29 0131005

  • CAS :

    1257099-42-5

  • Molecular Formula : C20H21N5O4S

  • Molecular Weight : 427.48

stdClass Object
(
    [pname] => 6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-ol
    [catalogue_number] => PA 29 0131006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 311.3
    [form] => C15H13N5O3
    [cas] => NA
    [pslug] => 6-amino-5-2-methoxyphenoxy-2-2-bipyrimidin-4-ol-pa290131006
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PA 29 0131006

6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-ol


  • Catalogue No.:PA 29 0131006

  • CAS :

    NA

  • Molecular Formula : C15H13N5O3

  • Molecular Weight : 311.3

stdClass Object
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    [pname] => 2-((6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol
    [catalogue_number] => PA 29 0131007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 355.35
    [form] => C17H17N5O4
    [cas] => 174227-27-1
    [pslug] => 174227-27-1-2-6-amino-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-oxy-ethan-1-ol-pa290131007
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PA 29 0131007

2-((6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol


  • Catalogue No.:PA 29 0131007

  • CAS :

    174227-27-1

  • Molecular Formula : C17H17N5O4

  • Molecular Weight : 355.35

stdClass Object
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    [pname] => Isopropyl 4-(tert-butyl)benzenesulfonate
    [catalogue_number] => PA 29 0131008
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 256.36
    [form] => C13H20O3S
    [cas] => NA
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PA 29 0131008

Isopropyl 4-(tert-butyl)benzenesulfonate


  • Catalogue No.:PA 29 0131008

  • CAS :

    NA

  • Molecular Formula : C13H20O3S

  • Molecular Weight : 256.36

stdClass Object
(
    [pname] => 2-Hydroxyethyl 4-(tert-butyl)benzenesulfonate
    [catalogue_number] => PA 29 0131009
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 258.33
    [form] => C12H18O4S
    [cas] => 1413393-94-8
    [pslug] => 1413393-94-8-2-hydroxyethyl-4-tert-butyl-benzenesulfonate-pa290131009
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PA 29 0131009

2-Hydroxyethyl 4-(tert-butyl)benzenesulfonate


  • Catalogue No.:PA 29 0131009

  • CAS :

    1413393-94-8

  • Molecular Formula : C12H18O4S

  • Molecular Weight : 258.33

stdClass Object
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    [pname] => 4-(tert-Butyl)benzenesulfonohydrazide
    [catalogue_number] => PAI 29 013001
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 228.31
    [form] => C10H16N2O2S
    [cas] => 65604-75-3
    [pslug] => 65604-75-3-4-tert-butyl-benzenesulfonohydrazide-pai29013001
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PAI 29 013001

4-(tert-Butyl)benzenesulfonohydrazide


  • Catalogue No.:PAI 29 013001

  • CAS :

    65604-75-3

  • Molecular Formula : C10H16N2O2S

  • Molecular Weight : 228.31

stdClass Object
(
    [pname] =>  2-((6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol
    [catalogue_number] => PA 29 0131010
    [category_ids] => ,80,71,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 374.78
    [form] => C17H15ClN4O4
    [cas] => 184779-15-5
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PA 29 0131010

 2-((6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol


  • Catalogue No.:PA 29 0131010

  • CAS :

    184779-15-5

  • Molecular Formula : C17H15ClN4O4

  • Molecular Weight : 374.78

stdClass Object
(
    [pname] => Diethyl 2-(benzyloxy)malonate
    [catalogue_number] => PAI 29 013002
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 266.29
    [form] => C14H18O5
    [cas] => 5778-35-8
    [pslug] => 5778-35-8-diethyl-2-benzyloxy-malonate-pai29013002
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PAI 29 013002

Diethyl 2-(benzyloxy)malonate


  • Catalogue No.:PAI 29 013002

  • CAS :

    5778-35-8

  • Molecular Formula : C14H18O5

  • Molecular Weight : 266.29

stdClass Object
(
    [pname] => 2-((Tetrahydro-2H-pyran-2-yl)oxy)ethan-1-ol
    [catalogue_number] => PAI 29 013003
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 146.19
    [form] => C7H14O3
    [cas] => 2162-31-4
    [pslug] => 2162-31-4-2-tetrahydro-2h-pyran-2-yl-oxy-ethan-1-ol-pai29013003
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PAI 29 013003

2-((Tetrahydro-2H-pyran-2-yl)oxy)ethan-1-ol


  • Catalogue No.:PAI 29 013003

  • CAS :

    2162-31-4

  • Molecular Formula : C7H14O3

  • Molecular Weight : 146.19

stdClass Object
(
    [pname] => 2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethan-1-ol
    [catalogue_number] => PAI 29 013004
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 190.24
    [form] => C9H18O4
    [cas] => 2163-11-3
    [pslug] => 2163-11-3-2-2-tetrahydro-2h-pyran-2-yl-oxy-ethoxy-ethan-1-ol-pai29013004
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PAI 29 013004

2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethan-1-ol


  • Catalogue No.:PAI 29 013004

  • CAS :

    2163-11-3

  • Molecular Formula : C9H18O4

  • Molecular Weight : 190.24

stdClass Object
(
    [pname] => 2-(tert-Butyl)benzenesulfonyl Chloride
    [catalogue_number] => PAI 29 013005
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 232.72
    [form] => C10H13ClO2S
    [cas] => 57877-28-8
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PAI 29 013005

2-(tert-Butyl)benzenesulfonyl Chloride


  • Catalogue No.:PAI 29 013005

  • CAS :

    57877-28-8

  • Molecular Formula : C10H13ClO2S

  • Molecular Weight : 232.72

stdClass Object
(
    [pname] => 6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-amine
    [catalogue_number] => PAI 29 013006
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 329.74
    [form] => C15H12ClN5O2
    [cas] => 179400-82-9
    [pslug] => 179400-82-9-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-amine-pai29013006
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PAI 29 013006

