Larotrectinib
Larotrectinib (tradename Vitrakvi) is a drug for the treatment of cancer.It is an inhibitor of tropomyosin kinase receptors TrkA, TrkB, and TrkC. It was discovered by Array BioPharma and licensed to Loxo Oncology in 2013. Reference standards of Larotrectinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Larotrectinib
[catalogue_number] => PA 12 1480000
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 428.44
[form] => C21H22F2N6O2
[cas] => 1223403-58-4
[pslug] => 1223403-58-4-larotrectinib-api-pa121480000
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Catalogue No.:PA 12 1480000
Molecular Formula : C21H22F2N6O2
Molecular Weight : 428.44
stdClass Object
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[pname] => (S)-N-(5-Chloropyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
[catalogue_number] => PA 12 1481000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 281.7
[form] => C11H12ClN5O2
[cas] => 2226370-52-9
[pslug] => 2226370-52-9-s-n-5-chloropyrazolo-1-5-a-pyrimidin-3-yl-3-hydroxypyrrolidine-1-carboxamide-pa121481000
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(S)-N-(5-Chloropyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
stdClass Object
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[pname] => (S)-1-benzyl-3-hydroxypyrrolidine-2,5-dione
[catalogue_number] => PA 12 1481002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 205.21
[form] => C11H11NO3
[cas] => 101469-91-4
[pslug] => 101469-91-4-s-1-benzyl-3-hydroxypyrrolidine-2-5-dione-pa121481002
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(S)-1-benzyl-3-hydroxypyrrolidine-2,5-dione
Catalogue No.:PA 12 1481002
Molecular Formula : C11H11NO3
Molecular Weight : 205.21
stdClass Object
(
[pname] => (S)-1-benzylpyrrolidin-3-ol
[catalogue_number] => PA 12 1481001
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[chemical_name] =>
[weight] => 177.25
[form] => C11H15NO
[cas] => 101385-90-4
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(S)-1-benzylpyrrolidin-3-ol
Catalogue No.:PA 12 1481001
Molecular Formula : C11H15NO
Molecular Weight : 177.25
stdClass Object
(
[pname] => Larotrectinib Open-Ring Dimer
[catalogue_number] => PA 12 1481003
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 515.57
[form] => C25H31F2N7O3
[cas] => NA
[pslug] => larotrectinib-open-ring-dimer-pa121481003
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Larotrectinib Open-Ring Dimer
Catalogue No.:PA 12 1481003
Molecular Formula : C25H31F2N7O3
Molecular Weight : 515.57
