flibanserin
Intermediates
- Flibanserin is used for hypoactive sexual desire disorder among women. It is sold under the trade name Addyi. It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder drug by Sprout Pharmaceuticals. Reference standards of Flibanserin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Flibanserin-d4
[catalogue_number] => PA STI 041260
[category_ids] => ,70,78,79,80,82,98,103,
[chemical_name] =>
[weight] => 394.43
[form] => C20H17D4F3N4O
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Catalogue No.:PA STI 041260
Molecular Formula : C20H17D4F3N4O
Molecular Weight : 394.43
stdClass Object
(
[pname] => Flibanserin-d4 HCl (ethylene-d4)
[catalogue_number] => PA STI 088330
[category_ids] => ,98,78,70,82,
[chemical_name] =>
[weight] => 430.89
[form] => C20H18D4ClF3N4O
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Flibanserin-d4 HCl (ethylene-d4)
Catalogue No.:PA STI 088330
Molecular Formula : C20H18D4ClF3N4O
Molecular Weight : 430.89
stdClass Object
(
[pname] => 2-Methylbenzimidazole
[catalogue_number] => PA 33 0091000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 132.17
[form] => C8H8N2
[cas] => 615-15-6
[pslug] => 615-15-6-2-methylbenzimidazole-pa330091000
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Catalogue No.:PA 33 0091000
Molecular Formula : C8H8N2
Molecular Weight : 132.17
stdClass Object
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[catalogue_number] => PA 33 0091001
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[chemical_name] =>
[weight] => 294.31
[form] => C16H14N4O2
[cas] => NA
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1,1'-(Ethane-1,2-diyl)bis(1,3-dihydro-2H-benzo[d]imidazol-2-one)
Catalogue No.:PA 33 0091001
Molecular Formula : C16H14N4O2
Molecular Weight : 294.31
stdClass Object
(
[pname] => 1,3-bis(2-Bromoethyl)-1H-benzo[d]imidazol-2(3H)-one
[catalogue_number] => PA 33 0091002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 348.04
[form] => C11H12Br2N2O
[cas] => 2514955-87-2
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1,3-bis(2-Bromoethyl)-1H-benzo[d]imidazol-2(3H)-one
Catalogue No.:PA 33 0091002
Molecular Formula : C11H12Br2N2O
Molecular Weight : 348.04
stdClass Object
(
[pname] => 3-Carboxyl 3-Detrifluoromethyl Flibanserin
[catalogue_number] => PA 33 0091003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 366.42
[form] => C20H22N4O3
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3-Carboxyl 3-Detrifluoromethyl Flibanserin
Catalogue No.:PA 33 0091003
Molecular Formula : C20H22N4O3
Molecular Weight : 366.42
stdClass Object
(
[pname] => Methyl 3-(4-(2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoate
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[weight] => 380.45
[form] => C21H24N4O3
[cas] => NA
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Methyl 3-(4-(2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoate
Catalogue No.:PA 33 0091004
Molecular Formula : C21H24N4O3
Molecular Weight : 380.45
stdClass Object
(
[pname] => 1,1'-(Piperazine-1,4-diylbis(ethane-2,1-diyl))bis(1,3-dihydro-2H-benzo[d]imidazol-2-one)
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[weight] => 406.49
[form] => C22H26N6O2
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1,1'-(Piperazine-1,4-diylbis(ethane-2,1-diyl))bis(1,3-dihydro-2H-benzo[d]imidazol-2-one)
Catalogue No.:PA 33 0091005
Molecular Formula : C22H26N6O2
Molecular Weight : 406.49
stdClass Object
(
[pname] => 1-(2-(4-(4-Hydroxy-3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
[catalogue_number] => PA 33 0091006
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[chemical_name] =>
[weight] => 406.41
[form] => C20H21F3N4O2
[cas] => 331763-97-4
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1-(2-(4-(4-Hydroxy-3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
Catalogue No.:PA 33 0091006
Molecular Formula : C20H21F3N4O2
