ezetimibe
An anti-hyperlipidemic medication, it is used for cholesterol lowering that decreases the absorption of cholesterol in the small intestine. Ezetimibe is hence used for treating high cholesterol. Reference standards of Ezetimibe API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[catalogue_number] => PA 05 0411021
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[weight] => 357.38
[form] => C20H20FNO4
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(R)-3-((R)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
Catalogue No.:PA 05 0411021
Molecular Formula : C20H20FNO4
Molecular Weight : 357.38
stdClass Object
(
[pname] => Methyl 3-((2R,3R)-2-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoate
[catalogue_number] => PA 05 0411022
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[weight] => 433.48
[form] => C26H24FNO4
[cas] => 1607018-80-3
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Methyl 3-((2R,3R)-2-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoate
Catalogue No.:PA 05 0411022
Molecular Formula : C26H24FNO4
Molecular Weight : 433.48
stdClass Object
(
[pname] => (2R,3R,6S)-6-(4-Fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxylic Acid
[catalogue_number] => PA 05 0411023
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[weight] => 316.33
[form] => C18H17FO4
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(2R,3R,6S)-6-(4-Fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxylic Acid
Catalogue No.:PA 05 0411023
Molecular Formula : C18H17FO4
Molecular Weight : 316.33
stdClass Object
(
[pname] => 3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoic acid Sodium Salt
[catalogue_number] => PA 05 0411024
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[chemical_name] =>
[weight] => 441.43
[form] => C25H21FNNaO4
[cas] => 1400989-74-3
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3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoic acid Sodium Salt
Catalogue No.:PA 05 0411024
Molecular Formula : C25H21FNNaO4
Molecular Weight : 441.43
stdClass Object
(
[pname] => Di-Desfluoro Ezetimibe
[catalogue_number] => PA 05 0411025
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 373.45
[form] => C24H23NO3
[cas] => 1251741-03-3
[pslug] => 1251741-03-3-di-desfluoro-ezetimibe-pa050411025
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Catalogue No.:PA 05 0411025
Molecular Formula : C24H23NO3
Molecular Weight : 373.45
stdClass Object
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[pname] => (S)-3-((R)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
[catalogue_number] => PA 05 0411026
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[weight] => 357.38
[form] => C20H20FNO4
[cas] => 528565-93-7
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(S)-3-((R)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
Catalogue No.:PA 05 0411026
Molecular Formula : C20H20FNO4
Molecular Weight : 357.38
stdClass Object
(
[pname] => (S)-3-((S)-5-Hydroxy-5-phenylpentanoyl)-4-phenyloxazolidin-2-one
[catalogue_number] => PA 05 0411027
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[weight] => 339.39
[form] => C20H21NO4
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(S)-3-((S)-5-Hydroxy-5-phenylpentanoyl)-4-phenyloxazolidin-2-one
Catalogue No.:PA 05 0411027
Molecular Formula : C20H21NO4
Molecular Weight : 339.39
stdClass Object
(
[pname] => (3S,4R)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one
[catalogue_number] => PA 05 0411028
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[chemical_name] =>
[weight] => 497.54
[form] => C31H25F2NO3
[cas] => NA
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(3S,4R)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one
Catalogue No.:PA 05 0411028
Molecular Formula : C31H25F2NO3
Molecular Weight : 497.54
stdClass Object
(
[pname] => Ezetimibe Open-Ring Anhydro Acid (Z)-Isomer
[catalogue_number] => PA 05 0411029
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[weight] => 409.43
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Ezetimibe Open-Ring Anhydro Acid (Z)-Isomer
Catalogue No.:PA 05 0411029
Molecular Formula : C24H21F2NO3
Molecular Weight : 409.43
stdClass Object
(
[pname] => Ezetimibe Anhydro (Z)-Isomer
[catalogue_number] => PA 05 0411030
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[weight] => 391.42
[form] => C24H19F2NO2
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Ezetimibe Anhydro (Z)-Isomer
Catalogue No.:PA 05 0411030
Molecular Formula : C24H19F2NO2
Molecular Weight : 391.42
stdClass Object
(
[pname] => Tetrahydro-pyran-2-one
[catalogue_number] => PA 05 0411031
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[chemical_name] =>
[weight] => 409.43
[form] => C24H21F2NO3
[cas] => NA
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Catalogue No.:PA 05 0411031
Molecular Formula : C24H21F2NO3
Molecular Weight : 409.43
stdClass Object
(
