ledipasvir
Ledipasvir is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. Reference standards of Ledipasvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Ledipasvir
[catalogue_number] => PA 12 77000
[category_ids] => ,79,80,77,69,71,78,70,82,
[chemical_name] =>
[weight] => 889.00
[form] => C49H54F2N8O6
[cas] => 1256388-51-8
[pslug] => 1256388-51-8-ledipasvir-api-pa1277000
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Catalogue No.:PA 12 77000
Molecular Formula : C49H54F2N8O6
Molecular Weight : 889.00
stdClass Object
(
[pname] => Ledipasvir-d6
[catalogue_number] => PA STI 056231
[category_ids] => ,79,80,77,69,71,98,78,70,82,
[chemical_name] =>
[weight] => 895.04
[form] => C49H48D6F2N8O6
[cas] => NA
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Catalogue No.:PA STI 056231
Molecular Formula : C49H48D6F2N8O6
Molecular Weight : 895.04
stdClass Object
(
[pname] => Methyl ((S)-1-((S)-6-(5-(7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9-oxo-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
[catalogue_number] => PA 12 77580
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 867.02
[form] => C49H54N8O7
[cas] => 2040487-43-0
[pslug] => 2040487-43-0-methyl-s-1-s-6-5-7-2-1r-3s-4s-2-methoxycarbonyl-l-valyl-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazol-6-yl-9-oxo-9h-fluoren-2-yl-1h-imidazol-2-yl-5-azaspiro-2-4-heptan-5-yl-3-methyl-1-oxobutan-2-yl-carbamate-pa1277580
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Methyl ((S)-1-((S)-6-(5-(7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9-oxo-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
Catalogue No.:PA 12 77580
Molecular Formula : C49H54N8O7
Molecular Weight : 867.02
stdClass Object
(
[pname] => Methyl ((R)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
[catalogue_number] => PA 12 0771000
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[weight] => 889
[form] => C49H54F2N8O6
[cas] => 1256393-35-7
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Methyl ((R)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
stdClass Object
(
[pname] => Methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-D-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
[catalogue_number] => PA 12 0771001
[category_ids] => ,78,75,70,76,82,
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[weight] => 889
[form] => C49H54F2N8O6
[cas] => 1256391-66-8
[pslug] => 1256391-66-8-methyl-s-1-s-6-5-9-9-difluoro-7-2-1r-3s-4s-2-methoxycarbonyl-d-valyl-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazol-6-yl-9h-fluoren-2-yl-1h-imidazol-2-yl-5-azaspiro-2-4-heptan-5-yl-3-methyl-1-oxobutan-2-yl-carbamate-pa120771001
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Methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-D-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
stdClass Object
(
[pname] => Ledipasvir 1S,3R,4R-Diastereomer
[catalogue_number] => PA 12 0771002
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 889
[form] => C49H54F2N8O6
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Ledipasvir 1S,3R,4R-Diastereomer
stdClass Object
(
[pname] => Ledipasvir 1S,3S,4R-Diastereomer
[catalogue_number] => PA 12 0771003
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[weight] => 889
[form] => C49H54F2N8O6
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Ledipasvir 1S,3S,4R-Diastereomer
stdClass Object
(
[pname] => (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic Acid;
[catalogue_number] => PA 12 0771004
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 241.29
[form] => C12H19NO4
[cas] => 1129634-44-1
[pslug] => 1129634-44-1-s-5-tert-butoxycarbonyl-5-azaspiro-2-4-heptane-6-carboxylic-acid-pa120771004
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(S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic Acid;
Catalogue No.:PA 12 0771004
Molecular Formula : C12H19NO4
Molecular Weight : 241.29
stdClass Object
(
[pname] => Ledipasvir D8
[catalogue_number] => PA STI 089132
[category_ids] => ,98,75,76,78,70,82,
[chemical_name] =>
[weight] => 897.07
[form] => C49H46D8F2N8O6
[cas] => NA
[pslug] => ledipasvir-d8-pasti089132
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Catalogue No.:PA STI 089132
Molecular Formula : C49H46D8F2N8O6
Molecular Weight : 897.07
stdClass Object
(
[pname] => Ledipasvir Acetyl Spiro Impurity
[catalogue_number] => PA 12 0771005
[category_ids] => ,79,80,77,69,71,78,70,82,
[chemical_name] =>
[weight] => 773.89
[form] => C44H45F2N7O4
[cas] => 2040487-36-1
[pslug] => 2040487-36-1-ledipasvir-acetyl-spiro-impurity-pa120771005
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Ledipasvir Acetyl Spiro Impurity
Catalogue No.:PA 12 0771005
Molecular Formula : C44H45F2N7O4
Molecular Weight : 773.89
stdClass Object
(
[pname] => 6-(7-(2-((S)-5-Azaspiro[2.4]heptan-6-yl)-1H-imidazol-5-yl)-9,9-difluoro-9H-fluoren-2-yl)-2-((1R,3S,4S)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazole tetrahydrochloride
[catalogue_number] => PA 12 0771007
[category_ids] => ,79,80,77,69,71,78,70,82,
[chemical_name] =>
[weight] => 720.51
[form] => C35H36Cl4F2N6
[cas] => 1499193-67-7
[pslug] => 1499193-67-7-6-7-2-s-5-azaspiro-2-4-heptan-6-yl-1h-imidazol-5-yl-9-9-difluoro-9h-fluoren-2-yl-2-1r-3s-4s-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazole-tetrahydrochloride-pa120771007
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6-(7-(2-((S)-5-Azaspiro[2.4]heptan-6-yl)-1H-imidazol-5-yl)-9,9-difluoro-9H-fluoren-2-yl)-2-((1R,3S,4S)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazole tetrahydrochloride
Catalogue No.:PA 12 0771007
Molecular Formula : C35H36Cl4F2N6
Molecular Weight : 720.51
stdClass Object
(
[pname] => Acetyl-L-threonine
[catalogue_number] => PA 12 0771006
[category_ids] => ,70,78,79,80,82,
[chemical_name] =>
[weight] => 161.16
[form] => C6H11NO4
[cas] => 17093-74-2
[pslug] => 17093-74-2-acetyl-l-threonine-pa120771006
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Catalogue No.:PA 12 0771006
Molecular Formula : C6H11NO4
Molecular Weight : 161.16