Molecular Weight : 406.41
stdClass Object
(
[pname] => Flibanserin N-Oxide
[catalogue_number] => PA 33 0091007
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[weight] => 406.41
[form] => C20H21F3N4O2
[cas] => 2652583-35-0
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Catalogue No.:PA 33 0091007
Molecular Formula : C20H21F3N4O2
Molecular Weight : 406.41
stdClass Object
(
[pname] => 1,3-Dihydro-1-(1-methylethenyl)-3-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one
[catalogue_number] => PA 33 0091008
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 430.48
[form] => C23H25F3N4O
[cas] => 1971858-36-2
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1,3-Dihydro-1-(1-methylethenyl)-3-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one
Catalogue No.:PA 33 0091008
Molecular Formula : C23H25F3N4O
Molecular Weight : 430.48
stdClass Object
(
[pname] => 1,3-bis(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
[catalogue_number] => PA 33 0091009
[category_ids] => ,82,78,76,75,70,
[chemical_name] =>
[weight] => 646.68
[form] => C33H36F6N6O
[cas] => 2518011-18-0
[pslug] => 2518011-18-0-1-3-bis-2-4-3-trifluoromethyl-phenyl-piperazin-1-yl-ethyl-1-3-dihydro-2h-benzo-d-imidazol-2-one-pa330091009
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1,3-bis(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
Catalogue No.:PA 33 0091009
Molecular Formula : C33H36F6N6O
Molecular Weight : 646.68
stdClass Object
(
[pname] => 1-(2-Bromoethyl)-3-(prop-1-en-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
[catalogue_number] => PAI 33 009001
[category_ids] => ,70,
[chemical_name] =>
[weight] => 281.15
[form] => C12H13BrN2O
[cas] => 136081-17-9
[pslug] => 136081-17-9-1-2-bromoethyl-3-prop-1-en-2-yl-1-3-dihydro-2h-benzo-d-imidazol-2-one-pai33009001
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1-(2-Bromoethyl)-3-(prop-1-en-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
Catalogue No.:PAI 33 009001
Molecular Formula : C12H13BrN2O
Molecular Weight : 281.15
stdClass Object
(
[pname] => 1-(2-Bromoethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
[catalogue_number] => PAI 33 009002
[category_ids] => ,70,
[chemical_name] =>
[weight] => 241.09
[form] => C9H9BrN2O
[cas] => 103784-03-8
[pslug] => 103784-03-8-1-2-bromoethyl-1-3-dihydro-2h-benzo-d-imidazol-2-one-pai33009002
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1-(2-Bromoethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
Catalogue No.:PAI 33 009002
Molecular Formula : C9H9BrN2O
Molecular Weight : 241.09
stdClass Object
(
[pname] => 3,3'-(Ethane-1,2-diyl)bis(1-(prop-1-en-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one)
[catalogue_number] => PAI 33 009003
[category_ids] => ,70,
[chemical_name] =>
[weight] => 374.44
[form] => C22H22N4O2
[cas] => NA
[pslug] => 3-3-ethane-1-2-diyl-bis-1-prop-1-en-2-yl-1-3-dihydro-2h-benzo-d-imidazol-2-one-pai33009003
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3,3'-(Ethane-1,2-diyl)bis(1-(prop-1-en-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one)
Catalogue No.:PAI 33 009003
Molecular Formula : C22H22N4O2
Molecular Weight : 374.44
stdClass Object
(
[pname] => 2-Ethoxy-1H-benzo[d]imidazole
[catalogue_number] => PAI 33 009004
[category_ids] => ,70,
[chemical_name] =>
[weight] => 162.19
[form] => C9H10N2O
[cas] => 22219-23-4
[pslug] => 22219-23-4-2-ethoxy-1h-benzo-d-imidazole-pai33009004
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2-Ethoxy-1H-benzo[d]imidazole
Catalogue No.:PAI 33 009004
Molecular Formula : C9H10N2O
Molecular Weight : 162.19
stdClass Object
(
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[catalogue_number] => PAI 33 009005
[category_ids] => ,70,
[chemical_name] =>
[weight] => 350.42
[form] => C20H22N4O2
[cas] => NA
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1,2-Bis(2-ethoxy-1H-benzo[d]imidazol-1-yl)ethane
Catalogue No.:PAI 33 009005