[pname] => (R)-Ezetimibe Desfluoro Chloro Impurity
[catalogue_number] => PA 05 0411032
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 425.88
[form] => C24H21ClFNO3
[cas] => NA
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(R)-Ezetimibe Desfluoro Chloro Impurity
Catalogue No.:PA 05 0411032
Molecular Formula : C24H21ClFNO3
Molecular Weight : 425.88
stdClass Object
(
[pname] => Benzyl Ezetimibe Diol (Mixture of Diastereomers)
[catalogue_number] => PA 05 0411033
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 503.59
[form] => C31H31F2NO3
[cas] => NA
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Benzyl Ezetimibe Diol (Mixture of Diastereomers)
Catalogue No.:PA 05 0411033
Molecular Formula : C31H31F2NO3
Molecular Weight : 503.59
stdClass Object
(
[pname] => (3R,4S)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
[catalogue_number] => PA 05 0411034
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[chemical_name] =>
[weight] => 315.34
[form] => C18H18FNO3
[cas] => NA
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(3R,4S)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Catalogue No.:PA 05 0411034
Molecular Formula : C18H18FNO3
Molecular Weight : 315.34
stdClass Object
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[catalogue_number] => PA 05 0411035
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[weight] => 383.44
[form] => C23H23F2NO2
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4-((1S,5S)-5-(4-Fluorophenyl)-1-((4-fluorophenyl)amino)-5-hydroxypentyl)phenol
Catalogue No.:PA 05 0411035
Molecular Formula : C23H23F2NO2
Molecular Weight : 383.44
stdClass Object
(
[pname] => (3R,4S)-3-((S)-3-(4-Fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-ol
[catalogue_number] => PA 05 0411036
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[chemical_name] =>
[weight] => 317.36
[form] => C18H20FNO3
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(3R,4S)-3-((S)-3-(4-Fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-ol
Catalogue No.:PA 05 0411036
Molecular Formula : C18H20FNO3
Molecular Weight : 317.36
stdClass Object
(
[pname] => (S)-3-((2S,5R)-5-(4-Fluorophenyl)-2-((R)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
[catalogue_number] => PA 05 0411037
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 572.61
[form] => C33H30F2N2O5
[cas] => NA
[pslug] => s-3-2s-5r-5-4-fluorophenyl-2-r-4-fluorophenyl-amino-4-hydroxyphenyl-methyl-5-hydroxypentanoyl-4-phenyloxazolidin-2-one-pa050411037
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(S)-3-((2S,5R)-5-(4-Fluorophenyl)-2-((R)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
Catalogue No.:PA 05 0411037
Molecular Formula : C33H30F2N2O5
Molecular Weight : 572.61
stdClass Object
(
[pname] => Ezetimibe Trihydroxy Impurity
[catalogue_number] => PA 05 0411038
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 411.45
[form] => C24H23F2NO3
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Ezetimibe Trihydroxy Impurity
Catalogue No.:PA 05 0411038
Molecular Formula : C24H23F2NO3
Molecular Weight : 411.45
stdClass Object
(
[pname] => (S)-1-(2-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione
[catalogue_number] => PA 05 0411039
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[chemical_name] =>
[weight] => 355.37
[form] => C20H18FNO4
[cas] => 2514695-40-8
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(S)-1-(2-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione
Catalogue No.:PA 05 0411039
Molecular Formula : C20H18FNO4
Molecular Weight : 355.37
stdClass Object
(
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[catalogue_number] => PA 05 0411040
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[chemical_name] =>
[weight] => 373.45
[form] => C24H23NO3
[cas] => 1391548-49-4
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9H-Fluoren-9-ylmethyl N-[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]carbamate
Catalogue No.:PA 05 0411040
Molecular Formula : C24H23NO3
Molecular Weight : 373.45
stdClass Object
(
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[catalogue_number] => PA 05 0411041
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[weight] => 411.45
[form] => C24H23F2NO3
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3’-Dehydroxy-1,2-seco Ezetimibe
Catalogue No.:PA 05 0411041
Molecular Formula : C24H23F2NO3
Molecular Weight : 411.45
stdClass Object
(
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[catalogue_number] => PA 05 0411042
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[weight] => 745.97
[form] => C39H45F2N3O6Si2
[cas] => NA
[pslug] => n-4-fluorophenyl-n-1s-2r-5s-5-4-fluorophenyl-2-s-2-oxo-4-phenyloxazolidine-3-carbonyl-5-trimethylsilyl-oxy-1-4-trimethylsilyl-oxy-phenyl-pentyl-nitrous-amide-pa050411042
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N-(4-Fluorophenyl)-N-((1S,2R,5S)-5-(4-fluorophenyl)-2-((S)-2-oxo-4-phenyloxazolidine-3-carbonyl)-5-((trimethylsilyl)oxy)-1-(4-((trimethylsilyl)oxy)phenyl)pentyl)nitrous amide