6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-amine


  • Catalogue No.:PAI 29 013006

  • CAS :

    179400-82-9

  • Molecular Formula : C15H12ClN5O2

  • Molecular Weight : 329.74

stdClass Object
(
    [pname] => 1,2-Bis(4-(tert-butyl)phenyl)disulfane
    [catalogue_number] => PAI 29 013007
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 330.55
    [form] => C20H26S2
    [cas] => 7605-48-3
    [pslug] => 7605-48-3-1-2-bis-4-tert-butyl-phenyl-disulfane-pai29013007
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PAI 29 013007

1,2-Bis(4-(tert-butyl)phenyl)disulfane


  • Catalogue No.:PAI 29 013007

  • CAS :

    7605-48-3

  • Molecular Formula : C20H26S2

  • Molecular Weight : 330.55

stdClass Object
(
    [pname] => bis(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amine
    [catalogue_number] => PAI 29 013008
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 642.46
    [form] => C30H21Cl2N9O4
    [cas] => NA
    [pslug] => bis-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-amine-pai29013008
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PAI 29 013008

bis(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amine


  • Catalogue No.:PAI 29 013008

  • CAS :

    NA

  • Molecular Formula : C30H21Cl2N9O4

  • Molecular Weight : 642.46

stdClass Object
(
    [pname] => 4-Isopropylbenzenesulfonamide
    [catalogue_number] => PAI 29 013009
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 199.27
    [form] => C9H13NO2S
    [cas] => 6335-39-3
    [pslug] => 6335-39-3-4-isopropylbenzenesulfonamide-pai29013009
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PAI 29 013009

4-Isopropylbenzenesulfonamide


  • Catalogue No.:PAI 29 013009

  • CAS :

    6335-39-3

  • Molecular Formula : C9H13NO2S

  • Molecular Weight : 199.27

stdClass Object
(
    [pname] => N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide
    [catalogue_number] => PAI 29 013010
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 511.98
    [form] => C24H22ClN5O4S
    [cas] => 1268612-25-4
    [pslug] => 1268612-25-4-n-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-4-isopropylbenzenesulfonamide-pai29013010
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PAI 29 013010

N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide


  • Catalogue No.:PAI 29 013010

  • CAS :

    1268612-25-4

  • Molecular Formula : C24H22ClN5O4S

  • Molecular Weight : 511.98

stdClass Object
(
    [pname] => 4-(tert-Butyl)benzenesulfinic Chloride
    [catalogue_number] => PAI 29 013011
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 216.72
    [form] => C10H13ClOS
    [cas] => 64790-77-8
    [pslug] => 64790-77-8-4-tert-butyl-benzenesulfinic-chloride-pai29013011
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PAI 29 013011

4-(tert-Butyl)benzenesulfinic Chloride


  • Catalogue No.:PAI 29 013011

  • CAS :

    64790-77-8

  • Molecular Formula : C10H13ClOS

  • Molecular Weight : 216.72

stdClass Object
(
    [pname] => 4-Chloro-5-(2-methoxyphenoxy)-6-(vinyloxy)-2,2'-bipyrimidine
    [catalogue_number] => PAI 29 013012
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 356.77
    [form] => C17H13ClN4O3
    [cas] => NA
    [pslug] => 4-chloro-5-2-methoxyphenoxy-6-vinyloxy-2-2-bipyrimidine-pai29013012
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PAI 29 013012

4-Chloro-5-(2-methoxyphenoxy)-6-(vinyloxy)-2,2'-bipyrimidine


  • Catalogue No.:PAI 29 013012

  • CAS :

    NA

  • Molecular Formula : C17H13ClN4O3

  • Molecular Weight : 356.77

stdClass Object
(
    [pname] => 6-Hydroxy-5-methoxy-[2,2'-bipyrimidin]-4(3H)-one
    [catalogue_number] => PAI 29 013013
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 220.19
    [form] => C9H8N4O3
    [cas] => NA
    [pslug] => 6-hydroxy-5-methoxy-2-2-bipyrimidin-4-3h-one-pai29013013
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PAI 29 013013

6-Hydroxy-5-methoxy-[2,2'-bipyrimidin]-4(3H)-one


  • Catalogue No.:PAI 29 013013

  • CAS :

    NA

  • Molecular Formula : C9H8N4O3

  • Molecular Weight : 220.19

stdClass Object
(
    [pname] => Diethyl 2-methoxymalonate
    [catalogue_number] => PAI 29 013014
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 190.2
    [form] => C8H14O5
    [cas] => 40924-27-4
    [pslug] => 40924-27-4-diethyl-2-methoxymalonate-pai29013014
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PAI 29 013014

Diethyl 2-methoxymalonate


  • Catalogue No.:PAI 29 013014

  • CAS :

    40924-27-4

  • Molecular Formula : C8H14O5

  • Molecular Weight : 190.2

stdClass Object
(
    [pname] => 4,6-Dichloro-5-methoxy-1,6-dihydro-2,2'-bipyrimidine
    [catalogue_number] => PAI 29 013015
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 259.09
    [form] => C9H8Cl2N4O
    [cas] => NA
    [pslug] => 4-6-dichloro-5-methoxy-1-6-dihydro-2-2-bipyrimidine-pai29013015
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PAI 29 013015

4,6-Dichloro-5-methoxy-1,6-dihydro-2,2'-bipyrimidine


  • Catalogue No.:PAI 29 013015

  • CAS :

    NA

  • Molecular Formula : C9H8Cl2N4O

  • Molecular Weight : 259.09