Molecular Formula : C20H22N4O2
Molecular Weight : 350.42
stdClass Object
(
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[catalogue_number] => PAI 33 009006
[category_ids] => ,70,
[chemical_name] =>
[weight] => 224.69
[form] => C11H13ClN2O
[cas] => 1971858-37-3
[pslug] => 1971858-37-3-1-2-chloroethyl-2-ethoxy-1h-benzo-d-imidazole-pai33009006
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1-(2-Chloroethyl)-2-ethoxy-1H-benzo[d]imidazole
Catalogue No.:PAI 33 009006
Molecular Formula : C11H13ClN2O
Molecular Weight : 224.69
stdClass Object
(
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[catalogue_number] => PAI 33 009007
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[chemical_name] =>
[weight] => 374.49
[form] => C20H30N4O3
[cas] => NA
[pslug] => tert-butyl-4-2-2-ethoxy-1h-benzo-d-imidazol-1-yl-ethyl-piperazine-1-carboxylate-pai33009007
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tert-Butyl 4-(2-(2-ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazine-1-carboxylate
Catalogue No.:PAI 33 009007
Molecular Formula : C20H30N4O3
Molecular Weight : 374.49
stdClass Object
(
[pname] => 2-Ethoxy-1-(2-(piperazin-1-yl)ethyl)-1H-benzo[d]imidazole
[catalogue_number] => PAI 33 009008
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[chemical_name] =>
[weight] => 274.37
[form] => C15H22N4O
[cas] => NA
[pslug] => 2-ethoxy-1-2-piperazin-1-yl-ethyl-1h-benzo-d-imidazole-pai33009008
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2-Ethoxy-1-(2-(piperazin-1-yl)ethyl)-1H-benzo[d]imidazole
Catalogue No.:PAI 33 009008
Molecular Formula : C15H22N4O
Molecular Weight : 274.37
stdClass Object
(
[pname] => 2-Ethoxy-1-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazole
[catalogue_number] => PAI 33 009009
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[chemical_name] =>
[weight] => 418.46
[form] => C22H25F3N4O
[cas] => 1971858-38-4
[pslug] => 1971858-38-4-2-ethoxy-1-2-4-3-trifluoromethyl-phenyl-piperazin-1-yl-ethyl-1h-benzo-d-imidazole-pai33009009
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2-Ethoxy-1-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazole
Catalogue No.:PAI 33 009009
Molecular Formula : C22H25F3N4O
Molecular Weight : 418.46
stdClass Object
(
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[catalogue_number] => PAI 33 009010
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[chemical_name] =>
[weight] => 462.6
[form] => C26H34N6O2
[cas] => NA
[pslug] => 1-4-bis-2-2-ethoxy-1h-benzo-d-imidazol-1-yl-ethyl-piperazine-pai33009010
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1,4-Bis(2-(2-ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazine
stdClass Object
(
[pname] => 1,3-Bis(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one Dihydrochloride
[catalogue_number] => PA 33 0091010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 719.6
[form] => C33H38Cl2F6N6O
[cas] => NA
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1,3-Bis(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one Dihydrochloride
stdClass Object
(
[pname] => Methyl 3-(4-(2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoate Hydrochloride
[catalogue_number] => PA 33 0091011
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 416.91
[form] => C21H25ClN4O3
[cas] => NA
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Methyl 3-(4-(2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoate Hydrochloride
Catalogue No.:PA 33 0091011
Molecular Formula : C21H25ClN4O3
Molecular Weight : 416.91
stdClass Object
(
[pname] => 3-(4-(2-(2-Ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoic Acid
[catalogue_number] => PAI 33 009012
[category_ids] => ,70,
[chemical_name] =>
[weight] => 394.48
[form] => C22H26N4O3
[cas] => NA
[pslug] => 3-4-2-2-ethoxy-1h-benzo-d-imidazol-1-yl-ethyl-piperazin-1-yl-benzoic-acid-pai33009012