Catalogue No.:PA 05 0411042
Molecular Formula : C39H45F2N3O6Si2
Molecular Weight : 745.97
stdClass Object
(
[pname] => (3S,4S)-1-(4-Fluorophenyl)-4-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-3-(4-hydroxyphenyl)azetidin-2-one
[catalogue_number] => PA 05 0411046
[category_ids] => ,80,81,78,70,82,
[chemical_name] =>
[weight] => 409.43
[form] => C24H21F2NO3
[cas] => NA
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(3S,4S)-1-(4-Fluorophenyl)-4-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-3-(4-hydroxyphenyl)azetidin-2-one
Catalogue No.:PA 05 0411046
Molecular Formula : C24H21F2NO3
Molecular Weight : 409.43
stdClass Object
(
[pname] => (S)-3-((2S,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
[catalogue_number] => PA 05 0411047
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[chemical_name] =>
[weight] => 716.97
[form] => C39H46F2N2O5Si2
[cas] => NA
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(S)-3-((2S,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
Catalogue No.:PA 05 0411047
Molecular Formula : C39H46F2N2O5Si2
Molecular Weight : 716.97
stdClass Object
(
[pname] => (S)-3-((2S,5S)-5-(4-Fluorophenyl)-2-((R)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
[catalogue_number] => PA 05 0411048
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 716.97
[form] => C39H46F2N2O5Si2
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(S)-3-((2S,5S)-5-(4-Fluorophenyl)-2-((R)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
Catalogue No.:PA 05 0411048
Molecular Formula : C39H46F2N2O5Si2
Molecular Weight : 716.97
stdClass Object
(
[pname] => (3S,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one
[catalogue_number] => PA 05 0411049
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 553.8
[form] => C30H37F2NO3Si2
[cas] => NA
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(3S,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one
stdClass Object
(
[pname] => (3R,4R)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one
[catalogue_number] => PA 05 0411050
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 553.8
[form] => C30H37F2NO3Si2
[cas] => NA
[pslug] => 3r-4r-1-4-fluorophenyl-3-s-3-4-fluorophenyl-3-trimethylsilyl-oxy-propyl-4-4-trimethylsilyl-oxy-phenyl-azetidin-2-one-pa050411050
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(3R,4R)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one
stdClass Object
(
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[catalogue_number] => PA 05 0411051
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 553.8
[form] => C30H37F2NO3Si2
[cas] => 1650568-83-4
[pslug] => 1650568-83-4-3s-4r-1-4-fluorophenyl-3-s-3-4-fluorophenyl-3-trimethylsilyl-oxy-propyl-4-4-trimethylsilyl-oxy-phenyl-azetidin-2-one-pa050411051
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(3S,4R)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one
stdClass Object
(
[pname] => N-Nitroso Ezetimibe Open-Ring Acid
[catalogue_number] => PA 05 0411052
[category_ids] => ,70,78,81,82,
[chemical_name] =>
[weight] => 456.45
[form] => C24H22F2N2O5
[cas] => NA
[pslug] => n-nitroso-ezetimibe-open-ring-acid-pa050411052
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N-Nitroso Ezetimibe Open-Ring Acid
Catalogue No.:PA 05 0411052
Molecular Formula : C24H22F2N2O5
Molecular Weight : 456.45
stdClass Object
(
[pname] => (4S,5R)-4-methyl-5-phenyloxazolidin-2-one
[catalogue_number] => PA 05 0411053
[category_ids] => ,70,78,81,82,
[chemical_name] =>
[weight] => 177.2
[form] => C10H11NO2
[cas] => 16251-45-9
[pslug] => 16251-45-9-4s-5r-4-methyl-5-phenyloxazolidin-2-one-pa050411053
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(4S,5R)-4-methyl-5-phenyloxazolidin-2-one
stdClass Object
(
[pname] => (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((R)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
[catalogue_number] => PA 05 0411054
[category_ids] => ,70,78,81,82,
[chemical_name] =>
[weight] => 572.61
[form] => C33H30F2N2O5
[cas] => 1621715-63-6
[pslug] => 1621715-63-6-s-3-2r-5s-5-4-fluorophenyl-2-r-4-fluorophenyl-amino-4-hydroxyphenyl-methyl-5-hydroxypentanoyl-4-phenyloxazolidin-2-one-pa050411054
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(S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((R)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
Catalogue No.:PA 05 0411054
Molecular Formula : C33H30F2N2O5
Molecular Weight : 572.61
stdClass Object
(
[pname] => 5-Oxo-5-phenylpentanoic Acid
[catalogue_number] => PA 05 0411055
[category_ids] => ,70,78,81,82,
[chemical_name] =>
[weight] => 192.21
[form] => C11H12O3
[cas] => 1501-05-9
[pslug] => 1501-05-9-5-oxo-5-phenylpentanoic-acid-pa050411055
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5-Oxo-5-phenylpentanoic Acid
Catalogue No.:PA 05 0411055
Molecular Formula : C11H12O3
Molecular Weight : 192.21