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3-(4-(2-(2-Ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoic Acid
Catalogue No.:PAI 33 009012
Molecular Formula : C22H26N4O3
Molecular Weight : 394.48
stdClass Object
(
[pname] => Methyl 3-(4-(2-(2-ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoate
[catalogue_number] => PAI 33 009013
[category_ids] => ,70,
[chemical_name] =>
[weight] => 408.5
[form] => C23H28N4O3
[cas] => NA
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Methyl 3-(4-(2-(2-ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)benzoate
stdClass Object
(
[pname] => tert-Butyl 4-(3-(methoxycarbonyl)phenyl)piperazine-1-carboxylate
[catalogue_number] => PAI 33 009014
[category_ids] => ,70,
[chemical_name] =>
[weight] => 320.39
[form] => C17H24N2O4
[cas] => 179003-10-2
[pslug] => 179003-10-2-tert-butyl-4-3-methoxycarbonyl-phenyl-piperazine-1-carboxylate-pai33009014
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tert-Butyl 4-(3-(methoxycarbonyl)phenyl)piperazine-1-carboxylate
Catalogue No.:PAI 33 009014
Molecular Formula : C17H24N2O4
Molecular Weight : 320.39
stdClass Object
(
[pname] => Methyl 3-(piperazin-1-yl)benzoate Hydrochloride
[catalogue_number] => PAI 33 009015
[category_ids] => ,70,
[chemical_name] =>
[weight] => 256.73
[form] => C12H17ClN2O2
[cas] => 2208746-53-4
[pslug] => 2208746-53-4-methyl-3-piperazin-1-yl-benzoate-hydrochloride-pai33009015
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Methyl 3-(piperazin-1-yl)benzoate Hydrochloride
Catalogue No.:PAI 33 009015
Molecular Formula : C12H17ClN2O2
Molecular Weight : 256.73
stdClass Object
(
[pname] => 3-Carboxyl 3-Detrifluoromethyl Flibanserin Hydrochloride
[catalogue_number] => PA 33 0091012
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 402.88
[form] => C20H23ClN4O3
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3-Carboxyl 3-Detrifluoromethyl Flibanserin Hydrochloride
Catalogue No.:PA 33 0091012
Molecular Formula : C20H23ClN4O3
Molecular Weight : 402.88
stdClass Object
(
[pname] => 4-Iodo-2-(trifluoromethyl)phenol
[catalogue_number] => PAI 33 009016
[category_ids] => ,70,
[chemical_name] =>
[weight] => 288.01
[form] => C7H4F3IO
[cas] => 1132942-88-1
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4-Iodo-2-(trifluoromethyl)phenol
Catalogue No.:PAI 33 009016
Molecular Formula : C7H4F3IO
Molecular Weight : 288.01
stdClass Object
(
[pname] => tert-Butyl 4-(4-hydroxy-3-(trifluoromethyl)phenyl)piperazine-1-carboxylate
[catalogue_number] => PAI 33 009017
[category_ids] => ,70,
[chemical_name] =>
[weight] => 346.35
[form] => C16H21F3N2O3
[cas] => NA
[pslug] => tert-butyl-4-4-hydroxy-3-trifluoromethyl-phenyl-piperazine-1-carboxylate-pai33009017
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tert-Butyl 4-(4-hydroxy-3-(trifluoromethyl)phenyl)piperazine-1-carboxylate
Catalogue No.:PAI 33 009017
Molecular Formula : C16H21F3N2O3
Molecular Weight : 346.35
stdClass Object
(
[pname] => 4-(Piperazin-1-yl)-2-(trifluoromethyl)phenol Hydrochloride
[catalogue_number] => PAI 33 009018
[category_ids] => ,70,
[chemical_name] =>
[weight] => 282.69
[form] => C11H14ClF3N2O
[cas] => NA
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4-(Piperazin-1-yl)-2-(trifluoromethyl)phenol Hydrochloride
Catalogue No.:PAI 33 009018
Molecular Formula : C11H14ClF3N2O
Molecular Weight : 282.69
stdClass Object
(
[pname] => 4-(4-(2-(2-Ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)-2-(trifluoromethyl)phenol
[catalogue_number] => PAI 33 009019
[category_ids] => ,70,
[chemical_name] =>
[weight] => 434.46
[form] => C22H25F3N4O2
[cas] => NA
[pslug] => 4-4-2-2-ethoxy-1h-benzo-d-imidazol-1-yl-ethyl-piperazin-1-yl-2-trifluoromethyl-phenol-pai33009019
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4-(4-(2-(2-Ethoxy-1H-benzo[d]imidazol-1-yl)ethyl)piperazin-1-yl)-2-(trifluoromethyl)phenol
Catalogue No.:PAI 33 009019
Molecular Formula : C22H25F3N4O2
Molecular Weight : 434.46
